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TUTORIAL SBD2043 NOV 2012 1. Define core test, specialized test and emergency test. Give 2 examples of each.

2. Discuss on how error could happen during sampling procedures. 3. What are the pre-analytical errors that may affect the quality assurance in a lab? 4. Explain factors that lead to hemolysis. 5. Expect the abnormal reading of a hemolysed sample. 6. Explain these enzyme reaction a. Transferase b. Hydrolase c. Ligase 7. Complete the table below: Enzyme Bone tumour Cardiac disease Hepatic disease 8. Write a. b. c. d. e. f. g. the origin and cancers that associate with these tumor markers: Alpha Feto Protein Human Chorionic Gonadotrophine Alkaline Phosphatase Adrenocotricotrophine hormone Thyroid stimulating hormone Lactate dehydrogenase Prostatic specific antigen Origins

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You are performing FEME test on cerebrospinal fluid sample. Write your findings if the specimen was sampled from these patients below. a. Viral meningitis b. Bacterial meningitis c. Tuberculous meningitis d. Fungal meningitis

10. Explain tests to investigate renal function. 11. Write your finding of a test done on a urine sample taken from acute renal failure patient. 12. What is the different between creatinine clearance and inulin clearance test? 13. Explain the pathophysiology of PKU. 14. 15. 16. What is the symptom of maternal PKU to the baby? Define hyperglycemia amd hypoglycaemia. What cause these conditions? What are the complications of hyperlipidemia?

17. What test should be asked from biochemistry lab to investigate below diseases: a. b. c. d. Diabetes mellitus G6PD deficiency Phenylketonuria Maple Syrup Urine disorder

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