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  • Xanthogranuloma PPT DS

    Transféré par

    Deba P Sarma
    17 vues9 pages
    A diffuse dermal proliferation of large cells with angulated nuclei, abundant foamy cytoplasm. Multinucleated touton-type giant cells are seen. The lesion is most commonly seen in children, but it can occur at any age.

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    A diffuse dermal proliferation of large cells with angulated nuclei, abundant foamy cytoplasm. Multinucleated touton-type giant cells are seen. The lesion is most commonly seen in children, but it can occur at any age.

    Droits d'auteur :

    Attribution Non-Commercial (BY-NC)
    Signaler comme contenu inapproprié
    17 vues9 pages

    Xanthogranuloma PPT DS

    Transféré par

    Deba P Sarma
    A diffuse dermal proliferation of large cells with angulated nuclei, abundant foamy cytoplasm. Multinucleated touton-type giant cells are seen. The lesion is most commonly seen in children, but it can occur at any age.

    Droits d'auteur :

    Attribution Non-Commercial (BY-NC)
    Signaler comme contenu inapproprié
    sur 9

    Xanthogranuloma

    Deba P Sarma, MD Omaha

    F 18, left shoulder

    CD 68: Positive

    Factor XIIIa: Positive

    Xanthogranuloma
    Intact epidermis with a diffuse dermal proliferation of large cells with angulated nuclei, abundant foamy cytoplasm, and well defined cell borders. The nuclei show inconspicuous nucleoli. Several multinucleated Touton-type giant cells are seen. The cytoplasm of the cells stain for CD 68 and Factor XIIIa, but not with S-100 and CD 1a.
    The lesion is most commonly seen in children, but it can occur at any age.

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