MECHANISM OF DRUG-DRUG NURSING

NAME OF DRUG INDICATION CONTRAINDICATIONS SIDE EFFECTS

ACTION INTERACTION CONSIDERATIONS

Generic Name : Prevention of and - CNS: - Risk of severe - Assess allergy to

Long-acting agonist maintenance - Contraindicated with Headache, bronchospasm if salmeterol;
Salmeterol that binds to beta2 therapy for hypersensitivity to tremor combined with pregnancy, acute
xinafoate receptors in the lungs, bronchospasm in salmeterol, acute - CV: beta-blockers; asthma attack,
causing select patients asthma attack, Tachycardia, use a worsening
Classification: bronchodilation; with worsening or palpitations, cardioselective asthma, lactation
also inhibits the asthma, chronic deteriorating hypertension beta-blocker and
Beta2-selective release of obstructive asthma (life- - Respiratory: monitor patient - Ensure that drug
adrenergic agonist inflammatory pulmonary threatening), acute Worsening of closely if this is not used to
Antasthmatic mediators in the lung, disease, and airway obstruction. asthma, combination is treat acute
blocking swelling and exercise-induced difficulty used asthma or with
inflammation asthma - Use cautiously with breathing, - Potential for worsening or
pregnancy, bronchospasm worsened deteriorating
lactation. hypokalemia and asthma (risk of
ECG death).
abnormalities if - Instruct in the
combined with proper use of
diuretics; monitor diskus.
patient very - Monitor use of
closely inhaler; use of
- Administer with more than 4
extreme caution puffs/day may
to patients being worsen asthma;
treated with obtain evaluation
MAOIs or by physician.
TCAs,or within 2 - Have patients
wk of who experience
discontinuation of exercise-induced
such agents asthma use it 30–
because the 60 min before
action of activity.
salmeterol may - Arrange for
be potentiated by periodic
these agents evaluation of
respiratory
condition.