Case of bilateral descemetocele with unknown etiology Marishev Y., Drozhyna G., Gajdamaka T., Usov V.

The Filatov Institute of Eye Disease and Tissue Therapy , French Blv.49/51, 65061 Odessa, Ukraine The aim of this report is to present a rare case of bilateral descemetocele. On June 1998 a 27-years woman was admitted to The Filatov Institute with diagnosis symmetrical descemetocele 2.0-2.5mm, placed on inferior 1/3 of the cornea on both eyes. There were no signs of corneal and conjunctival inflammation. The cornea around descemetocele was clear. Visual acuity OU=1.0. All rheumatic tests were negative and our assumption about rheumatic etiology of the process has not been confirmed. On July 1998 biological covering by Puchkovskaya's on the inferior part of the cornea method was performed in right eye. Ten days later the same procedure was done in the left eye. Corneal transplants were detached after 3 weeks. The corneal tissue near limb became thicker, but descemetocele did not change. Before autumn 2000 descemetocele was not increased and visual acuity was :right eye=0.7, left eye=0.85-1.0. On March 2001 descemetocele was increased to 4.0 mm on right and 4.5 mm on left eye. Visual acuity decreased : right eye=0.4 ,left eye=0.6. The keratoplasty was proposed to the patient but she refused. On April 28th 2001 she came with corneal perforation, absent anterior chamber and iris prolapse in OD. Mini penetrating keratoplasty 4.0 mm with simultaneous biological covering by Puchkovskaja was performed. Corneal tissue was sent for hystological test. During 10 days both transplants are fixed. Anterior chamber is middle depth and pupil is round and mobile. Visual acuity OD=0.12 as the half of cornea is covered by biological covering. Possible mechanisms of such disease and treatment will be discussed. Copyright Deutsche Ophthalmologische Gesellschaft, 2001. All rights reserved. Last updated: Sonnabend, 13. August 2005

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