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Drug Study
DRUG ORDER
(Generic
name, PHARMACOLOGI NURSING
INDICATIONS AND ADVERSE EFFECTS DESIRED ACTION
Dosage, C ACTION OF RESPONSIBILITIES
CONTRAINDICATIONS OF THE DRUG ON THE CLIENT
Route, DRUG /PRECAUTIONS
Frequency,
etc.)
1. Paracetamo Antipyretic: Indications CNS: Headache Fever reduction - Monitor liver
l Reduces fever by - Analgesic-antipyretic in CV: Chest pain, function studies;
(250mg/5ml acting directly on patients with aspirin dyspnea, may cause
) 3ml q4h the hypothalamic allergy, hemostatic myocardial hepatic toxicity
for fever heat-regulating disturbances, bleeding damage when at doses
2. Paracetamo center to cause diatheses, upper GI doses of 5–8 g/day >4g/day
l 145mg IV vasodilation and disease, gouty arthritis are ingested daily for - Monitor renal
q4h for T > sweating, which - Arthritis and rheumatic several weeks or function studies;
38oC helps dissipate disorders involving when doses of 4 albumin
heat. musculoskeletal pain (but g/day are ingested indicates
lacks clinically significant for 1 yr nephritis
Analgesic: Site antirheumatic and anti- GI: Hepatic - Monitor blood
and mechanism inflammatory effects) toxicity and studies,
of action unclear - Common cold, flu, other failure, jaundice especially CBC
viral and bacterial GU: Acute kidney and pro-time if
infections with pain and failure, renal tubular patient is on
fever necrosis long-term
- Unlabeled use: Hematologic: therapy.
Prophylactic for children Methemoglobinemia - Check I&O ratio;
receiving DPT vaccination —cyanosis; decreasing
to reduce incidence of hemolytic anemia— output may
fever and pain hematuria, anuria; indicate renal
neutropenia, failure.
Contraindications leucopenia, - Assess for fever
- Contraindicated with pancytopenia, and pain
allergy to acetaminophen. thrombocytopenia, - Assess
- Use cautiously with hypoglycemia hepatotoxicity:
impaired hepatic function, Hypersensitivity: dark urine, clay-
chronic alcoholism, Rash, fever colored stools
pregnancy, lactation. - Assess allergic
reactions: rash,
urticaria
Ibuprofen Inhibits Indications CNS: Headache, Fever reduction - Assess pain
(200mg/5ml) prostaglandin -Relief of signs and dizziness, - Assess
4ml q6h for synthesis by symptoms of rheumatoid somnolence, musculoskeletal
T>/= 39oC decreasing arthritis and insomnia, fatigue, status: ROM
enzyme needed osteoarthritis tiredness, dizziness, before dose and
for biosynthesis; -Relief of mild to tinnitus, 1 hr after.
analgesic, anti- moderate pain ophthalmologic - Monitor liver
inflammatory, -Treatment of primary effects function studies
antipyretic dysmenorrhea CV: Hypertension, - Monitor renal
-Fever reduction palpitations, function studies
-Unlabeled uses: arrhythmia - Monitor blood
Prophylactic for migraine; Dermatologic: studies: CBC,
abortive treatment for Rash, pruritus, Hgb, Hct,
migraine sweating, dry protime if patient
mucous membranes, is on long-term
Contraindications stomatitis therapy
-Contraindicated with GI: Nausea, - Check I&O ratio
allergy to ibuprofen, dyspepsia, GI pain, - Assess
salicylates, or other diarrhea, vomiting, hepatotoxicity
NSAIDs (more common in constipation, - Assess for
patients with rhinitis, flatulence, GI allergic
asthma, chronic urticaria, bleeding reactions, visual
nasal polyps). GU: Dysuria, renal changes and
impairment, ototoxicity
menorrhagia - Identify prior
Hematologic: drug history
Bleeding, platelet - Identify fever:
inhibition with higher length of time in
doses, neutropenia, evidence and
eosinophilia, related
leukopenia, symptoms
pancytopenia,
aplastic anemia, Precautions:
decreased Hgb or - Pregnancy B,
Hct, bone marrow lactation,
depression children,
Respiratory: bleeding
Dyspnea, disorders, GI
hemoptysis, disorders,
pharyngitis, cardiac
bronchospasm, disorders,
rhinitis hypersensitivity
Other: Peripheral to other anti-
edema, inflammatory
anaphylactoid agents, elderly,
reactions to CHF
anaphylactic
shock
Contraindications
- allergy to allopurinol,
blood dyscrasias,
hypersensitivity.