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LATIHAN BELAJAR ENDOKRIN ANAK

LATIHAN BELAJAR HIPOTIROIDISME


Satriono, M.Sc., SpA(K)

1.DEFINISI Hipotiroidisme:
1 .Defisiensi hormon !
".Defisiensi hormon tiro#sin
$.Defisiensi hormon $
!.Defisiensi hormon triiodo tironin
%a&a' : E
".(en)e'a' ter'an)a# Hipotiroidisme Kon*enita+ den*an *e,a+a str-ma.
A.Dis*enesis .Atireosis tiroid.
/.D)shormo*enesis
0.1'at2o'atan (K%, 3oitro*en)
D.h)roid HormonE 4nresponsi5eness
E.Defisisensi SH
%a&a' : A
$. Simptom HI(1I61IDISME /A7I se'a*ai 'eri#-t, KE04A8I
A.1'stipasi
/.Ma+as menete# (Min-m s-s-)
0./a)i hiper a#tif
D.I#ter-s neonator-m (ro+on*at-s
E.Hipotermi
%a&a' : 0
!.Si*ns (3e,a+a K+ini#) HI(1I61IDISME /A7I )an* dise'a'#an tiroid e#topi#:
1.Hipotoni
". Distenden A'domen
$.Hernia -m'i+i#as+is
!.3ondo#
%a&a' : E
9.Si*ns (3e,a+a K+ini#) HI(1I61IDISME /A7I se'a*ai 'eri#-t, KE04A8I
A.S)ndne) 8ine
/.3ondo#
0. %ant-n* : Kardiome*a+i
D.%ant-n*: /isin* :
E. Fontane+a post ter'-#a &a#t- +ahir
%a&a' : A
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LATIHAN BELAJAR ENDOKRIN ANAK
;. Simtom HI(1I61IDISME ANAK
1.(ert-m'-han Menta+ ter+am'at
".(ert-m'-han Fisi# ter+am'at
$.(ert-m'-han Dentisi er+am'at
!.(ert-m'-han (-'ertas ter+am'at
%a&a' : A
<.Si*ns (3e,a+a K+ini#) HI(1I61IDISME ANAK
1.3oiter 'isa ada . tida#
".K-+it: (-cat
$.K-+it: e'a+,
!.K-+it:Karotinemi#,
%a&a' : E
=. (emeri#saan > 6a) pada HI(1I61IDISME ANAK :
1. dis*enesis epifisis (?i+#in)
". i+iac inde@ menin*#at
$. /one A*e ter+am'at
!. s-d-t aseta'-+-m men-r-n
%a&a' : /
A. (emeri#saan )an* ta# ter+a+- per+- di#er,a#an pada hipotiroidisme 'a)i.ana#:
A.Scannin* iroid
/.EE3
0.EK3
D.EM3 (E+ectrom)o*ram)
E. /M6
%a&a' : E
1B.Dia*nosti# HI(1I61IDISME :
1.Hiper#o+estero+emia
".H' rendah
$. /one A*e ter+am'at
!.SH sensitif menin*#at
%a&a' : E
11.Dia*nosti# HI(1I61IDISME :
1.Hipotoni
".I#ter-s neonator-m (ro+on*at-s
$. /one A*e ter+am'at
!.EK3 8o& Co+ta*e
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LATIHAN BELAJAR ENDOKRIN ANAK
%a&a' : E
1". Se#aran* -nt-# terapi hipotiroidisme di*-na#an:
1. Sodi-m 8e5o h)ro@in
". h)ra@ (1r*anon)
$. E-th)ro@ (Merc#)
!.h)ranon
%a&a' : A
1$.(en)a#it.Ke+ainan )an* har-s di Dia*nosis /andin* den*an hipotiroidisme:
1.Kondrodistrofi
".D&arfism
$.-rner S)ndrome
!.Do&nDs S)ndrome
%a&a' : E
1!./i+a hipotiroidisme diterapi ter+am'at . tanpa terapi a#an 'era#i'at
1.Kematian o.#.: 1'str-#si sa+-ran nafas
".Kematian o.#.: Infe#si
$.Menta+ 6etardation
!.SeE-e+e Nero+o*i# : in#oordinasi
%a&a' : E
19. 4%I SA6IN3 (S06EENIN3 ES) HI(1I61IDISME K1N3ENIA8 (ADA
NE1NA4S dipa#ai :
A.6H
/.SH
0./3
D.$
E.!
%a&a' : /
1;. Ha+2ha+ )an* 'enar men*enai seoran* ana# +a#i2+a#i )an* didia*nosis hipotiroidisme
pada -m-r $ tah-n #em-dian mendapat terapi hormone tiro#sin ade#-at se+ama ! tah-n ,
#eadaann)a pada -m-r < tah-n:
1. Hei*ht A*e (4m-r (era&a#an) F < tah-n.
". IG rendah .
$. /one A*e (4sia t-+an*) F < tah-n
!. /radi#ardi
1<..K8ASIFIKASI HI(1I61IDISME 'erdasar#an ter,adin)a
A.. HI(1I61IDISME K1N3ENIA8 H HI(1I61DISME DIDA(A
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LATIHAN BELAJAR ENDOKRIN ANAK
(A0G4I6ED)
/. HI(1I61IDISME ENDEMIK H HI(1I61IDISME S(16ADIK
0. HI(1I61IDISME /A7I H HI(1I61IDISME ANAK
D. HI(1I61IDISME (6IME6,SEK4NDE6,E6IE6
E. HI(1I61IDISME DEN3AN S64MA H HI(1I61IDISME AN(A
S64MA
%a&a' : A
1=.(en)e'a' ter'an)a# Hipotiroidisme didapat (AcE-ired) sporadi#:
A.1perasi
/.A-to imm-ne Disease2 iroidits 8imfositi# Kroni# (HASHIM11)
0.Infe#si
D.1'at2o'atan
E.Defisiensi Iodi-m
%a&a' : /
1A. Simptom HI(1I61IDISME /A7I se'a*ai 'eri#-t, KE04A8I
A.1'stipasi
/.Ma+as menete# (Min-m s-s-)
0.8etar*i 2 ma- tid-r sa,a
D.I#ter-s neonator-m (ro+on*at-s
E.Ma#ro*+osi
%a&a' : E
"B.Si*ns (3e,a+a K+ini#) HI(1I61IDISME /A7I :
1. %ant-n* : Kardiome*a+i
".%ant-n*: /isin* :
$. Fontane+a post ter'-#a &a#t- +ahir
!./r-sfie+dIs spot
%a&a' : A
"1.Si*ns (3e,a+a K+ini#) HI(1I61IDISME /A7I se'a*ai 'eri#-t, KE04A8I
A.Hernia -m'i+i#as+is
/.mi#sedema
0.N)sta*m-s
D.Hipotoni
E.M-#a Sem'a'
%a&a' : 0
"". Simtom HI(1I61IDISME ANAK
1.3em-#
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LATIHAN BELAJAR ENDOKRIN ANAK
".Str-ma
$./odoh
!.Cold Intolerance
%a&a' : E
"$.Si*ns (3e,a+a K+ini#) HI(1I61IDISME ANAK
1.K-+it: Din*in,
".Mi#sedema
$.Hipotoni J 1tot 8em'e#
!.A(6 , K(6 J 8am'at
%a&a' : E

