No

sampel
1
2
3
4
5

kadar
(ppm)
50
100
150
200
250

absorbansi
0.109
0.186
0.254
0.362
0.44

VITAMIN C METODE RENAL

No.
interval
Samp waktu
dt
el
(jam)
1
0-1
1
2
1-1,5
0.5
3
1,5-2
0.5
4
2-2,5
0.5
5
2,5-3
0.5
6
3-3,5
0.5
7
3,5-4
0.5
Y=-0,966x+3,078
k eliminasi = slope t1/2
t1/2 = 0,72 jam
K el = K= -B = 0,966
A =3.078 -B= 0.966

t mid
(jam)
0.5
1.25
1.75
2.25
2.75
3.25
3.75

Vu
(ml)
69
60
60
105
108.2
107.4
106.4

= 0,693/k

Cu
(g/ml
)
-3.165
57.799
29.157
12.562
14.826
15.634
11.992

Du/dt
(mg/ja
m)
-0.218
6.936
3.499
2.638
3.208
3.358
2.552

Du
-0.218
3.468
1.749
1.319
1.604
1.679
1.276

t mid
(jam)
0.5
1.25
1.75
2.25
2.75
3.25
3.75

Ln
Du/dt
1.94
1.25
0.97
1.17
1.21
0.94

VITAMIN C METODE ARE

kode
samp
el

interv
al
waktu
(jam)

Tmid

dt

1
2
3
4

0.5
1.25
1.75
2.25

0-1
1-1,5
1,5-2
2-2,5

1
0.5
0.5
0.5

2.75 2,5-3

0.5

3.25 3-3,5

0.5

3.75 3,5-4

0.5

a
b
r
Kel = -b
T 1/2 eliminasi

3.1146
0.7242
0.9656
0.7242
0.9569
18

Vu
(ml)

69
60
60
105
108.
2
107.
4
106.
4

Cu
(g/ml)

Du
(mg)

Du
kum

Du-Du
kum

-3.165
57.799
29.157
12.562

0
-0.22
3.47
1.75
1.32

-0.22
3.25
5.00
6.32

11.31
7.85
6.10
4.78

0.5
1.25
1.75
2.25

2.426038122
2.060007493
1.807732649
1.563938035

14.826

1.60

8.14

2.96

2.75

1.083512323

15.634

1.68

9.82

1.28

3.25

0.243690059

11.992

1.28

11.10

0.00

3.75 -

T mid

Ln (Du - Du
kum)

VITAMIN B1 RENAL
No.
Samp
el

interva
l
waktu
(jam)

0-1

2
3
4
5

dt

Vu
(ml)

0.5

81

1-1,5
1,5-2
2-2,5

0.5
0.5
0.5

1.25
1.75
2.25

27
36
82

2,5-3

0.5

2.75

88

0.5
0.5

3.25
3.75

85
72

6
3-3,5
7
3,5-4
Y=-0.7514x +
5.4384
r=
0.7526
k eliminasi =
slope
K el = K= -B =
0,7514
5.43
A=
84
0.75
-B=
14
t1/2 = 0,693/k
t1/2 =

t mid
(jam)

0.92 jam

Cu
(ug/ml
)

Du/dt
(mg/ja
m)

Du

-58.09
202.8
5
56.67
98.09
146.1
9
150.9
5
84.28

-4.705

-4.705

0.5

10.954
4.080
16.087

5.477
2.040
8.043
12.86
5
12.83
1
6.068

1.25
1.75
2.25

2.39
1.41
2.78

2.75

3.25

3.25
3.75

3.24
2.50

25.729
25.662
12.136

t mid
(jam)

Ln
Du/dt

VITAMIN B1 ARE
kode
samp
el

interv
al
waktu
(jam)

dt

Vu
(ml)

Cu
(g/ml)

Du
(mg)

Du
kum

Du-Du
kum

81

-58.09

0
-4.71

2 1-1,5

0.5

27

202.85

5.48

0.77

46.55

3 1,5-2

0.5

36

56.67

2.04

2.81

44.51

4 2-2,5

0.5

82

98.09

8.04

10.86

36.47

5 2,5-3

0.5

88

146.19

12.86

28.43

18.90

6 3-3,5

0.5

85

150.95

12.83

41.26

6.07

7 3,5-4

0.5

72

84.28

6.07

47.32

0.00

1 0-1

a
b

4.0105
0.1267

0,9842

Kel = -b
T 1/2
eliminasi

0.1267
5.4696
13

-4.71

52.03

Tmi
d

Ln (Du Du kum)

0.5 3.951808
1.2
5 3.840579
1.7
5 3.795766
2.2
5
3.59646
2.7
5 2.939104
3.2
5 1.803055
3.7
5 -

