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NervousSystemLabReport
Thislabreportwillincludeactionpotentialsalsoknownasimpulses,toxinseffectson
actionpotentials,andcranialnerveandreflexactionpotential.Actionpotentialsinamultipolar
neuron,wherethefirstpartoftheaxonistriggeredbyastimulusandrespondsintransmitting
millivoltsandthecellmembrane,riseandfallataconstantpace(allornothing).Depolarization
isthereductionofamembranesrestingpotentialsothatthemembranebecomesless
negative.Repolarizationisthestateintheactionpotentialprocessthatreturnsmembrane
potentialbacktoitsnegativevoltageafterthedepolarizationprocesshasoccurredby
selectivelyopeningandclosingofthepotassiumchannelsonthecellmembrane.Theperiod
whenaxonscantbestimulatedtogenerateanewactionpotentialiscalledtherefractoryperiod
whichlimitsimpulsestoanaverageof100persecond.Thefollowingfigureswilladdress
nervoussystemactionpotentialsstudies.
Figure1:Thegraphdemonstratesanormalactionpotentialaction
ActionPotentialToxins
Toxins
EffectsonActionPotentials
Maculotoxin
Blockssodiumchannels
Latrotoxin
Enhancesacetylcholinerelease
aBungarotoxin
Blocksacetylcholine[nicotinic]receptor
Tetrodotoxin
BlocksSodiumChannels
Apamin
Blockspotassiumchannels
Charybdotoxin
Blockspotassiumreceptors
Conotoxin
Onetypeblocksvoltagesensitivecalcium
channelsoneblocksvoltagesensitive
sodiumchannelsoneblocksAChreceptors
Figure2:
CranialNervesandtheirFunctions
Nerve
Function
Olfactory
Sensoryfibersconductimpulsesassociatedwiththesenseof
vision.
II
Optic
Sensoryfibersconductimpulsesassociatedwiththesenseof
vision.
III
Oculomotor
Motorfibersconductimpulsestomusclesthatraisetheeyelids,
movetheeyes,adjusttheamountoflightenteringtheeyes,and
focusthelenses.
IV
Trochlear
Motorfibersconductimpulsestomusclesthatmovetheeyes.
Trigeminal
Sensoryfibersconductimpulsesfromthesurfaceoftheeyes,
tearglands,scalp,forehead,anduppereyelids.
VI
Abducens
Motorfibersconductimpulsestomusclesthatmovetheeyes.
VII
Facial
Sensoryfibersconductimpulsesassociatedwithtastereceptors
oftheanteriortongue.
VIII Vestibulocochlear
Sensoryfibersconductimpulsesassociatedwiththesenseof
equilibrium.
IX
Glossopharyngeal
Sensoryfibersconductimpulsesfromthepharynx,tonsils,
posteriortongue,andcarotidarteries.
Vagus
Sensoryfibersconductimpulsesfromthepharynx,larynx,
esophagus,andvisceraofthethoraxandabdomen.
XI
Accessory
Motorfibersconductimpulsestomusclesofthesoftpalate,
pharynx,andlarynx.
XII
Hypoglossal
Motorfibersconductimpulsestomusclesthatmovethetongue
someproprioceptorinput.
Figure3:Whatthenervesareandhowtheyfunctions.
+ =Veryweakreaction
++=Weakreaction
+++=Strongreaction
Test
Results
Biceps
Triceps
+++
Brachioradialis
+++
Hoffmanns
Normal
Patellar
+++
Achilles
+++
Babinski
Normal
CrossedExtensor
Normal
Glabellar
Normal
Figure4:Inthefigureabove,variousreactiontestswereperformedandrecordedtoshowhow
theparticipantsreceptorneuronswerefunctioning.
Figure5:Demonstrationofthebicepsreflextest.