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  • Effect of Phyllanthus Emblica L. (Amla) On Haematological and Biochemical Parameters in Lead Acetate Induced Toxicity in Wistar Rats

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    SJ Iraa
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    The study examined the effects of Phyllanthus emblica L. (Amla) fruit on hematological and biochemical parameters in Wistar rats that were induced with lead acetate toxicity. Thirty rats were divided into three groups, with one group as the control and another given lead acetate mixed with their diet. The third group was given Amla fruit mixed with their diet along with lead acetate. After 60 days of treatment, analysis found that Amla protected the rats' blood, renal, and hepatic systems from the toxic effects of lead, as reflected in hematological and biochemical parameter levels.

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    EFFECT OF PHYLLANTHUS EMBLICA L. (AMLA) ON HAEMATOLOGICAL AND BIOCHEMICAL PARAMETERS IN LEAD ACETATE INDUCED TOXICITY IN WISTAR RATS

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    EFFECT OF PHYLLANTHUS EMBLICA L. (AMLA) ON HAEMATOLOGICAL AND BIOCHEMICAL PARAMETERS IN LEAD ACETATE INDUCED TOXICITY IN WISTAR RATS

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    The study examined the effects of Phyllanthus emblica L. (Amla) fruit on hematological and biochemical parameters in Wistar rats that were induced with lead acetate toxicity. Thirty rats were divided into three groups, with one group as the control and another given lead acetate mixed with their diet. The third group was given Amla fruit mixed with their diet along with lead acetate. After 60 days of treatment, analysis found that Amla protected the rats' blood, renal, and hepatic systems from the toxic effects of lead, as reflected in hematological and biochemical parameter levels.

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    24 vues1 page

    Effect of Phyllanthus Emblica L. (Amla) On Haematological and Biochemical Parameters in Lead Acetate Induced Toxicity in Wistar Rats

    Transféré par

    SJ Iraa
    The study examined the effects of Phyllanthus emblica L. (Amla) fruit on hematological and biochemical parameters in Wistar rats that were induced with lead acetate toxicity. Thirty rats were divided into three groups, with one group as the control and another given lead acetate mixed with their diet. The third group was given Amla fruit mixed with their diet along with lead acetate. After 60 days of treatment, analysis found that Amla protected the rats' blood, renal, and hepatic systems from the toxic effects of lead, as reflected in hematological and biochemical parameter levels.

    Droits d'auteur :

    Attribution Non-Commercial (BY-NC)
    Téléchargez comme PDF, TXT ou lisez en ligne sur Scribd
    Signaler comme contenu inapproprié
    sur 1

    ANIMAL SCIENCE REPORTER

    Animal Science Reporter, January 2010, 4 (1): 22-26

    EFFECT OF PHYLLANTHUS EMBLICA L. (AMLA) ON HAEMATOLOGICAL AND BIOCHEMICAL PARAMETERS IN LEAD ACETATE INDUCED TOXICITY IN WISTAR RATS S.A. Jaiswal1, M.I. Qureshi2 ABSTRACT The ancient Indian texts on ayurveda has extolled the therapeutic properties of the fruits of Phyllanthus emblica L. (Amla). However, there is no reference on its efficacy in heavy metal intoxication. The present study illustrates the effect of the fruits of Phyllanthus emblica L. (Amla) on the haematological and biochemical parameters in lead acetate induced changes in Wistar rats. For this experiment, thirty Wistar rats were divided into three groups of ten each. The rats in group I were fed on balanced diet of rat pellet (control). The rats in Group II were given lead acetate @ 1000 mg/kg feed/ day mixed with the basic diet. The rats in Group III were given pulverized fruit of Phyllanthus emblica L. mixed with the basic rat feed at the concentration of 50 g/kg (w/w) along with lead acetate @ 1000 mg/kg feed daily. The treatments were continued for sixty consecutive days. The analysis of haematological (Haemoglobin concentration and Total Erythrocyte Count) and biochemical (Blood Urea Nitrogen, Serum aspartate transaminase and Serum alanine transaminase) parameters reflected that Phyllanthus emblica L. protected the haematic, renal and hepatic systems of Wistar rats from lead toxicity. KEY WORDS Amla, Blood Urea Nitrogen, Haemoglobin, Lead toxicity, Phyllanthus emblica L., Serum alanine transaminase, Serum aspartate transaminase, Total Erythrocyte Count, Toxicity, Wistar rat __________________________________________________________________________________________________
    Author attribution: 1Programme Assistant (KVK, Hingoli), 2Professor and Head, Department of Veterinary Pharmacology and Toxicology, College of Veterinary and Animal Sciences (MAFS University), Parbhani, Maharashtra, India- 431402. 1Corresponding author: satyamaj@rediffmail.com

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