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BC-3300
Service Manual
Copyright
2008-2011 Shenzhen Mindray Bio-medical Electronics Co., Ltd.
For this Service Manual, the issued Date is 2011-02 (Version: 1.0).
used only for editorial purposes without the intention of improperly using them. They are the
property of their respective owners.
the electrical installation of the relevant room complies with the applicable national
Be sure to operate the analyzer under the situation specified in this manual;
otherwise, the analyzer will not work normally and the analysis results will
be unreliable, which would damage the analyzer components and cause
personal injury.
II
Warranty
THIS WARRANTY IS EXCLUSIVE AND IS IN LIEU OF ALL OTHER WARRANTIES,
EXPRESSED OR IMPLIED, INCLUDING WARRANTIES OF MERCHANTABILITY OR
FITNESS FOR ANY PARTICULAR PURPOSE.
Exemptions
Mindray's obligation or liability under this warranty does not include any transportation or other
charges or liability for direct, indirect or consequential damages or delay resulting from the
improper use or application of the product or the use of parts or accessories not approved by
Mindray or repairs by people other than Mindray authorized personnel.
This warranty shall not extend to:
any Mindray product which has been subjected to misuse, negligence or accident;
any Mindray product from which Mindray's original serial number tag or product
identification markings have been altered or removed;
Return Policy
Return Procedure
In the event that it becomes necessary to return this product or part of this product to Mindray,
the following procedure should be followed:
1.
Obtain return authorization: Contact the Mindray Service Department and obtain a
Customer Service Authorization (Mindray) number. The Mindray number must appear
on the outside of the shipping container. Returned shipments will not be accepted if
the Mindray number is not clearly visible. Please provide the model number, serial
III
Freight policy: The customer is responsible for freight charges when this product is
shipped to Mindray for service (this includes customs charges);
3.
Return address: Please send the part(s) or equipment to the address offered by
Customer Service department.
Company Contact
Manufacturer:
Address:
Phone:
Fax:
EC-Representative:
Address:
Phone:
0049-40-2513175
Fax:
0049-40-255726
IV
Table of Contents
Copyright I
Intellectual Property Statement I
Responsibility on the Manufacturer Party I
WarrantyIII
Exemptions III
Return PolicyIII
1
Scope 1-2
1.2.
Introduction 1-2
1.3.
1.4.
1.5.
Symbols 1-4
1.6.
Definitions 1-12
Analyzer Structure
2-1
2.1
2.2
2.3
2.4
2.5
Upgrade
3.1
1-1
3-1
Mechanical System
4-1
4.1
4.2
4.3
4.4
Fluidic System
51
5.1
5.2
5.3
5.4
5.5
Hardware System
6.1
6-1
Introduction 6-1
1
Table of Contents
6.2
6.3
6.4
6.5
6.6
6.7
6.8
6.9
Servicing
7-1
7.1
General 7-1
7.2
7.3
7.4
7.5
7.6
7.7
7.8
Replacing the valve, pumps, and other liquid system parts 7-20
7.9
7.10
7.11
7.12
7.13
7.14
7.15
7.16
7.17
7.18
7.19
7.20
7.21
8-1
10
Error Information
9-1
9.1
9.2
9.3
9.4
A-1
This chapter explains how to use this service manual. This manual states in detail the way to
service the BC-3600 and BC-3300 analyzers. Before servicing the BC-3600 and BC-3300,
read and understand the manual carefully for servicing the equipment properly and for your
safety.
This manual is to be used in conjunction with the operator's manuals of BC-3600 and
BC-3300.It does not contain information and procedures already covered in the operator's
manuals of BC-3600 and BC-3300.
Be sure to operate and service the analyzer strictly as instructed in this manual and the
operator's manuals.
1-1
1.1. Scope
To use this manual effectively, you need the following capabilities:
1.2. Introduction
This manual comprises 9 chapters and 6 appendices. Refer to the table below to find the
information you need.
If you want to
See
and BC-3300
learn about the installation requirements and the way to
BC-3300
learn about the fluidic system, reagent dosage, channels and
Chapter 7 Servicing
Chapter 8 Maintenance
Chapter 9 Troubleshooting
BC-3300
Parts
1-2
and BC-3300
Function Diagram
Appendix F Tubing
Meaning
all capital letters enclosed in [ ] indicate a key name (either on
[]
to
"Menu"
the "
All illustrations in this manual are provided as examples only. They may not necessarily reflect
your analyzer setup or data displayed.
It means
to press the desired item lightly with your finger; or to
Click
ENTER
DELETE
SELECT from
pull-down list
(for pull-down list)
1-3
1.5. Symbols
You will find the following symbols in this manual.
When you see
Then
read the statement below the symbol. The statement is
alerting you to an operating hazard that can cause
personnel injury.
read the statement below the symbol. The statement is
alerting you to a possibility of analyzer damage or unreliable
analysis results.
read the statement below the symbol. The statement is
alerting you to information that requires your attention.
read the statement below the symbol. The statement is
alerting you to a potentially biohazardous condition.
You may find the following symbols on the analyzer, reagents, controls or calibrators.
When you see
It means
CAUTION, CONSULT ACCOMPANYING
DOCUMENTS.
BIOLOGICAL RISK
HIGH VOLTAGE
ALTERNATING CURRENT
1-4
BATCH CODE
USE BY (YYYY-MM-DD)
SERIAL NUMBER
MEASUREMENT AUTHORIZATION
SYMBOL
DATE OF MANUFACTURE
MANUFACTURER
THIS ELECTRO-INFORMATIONAL
PRODUCT CONTAINS CERTAIN
POISONOUS OR HARMFUL SUBSTANCE.
ITS ENVIRONMENTAL LIFT TIME IS 20
YEARS. IT CAN BE USED WHTHIN 20
YEARS, AFTER THAT IT SHALL BE
RECYCLED.
Be sure to observe the following precautions for the safety of patients and operators when you
are servicing the analyzer.
When servicing the analyzer, be sure to turn off the power. Servicing the
analyzer when it is on may bring risk of electric shock or damage to
electronic components.
Connect the analyzer to a socket having sole fuse and protective switch. Do
1-5
To prevent personal injury during maintenance, keep your clothes, hairs and
hands from the moving parts, such as sample probe, clipper and piercer.
The reagents are irritating to eyes, skin and mucosa. Wear proper personal
protective equipment (e.g. gloves, lab coat, etc.) and follow safe laboratory
procedures when handling them in the laboratory.
