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Waktu (jam) Cp (ng/ml) ln Cp

slope
Kel
ln Cp'
Cp'
Cp'-Cp ln Cp'-Cp
0.5
29.3
3.38
-0.37
0.37
4.63 102.34
73.04
4.29
1
42.1
3.74
4.44
85.17
43.07
3.76
1.5
45.7
3.82
4.26
70.88
25.18
3.23
2
44.4
3.79
4.08
58.99
14.59
2.68
3
35.2
3.56
3.71
40.86
5.66
1.73
4
27
3.3
3.34
28.3
1.3
0.26
6
13.6
2.61
2.61
13.57
-0.03 Err:502
8
6.5
1.87
1.87
6.51
0.01
-4.49
12
1.5
0.41
0.4
1.5
0 Err:502

4.5
4
3.5
f(x) = - 0.36x + 4.77
R = 1

3
2.5

Column C
Column C
Linear (Column C)

4 6 8 12

1.5

Linear (4 6 8 12)

1
0.5
0
0

10

12

14

slope
Kabs
-1.06
1.06

Waktu (jamCp (ng/ml)ln cp


slope
Kel
0
0
0.5
29.3
3.38
-0.37
1
42.1
3.74
1.5
45.7
3.82
2
44.4
3.79
3
35.2
3.56
4
27
3.3
6
13.6
2.61
8
6.5
1.87
12
1.5
0.41

AUC]tn-1-tn [AUC]0-tn k[AUC]0-tCp + k[AUC]0


0.37
0.37
0.37
0.37
0.37
0.37
0.37
0.37
0.37

7.33
17.85
21.95
22.53
39.8
31.1
40.6
20.1
16

7.33
25.18
47.13
69.65
109.45
140.55
181.15
201.25
217.25

2.69
9.25
17.31
25.58
40.2
51.63
66.54
73.92
79.8

31.99
51.35
63.01
69.98
75.4
78.63
80.14
80.42
81.3

[AUC]t'-~ [AUC]0-~ k[AUC]0-~ FAbsorpsi


4.08 221.33

81.3
81.3
81.3
81.3
81.3
81.3
81.3
81.3
81.3

0.39
0.63
0.78
0.86
0.93
0.97
0.99
0.99
1

FTA

ln FTA
0.61
-0.5
0.37
-1
0.22
-1.49
0.14
-1.97
0.07
-2.62
0.03
-3.41
0.01
-4.25
0.01
-4.53
0 Err:502

slope
-0.99

ka
0.99