Posted by Artikel Bahasa Inggris at Sunday, October 28, 2012

Acyclovir Pharmacology and Indication

Artikel-bahasainggris.blogspot.com - Acyclovir is acyclic purine nucleoside analogue active

against herpes simplex virus, varicella zoster, Epstein-Barr virus and cytomegalovirus. In
the cell, undergo phosphorylation acyclovir acyclovir triphosphate into an active form that
inhibit the herpes simplex virus DNA polymerase and viral DNA replication, thereby
preventing viral DNA synthesis without affecting normal cell processes.
Acyclovir Pharmacology
Acyclovir is an antiviral agent highly active in vitro against herpes simplex virus (HSV) types
I and II, and varicella zoster virus. Upon entry into the infected cell, the phosphorylated
form of the active compound Acyclovir Acyclovir trifosfate. The initial phase of the process
depends on the enzyme thymidine kinase viral-coded. Acyclovir trifosfate act as inhibitors
and as a false substrate for the herpes-specified DNA polymerase which prevents viral DNA
synthesis without affecting normal cellular processes.
Treatment of herpes simplex virus infections of the skin and mucous membranes including
initial and recurrent genital herpes / recurrent, herpes zoster (shingles / shingles /
shingles). Preventing recurrence of herpes simplex infections in patients with strong
immune systems. Preventing herpes simplex infection in patients with poor immune
systems.
Another acyclovir pharmacology is a treatment of herpes simplex virus infections of the skin
and mucous membranes including initial and recurrent genital herpes / recurrent, herpes
zoster (shingles / shingles / shingles); preventing recurrence of herpes simplex infections in
patients with strong immune systems; preventing herpes simplex infection in patients with
poor immune systems.
Acyclovir Indication
Acyclovir indication such as treatment of herpes simplex virus on the skin and mucus
membranes, including initial and recurrent genital herpes; treatment of herpes zoster and
varicella infections; treatment of infections caused by the herpes simplex of the skin and
mucous membranes including initial and recurrent genital herpes, herpes simplex infection
prevention in immuno-compromised patients; treatment of herpes zoster infection.

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