If the reagents accidentally spill on your skin, wash them off with plenty of
water and if necessary, go see a doctor; if the reagents accidentally spill into
your eyes, wash them off with plenty of water and immediately go see a
doctor.
When the front cover is open, be sure to close the sample compartment door,
or the sample compartment assembly or the front cover may be damaged.
When transporting the analyzer, the screw at its bottom may scratch your
hands, please exercise caution or wear gloves.
1-6
All the analyzer components and surfaces are potentially infectious. Take
proper protective measures for operation or maintenance.
The sample probe tip is sharp and may contain biohazardous materials.
Exercise caution to avoid contact with the probe when working around it.
Figure 1-1
1-7
To avoid electric shock, disconnect power cord prior to removing or replacing fuse.
1-8
Figure 1-2
Warning, the sample probe is sharp and may contain biohazardous substance. Exercise
caution to avoid contact with the probe when working around it.
1-9
Figure 1-3
Warning, make sure the protective cover is properly installed before operation.
Warning
Do not put your hands close to the sampling assembly when the analyzer is running.
Warning, the sample probe is sharp and may contain biohazardous substance.
Exercise caution to avoid contact with the probe when working around it.
Warning, the sample probe is sharp and may contain biohazardous substance. Exercise
1-10
Figure 1-4
1-11
1.6. Definitions
There are two sampling mode: open vial mode and closed tube mode.
The operator presents the tube or open vial evacuated collection tube containing blood sample
to the sample probe, and press the "Aspirate" key to collect sample.
The analyzer of which the sampling mode is open vial is called open vial analyzer.
The operator puts the capped tube into the sample compartment, the analyzer collects sample
by piercing through the tube cap.
The analyzer of which the sampling mode is closed tube is called closed tube analyzer.
1-12
Analyzer Structure
Scope: the products can be applied for clinical diagnosing reference and scientific
research.
(100V-240V)10%
Input Power
180 VA
Frequency
50/601Hz
T3.15AH
2-1
Analyzer Structure
Height
Depth
Width
Figure 2-1Dimensional sketch map
Table2-2Dimension and weight
Width (mm)
Depth (mm)
Height (mm)
395
450
Weight (Kg)
28
2.2.4 Throughput
The throughput of open vial analyzers under whole blood mode is no less than 60 samples per
hour; the time needed for the analysis of one sample is no more than 60s (the sample dilution
time is not included for predilute mode).
The throughput of closed tube analyzers under whole blood mode is no less than 60 samples
per hour; the time needed for the analysis of one sample is no more than 60s (the sample
dilution time is not included for predilute mode).
2.2.5 Parameters
The analyzer determines 21 parameters (WBC, RBC, PLT, HGB, etc.) and 3 histograms
(WBC, RBC and PLT) of blood samples.
Table 2-3Table of parameters
English name
Abbreviation
WBC
Lymphocyte number
Lymph#
Mid#
Granulocyte number
Gran#
Lymphocyte percentage
Lymph%
2-2
Analyzer Structure
Mid-sized Cell percentage
Mid%
Granulocyte percentage
Gran%
RBC
Hemoglobin concentration
HGB
MCV
MCH
MCHC
RDW-CV
Variation
Red Blood Cell Distribution Width Standard
RDW-SD
Deviation
Hematocrit
HCT
Platelet count
PLT
MPV
PDW
Plateletcrit
PCT
P-LCR
P-LCC
Table2-4Table of histograms
White Blood Cell Histogram
WBC Histogram
RBC Histogram
PLT Histogram
Requirement
9
0.3 10 / L
RBC
0.03 10 / L
HGB
1g/L
HCT
0.5 %
PLT
5 10 / L
12
2-3
Analyzer Structure
2.2.6.2 Reproducibility
Run the sample meeting the reproducibility requirements for 10 consecutive times on the
analyzer, then calculate the CV(%) and SD, the requirements in Table 2-6 and 2-7 must be
met.
Parameter
CV%/SD
7.0 ~ 15.0 10 / L
2.5
WBC
4.0 ~ 6.9 10 / L
3.5
RBC
3.50 ~ 6.50 10
HGB
1.5
MCV
70.0~ 110.0 fL
0.5
12
2.0
/L
4.0
150 ~ 500 10 / L
9
PLT
100~149 10 / L
5.0
3050%
3.0
Lymph%
2050
1.5SD
Mid%
213
1.5SD
Gran%
3070
3.0SD
HCT
Condition
CV%
WBC
4.0 ~ 15.0 10 / L
9
12
RBC
3.50 ~ 6.50 10
4.0
2.0
/L
HGB
2.0
MCV
80.0 ~ 110.0 fL
1.5
PLT
8.0
100~500 10 / L
Linearity range
Deviation
range
blood mode)
WBC
0.0100.010 /L
9
100.130010 /L
(Whole
0.3010 /L 5
0.5010 /L or 5
18
2-4
Analyzer Structure
RBC
HGB
PLT
12
12
0.0510 /L or 5
0.0510 /L or 5
0280g/L
2g/L or 2
2g/L or 3
0100010 /L
9
1001300010 /L
HCT
12
08.0010 /L
060%
1010 /L or 10
1010 /L or 10
12
20
4% (HCT value) or 6%
(deviation)
Test suggestion:
12
When testing RBC linearity range 7.008.0010 /L, use sample of which the HCT 60%;
9
When testing PLT linearity range 1001300010 /L, use sample of which the RBC 6.
2.2.6.4 Carryover
The carryover impact of high concentration sample to low concentration sample.
Test method: mix the high value sample (centrifuged high value control or specialized high
value linearity control) within the range of
and then mix and test the low value sample (diluted low value control, dilution rate 1:10) within
the range of Table 2-9 for 3 consecutive times, then calculate the carryover. The requirements
in Table 2-10 must be met.
Table 2-9 Requirements on high and low value controls of carryover calculation
Parameter
Unit
High concentration
WBC
10 /L
Low concentration
> 15.0
< 3.0
RBC
12
10 /L
> 6.0
< 2.00
HGB
g/L
> 200
< 40
> 300
< 100
PLT
10 /L
Carryover
WBC
0.5
RBC
0.5
HGB
0.5
PLT
1.0
2.2.7 Functions
2.2.7.1 Startup and Shutdown
When starting up the analyzer, initialization will be performed to prepare the analyzer for
counting. Different startup cleaning sequence will be performed base on the latest shutdown
status to ensure the success of background counting. The analyzer provides the function to
skip fluidics initialization to the users of service level and above.
