Solubility of paracetamol in water

Ref:

Granberg, R.; Rasmuson, A., Solubility of paracetamol in pure solvents

J. Chem. Eng. Data, 1999, 44, 1391-1395
Molecular weight
M(P)
151.17
M(H2O)
18.02

Melting data of paracetamol

Melting point
170.45 C
Melting enthalpy
27.0
kJ/mol

Temperature
[C]

Solubility
[g P/kg water]

Solubility
[mass%]

Solubility
[mol/mol tot]

0
5
10
15
20
25

7.21
8.21
9.44
10.97
12.78
14.90

0.716%
0.814%
0.935%
1.085%
1.262%
1.468%

0.0008587195
0.0009777043
0.0011240166
0.0013059551
0.001521104
0.0017729838

Solubility of paracetamol in water

16

14

Solubility [g paracetamol/kg water]

12

10

0
-5

10

15

Temperature [C]

20

25

30