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8.24
E= A*B*C*D
Block 1 has E=+ and Block 2 has E=- each one with 8
observations.
There is no confounding between any main factor or two-way interaction
and block (E) as can be seen in the table below.
A
-1
B
-1
C
-1
D
-1
E(block)
1
AB
1
AC
1
BC
1
1
-1
1
-1
1
-1
1
-1
1
-1
1
-1
1
-1
1
-1
1
1
-1
-1
1
1
-1
-1
1
1
-1
-1
1
1
-1
-1
-1
1
1
1
1
-1
-1
-1
-1
1
1
1
1
-1
-1
-1
-1
-1
-1
-1
1
1
1
1
1
1
1
1
-1
-1
1
-1
1
1
-1
-1
1
1
-1
1
-1
-1
1
-1
-1
1
1
-1
-1
1
1
-1
-1
1
1
-1
-1
1
-1
1
-1
-1
1
-1
1
1
-1
1
-1
-1
1
-1
1
1
-1
-1
-1
-1
1
1
1
1
-1
-1
-1
-1
1
1
8.27
A
-1
1
-1
1
-1
1
-1
1
B
-1
-1
1
1
-1
-1
1
1
C
-1
-1
-1
-1
1
1
1
1
D=AB
1
-1
-1
1
1
-1
-1
1
E=AC
1
-1
1
-1
-1
1
-1
1
F=BC
1
1
-1
-1
-1
-1
1
1
letter
comb
def
af
be
abd
cd
ace
bcf
abcdef
1320
1474
1217
984
765
1338
1325
1275
resp
1156
1164
1201
826
705
1254
1299
976
913
1541
890
936
821
1294
1253
1457