2-5
Analyzer Structure
The shutdown procedure will be performed according to different shutdown status.
2.2.7.5 Setup
Users can customize the settings of the analyzer on the software screen.
1.
2.
3.
For the FDA model, users can set whether to display or print RUO parameters
through the authorization protocol.
4.
For the FDA model, users can set "QC lockout", if this function is activated, sample
analysis can be started only after the daily QC passes.
2.2.7.6 Standby
The analyzer will enter standby mode when no fluidic operation has been performed for a
certain period of time. The analyzer will exit the standby mode when operation is triggered
by users.
Centrifugal tubes.
2-6
Analyzer Structure
Storage environment
environment
Running environment
Temperature
1530
-1040
1535
Humidity
30%85%
10%93%
30%85%
Atmospheric
70kPa106kPa
50kPa106kPa
70kPa106kPa
pressure
Fluid
Air flow
2-7
Reagents
Signal stream
Analyzer Structure
Figure 2-2 System function block diagram
2.3.2 Reagents
In order to ensure the accuracy of analysis results, you shall use the reagents, controls
and calibrators specified by Shenzhen Mindray Bio-medical Electronics Co., Ltd. For
details, refer to Table 2-12.
Table 2-12 Applicable reagents, controls calibrators
Item
Name
Diluent
M-30D DILUENT
Lyse
M-30CFL LYSE
Rinse
M-30R RINSE
Probe cleanser
PROBE CLEANSER
Control
B30 or BC-3D
Calibrator
2-8
Analyzer Structure
2-9
Analyzer Structure
2-10
Analyzer Structure
2.4.2 Password
The login service ID is "Service", password is "s 3600!", case sensitive and space required.
With service access level, you can perform all functions that are open to common users and
some other special functions:
1 Transfer factor calibration function:
1 Under whole blood mode, click "Menu">"Calibration">"Calibrator", finish the
calibration successfully, exit and save the calibration factors.
2 Click "Menu">"Calibration">"Transfer factor" to enter the screen in Figure 2-8,
run the sample used in the above step for 5 consecutive times under whole blood
mode, check if CV(%) meets the requirements in Table 2-13; if not, cancel a abnormal
result and calculate again (results of at least 5 analyses required), then check if the
requirements in Table 2-13 are met.
2-11
Analyzer Structure
WBC
RBC
HGB
MCV
PLT
2.0%
1.5%
1.5%
0.5%
4.0%
eter
CV
value
3 Click the "Predilute" button to switch to the screen of predilute mode, as Figure 2-9
shows;
2-12
Analyzer Structure
WBC
RBC
HGB
MCV
PLT
4.0%
2.0%
2.0%
1.5%
8.0%
eter
CV
value
2 The gain of WBC and RBC can be adjusted, see Figure 2-10;
2-13
Analyzer Structure
2-14
Analyzer Structure
as
Figure
2-13
shows,
click
"Menu""Setup""Service
Setup""Photocoupler Cal.", the dialog box shown in Figure 2-14 will pop up.
2-15
Analyzer Structure
2-16
Analyzer Structure
Click "Start" and then click "OK", the dialog box "Priming diluent" will pop up, then an
instruction message will be displayed, use the slot-headed screwdriver to rotate the
potentiometer VR1(RINSE) on the drive board (see Figure 2-15) counter-clockwise
until the D22 (RINSE-LED) turns on. Note: continue to rotate the VR1 for 180 degrees
after the D22 turns on.
Figure 2-15
Connect the connector of the rinse pickup tube to the fitting on the back panel of the
analyzer, click "OK" and then click "Finish", the dialog box "Priming rinse" will pop up,
check the calibration status then: if "Pass" is displayed (see Figure 2-16), that means
the calibration succeeded. The reference voltage and measured voltage are displayed
as "Reference(V)" (1.8-3.0V) and Actual(V) in Figure 2-16.
"PASS"
displayed
Figure 2-16
Note:
Rotate the VR1 for 180 degrees more after the D22 turns on, and make sure the LED
is illuminated.
Do not modify the value in the edit box Max(V), Min(V) and Factor(V);
If calibration cannot be done successfully due to the quality of the photocoupler itself
and the PCBA or photocoupler must be replaced, then recalibration is needed. The
dialog box "Remove the Rinse tube from the container and press [OK] to continue."
will pop up, press [OK] to drain the tubing; then do as instructed by the prompt - "1.
Adjust rinse photocoupler potentiometer till the RINSE-LED turns on; 2 Put the Rinse
tube into the container and press [OK]to close the dialog box; 3. Click [Finish] button"
to prime rinse after calibration is done.
2-17
Analyzer Structure
carryover
5 Check the replacement status of boards and CF card automatically. If the software
system is started and logged in by user of service level, then a prompt will guide the user
to restore the critical data.
Figure 2-18
1) If a new CF card is replaced, follow the guidance to select "Restore" and restore the
critical data to the CF card.
2) If a new data board is replaced, follow the guidance to select "Backup" and backup the
data to the data board.
3) If only the drive board is replaced, no special action shall be taken, the data will not be
2-18
Analyzer Structure
lost.
6 Users of the service level can export special information, see the figure below.
Figure 2-19
2-19
Analyzer Structure
2. Select network communication or serial port communication base on the physical
medium used.
3. If serial port communication is selected, communication can be realized when the
parameter settings of the serial port are identical with those of the LIS software. The
handshake function shall also be set up base on the LIS software used.
4. If network communication is selected, it is recommended that direct-coupled network
wire is used, and the major IP addresses such as 192.168.0. or 10.0.0.* are set up.
When connected to LAN, set up the IP address per the IP rules of the LAN. ACK
synchronous transmission shall also be set up base on the LIS software settings. If
you are not sure about that, use the default setup.
2-20
Upgrade
Figure 3-1
3Log in the BC-3600 with Service Engineer username and password.
4Run Setup Service Setup Setup Start Upgrade (see figure 3-2), and then click Yes
in the dialog box (see figure 3-3).
3-1
Upgrade
Figure 3-2
Figure 3-3
NOTES:
1Make sure the UBS storage connected well to the USB interface of the Analyzer.
2After you click Yes to start the upgrade, the system will start to read and analyze the
configuration in the UBS storage and this will last for about 1min. Please wait for the pop-up
upgrade confirmation dialog box.
3Do NOT remove the USB flash disk during the upgrade.
3-2
Upgrade
5software upgrade.
