Biology 303

Instructor:
Fundamental Genetics, Sect. 003
Dr. Alan S. Waldman
Spring, 2015
CLS rm 309 (7-8405)
MWF 10:50- 11:40AM
Office Hours: MW 2:30-3:30
Room: CLS 005
(or by appointment)
Course Website on Blackboard
awaldman@biol.sc.edu
------------------------------------------------------------------------------------------------------Required Text: Klug, Cummings, Spencer, and Palladino, Concepts of Genetics, Tenth Edition,
Pearson Publishers.
------------------------------------------------------------------------------------------------------Tentative Course Schedule
Date:

Topic:

Chapter:

1/12
1/14
1/16
1/19
1/21
1/23
1/26
1/28
1/30
2/2
2/4
2/6
2/9
2/11
2/13
2/16
2/18
2/20
2/23
2/25
2/27
3/2
3/4
3/6
3/9-3/13
3/16
3/18
3/20
3/23
3/25
3/27
3/30
4/1
4/3
4/6
4/8

Course overview
Mitosis & Meiosis
Mendelian Genetics
Martin Luther King Dayno class
Mendelian Genetics
Mendelian Genetics
Extension of Mendelian Genetics
Extension of Mendelian Genetics
Think Genetics Its Friday (TGIF)*
Chromosome Mapping in Eukaryotes
Chromosome Mapping in Eukaryotes
Chromosome Mapping in Eukaryotes
Chromosome Mapping in Eukaryotes/Sex Determination 5,7
EXAM I
Sex Determination and Sex Chromosomes
Chromosome Mutations: Variation in Number and Arrangement
Chromosome Mutations: Variation in Number and Arrangement
Extranuclear Inheritance
DNA Structure and Analysis
DNA Structure and Analysis
TGIF
DNA Replication
DNA Organization in Chromosomes
Gene Mutation, DNA Repair, and Transposition
Spring Break!!
Gene Mutation, DNA Repair, and Transposition
Gene Mutation, DNA Repair, and Transposition
The Genetic Code and Transcription
Regulation of Gene Expression in Prokaryotes
EXAM II
TGIF
Regulation of Gene Expression in Eukaryotes
Regulation of Gene Expression in Eukaryotes
Regulation of Gene Expression in Eukaryotes
Cancer and Regulation of the Cell Cycle
Cancer and Regulation of the Cell Cycle

2
3
3
3
4
4
5
5
5
7
8
8
9
10
10
11
12
15
15
15
13
16
17
17
17
19
19

4/10
4/13
4/15
4/17
4/20
4/22
4/24
4/27

Recombinant DNA Technology

Genomics, Bioinformatics, and Proteomics
Genomics, Bioinformatics, and Proteomics
EXAM III
Applications and Ethics of Genetic Engineering and
Biotechnology
Applications and Ethics of Genetic Engineering and
Biotechnology
Applications and Ethics of Genetic Engineering and
Biotechnology
Catch-up/review

20
21
21
22
22
22

----------------------------------------------------------------------------------5/4
FINAL EXAM, 9:00 AM (Comprehensive)
----------------------------------------------------------------------------------*

TGIF refers to special reading or other exercises that will be assigned.

Learning Outcomes
By the end of the term, successful students will have gained a fundamental knowledge of both
classical (Mendelian) and molecular genetics. More specifically:
Students will understand how genetic traits are transmitted.

Students will learn how to predict the expected types and probabilities of particular
genotypes and phenotypes among offspring of genetic crosses.

Students will understand DNA structure and how it may be altered by mutation.

Students will gain skills needed to perform gene mapping.

Students will understand chromosome and genome structure.

Students will understand how gene expression may be regulated.

Students will understand the fundamentals of cancer biology.

Students will gain a comprehension and appreciation of the basics of biotechnology and
related issues.