DOPAMINE, the constants are

single dose = 13.3 (translates to 200/250 or 400/500)

double dose = 26.6 (translates to 400/250 or 800/500)

DOBUTAMINE, the constants are
single dose = 16.6 (translates to 250/250 or 500/500)
double dose = 33.3 (translates to 500/250 or 1000/500)

DOSAGE x WT

constant

Computation of double-dose dopamine:
Pt wt. 176lbs. doctor ordered 5mcg/kg/MIN. available is 400/250 DOPAMINE in
D5 water. how many ml/hr to give?

(5 mcg / kg min) x (80 kg) x
(250 ml / 400 mg) x (1 mg / 1000 mcg) x (60 min / 1 hr)

The short-cut it is:

(5 mcg / kg min) x (80 kg)
________________________________
26.6 <-- (this is the RECIPROCAL of 0.0375)




Infuse Dobutamine 500 mg in 250 ml D5W at 5 mcg/kg/min using microdrip tubing.
The client weighs 182 lbs. Determine the ml/hr and the gtts/min.

Given:
500mg/250ml (this is double-dose dobu)
5 mcg/kg/min
182 lbs
60gtts/ml <------- microdrip

Find:ml/hr
182 lbs x (1kg/2.2lbs) = 82.7kg
(5 mcg/kg min) x (82.7kg) = 413.5 mcg/min
413.5 mcg/min x 1mg/1000mcg = .4135 mg/min
.4135 mg/min x 250ml/500mg
since were looking for ML/HR

= 0.20675ml/min
= 0.20675ml/min x (60 min / 1 hr) = 12.4 ml/hr

Using the short-cut: 33.3 is constant for double dose dobutamine...

5mcg/kg-min x 82.7kg divide by 33.3 = 12.41 ml/hr