1) See the following software upgrade screen:
Figure 3-4
2) Click the Upgrade button to start the upgrade. You will see the upgrade preparation dialog.
(See figure 3-5)
Figure 3-5
3) The upgrade preparation lasts for about 1 min, after that, you will see the upgrade confirm
dialog. (See figure 3-6)
Figure 3-6
4) Click Yes to start the upgrade. (See figure 3-7)
3-3
Upgrade
Figure 3-7
5) You may need to restart the instrument for several times during the upgrade. (See figure
3-8)
Figure 3-8
6) Upgrade succeeded. (See figure 3-9)
Figure 3-9
7) Upgrade failed. (See figure 3-10)
3-4
Upgrade
Figure 3-10
8) After you finish all the process, please restart the instrument. (See figure 3-11)
Figure 3-11
6After upgrade finished, log in with the service engineer username and password. Run
Service Version to check upgrade items. (See figure 3-12)
Figure 3-12
3-5
Upgrade
Figure 3-13
2If upgrade failed, export the debug data. (See figure 3-14)
Figure 3-14
3-6
Mechanical System
1 --- Touchscreen
2 --- Indicator
5 --- Recorder
4-1
Mechanical System
1 --- Touchscreen
2 --- Indicator
6 --- Recorder
4-2
Mechanical System
4-3
Mechanical System
3 ---
4-4
Mechanical System
4-5
Mechanical System
3 ---
4-6
Mechanical System
3 ---
4-7
Fluidic System
5.1.3 Pump
Gas pump (GP): provide pressure to the vacuum chamber for generation of bubbles.
Waste pump (LP): draining probe wipe, WBC bath, RBC bath and vacuum chamber
and building vacuum.
5.1.4 Syringes
Diluent syringe (Dil-Syringe): full measuring range is 10ml; dispensing fixed quantity
of diluent to WBC and RBC bath, providing diluent to probe wipe.
Lyse syringe (Lyse-Syringe): full measuring range is 2.5ml, motivated by the same
motor with the diluent syringe; dispensing lyse.
5.1.5 Valves
Fluid valve and magnetic valve: diaphragm form, controlled by electric magnetic
power. Controlling the directional flow of fluid or air.
5.1.6 Baths
WBC bath: composed of front bath, back bath and aperture. Providing room for the
mixing of WBC sample; measuring HGB and WBC.
RBC bath: composed of front bath, back bath and aperture. Providing room for the
mixing of RBC sample; measuring RBC/PLT.
Vacuum chamber: build and store stable vacuum for the impedance counting of WBC
and RBC, clean the back baths and drain volumetric tubes.
Pressure chamber: build and store stable pressure for generation of bubbles in all
baths.
5-1
Fluidic System
WBC volumetric tube: its volume is 300ul, measuring volume of the WBC sample to
be analyzed.
RBC volumetric tube: its volume is 200ul, measuring volume of the RBC sample to
be analyzed.
5.1.8 Filters
Filter of WBC volumetric tube: filtrate the air entering the WBC volumetric tube.
Filter of RBC volumetric tube: filtrate the air entering the RBC volumetric tube.
Customized filter: filtrate the impurities and scraps from the probe wipe.
Filter of the isolation chamber: filtrate the impurities and scraps from the baths.
Name
sample
Whole blood
Predilute
Diluent
M-30D DILUENT
28mL
28mL
Lyse
M-30CFL LYSE
0.35mL
0.35mL
Rinse
M-30R RINSE
8mL
8mL
Probe
cleanser
PROBE CLEANSER
Control
B30BC-3D
Calibrator
S30SC-CAL PLUS
5-2
Fluidic System
5-3
Fluidic System
5-4
Fluidic System
All reagents:1)M-30PCFL lyse (lysing HGB, PLT and separating basophils from
other WBCs ); 2) M-30PD diluent (cleaning, providing reaction and measurement
environment)
Function description: Mix 9ul of blood and 2.35ml of diluent in the WBC bath,
provide 34ul of first dilution sample to the RBC bath and add 0.35ml of lyse into it,
mix them; then aspirate the mixed sample into the back bath through the aperture by
the vacuum of the vacuum chamber. The cells are analyzed when they pass the
aperture. Volume of the sample analyzed is measured by the volumetric tube.
5-5
Fluidic System
Function description: the sample probe aspirates 34ul of sample (dilution ratio:
1:262.11) from the WBC bath, add 0.8ml of mixture of the sample and diluent into the
RBC bath to form the sample of dilution ratio 1:20000 with another 1.8ml of diluent;
Mix them and aspirate the sample by vacuum of the vacuum chamber into the back
bath through the aperture. The cells are analyzed when they pass the aperture.
Volume of the sample analyzed is measured by the volumetric tube.
Fluidic System
Initialize position of the sample probe by command INIT.
?
?
RBC
WBC
Diluent
a)
Blood
sample
b)
?
?
RBC
RBC
WBC
c)
First
dilutio
n
sampl
e
Secon
d
dilution
sample
?
WBC
d)
Sampling (0~12.6s)
Pre-piercing: the pre-piercing process of sample probe (for closed tube models)
to release the pressure in the tube before sample aspiration.
Cleaning the exterior and interior walls of sample probe: when piercing finishes, the sample
probe ascends to home position, meanwhile its exterior and interior walls are washed. See the
following figure.
5-7
Fluidic System
V01
V01
Diluent
V02
V02
V04
Diluent
V04
10ml
10ml
100ul
100ul
V19
V19
Waste
Waste
a) Wash exterior wall of
sample probe
The sample probe descends to the sampling position, and then moves to the
piercing position, the syringe withdraws for 2ul to create separating bubbles.
Then the sample probe descends to the lowest aspirating position to prepare for
sample aspirating. Besides, the fluidic passages of draining and dispensing of
the WBC bath are indicated in Figure 5- 5 and Figure 5- 6; Under the effect of
vacuum, rinse flows through and washes the WBC and RBC back baths and
their volumetric tubes, the fluidic passage of washing the WBC back bath and
volumetric tube is indicated in Figure 5- 7; When the washing progress ends,
Valve 5 and 6 opens to drain the volumetric tubes.
