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DRUG STUDY

Generic Name Brand Name Classiification Indication Contraindication Mode Of Action Actual Dose Usual Dose Side effects Nursing Responsibilities

metronidazole

Flagyl

Antibiotic Antibacterial Amebicide Antiprotozoal

Acute infection with susceptible anaerobic bacteria Acute intestinal amoebiasis

Active organic disease of the CNS Drug Allergy Blood dyscrasia

Inhibits growth of amoebae by binding to DNA, resulting in loss of helical structure, strand breakage, inhibition of nucleic acid synthesis and cell death.

125mg/5mL, 2.5mL every 8 hours

3550mg/kg/day in three doses

Headache, Nausea, dry mouth, vomiting, diarrhea

Observe the 10 Rs before giving the drug. Instruct to take drug with food or milk to decrease GI upset Inform that drug may turn urine brown, dont be alarmed

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