"!. (emeri#saan Hormona+ pada HI(1I61IDISME ANAK :
1.Free ! men-r-n
".SH sensitif menin*#at
$.! tota+ men-r-n
!.SH menin*#at
%a&a' : E
"9.4nt-# 'eda#an H (rimer dan H Se#-nder d+a#-#an :
A.4,i SH
/.4,i 6H
0.4,i ha-s
D.EM3
E.TSH Screening Test
%a&a' : /
";.Dia*nosti# HI(1I61IDISME :
1 Free ! men-r-n
".EE3 8o& Co+ta*e
$.EK3 8o& Co+ta*e
!.EM3 (E+ectrom)o*ram) meman,an*
%a&a' : E
"<.Dia*nosti# HI(1I61IDISME :
1.M-#a Sem'a'
".Hipotermi
$.SH sensitif menin*#at
!.EM3 (E+ectrom)o*ram) meman,an*
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LATIHAN BELAJAR ENDOKRIN ANAK
%a&a' : E
"=. (en*o'atan hipotiroidisme #on*enita+:
1.Di+a#-#an -nt-# se-m-r hid-p.
".Men**-na#an o'at e#stra# tiroid.
$.Men**-na#an sodi-m +e5o th)ro@in
!.Men**-na#an o'at steroid.
%a&a' : /
"A.(en)a#it.Ke+ainan )an* har-s di Dia*nosis /andin* den*an hipotiroidisme:
1.A#ondrop+asia
".Hipopit-itarisme
$.-rner S)ndrome
!.Do&nDs S)ndrome
%a&a' : E
$B./i+a hipotiroidisme diterapi ter+am'at . tanpa terapi a#an 'era#i'at
1.Kematian o.#.: 1'str-#si sa+-ran nafas
".Kematian o.#.: Infe#si
$.Menta+ 6etardation
!.SeE-e+e Nero+o*i# : ata#si,spastic
%a&a' : E
$1. 8a'orator) e5idence of c+assic con*enita+ h)poth)roidism in a samp+e of '+ood ta#en
on the third da) of +ife inc+-des
A. e+e5ated SH, +o& !
/. e+e5ated SH, hi*h $
0. +o& SH, +o& !
D. +o& !, hi*h $
E. +o& /3, +o& !
%a&a' : /
$".(en)e'a' Hipotiroidisme Kon*enita+ den*an #adar free ! )an* norma+..
A.Dis*enesis .Atireosis tiroid.
/.D)shormo*enesis
0.1'at2o'atan (K%, 3oitro*en)
D.h)roid HormonE 4nresponsi5eness
E.Defisisensi SH
%a&a' : D
JIHAD IS THE POWER OF MUSLIM Page ;
LATIHAN BELAJAR ENDOKRIN ANAK
LATIHAN BELAJAR HIPOTIROIDISME DD NYA DOWN'S SYNDROME
Satriono, M.Sc., SpA(K)
era#hir diper'ahar-i pada . (a*e -pdated :1B.B=."BB;

