DEMENTIA

Risk Factors:
Advanced age (early on set-30-65 y.o)
Late on set -65ylo and above)
Genetics

Neurodegeneration

Neural damage
Primarily in cerebral cortex

Formation of Neuritic Plaques

(Deposits of Amyloid Protein,
a protein found in the brain)

Tangled masses of non-functioning neurons

(Neurofibrillary tangles )

Decrease in Brain Size

Alteration of the normal Activity of

Neurotransmitter

Decrease in Production of
Acetylcholine

Decrease in Dopamine
Production

Cognitive Deterioration

Emotional and
Attention Deficit

Decrease in
Functional Ability
(fine movements )

Sisx: - forgetfulness
disorientation to person
places,things and environment

sisx : - depression
- anxiety and agitation
- decrease in attention span

sisx : - unable to
perform ADLs
without assistance
- immobility
(in terminal stage)