5-8
Fluidic System
V01
Diluent
V04
V02
V03
10mL
SR3
2.5mL
(SR1)
WBC
bath
Lyse
Isolation
chamber
V16
Waste
Figure 5- 5 Fluidic passage of draining of the WBC bath
V01
Diluent
V04
V02
V03
2.5mL
(SR1)
WBC
bath
10mL
SR3
lyse
5-9
Fluidic System
V05
V07
Atmosp
heric
pressure
WBC
bath
Volumetric
board
Pressure
V14
Rinse
Vacuum
chamber
V09
Isolation
chamber
V10
V18
V16
Waste
Figure 5- 7Fluidic passages of washing WBC back bath and volumetric tube
After sample dispensing of the WBC bath finishes (7s) and the fluid level
stabilizes, the HGB voltage and WBC aperture voltage (the constant-current
source is opened at 10.5s in advance) is read at 10.5s.
Dispensing sample for the second time: the sample probe moves to the top of
WBC bath and descends into the bath; the diluent syringe dispenses 1150 ul of
diluent into the WBC bath, then the sample probe dispensed 9 ul of sample and
swings; when sample dispensing finishes, the diluent syringe dispenses 1200ul
of diluent into the WBC bath again; Valve 10 opens, and blows one small bubble
and 3 big bubbles into the WBC bath in turn. By now, the first dilution of sample
finishes.
The sample probe ascends with its exterior and interior walls washed: when the
second sample dispensing finishes, the sample probe ascends to home position
with its exterior and interior walls washed; besides, 2700ul of diluent is
dispensed into the RBC bath.
5-10
Fluidic System
Second aspiration in the WBC bath: the sample probe descends to the WBC
bath and aspirates 34 ul of fluid at 19.9~21s.Valve 17 opens, and the RBC bath
is drained.
The sample probe ascends: when the second aspiration finishes, the sample
probe ascends to home position with its exterior wall washed; besides, 1800 ul
of diluent is added to the RBC bath at 24.5~25.5s.
Adding sample to RBC bath, and lyse to WBC bath: the sample probe moves to
the RBC bath and descends into the bath; the lyse syringe dispenses 350ul of
lyse into the WBC bath, the fluidic passage is indicated in Figure 5- 8; the diluent
syringe discharges 800 ul of fluid (mixture of first dilution sample and diluent)
through the sample probe. Valve 10 opens at 26.65~27.25s, the pressure
chamber blows bubbles into the WBC bath; then a bubble that can last for 0.05s
is blowed into the WBC bath, and 3 bubbles are blowed into the RBC bath in
turn; Finally, the sample probe restores to the original position with its exterior
wall washed.
V03
2.5mL
(SR1)
WBC
bath
Lyse
Other actions finished during the sample dispensing, dilution and mixing
procedure:
Build the vacuum needed for analysis, total time consumed is 7.9s;
The sample compartment door opens at 12s to prepare for the next analysis
cycle.
Analysis
Fluidic System
V07
V05
V06
V08
Volumetric
board
RBC
bath
WBC
bath
Volumetric
board
V14
Vacuum
chamber
V15
Rinse
V18
Waste
Fluid discharging of RBC and WBC baths: open valve 17, the RBC bath starts to
discharge fluid; open valve 16, the WBC bath starts to discharge fluid;
Fluid dispensing of RBC and WBC baths: 1400 ul of fluid is dispensed into the
RBC and WBC bath respectively;
Washing RBC and WBC back baths: when valve 8 and valve 15 open at the
same time, the RBC back bath will be washed by rinse under the effect of
vacuum; when valve 7 and valve 14 open at the same time, the WBC back bath
will be washed by rinse under the effect of vacuum.
Draining the vacuum chamber: open valve 9 to drain the vacuum chamber.
Resetting of the diluent syringe and sample probe assembly: the diluent syringe
aspirates 2100 ul of fluid, then valve 1 opens, the syringe returns to home
position and dispenses fluid to the RBC bath at the same time; the sample probe
assembly returns to home position.
The sample probe aspirates air bar and returns to home position: the sample
probe moves to the piercing position and withdraws for 2ul and then returns to
home position.
Zapping: zapping starts when fluid dispensing of WBC bath completes for a
while.
Calculating the volume of rinse consumed: the software reads from the
command to calculate the volume of rinse consumed.
Detecting rinse status: sensor in the analyzer detects if the rinse container is
empty; when alarming for no rinse, the residual volume of rinse must be able to
support the on-going analysis.
The major difference between the whole blood analysis sequences of open vial models and
closed tube models lies in the sampling procedure, the open vial sequence involves no
piercing action, but its sampling time point and the cleaning action after sampling are the same
5-12
Fluidic System
with those of the closed tube sequence, therefore the whole blood analysis sequences of open
vial models will not introduced in detail.
Fluidic System
1. This sequence applies to open vial models only.
2. The sequence cleans the exterior wall of the sample probe, initializes diluent syringe
by command INIT; the sampling syringe withdraws for 2ul to create a separating air
bar, the system restores to "Ready" status.
Sampling:
1. The diluent syringe withdraws for 100ul through the probe wipe tube;
2. WBC/RBC bath is zapped for 3s;
3. The diluent syringe aspirates 146.34ul of sample;
4. When aspirating finishes, valve 01 closes 0.1s after valve 04 closes.
1. The diluent syringe pushes sample in the sampling tube into the WBC bath to form
the first dilution sample;
2. Sample volume of the second aspiration is 37.39ul;
3. The predilute measurement takes 1.5s more than the whole blood measurement due
to the zapping action added before analysis;
4. The other parts of sequence are the same as those of the whole blood measurement
sequence, only the fluid volumes are different in some steps.
5. The major difference between the closed tube and open vial models is the position of
the sample probe under the "Ready" status.
This sequence includes the troubleshooting sequence 1, fluidics initializing sequence and
startup sequence after normal shutdown.
1. Troubleshooting sequence 1, refer to the corresponding section.
2. Fluidics initializing sequence, refer to the corresponding section.
3. Startup after normal shutdown
5-14
Fluidic System
There are zapping and flushing operations at the beginning to avoid clogging after
long term of probe cleanser soak.
0.5ml of lyse is discharged to make sure the tube mouth is filled with reagent.
Push back 200ul of diluent to the cleanser tube to wash off the cleanser at the
closed end of valve 12.
Empty RBC charging line to avoid crystallizing of the cleanser spills on the wall of
the bath which may influence the PLT background.
Empty the sample probe and dispense fluid: after emptying the sampling tube,
5-15
Fluidic System
dispense fluid at a higher speed so that the bubbles in the sampling tube can be
removed effectively.
6
The sample probe dispenses fluid in the WBC bath: removing all the bubbles in
the sampling tube.