1. D1?NDS S7ND61ME (DS)
1.Dip-'+i#asi pertama #a+i tah-n 1=;;
".Dise'-t ,-*a Mon*o+isme
$.Insidens : 12" .1BBB #e+ahiran
!.Etio+o*i di#em-#anan o+eh 8e %e-ne d## tah-n 1A9A
%a&a' : E

". 6IS1MI "1 pada do&nD s)ndrome
1. risomi 6e*-+er A9 K
". rans+o#asi !29 K
$.Mosai# L 2 1 K
!.7an* menem-#an 8e %e-ne d## tah-n 1A9A
%a&a' : E
$.3e,a+a K+ini# DS pada MAA
1.Nista*m-s
".Stra'ism-s
$.Hiperte+orisme
!./r-sfie+dDs Spot

%a&a' : E
!.3am'ar di sampin* ini ini ada+ah :
A.A604S F /4S46
/.811( F 8EN3K4N3
0. 6I 6ADI4S
D.(4SA6AN (?H168)
E. ENED A60H
%a&a' : 0
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LATIHAN BELAJAR ENDOKRIN ANAK
LATIHAN BELAJAR DIABETES MELLITUS PADA ANAK
Satriono, M.Sc., SpA(K)
era#hir diper'ahar-i pada . (a*e -pdated :1B.B=."BB;
Dia'etes me++it-s in 0hi+dren:
1. is a s)ndrome of dist-r'ed ener*) homeostasis ca-sed ') a deficienc) of ins-+in and
res-+tin* in a'norma+ meta'o+ism of car'oh)drate, protein, and fat.
".It is the most common endocrine2meta'o+ic disorder of chi+dhood and ado+escence .
$.important conseE-ences for ph)sica+ and emotiona+ de5e+opment.
! is a s)ndrome of dist-r'ed ener*) homeostasis ca-sed ') ins-+in action and res-+tin*
in a'norma+ meta'o+ism of car'oh)drate, protein, and fat.
%a&a' : E
". 0+assification of Dia'etes Me++it-s in 0hi+dren and Ado+escents for. Ins-+inJ
dependent (IDDM, t)pe I):
'ased on criteria:
1*+-cos-ria
". #eton-ria,
$.random p+asma *+-cose ((3) M"BB m*.d8
!.F(3 N1!B m*.d8 &ith "2hr 5a+-e M1!B m*.d8 d-rin* 13
%a&a' : A
$.Dia'etes me++it-s in 0hi+dren:
1.Ma+es and fema+es are a+most eE-a++) affectedO
".there is no apparent corre+ation &ith socioeconomic stat-s.
$.(ea#s of presentation occ-r at 9J< )r of a*e
!.(ea#s of presentation occ-r at the time of p-'ert)
%a&a' O E
!.he c+assic presentation of dia'etes in chi+dren :
1. po+)-ria,
".po+)dipsia,
$.po+)pha*ia,
!.&ei*ht *ain
%a&a' : A
9. Ketaocidosis in dia'etic chi+dren.
1. appro@imate+) "9K of dia'etic chi+dren
".he ear+) manifestations consist of 5omitin*.
JIHAD IS THE POWER OF MUSLIM Page =
LATIHAN BELAJAR ENDOKRIN ANAK
$.he ear+) manifestations consist of po+)-ria..
!.he ear+) manifestations consist deh)dration.
%a&a' : E
;.0+inica+ si*n In dia'etic chi+dren &ith more pro+on*ed and se5ere cases of
Ketaocidosis:
A.5omitin*.
/. po+)-ria..
0. deh)dration
D.K-ssma-+ respirations
E. Dispnoe dDeffort.
%a&a' : D
<.he dia*nosis of dia'etes me++it-s in chi+dren 'ased on the demonstration of :
1.h)per*+)cemia
".*+-cos-ria &ith or &itho-t #eton-ria.
$.decreased 02peptide
!.increased H'A1c
%a&a' : E
=.the princip+e of treatment of dia'etes me++it-s in chi+dren :
1.ins-+in
".n-trition s-pport
$.e@ercise
!.ed-cation and co-nse+in*
%a&a' : E
A. Ha+2ha+ )an* ada h-'-n*ann)a den*an (613N1SIS DM pada ana#:
1.Serin* terdapat #omp+i#asi Cis-a+ dan mata.
".(-'ertas dapat ter+am'at
$.Di+apor#an adan)a #ematian a#i'at '-n-h diri.
!.in**i 'adan a#hir masih da+am 'atas norma+
%a&a' : A
JIHAD IS THE POWER OF MUSLIM Page A
LATIHAN BELAJAR ENDOKRIN ANAK
LATIHAN BELAJAR STRUMA PADA ANAK.
Satriono, M.Sc., SpA(K)
era#hir diper'ahar-i pada . (a*e -pdated :1B.B=."BB;

3radasi pem'esaran #e+en,ar tiroid men-r-t ?H1:
A.Dera,at 1, 1 A, 1/ , " dan $.
/.Dera,at 1, 1 , " dan $.
0.Dera,at 1, 1 A, 1/ , "
D.Dera,at 1, 1 , ".
E.Dera,at 1, 1 , " .$
%a&a' : D


FI88 IN :
3radasi pem'esaran #e+en,ar tiroid pada s-r5e) 3AKI di Indonesia
Dera,at PP..,PPPP,PPPP,PPPP,PPP,PP...
%a&a' : B, 1A, 1/, ", $
36ADASI MEN464 ?H1 PPP. , PPP.., PPP..
%a&a' : B, 1, "
Str-ma 'isa di*o+on*#an #e da+am :
1PPPPPPPPPPP..
"PPPPPPPPPPP..
$PPPPPPPPPPP..
%a&a' : 1. Menin*#atn)a SH a#i'at 'er#-ran*n)a hormon tiroid
". infi+trasi ata- peradan*an dan neop+asma
$. tirotrop)n receptor stim-+atin* anti'odies (6SA')
(A1FISI1813I E6%ADIN7A S64MA:
1PPPPPPPPPPPPP
"PPPPPPPPPPP
$PPPPPPPP.
%a&a' : 1. Kon*enita+ dan didapat
JIHAD IS THE POWER OF MUSLIM Page 1B
LATIHAN BELAJAR ENDOKRIN ANAK
". endemi# dan sporadi#
$. intratrachea+ dan e#stratrachea+
LATIHAN BELAJAR GANGGUAN PERTUMBUHAN
Satriono, M.Sc., SpA(K)
era#hir diper'ahar-i pada . (a*e -pdated :1B.B=."BB;

(E6A?AKAN (ENDEK
1.(era&a#an pende# ata- short stat-re mer-pa#an s-at- termino+o*i men*enai
pan,an*.tin**i 'adan )an* 'erada di 'a&ah PPP.. ata- PPPP pada #-r5a
pert-m'-han )an* 'er+a#- pada pop-+asi terse'-t.
A. persenti+ #e $ , J$ Standard De5iation
/. persenti+ #e $ , J" Standard De5iation
0. persenti+ #e $ , J1 Standard De5iation
D. persenti+ #e 9 , J" Standard De5iation
E. persenti+ #e 9 , J$ S Standard De5iation
%a&a' : /
".(era&a#an pende# primer . instrinsi#:
A. Hipotiroidisme
/.Sindrom -rner
0 .c-shin* sindrom
D.H)po*onadism
E.6ic#ets
%a&a' : /
Ada 'e'erapa #+asifi#asi pera&a#an pende# )ait- :
a. .......................................
'. ......................................
c. ........................................
d. .....................................
%a&a' : a. Carian norma+
'. primer.intrinsi#
c. se#-nder.e#strinsi#
d. pera&a#an idiopati#

