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    MIT HYPOTHESIS- Evidences From Research Database
    MIT HYPOTHESIS- Evidences From Research Database
    MIT HYPOTHESIS- Evidences From Research Database
    Ebook50 pages39 minutes

    MIT HYPOTHESIS- Evidences From Research Database

    By Chandran K C

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    About this ebook

    According to MIT HYPOTHESIS, active principles of post-avogadro potentized drugs are MOLECULAR IMPRINTS of individual chemical molecules contained in the drug substances used for potentization. As per this hypothesis, 'molecular imprints' are hydrogen-bonded supramolecular formations of water-ethyl alcohol molecules, into which the three-dimensional spacial conformations of drug molecules are imprinted or engraved as nanocavities, through a process of host-guest interactions or MOLECULAR IMPRINTING involved in the process of potentization. These 'molecular imprints' can act as artificial binding sites or key holes for binding to the original drug molecules as well as any pathogenic molecule conformationally similar to the drug molecules. When applied as therapeutic agent, these molecular imprints specifically bind to the pathogenic molecules having conformational affinity, thereby deactivating them and relieving the biological molecules from pathological molecular inhibitions. This is the biological mechanism of homeopathic cure as proposed by MIT HYPOTHESIS.

    Actually, the biological mechanism of cure proposed in this model is not a new idea. It is well accepted in modern molecular medicine and pharmacology, and is the basis of target-specific drug designing techniques currently very popular in pharmaceutical researches. There remains nothing to be proved on this idea.
    Molecular imprinting in polymers (MIP) also is recently a very popular research area, a technique used in developing artificial binding sites in polymer matrices through a process of molecular level 'host-guest' interactions. These 'molecular imprinted polymers' are currently utilized in various laboratory procedures as molecular binding and filtering agents. What I have been trying to do by MIT hypothesis is to adapt these well-accepted scientific concepts into the theoretical frame work of homeopathy, so that a scientific model could be developed to explain the biological mechanism of homeopathic cure. MIT hypothesis explains homeopathic potentization in terms of 'molecular imprinting in water', and homeopathic cure in terms of removal of molecular inhibitions. Only thing remaining to be scientifically proved is that potentized homeopathic drugs contain 'molecular imprints'. It raises the question whether water-ethyl alcohol mixture can act as a medium for molecular imprinting, similar to polymers. Various studies regarding supra molecular properties of water indicate some 'polymer-like' properties of water and formations of hydrogen-bonded nanoclusters in a micro-environment, which obviously opens up possibilities of molecular imprinting in water-ethyl alcohol matrix.

    LanguageEnglish
    PublisherChandran K C
    Release dateJun 15, 2018
    ISBN9780463501030
    MIT HYPOTHESIS- Evidences From Research Database
    Author

    Chandran K C

    Chandran K C Pioneering a Scientific Revolution in Homeopathy In late sixtees, a 20 year old zoology degree student already armed with the theoretical tools of dialectical methodology, accidently happened to fall into the great ocean of wonderful knowledge of homeopathy, started loving, questioning, learning, exploring, experimenting, and applying it in a way totally different from that of his predecessors. Later in his life, he even dared to quit his job in animal husbandry department under government of kerala, to dedicate his whole time and energy for homeopathy. ‘SIMILIMUM ULTRA HOMEOPATHIC SOFTWARE’ & the book, ‘REDEFINING HOMEOPATHY – as Molecular Imprints Therapeutics’ are the final outcomes of that life devoted for homeopathy for last forty eight years. He is 67 years now. He was the founder of the prestigious Kannur District Homeopathic Hospital Society, establishing a chain of hospitals and clinics for the promotion of homeopathy. Now, he is engaged in serious studies and research activities for proving his scientific explanations of homeopathy, which is expected to revolutionize not only homeopathy, but the whole medical science and pharmaceutical industry in the coming days Email: similimum@gmail.com Mobile: +91 9446 520 252 Address: KC House, Malappattam- 670631, Kannur, Kerala, India

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      Book preview

      MIT HYPOTHESIS- Evidences From Research Database - Chandran K C

      MIT HYPOTHESIS

      Evidences from Research Database

      By Chandran K C

      Copyright 1018 Chandran K C

      A Smashwords Edition

      Chapter 1. Introduction

      According to MIT HYPOTHESIS, active principles of post-avogadro potentized drugs are MOLECULAR IMPRINTS of individual chemical molecules contained in the drug substances used for potentization.

      As per this hypothesis, 'molecular imprints' are hydrogen-bonded supramolecular formations of  water-ethyl alcohol molecules, into which the three-dimensional  spacial conformations of drug molecules are imprinted or engraved as nanocavities, through a process of host-guest interactions or  MOLECULAR IMPRINTING  involved in the process of potentization.

      These 'molecular imprints' can act as artificial binding sites or key holes for binding to the original drug molecules as well as any pathogenic molecule conformationally similar to the drug molecules.

      When applied as therapeutic agent, these molecular imprints specifically bind to the pathogenic molecules having conformational affinity, thereby deactivating them and relieving the biological molecules from pathological molecular inhibitions.

      This is the biological mechanism of homeopathic cure as proposed by MIT HYPOTHESIS.

      Actually, the biological mechanism of cure proposed in this model is not a new idea. It is well accepted in modern molecular medicine and pharmacology, and is the basis of target-specific drug designing techniques currently very popular in pharmaceutical researches. There remains nothing to be proved on this idea.

      Molecular imprinting in polymers (MIP) also is recently a very popular research area, a technique used in developing artificial binding sites in polymer matrices through a process of molecular level 'host-guest' interactions. These 'molecular imprinted polymers' are currently utilized in various laboratory procedures as molecular binding and filtering agents.

      What I have been trying to do by MIT hypothesis is to adapt these well-accepted scientific concepts into the theoretical frame work of homeopathy, so that a scientific model could be developed to explain the biological mechanism of homeopathic cure. MIT hypothesis explains homeopathic potentization in terms of 'molecular imprinting in water', and homeopathic cure in terms of removal of molecular inhibitions.

      Only thing remaining to be scientifically proved is that potentized homeopathic drugs contain 'molecular imprints'. It raises the question whether water-ethyl alcohol mixture can act as a medium for molecular imprinting, similar to polymers. Various studies regarding supra molecular properties of water indicate some 'polymer-like' properties of water and formations of hydrogen-bonded nanoclusters in a micro-environment, which obviously opens up possibilities of molecular imprinting in water-ethyl alcohol matrix.

      IF WE COULD EXPERIMENTALLY PROVE the following statements, MIT hypothesis could be considered ratified:

      a) High dilution drugs really work as curative agents when applied according to indications,

      b) High dilution drugs works not only in living bodies, but also up on 'in vitro' biological samples,

      c) High dilution drugs cannot interfere or prevent the normal interactions between biological molecules and their natural ligands,

      d) High dilution drugs can antidote the biological effects of same drugs used in crude or molecular forms,

      e) Biological properties of high dilution drugs are different or reverse to those of same drugs in molecular forms,

      f) High dilution drugs do not contain original drug molecules,

      g) High dilution drugs and unpotentized water-alcohol mixture are similar in their chemical structure and properties,

      h) High dilution drugs differ from unpotentized water-alcohol

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