Cleaning the two baths: cleanser volumes of WBC bath 4ml, 4.6ml, 5.5ml;
cleanser volumes of RBC bath 4ml, 4ml, 5ml, generating bubbles during the
cleaning process to strengthen the cleaning effect.
Emptying WBC, RBC baths and the back baths, switching among valve 16 ,17, 7
and 8 to strengthen the cleaning effect.
This sequence includes the troubleshooting sequence 1, fluidics initializing sequence and
startup sequence after normal shutdown.
1. Troubleshooting sequence 1, refer to the corresponding section.
2. Fluidics initializing sequence, refer to the corresponding section.
3. Startup after normal shutdown
When starting up the analyzer after abnormal shutdown, there may be some
5-16
Fluidic System
residual sample in the fluidic components, so the exterior and interior walls of
the sample probe must be cleaned repeatedly by fluid discharging of the
sample probe and probe wipe.
2
3
0.5ml of lyse is discharged to make sure the tube mouth is filled with reagent.
Push back 200ul of diluent to the cleanser tube to wash off the cleanser at the
closed end of valve 12.
Remove the bubbles in the sampling tube through fluid discharging for multiple
times.
Clean the two baths repeatedly to remove the possible residual sample.
Wash tubes of the back baths twice to remove the residual sample in the tubes
or volumetric tubes.
This sequence includes the troubleshooting sequence 1, fluidics initializing sequence and
overall reagent priming sequence.
1. Troubleshooting sequence 1, refer to the corresponding section.
2. Fluidics initializing sequence, refer to the corresponding section.
3. See section 5.5.3.5 for the overall reagent priming sequence.
Fluidic System
6. Wash the tubes of the back baths. Empty the vacuum chamber and release vacuum.
Soaking procedure:
5-18
Fluidic System
Introduction: the soaking process consists of three steps. Step 1: soak the WBC aperture
and interior wall of the sample probe with 100% probe cleanser. Step 2: soak the WBC and
RBC front/back baths with 30.77% and 38.46% probe cleanser respectively. Step 3: soak the
WBC and RBC front/back baths with 26.32% and 21.05% probe cleanser respectively. The
operations are:
1. The sampling syringe withdraws for 2ul to form a separating air bar.
2. The sample probe aspirates 1.8ml of probe cleanser, the two baths are drained,
the sample probe ascends with its exterior wall washed.
3. The sample probe dispenses 1ml of probe cleanser into the WBC bath to form
100% probe cleanser.
4. The sample probe dispenses 2.6ml of mixture of probe cleanser and diluent into
the RBC bath to form the high concentration compound (30.77%) for the first
soak.
5. The sample probe dispenses 1.6ml of diluent into the WBC bath to form the high
concentration compound (38.46%) for the first soak.
5-19
Fluidic System
6. After soaking for about 2 minutes, dispenses 1.2ml of diluent to the two baths to
dilute the probe cleanser, which will be used for the long term soaking of the front
and back baths (WBC:26.32%; RBC:21.05%).
7. Build vacuum and aspirate fluid: aspirate for 6s from the WBC bath, the volume
aspirated is about 232ul; aspirate for 8s from the RBC bath, the volume aspirated
is about 236ul; When the aspiration finishes, release the vacuum in the vacuum
chamber.
8. Meanwhile, the sample probe aspirates 50ul of fluid from the RBC bath for
soaking of the interior wall of sample probe and the tube.
9. Soak the tubes for 2 minutes and then start the cleaning procedure.
Cleaning procedure:
5-20
Fluidic System
Introduction: the front and back baths, sampling tube, waste valve shall be cleaned to remove
residual probe cleanser.
1. Add probe cleanser to the WBC bath; when draining the WBC bath, switch on/off
valve 16 for multiple times to soak the waste valve with probe cleanser (for about
5s) to remove residual probe cleanser.
2. Add probe cleanser to the RBC bath; when draining the RBC bath, switch on/off
valve 17 for multiple times to soak the waste valve with probe cleanser (for about
5s) to remove residual probe cleanser.
5-21
Fluidic System
3. The sample probe dispenses 7.8ml of probe cleanser to the RBC bath to clean
the sampling tube and remove bubbles in the tubing.
4. Discharge fluid to the probe wipe twice, meanwhile the sample probe ascends to
avoid residual probe cleanser on the exterior wall of the sample probe or in the
probe wipe.
5. Build vacuum, wash tube of the back bath, switch on/off valve 7 and 8 for
multiple times.
6. Empty the vacuum chamber, switch on/off valve 18 for multiple times.
7. Drain the baths and build pressure to 40kpa.
8. Flushing the apertures.
9. Drain the two baths and add 3.5ml of fluid into the baths respectively, zap the
baths for 4s and build vacuum to -24kp.
10. Wash the back baths, switch on/off valve 7 and 8 for multiple times to strengthen
the cleaning effect of the valves and remove residual probe cleanser.
11. Empty the vacuum, switch on/off valve 18 for multiple times to strengthen the
cleaning effect of the valves and remove residual probe cleanser.
12. Release the pressure, the analyzer restores to "Ready" status.
5-22
Fluidic System
Introduction: the intensified probe cleanser soak procedure is almost the same as the general
probe cleanser soak procedure, the only difference lies in the dilution ratio of probe cleanser.
5-23
Fluidic System
Cleaning procedure:
The cleaning operations of the intensified and general probe cleanser soak procedure
are almost the same, the only difference lies in the occurrence time of the operation.
Introduction:
1.
Build vacuum in the vacuum chamber to drain the back bath and rinse
tubes.
2.
Drain the RBC bath, the diluent syringe withdraws for 1.3ml to drain the
charging line of RBC bath.
3.
The lyse syringe aspirates and discharges lyse to the WBC bath for
multiple times to drain the lyse tube.
5-24
Fluidic System
4.
The diluent syringe aspirates and discharges diluent to the WBC bath for
multiple times to drain the diluent tube.
5.
6.
The sample probe goes inside the WBC bath to drain the sampling tube.
7.
Drain the charging line and the waste tube of the probe wipe.
8.
9.
After build vacuum in the vacuum chamber, open the rinse tubes and empty
tubes of the back baths.
10. Empty the vacuum chamber and build vacuum at the same time, open V5
and V6 of the volumetric tube and dry the volumetric tube.
11. Release vacuum and pressure, the syringes return to home position, the
sample probe returns to the sampling position.
