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Endocrine System
Hormones
AP Biology
2004-2005
endocrine system
secrete chemical signals directly into
blood
slow, long-lasting response
nervous system
system of neurons, central
nerve system
fast, short-lasting response
AP Biology
2004-2005
Neurotransmitter
Hormone
carried
by blood
Receptor
proteins
AP Biology
Target cell
2004-2005
AP Biology
2004-2005
Steroid
S hormone
2
4
S
Nucleus
AP Biology
5 Protein
Hormone-receptor complex
enters nucleus & binds to
DNA, causing gene
transcription
Protein is
produced.
2004-2005
3
mRNA
1
Protein
carrier
Plasma membrane
1 Steroid hormone (S)
2
DNA
Blood plasma
Signal molecule
Cell surface
receptor
enzyme
membrane
trigger secondary
messenger pathway
signal transduction
multi-step cascade
activate cellular response
cAMP
G protein
ATP
Target
protein
Nucleus
AP Biology
Cytoplasm
2004-2005
Protein
hormone
activates
enzyme
G protein
cAMP
Receptor
protein
ATP
GTP
Cytoplasm
AP Biology
activates
enzyme
activates
enzyme
Produces an action
protein
messenger
cascade
2004-2005
Epinephrine
activates
G protein
Receptor
protein
adrenal gland
adenylyl cyclase
cAMP
ATP
activates
protein kinase-A
GTP
Cytoplasm
AP Biology
activates
phosphorylase
Glycogen
released
to blood
Glucose
2004-2005
Receptor protein
Not yet
activated
2 Amplification
4 Amplification
3
GTP
cAMP
5
G protein
Protein kinase
6 Amplification
Amplification!
AP Biology
Enzyme
7 Amplification
Enzymatic product
2004-2005
AP Biology
2004-2005
Hypothalamus
on
rm
tin
ac
)
RL
Gr
ow
th
(P
ho
ol
Pr
(G
H
Thyroid-stimulating
Antidiuretic
Hormone
Posterior
hormone
(TSH)
pituitary (ADH)
Thyroid gland
pic
o
Anterior
r
t
o
c
i
Kidney
t
r
)
o
H
c
pituitary
M
T
o
n
C
tubules
el
Ox
Adremone (A
a
yt
no
hor
cy ocin
Muscles
te
-s
of uterus
tim
Gonadotropic
ul
at
hormones:
in
Adrenal
g
Follicleho
cortex
stimulating
rm
(M on
hormone (FSH)
SH e
& luteinizing
)
hormone (LH)
Melanocyte
in amphibian
Bone
and muscle
AP Biology
Testis
Ovary
Mammary
glands
in mammals
2004-2005
stimulus triggers
control mechanism
that inhibits further
change
body temperature
sugar metabolism
Positive feedback
AP Biology
stimulus triggers
control mechanism
that amplifies effect
lactation
labor contractions
Hypothalamus
Releasing hormones
(TRH, CRH, GnRH)
Anterior pituitary
Inhibition
Tropic hormones
(TSH, ACTH, FSH, LH)
Target glands
(thyroid, adrenal cortex, gonads)
Hormones
2004-2005