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TADUS, Kimberly A.

BSN202 Group 8B
Drug Name Generic name: Meropene m Brand name: Merrem Classification Indications & Dosage Contraindications Adverse Effect Nursing Responsibilities

Belongs to the class of carbapene ms. Used in the systemic treatment of infections.

Indications: For serious infections caused by gram-positive or gram-negative organisms

Contraindications: Hypersensitivit y to meropenem or imipenem

Diarrhoea, nausea, vomiting, abdominal pain; headache; constipation; rash, pruritus, uticaria; apnoea; phlebitis, thrombophlebitis, swelling and pain at inj site; disturbances in LFTs (may cause increases in serum transaminases, alkaline phosphatase, lactic dehydrogenase). Rarely: erythema multiforme; eosinophilia, thrombocytopenia, leucopenia, neutropenia; seizures and CNS effects reported in patients with underlying CNS disorders or renal impairment.

Assess patient for previous sensitivity reaction to carbapenems Assess patient for signs and symptoms of infection, including characteristics of wounds, sputum, urine, stool Complete C/S tests before beginning drug therapy Assess for allergic reactions, anaphylaxis Identify urine output Monitor blood studies Monitor electrolytes Assess bowel pattern daily Monitor for bleeding

Precautions: Pregnancy, lactation, renal disease, elderly

TADUS, Kimberly A. BSN202 Group 8B


Potentially Fatal: Anaphylaxis; pseudomembranous colitis; StevensJohnsons sydrome.