VITAMIN B6 RENAL
No.
Samp
el

interva
l
waktu
(jam)

0-1

t mid
(jam)

dt

Vu
(ml)

0.5

34

1-1,5

0.5

1.25

40

1,5-2

0.5

1.75

139

2-2,5

0.5

2.25

175

2,5-3

0.5

2.75

179

3-3,5

0.5

3.25

169

0.5

3.75

188

7
3,5-4
Y=-0.3296x +
5.588
r=
0.9913
k eliminasi =
slope
K el = K= -B =
0.3296

Cu
(ug/ml
)

Du/dt
(mg/ja
m)

-9.867
1841.
47

-0.335
147.31
8
149.23
0
130.01
5
105.29
9

536.8
371.4
7
294.1
3
273.4
7
365.4
7

92.433
137.41
7

Du
-0.335
73.65
9
74.61
5
65.00
7
52.64
9
46.21
6
68.70
8

t mid
(jam)

Ln
Du/dt

0.5
1.25

4.99

1.75

5.01

2.25

4.87

2.75

4.66

3.25

4.53

3.75

4.92

5.58
8
0.32
96

A=
-B=

t1/2 = 0,693/k
t1/2 =

kode
sampe
l

2.10

Tmi
d

interv
al
waktu
(jam)

dt

Vu
(ml)

Cu
(g/ml)

Du
(mg)

Du
kum

Du-Du
kum

-0.34

381.19

34

-9.867

0
-0.34

1.25 1-1,5

0.5

40

1841.47

73.66

73.32

307.53

1.75 1,5-2

0.5

139

536.8

74.62

147.94

232.92

2.25 2-2,5

0.5

175

371.47

65.01

212.95

167.91

2.75 2,5-3

0.5

179

294.13

52.65

265.93

114.92

6 3.25 3-3,5
7 3.75 3,5-4
VITAMIN B6 ARE

0.5
0.5

169
188

273.47
365.47

46.22
68.71

312.15
380.86

68.71
0.00

a
b
r

0.5 0-1

6.5738
-0.656
0.9953

Tmid

0.5
1.25
1.75
2.25
2.75
3.25
3.75

Ln (Du Du
kum)
5.9433
5.72857
9
5.45068
1
5.12342
5
4.74427
8
4.22987
1
-

Kel = -b
T 1/2
eliminasi

0.656
1.0564
02

KAFEIN RENAL
No.
Samp
el

interva
l
waktu
(jam)

0-1

t mid
(jam)

dt

Vu
(ml)

0.5

240

1-1,5

0.5

1.25

193

1,5-2

0.5

1.75

142

2-2,5

0.5

2.25

102

0.5
0.5
0.5

2.75
3.25
3.75

42
49
94

5
2,5-3
6
3-3,5
7
3,5-4
Y=-0.7422x +
2.5996
r=
0.9961
k eliminasi =
slope
K el = K= -B =
0,7422
2.59
A=
96

Cu
(ug/ml
)

Du/dt
(mg/ja
m)

Du

-1.699
13.60
4
13.28
1
12.25
4
11.45
6
10.98
9.193

-0.408

-0.408

0.5

5.251

2.626

1.25

1.66

3.772

1.886

1.75

1.33

2.500

1.250

2.25

0.92

0.962
1.076
1.728

0.481
0.538
0.864

2.75
3.25
3.75

-0.04
0.07
0.55

t mid
(jam)

Ln
Du/dt

0.74
22

-B=

t1/2 = 0,693/k
t1/2 =

0.93 jam

KAFEIN ARE
kode
sampe
l

Tmi
d

interv
al
waktu
(jam)

dt

Vu
(ml)

Cu
(g/m
l)

Du
(mg)

Du
kum

Du-Du
kum

Tmi
d

Ln (Du - Du
kum)

-0.41

-0.41

8.05

0.5

2.085977

2.63

2.22

5.43

1.89

4.10

3.54

1.25

5.35

2.29

0.48

6.24

1.40

0
1.699
13.60
4
13.28
1
12.25
4
11.45
6

0.5

0-1

240

1.25

1-1,5

0.5

193

1.75

1,5-2

0.5

142

2.25

2-2,5

0.5

102

2.75

2,5-3

0.5

42

3.25

3-3,5

0.5

49

10.98

0.54

6.78

0.86

3.75

3,5-4

0.5

94

9.193

0.86

7.64

0.00

1.2
5
1.7
5
2.2
5
2.7
5
3.2
5
3.7
5

1.691365
1.264404
0.829021
0.338015
-0.14602
-

a
b
r

2.8289
0.8991
0.9989

Kel = -b
T 1/2
eliminasi

0.8991
0.7707
71