2013 Project Lead The Way,

Inc.
PBS Project 6.1.1 Student Response Sheet Page 1



Project 6.1.1: Student Response Sheet

Introduction
Anna Garcia was only 38 when she died, meaning that at least one of her body
systems was no longer able to support life. The failure of one or more of her body
systems may be the result of injury due to an accident or could be the result of an
illness or a combination of illnesses. Before we can determine which system or
systems failed or what caused the failure which led to her death, we have to learn
more about the human body.

The human body is an amazing machine composed of many interrelated systems
which are in turn composed of cells, tissues, and organs that act independently and
interdependently within the body. No individual component of a human body works
alone. Components of each system in the body affect or interact with every other
system. The body is dependent upon the many interactions between all systems and
structures to maintain homeostasis and health. In this activity you will investigate the
different body systems that make up the human body and explore all of the ways
Annas various illnesses affected each body system, potentially resulting in her
premature death.

Procedure:

1. Look back in your course file and list all of the ways each body system was
impacted by the illness or disease Anna Garcia experienced in her life.
2. Reference Autopsy Reports, Medical Histories and past lab activities to help you
organize this information.
3. Record any evidence that shows how the illness or disease may have been
involved with her untimely death.
4. Be specific about relationships between body systems and illness. You will use
this chart to help construct your final timeline that explains how Anna died.
5. You will need to eventually upload this document to your e-portfolio under Annas
Cause of Death.










2013 Project Lead The Way,

Inc.
PBS Project 6.1.1 Student Response Sheet Page 2





Part II: Annas Illnesses

Illnesses
Effect on
System (if
applicable)


Diabetes Sickle Cell
Anemia
Heart Disease Urinary Tract
Infection
Cardiovascula
r









Allows for
blood glucose
levels to be
regulated,
also nerve
damage can
happen.
Damage to
circulation
and nerves in
the legs or
feet can often
lead to the
increased risk
of foot ulcers
and may need
amputation.
















Sickle cells
stick together
on the walls
of the blood
vessels which
causes them
to narrow and
leads to
blockages
and then
slows down
the blood
flow. This
leads to many
swellings on
the limbs of
the body.
Clumps or
clots can also
lead to
stroke.
Heart disease
interferes
with the
cardiovascula
r system
because it
changes the
blood flow
due to
irregular
beating.
A urinary
tract infection
could
possibly
spread
through the
blood flow to
the rest of the
body. Also
urinary tract
infections can
lead to kidney
stones. Also
she is more
likely to have
this infection
because she
has diabetes.



2013 Project Lead The Way,

Inc.
PBS Project 6.1.1 Student Response Sheet Page 3




Digestive









Gastroperisis.
this causes
delays in
emptying the
stomach
which
changes
blood glucose
levels
Bilirubin
gallstones -
sickle cells die
in 20 days;
liver breaks
down the
bilirubin; extra
bilirubin can
become a
gallstone in the
gallbladder


(bilirubin forms
bile)





Low HDL and
high LDL are
due to poor
dieting and
poor living
habits
UTI infections
increase the
risk for
bacteria
growing in
the digestive
system.
Bacteria such
as ecoli ect.
Immune









when an
infection or
disease gets
triggered the
T lymphocyte
starts to
target and
destroy the
insulin.
bacterial
infections
also attack
the immune
system
weakend
immune
system is due
to many
difficulities
within the
body. sickle
cell reduces
the bloodflow
because they
clot. this
makes the
body more
increased risk
for infection
Increased
production of
lymphocytes
(B & T cells)
and antibodies
against the
bacteria;
Inflammatory
response (may
increase
additional UTI
and/or damage
to urinary tract
structures.
Nervous







high levels of
blood glucose
levels leads
to nerve
damage/
neuropathy.
this is more
common for
swelling of
limbs
lack of
bloodflow
and oxygen
blockadges
cause nerve
damage and
other
problems
problems can
lead to UTI
infections



2013 Project Lead The Way,

Inc.
PBS Project 6.1.1 Student Response Sheet Page 4



people with
diabetes
Respiratory









rapid
breathing can
be a problem
for people
with diabetes
becuase of
shortning of
breath, this
causes
ketoacidosis
and high
blood glucose
levels
Acute chest
syndrome:
abnormalities
in breathing
heavily
causes
shortnesses
of breath
Lack of blood
flow to the
lungs causes
lack of blood
flow to the
rest of the
body also and
causes
organs to die.
spesis
Urinary









Elevated high
blood glucose
levels
increase risk
of bacterial
growth which
increases the
risk of a
urinary tract
infection.
Urinary tract
infections are
more
common for
people with
sickle cell
diesease
organ
damage and
innfacevtive
fuctioning
Bladder
infections are
common and
can be treated
and not
harmful if
treated right
away, but if
you hold off
on treating it,
it can spread
to your
kidneys and
cause a
kidney
infection or
kidney
stones.

Sources Used: