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OH-
Bicarbonate
+ HCO3water
H+
Acidosis
Alkalosis
H+ = CO2 = HCO3-
H+ = CO2 = HCO3-
Expected
Compensations
Increased
breathing
rate
Increased
absorption and
creation of
bicarbonate
Expected
Compensations
Failures
to Compensate
If breathing
is slow =
increased CO2 =
Respiratory
Acidosis
If HCO3- is
low =
Metabolic
Acidosis
Failures
to Compensate
100 90 80
70
Decreased
breathing
rate
Secretion\excretion
of bicarbonate
by kidneys
If HCO3- is
high =
Metabolic
Alkalosis
If breathing
is rapid =
decreased CO2 =
Respiratory
Alkalosis
60
56
20
70
60
50
52
pH < 7.35
pH > 7.45
Acidosis
Alkalosis
pH
HCO3 <
20 mmol/L
CO2 =
CO2 <
35 mmHg
HCO3-
HCO3 >
27 mmol/L
44
Patient would
breathe slowly
Metabolic
Acidosis
Patient would
breathe rapidly
Respiratory
Alkalosis
Metabolic
Alkalosis
Patient would
breathe rapidly
Patient would
breathe slowly
Metabolic
Alkalosis
Chronic
Respiratory
Acidosis
40
30
25
36
32
28
Acute R
e
spirato
24
20
ry Acid
osis
20
Normal
Chronic
Respiratory
Alkalosis
16
12
8
Respiratory
Acidosis
35
PC
O
2 (m
mH
g)
48
40
Acute
Respiratory
Alkalosis
15
10
Hg)
(mm
O
2
C
P
Metabolic
Acidosis
4
0
7.0
7.1
7.2
7.3
7.4
7.5
Arterial blood pH
7.6
7.7
7.8