5-25
Hardware System
6.1 Introduction
The hardware system consists of 8 boards, which are power board, data board, drive board,
indicator board, touch screen control board, volumetric boars, sample compartment connector
board, and USB interface board; the system also includes the drive and detect components
that require power supply (such as motors, valves, pumps, sensors, display, and filter of input
power) and the wires connecting boards and components.
2.
3.
Central control system: data collection and processing, result display, sample
storage, etc. Besides, the central control system controls and responds to all
peripherals.
4.
Hardware System
sending alarms.
5.
6-2
Hardware System
6-3
Hardware System
6-4
Hardware System
(2) After completing step (1), plug the two wires on of the drive board in turn to see if the power
can be started; if yes, the problem of the drive board can be excluded, the data board needs to be
replace; if no, unplug the wire of the volumetric board; if the power can be started, that means the
volumetric board or its wire is short-circuited, the volumetric board or its wire shall be replaced; if
not, that means the drive board is short-circuited, the drive board shall be replaced.
If the power can be started normally, troubleshoot the error per the following sections.
6.2.2 Structure
Introduction of Functions
See Figure 6-5 for the structural diagram of the data board.
Hardware System
Data collection
2. Digital module
Preprocessing of data
Hardware System
Description
Converting the input power into the power that meets the requirement of the board.
Driving, collecting, adjusting, amplifying the RBC, PLT, WBC and HGB signals, and sending
the signal to A/D part for conversion.
Data collection
The A/D circuit converts the analog signals in to digital signals that can be recognized by the
digital module (FPGA and CPU), and sends the signals to FPGA for processing.
Preprocessing of data
The FPGA filters the digital signals collected by the A/D part, saves the particle parameters
and sends the data to CPU through Flexbus by means like interrupt, etc.
The CPU module provides the platform for software operation to the system, and provides
interfaces for peripherals, including interfaces of the drive board, LIS system, recorder, indicator
board, touchscreen control board, LCD display, Ethernet, USB printer, USB barcode scanner,
keyboard and USB, etc. It also provides JTAG interface for the online programming of FPGA
configuration chip and BDM interface for CPU debugging.
The FPGA provides control logic and interfaces for LCD, recorder, CF card, touchscreen and
door detector.
Definition of Interfaces
There are 19 interface sockets on the data board, the functions of the interfaces are listed in
Table 6-1. See Figure 6-8 for the position of the interfaces.
Table 6-1 Functions of data board interfaces
Interface
Function
No. of pins
Description
P1
Interface of CF card
50
J1
Connect RBC/PLT
sensor
J2
J3
J4
circuit
power
6-7
Hardware System
J5
zapping
Connect zapping
power
J7
Interface of recorder
J8
10
J9
20
J12
11
J13
26
J14
J16
24
20
J18
analog circuit
J20
12
J22
Ethernet interface
10
J29
J30
6-8
Hardware System
J17
J14
J7
J16
J9
J8
J3
J4
J30
J29
J5
J20
J22
J2
J12
J1
J13
J18
P1
Function
+5V_POWER
+12V_POWER
FPGA_LED
Indicator of FPGA logical work, it filters when the logical work goes on
normally
D3/D7/D8/D9
D17
6-9
Hardware System
D20
D21
D22
D38
D44
D45
D46
D47
D48
D70
D71/D72
D73
D100/D101
D102
D103
Name or location
of test points
Description
VCC
Digital 5V power
VDD
D_1V8
D_1V5
D_2V5
D_1V25VRF
D_1V25VTT
Hardware System
8
D_1V2_FPGA
TP36
10
TP37
11
TP38
12
TP39
13
TP168
14
IRQ1
15
IRQ2
16
IRQ3
17
IRQ4
18
IRQ5
19
IRQ6
20
IRQ7
14
+12V
15
-12V
16
+5V
Analog 5V power
17
-5V
18
+56V
19
NCONST
20
NSEL_R
21
NSEL_W
22
NBURN
23
NHLED
24
RBC1
25
RBC2
26
RBC5
27
RBC
28
RBCF
29
PLT1
30
PLT2
31
PLT
32
PLTF
33
WBC1
34
WBC2
35
WBC3
6-11
Hardware System
36
WBC
37
WBCF
38
HGB1
39
HGB
40
VR_H
41
VR_W
42
VR_R
43
VR_P
44
HGND
Digital ground
45
-12VM
46
+12VM
47
+56VM
48
RHOLE
49
WHOLE
Note: refer to Table 6-3 for the location of all test points.
Definition of Keys
See Table 6-4 for the definition of keys on the data board:
Table 6-4 Definition of keys on the data board
No.
Function
S12
6.2.4 Troubleshooting
Table 6-5 lists the common errors and troubleshooting methods of the data board from the
hardware point of view, the errors caused by software are not included. But many hardware errors
must be inspected by the software.
You need to check the following items before troubleshooting the errors:
1. Check if the wires are firmly connected to the data board;
2. Check if the wires are connected to the sockets of the same No., and if the wires are
cracked or damaged.
3. Check if the input power of socket L18 is normal (test +5V and +12V with a multimeter).
4. Check if the indicator of the data board is in normal condition according to Table 6-5.
After confirming all the above items are in normal condition, do as instructed in Table 6-5 to
troubleshoot the errors.
Table 6-5 Analyzing and handling data board errors
No.
1
Phenomenon
LCD
blanks
Judging criteria
1: Press the reset button S12 on the data board, if the
6-12
Solution
Press S12
Hardware System
out
the
connection
wires
of
the
inverter
and
LCD
display.
Replace
3: Replace the connection wires of the data board and
the inverter and LCD display, if the error is cleared, it
can be concluded as a connection wire failure; if not, do
step 4.
the
connection
wires
of
the
inverter
and
LCD
display.
4Test the resistance of F4 with multimter, if the result is
not 0, the error is caused by the protective tube F4; if
not, do step 5.
5: Test voltage of the test point VDD with the multimeter,
if the result is not 3.135V~3.465V, U62 failure can be
concluded; if not, do step 6.
6: Test voltage of the test point D_2V5 with the
multimeter, if the result is not 2.375V~2.625V, U60
failure can be concluded; if not, do step 7.
7: Test voltage of the test point D_1V8 with the
multimeter, if the result is not 1.71V~1.89V, U63 failure
can be concluded; if not, do step 8.
8: Test voltage of the test point D_1V5 with the
multimeter, if the result is not 1.425V~1.575V, U61
failure can be concluded; if not, do step 9.
