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29 (CM36 )
Implantation()
1. implantation
endometrium()
2. trophoblast endometrium
syncytiotrophoblast() inner layer
cytotrophoblast()
3. syncytiotrophoblast hCG corpus luteum
hCG pregnancy
syncytotrophoblast hCG stroma cell
glycogen mucus
Ectoderm neural
plate() Ectoderm Neuroectoderm(
)
1.
2.
3.
ant. neuropore 25
post. neuropore 27
4.
5.
1.
Intermediate mesoderm()
urogenital structures()
(1) pronephros()
(2) mesonephros()
metanephros()
(3)
(4)
2. Paraxial mesoderm()
(1) neural crest
(2) occipital somite ()
20 42
somite
3. Lateral plate mesoderm()
(1)
a).(parietal mesoderm layer)
(Somite)
1.
(sclerotome)
2.
dorsolateral
3.
dorsomedial
4.
sclerotomemyotomedermatome
Vasculogenesis()
(blood island)
1.
2.
yolk sac()
3.
yolk sac
() gut()
foregut midgut hindgut
2.
3.
4.
head fold
Lung bud
2.
3.
4.
(1) (foregut)
(2) (midgut)
(3) (hindgut)
. 38 premature()
postmature()
Monthly changes ()
1.
3.
5. external genitalia()
1.
lanugo hair()
2.
1.
1.
6-7 surfactant
1.
2. CRL 36cm, CHL 50cm 3000~3400g
3.
1. embryonic pole()
2. abembryonic pole()
chorion laeve() smooth chorion
6
3.
4. placenta()
5. amniochorionic membrane()
2. intestine loop --
physiological umbilical hernia() 10
3.
umbilical cord ()
7
Skeletal System()
1. paraxial mesoderm() lateral plate mesoderm(
) somatic layer() neural crest()
2. somitesomite
neural tube notochord()
3.
a. intramembranous ossification() bone
spicules()Ex:
b. endochondral ossification()
Ex:
Sutures()
Skull()neurocarnium() viscerocranium()
neurocarnium
1. membranous part() flat bones neural
crest paraxial mesoderm()
2. cartilaginous part()
neural crest()sella turcica() paraxial mesoderm
viscerocranium():
1. 1 2 pharyngeal arches()
2. 1 pharyngeal arch
a.
b.
Limbs():
8
4 ()()
() mesenchymal core---
limbs skeleton connective tissue
apical ectodermal ridge (AER)AER
AER
6 handplates() footplates()
()(
) arms forarms
7 90 90
8 endochondral ossification
handplates footplates AER
(
)()
Vertebral Column()
somites() sclerotomes(
) notochord()
notochord
sclerotomes cephalic() sclerotomes caudal()
sclerotomes
notochord skeletal cell intervertebral
disc() notochord intervertebral disc
somite somite
9
sternum ()
Muscular system
mesodermal layer
1.dorsolateral
2.dorsomedial
sclerotome cells
myotome
1.epimere
10
2.hypomere
Body Cavity
Formation of the Intraembryonic Cavity
1.
somatic mesoderm layesplanchnic
mesoderm layer
2. intraembryonic coelom body
cavity
3. dorsal mesentery
4. folding
Serous Membranes
serous membranes---
(parietal layer)(visceral layer)
2. pleuropericardial foldsfold
pleuropericardial membrane
pleural cavity pericardial cavitypleuropericardial
membrane fibrous pericardium
Formation of the Diaphragm()
Diaphragm
(1) Septum transversum
(2) Pleuroperitoneal folds
(3) Dosal mesentery()
(4) myoblasts
Phrenic nerves()( C1C2C3C4 )
Diaphragm ? Septum transversum
C4C5
T8~T12 Phrenic nerve
12
Pharyngeal arch
1. 5 Pharyngeal arches Pharyngeal
arch endoderm ectoderm mesenchymal
tissuemesenchymal tissue mesodermal cell
neural crest cells
2. Pharyngeal arches mesodermal cell
neural crest cells
3. 6 Pharyngeal arches 5 Pharyngeal arch
V.
&
Meckel
VII.
IX.
46
X.
()
&
()
13
Pharyngeal pouch
1st pharyngeal pouch tubotympanic recess
1. tubotympanic recess
2. tubotympanic recess auditory tube
2nd pharyngeal pouch
palatine tonsil
Palatine tonsil
3rd pharyngeal pouch dorsal wing ventral wing
1. dorsal wing inferior parathyroid
2. ventral wing thymus
4th pharyngeal pouch superior parathyroid
5th pharyngeal pouch
ultimobranchial body C
cells calcitonin
Pharyngeal clefts
1. pharyngeal clefts pharyngeal cleft
Tongue
Thyroid gland
hyroid gland 2/3 1/3 (
)
pharyngeal gut
respiratory diverticulum
respiratory diverticulum
tracheoesophageal ridges tracheoesophageal ridges
tracheoesophageal septum
Respiratory diverticulum lung buds
Larynx
2. bronchopulmonary segments
Bronchopulmonary segments
respiratory bronchioles
(type I alveolar epithelial cells)
type II alveolar epithelial
cells surfactant
type II alveolar epithelial cells
surfactant
Digestive System
primitive
gut
primitive gut
1.
2.
3.
4. hindgut
splanchnic mesoderm
Mesenteries
1.
ventral mesentery falcifrom ligament
lesser omentum
Stomach
1
dilation rotation
2 rotation
16
1.
2.
anteroposterior axis 45
3.
lesser curvature
greater curvature
Duodenum
intraperitoneal organ
Extraperitoneal organ retroperitoneal position
Pancreas
1 foregut duodenum endodermal lining
2 :
1.dorsal pancreatic bud
2.ventral pancreatic bud
Midgut
1.
cephalic limb of primary intestinal
loop caudal limb of primary intestinal loop superior mesenteric artery
90mesonephron
17
Hindgut
1 Cloaca cloacal mambrane
2 urorectal septum cloacal mambrane
perineal body perineal body
allantois hindgut
3 Perineal body urogenital membrane anal
membrane
4 Anal membrane anal canal
1.
2.
pectinate line
**
18