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Genus and Species Disease produce Infective stage Definitive host Portal of entry Manner of transmission Habitat Pathogenic stage Locomotive apparatus Motility Nuclear karyosome Mode of reproduction Pathogenesis Type of encysment Laboratory diagnosis

Entamoeba histolytica Amoebiasis Amoebic dysentery Extraintestinal amoebiasis Cyst Man Mouth Ingestion of mature cyst through contaminated food or drinks Cecum Trophozoite Pseudopodia (Finger-like) Active, Progressive, Directional Centrally (Bulls eye) Binary fission Lytic necrosis Protective and Reproductive Demonstration of organism in stool Metronidazole Ingested RBC Bulls eye karyosome Cigar-shaped 4 nuclei 2 Bulls eye karyosome

Rhizopodea Entamoeba coli Endolimax nana Non-pathogenic/Commensal Non-pathogenic/Commensal Cyst Man Mouth Ingestion of mature cyst through contaminated food or drinks Cecum None Pseudopodia (short and blunt) Sluggish, non-progressive, non-directional Eccentric Binary fission Non-pathogenic Protective and Reproductive Demonstration of organism in stool Metronidazole Cyst Man Mouth Ingestion of mature cyst through contaminated food or drinks Cecum None Pseudopodia (short and blunt) Sluggish Central/Eccentric, blot-like Binary fission Non-pathogenic Protective and Reproductive Demonstration of organism in stool Metronidazole

Iodamoeba butschlii Non-pathogenic/ Commensal Cyst Man Mouth Ingestion of mature cyst through contaminated food or drinks Cecum None Pseudopodia (short and blunt) Sluggish Centrally Binary fission Non-pathogenic Protective and Reproductive Demonstration of organism in stool Metronidazole Glycogen vacuole occupying 1/3 of the cytoplasm

Entamoeba hartmanni Non-pathogenic/ Commensal Cyst Man Mouth Ingestion of mature cyst through contaminated food or drinks Cecum None Pseudopodia Sluggish Centrally Binary fission Non-pathogenic Protective and Reproductive Demonstration of organism in stool Metronidazole

15 Treatment Trophozoite Stage 1 Pathognomonic/ Diagnostic Cystic Stage 1 Chromosomal body 2 Total no. of nucleus 3 No. of nuclear division 4 Pathognomonic/ Diagnostic

Whisk broom appearance 8 nuclei 3 Jagged/splintered chromatoidal bodies

Comma-shaped or bacilliform 4 nuclei 2 Ground glass appearance Cross eyed or Punched out karyosome

Clear chromatin 1 nucleus (usually) Glycogen vacuole occupying 2/3 of cytoplasm, deep mahogany brown color, perikaryosomal

Rice grain 4 nuclei

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