By: Dan Tamayo

Electrospun Nanofibers are polymer solutions

that are pumped through a syringe

They form an ultrafine fiber that are layered
on top of each other to form a mesh

This mesh can be used to culture and
cultivate cells as a scaffold in tissue
engineering
http://www.jove.com/video/2494/electrospinning-
fundamentals-optimizing-solution-and-apparatus-
parameters 2:23


Used for tissue engineering scaffolding

Can be used to deliver medication







1902- Electrospinning was first discovered by
Marley and Cooley

1934- The apparatus was designed and
patented

1940- The design was perfected and a new
apparatus was patented, this is the apparatus
and technique we use today

Today there are ways that nanofibers can be
electrospun while infused with medication.
While these nanofibers biodegrade, the
medication is evenly released throughout the
body.
Research

Difficult to do
We will be able to make scaffolding out of
materials and chemicals that mimic human
proteins and tissues identically.

The optimal scaffold will be found to make
cells grow, mature and direct cell migration
to the best of their ability.


Meng, Z & Zu, X (2011) Preparation and
characterization of electrospun PLGA/gelatin
nanofibers as a potential drug delivery
system. Colloids and Surfaces B: Biointerfaces. 84
(1) 97-102
Chinwe Nwachukwu, C (2010) Electrospinning
protein nanofibers to control cell
adhesion. University of South Florida Scholar
Commons. 55 (3)
Subbiah, h & Bhat, G (2005) Electrospinning of
nanofibers. Applied Polymer Science. 96 (2) 557-
569