Vous êtes sur la page 1sur 2

Glycolysis 1. 2. 3. 4. 5. 6. 7. 8. 9. 10.

Glucose to glucose-6-phospate; hexokinase Glucose-6-phosphate to fructose-6-phosphate; phosphoglucoisomerase Fructose-6-phsophate to fructose-1,6-bisphosphate; phosphorfructokinase Fructose-1,6-bisphosphate to Dihydroxyacetone phosphate to glyceraldehyde-3-phosphate; aldolase Dihydroxyacetone phosphate to glyceraldehyde-3-phosphate; triose phosphate isomerase Glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate; g-3p dehydrogenase 1,3-bisphosphoglycerate to 3-phosphoglycerate; phosphoglycerate kinase 3-phosphoglycerate to 2-phosphoglycerate; phosphoglycerate mutase 2-phosphoglycerate to phosphoenol pyruvate; enolase Phosphoenolpyruvate to pyruvate; pyruvate kinase

Citric Acid Cycle/ Krebs Cycle/ Tricarboxylic Acid Cycle 1. CONDENSATION of oxaloacetate and Acetyl-CoA to citrate catalyzed by citrate synthetase 2. REVERSIBLE ISOMERIZATION of citrate to isocitrate catalyzed by aconitase involves dehydration to cis-aconitase and hydration to isocitrate 3. OXIDATIVE CARBOXYLATION/ 1ST OXIDATION of isocitrate to alpha-ketoglutarate catalyzed by isocitrate dehydrogenase involves reduction of NAD to oxalosuccinate and release of CO2 to
+

alpha-keto glutarate
4. OXIDATIVE DECARBOXYLATION/ 2ND OXIDATION of alpha-ketoglutarate to succinyl-CoA catalyzed by alpha-ketoglutarate dehydrogenase involves release of CO2 and NADH and attaches to CoA 5. SUBSTRATE LEVEL PHOPHORYLATION of succinyl-CoA to Succinate catalyzed by succinyl-CoA synthetase, release of GDP to GTP 6. OXIDATION of succinate to fumarate catalyzed by succinate dehydrogenase involves reduction of FAD+ 7. HYDRATION of fumarate to malate catalyzed by fumarase 8. FINAL OXIDATION of malate to oxaloacetate by malate dehydrogenase Pentose Phosphate Pathway a. Oxidative i. Glu-6p to 1. Glu-6-phasphate dehydrogenase ii. 6-phosphogluconolactone 1. 6-phosphogluconate dehydrogenase iii. Ribulose-5-p b. Non-oxidative

i. Ribulose-5-p 1. Phosphopentose isomerase 2. Phosphopentose epimerase ii. Ribose-5-p Xylulose-5-p 1. transketolase iii. Glceraldehyde-3-p Sedoheptulose-7-p 1. Transaldolase iv. Fru-6-p Erythrose-4-p v. Erythrose-4-p transketolase Fru-6-p Xylulose-5-p g-3-p Gluconeogenesis 1. 2. 3. Pyruvate, glycerol, lactate, Amino acid Pyruvic acid to PEP, catalyzed by pyruvate carboxylase and PEP carboxykinase Fru-1,6-bisphospahte to fru-1-p by fru-1,6-bisphosphatase Glu-6-p to glu by glu-6phosphatase

Glycogenolysis 1. Glycogen breakdown to glu-1-p by glycogen phosphorylase 2. Glycogen branch breakdown to glu-1-p by glucan transferase and debranching enzyme 3. Glu-1-p isomerizes to glu-6-p by phosphoglucomutase Glycogenesis 1. Glu-6-p to glu-1-p by phosphoglucomutase 2. Glu-1-p with uridine triphosphate to produce UDP-glucose by UDP-glucose pyrophosphorylase

Vous aimerez peut-être aussi