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LATIHAN BELAJAR ENDOKRIN ANAK
'. (era&a#an pende# primer . instrinsi#
1.Sindrom2sindrom )an* dih-'-n*#an den*an #e+ainan #romosom
Q Sindrom -rner
Q Sindrom Do&n
".Sindrom Jsindrom +ain, misa+n)a:
Q Sindrom Noonan
Q Sindrom (rader28a'hart2?i++i
Q Sindrom 6-sse++ Si+5er
Q Sindrme Sec#e+
Q Sindrom H-tchinson 3i+fort
Q Sindrom 0oc#a)ne
c. (era&a#an pende# se#-nder . e@trinsi#
1. (en)a#it . #e+ainan sistemi#
(chronic disease)
Misa+n)a #e+ainan ,ant-n*, par-, +i5er, intestina+, rena+, hemato+o*i, 0NS dan *enera+iRed
inf+ammator) disease, infe#si #roni#, anemia #roni#,ma+a'sor'si
". Ma+n-trisi
$. #e+ainan endo#rin
Q Hipotiroid
Q 3ro&th hormon defisiensi
Q I3F21 defect
Q (se-doh)poparath)roidism
Q he c-shin* sindrom
Q Ma-riac s)ndrome (#arena re*-+asi *+-#osa )an* ,e+e# pada pasien dia'etes me++it-s)
Q H)po*onadism
Q 6ic#ets
LATIHAN BELAJAR KELAINAN GENITALIA PADA ANAK.
Satriono, M.Sc., SpA(K)
era#hir diper'ahar-i pada . (a*e -pdated :1B.B=."BB;

1.Micropenis (A*e 1 J 11 )r) if +en*th of the penis :
A. N 1 cm
/. N " cm
0.N ",9 cm
D. N $ cm
E N ! cm
%a&a' : D
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LATIHAN BELAJAR ENDOKRIN ANAK
S1A8 FI88 IN
Hormona+ treatment for cr)ptorchidism ') -sin* :.....................................
or .................................
%a&a' : H03 ata- 8H26H.
S1A8 /ENA6.SA8AH
Some 'e+ie5e that preoperati5e treatment &ith h03 faci+itates s-r*er).
%A?A/: A./ENA6
/.SA8AH
%a&a' : A
LATIHAN BELAJAR HIPERPLASIA ADRENAL KONGENITAL.
Satriono, M.Sc., SpA(K)
era#hir diper'ahar-i pada . (a*e -pdated :1B.B=."BB;

1. (en)e'a' 0on*enita+ Adrena+ H)perp+asia ter'an)a#:
A.Deficienc) of "12h)dro@)+ase
/.E@cess of "12h)dro@)+ase
0. risom) "1
D.risom) 1=
E. Defisiensi 3n6H
%a&a' : A


". (ada pemeri#saan #romosome #eti*a 'a)i di atas !;, >>.
Keti*a 'a)i ts' ada+ah: PPPPPP. Den*an PPPPPPPPPP
A. ma+e pse-dohemaphrodites , 4ntreated con*enita+ adrena+ h)perp+asia
/. fema+e pse-dohemaphrodites , 4ntreated con*enita+ adrena+ h)perp+asia
0. ma+e pse-dohemaphrodites , cr)ptorchisim
D. hemaphrodites , 4ntreated con*enita+ adrena+ h)perp+asia
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LATIHAN BELAJAR ENDOKRIN ANAK
E. hermaphrodites
%a&a' : /
FI88 IN
?hen the adreno*enita+ s)ndrome is associated &ith con*enita+ adrena+ h)perp+asia, it is
ca-sed ') a fami+) of PPPPPPPPPP.. disorders of adrena+ steroido*enesis
+eadin* to a deficienc) of PPPPPPP.. .
he deficienc) of cortiso+ res-+ts in increased secretion of PPPPPP., &hich +eads in
t-rn to adrenocortica+ h)perp+asia and o5erprod-ction of intermediar) meta'o+ites.
Se5ere and mi+d forms of these disorders, ca-sed ') 5ariations in the se5erit) of the
*enetic m-tations, ha5e 'een reported.
%a&a' : a-tosoma+ recessi5e, cortiso+, corticotropin
0on*enita+ Adrena+ H)perp+asia
Deficienc) of PPPPPPPPPPPP for A9K of affected patients.
%a&a' : "12h)dro@)+ase
JIHAD IS THE POWER OF MUSLIM Page 1!