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Can you predict future brain damage? Hundreds of pro fighters are helping researchers find out

Close to 700 boxers and MMA fighters have joined an ambitious effort to identify subtle signs of trauma-induced brain damage long before symptoms emerge.

LAS VEGAS — It’s a study that probably couldn’t be conducted anywhere other than this hot spot for professional combatants, where marquee fights are about as common as Celine Dion concerts.

Researchers have enrolled close to 700 mixed martial arts fighters and boxers, both active and retired, in the past six years. The ambitious goal: to learn to identify early signs of trauma-induced brain damage from subtle changes in blood chemistry, brain imaging, and performance tests — changes that may show up decades before visible symptoms such as cognitive impairment, depression, and impulsive behavior.

Among the participants is 29-year-old Gina Mazany. She has a streak of pinkish-purple hair, a tattoo of a pterodactyl with a cheeseburger in its beak, and a reputation as a formidable MMA fighter worthy of her nickname, Gina Danger. Once a year, she undergoes a battery of medical tests here at the , an outpost of the of a career marked by concussions and blows to the head.

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