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Nanoparticulate Drug Delivery: Perspectives on the Transition from Laboratory to Market
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Nanotechnology-based therapeutics, operating at scales of billionths of a metre, have great potential for future expansion in altering the scale and methods of drug delivery. The availability of these novel formulations to once-inaccessible areas of the body has greatly expanded the therapeutic window of existing drug molecules. Nanoparticulate drug delivery highlights and examines the transition of nanoparticulate drug delivery systems from the laboratory into a commercially viable sector. The first chapters of the book provide an overview of the use and characterization of nanoparticulate systems as drug carriers, including the assessment of their morphology, sterility and potential toxicity. In the latter part of the book, chapters cover nanotoxicology, regulatory aspect and clinical trials, ending with an overview of several case studies and a look towards future developments.
- Discusses the issues surrounding nanoparticulate products, based on personal experience of their formulation
- Provides an overview of new application areas, including RNA interference
- Outlines the pros and cons of nanoparticulate products, and discusses how these may influence their route into the commercial sector
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Vandana Patravale
Dr. Vandana B. Patravale is currently a Professor of Pharmaceutics at the Institute of Chemical Technology, Mumbai, India. She has 30 years of teaching and research experience. Prof. Patravale has over 200 refereed publications, 11 granted patents, 24 patents in the pipeline, and 2 trademark registries, and has published 2 books and 25 book chapters. She is an international advisory committee member of AAPS and Vice President of the CRS Indian chapter. She has acted as an editorial board member or guest editor for numerous journals, and has active collaborations with researchers and industries within the country and abroad. Prof. Patravale has successfully transferred many technologies to industry, the most recent being drug-eluting stents which are currently marketed in more than 60 countries.
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