Drug

Name
Genenric
name:
Ceftriazo
ne
Brand
Name:
Forgram
Dosage:
450mg
TIV q12

Classificatio
n
3rd
generati
on
cephalos
porin.

Action

Indication

Consideration

Side Effect

Works by
inhibiting the
mucopeptide
synthesis in
the bacterial
cell wall. The
beta-lactam
moiety of
Ceftriaxone
binds to
carboxypepti
dases,
endopeptida
ses, and
transpeptida
ses in the
bacterial
cytoplasmic
membrane.
These
enzymes are
involved in
cell-wall
synthesis
and cell
division. By
binding to
these
enzymes,

Indicated in
patients with
neurologic
complications,
carditis and
arthritis. It is
also effective
in Gram
negative
infections;
Meningitis,
Gonorrhea. It is
also for Bone
and joint
infections,
Lower
respiratory
tract infections,
middle ear
infection, PID,
Septicemia and
Urinary Tract
infections.

Hypersensiti
ve to
cephalospor
ins,
penicillins
and related
antibiotics.

Pain
Induration
Phlebitis
Rash
Diarrhea
Thrombocy
tosis
Leucopenia
Glossitis
Respiratory
super
infections

Nursing
Consideration
Assess
patients
previous
sensitivityreacti
on to penicillin
or other
cephalosphorin
s.
Assess patient
for signs and
symptoms of
infection before
andduring the
treatment
Obtain C&S
before
beginning drug
therapy
toidentify if
correcttreatme
nt has
beeninitiated.
Report signs
such as
petechiae,
ecchymotic
areas, epistaxis
or other forms
of unexplained

Ceftriaxone
results in the
formation of
of defective
cell walls and
cell death.

bleeding.
Monitor
hematologic,
electrolytes,
renal and
hepatic
function.
Assess for
possibles upper
infection:
itching fever,
malaise,
redness