9: Test voltages of the test points D_1V25VRF and
D_1V25VTT with the multimeter, if the results are not
1.188V~1.313V, U65 failure can be concluded; if not, do
step 10.
6-13
Replace
data board
the
Hardware System
Replace
display
assembly
the
Replug
1: Replug the connection wires of the data board and
the inverter and LCD display, if the error is cleared, it
can be concluded as an insecure connection failure; if
not, do step 2.
the
connection
wires
of
the
inverter
and
LCD
display.
Replace
2: Replace the connection wires of the data board and
2
LCD display
flickers
the
connection
wires
of
the
inverter
and
LCD
display.
3: Replace the data board, if the error is cleared, the
display memory (U4) failure or crystal oscillator (X6)
failure can be concluded; if not, do step 4.
Replace
data board
Replace
display
assembly
6-14
the
the
Hardware System
Replug
the
connection
wire of the data
board and LCD
display
Replace
connection
Spotted LCD
display
the
Cut
off
solder
the
joint
with a knife.
Replace
data board
Replace
display
assembly
the
the
Set IP of the
PC to 10.0.0.3
not, do step 2.
Fail to
3
connect
network
The USB
5
interfaces
cannot be
used
6-15
Replace
the
data board
Replug
or
replace
the
network wire
Upgrade
the
kernel to the
correct
version.
Hardware System
Replace
the
data board
Replace
the
data board
Replug
are all on, replug the wire connected to the USB port. If
wire connected
to
port
the
the
USB
Replace
devices
connected
to
Replace
the
connection
wire of printer
with a qualified
one
Replace
the
data board
resets each
time after
startup
Replace
button battery
the
concluded.
12V
analog
voltage
7
abnormal
6-16
Replace
data board
the
Hardware System
data board failure can be concluded.
1 Condition: the power wire is firmly connected.
2 If D17 is off, that indicates the data board failure; if
-12V analog
8
not, do step 3.
voltage
abnormal
Replace
the
data board
56V voltage
abnormal
Replace
2 Test voltage of the test point +56V or +56VM with the
the
data board
voltage
abnormal
Replace
the
data board
Analog -5V
11
voltage
abnormal
Replace
the
data board
HGB blank
10
voltage
Replace
HGB lamp
abnormal
2. See if the HGB lamp is off, if so, then the HGB lamp
failure can be concluded; if not, proceed with the
6-17
the
Hardware System
next step.
1 Test voltage of the HGB test point with the
multimeter, if the result is outside [3.2V4.9V], that
indicates the ADC failure, the data board shall be
replaced; if the result is outside [3.2V 4.9V],
Replace
the
data board
Replace
the
HGB lamp
Replace
the
data board
6.3.2 Structure
The drive board consists of the power supply, central control module, detection module and power
drive module.
6-18
Hardware System
6-19
Hardware System
Figure 6-10 View of the drive board sockets and indicators
6-20
Hardware System
6.3.6 Troubleshooting
1) Checks before troubleshooting
Before troubleshooting the drive board, you should first check if the wires are firmly connected, if
they are connected to the sockets of the same No., and if the wires are damaged.
When you suspect that drive board failure occurs, check if the indicators are under normal status
per the following table.
Table 6-6 Status of drive board indicators
Indicator
No.
Normal
Abnormal
Description
If the indicator is off, that means the 5V
power supply is abnormal. Cut off the power
of the analyzer, test the resistance of the 5V
5V
indicator
On
Off
3.3V
indicator
On
Off
12V
indicator
On
Off
24V
indicator
D9
On
Off
6-21
Hardware System
the breakdown of all motors. Cut off the
power of the analyzer, test the resistance of
the 24V fuse (see Figure 6-11) with the
multimeter, if the result is over 1 ohm, that
indicates the 24V fuse is damaged and the
drive board needs to be replaced; if not,
check if the 24V output voltage of the power
board is within the range [22V30V].
If the indicator does not flicker, that means
the MCU is not working normally. First check
if the 3.3V power is under normal status
(voltage range [3.15V,3.45V]) by observing
MCU
indicator
D49
Flickers
Does not
every 1s
flicker
FPGA
indicator
D51
Flickers
Does not
every 1s
flicker
If all the indicators are confirmed to be ok, check if the MCU and FPGA versions are correct
on the software screen (Click the menu option"Service" "Version Info."); if yes, troubleshoot
the error as instructed in the following section.
2) Troubleshooting
You can roughly locate the error by the alarm, then accurately locate the error by its type and
dispose it, see Table 6-7.
Table 6-7 Troubleshooting methods
No.
Type
Description
Troubleshooting Methods
6-22
Hardware System
errors include
Check
if
the
luminous
surface
of
the
breakdown;
working, but
motor or
photocoupler
Motors and
a Motor
b Motor is
error is reported;
photocouplers
Abnormal
sounding of
motors
Breakdown of
2
Valves
valves is
suspected
Hardware System
yes, replug or replace the wire.
3 If step 2 cannot clear the error, connect the wire
of another valve to the valve, then check if the error
lies in the valve drive circuit or the valve itself at the
self-test screen (if failure of valve 2 is suspected,
connect the wire of valve 3 to valve 2, then open
and close valve 3 at the self-test screen, if it can be
open and closed normally, that means the drive
board has been damaged and shall be replaced;
otherwise valve 2 is damaged and shall be
replaced).
1 Check if the pumps can work normally at the
self-test screen, if yes, the error shall be
a Abnormal
Pumps
pressure is
reported
b Breakdown of
pumps
Communication
Communication
error is reported
wire.
3 If the error cannot be cleared, replace the wire.
4 If the error persists, replace the drive board and
data board in turn.
1 Perform rinse photocoupler calibration to see if
the error can be cleared. If the calibration cannot
be perform successfully, replace the drive board
Rinse
photocoupler
Rinse
photocoupler
error is reported
Hardware System
photocoupler assembly.
4 If the error persists, it may be caused by aging of
the rinse tube.
1 Check if the waste wire is loose or damaged, if
6
Waste sensor
Incorrect alarm
yes, pull off and clean the wire and then replug it,
of waste status
a The aspirate
respond when
being pressed.
7
Micro-switch
b The sample
compartment
door cannot be
closed.
reinstall them.
6.4.2 Structure
Function
The functional diagram of the power system is as follows:
6-25
Hardware System
Description:
The power board works under the 100-240V(10%) AC input voltage 50/60Hz(2Hz).Once the AC
power switch is on, all the circuits start to work, the D5V, A+12V, A-12V, AC130V, P12V, and P24V
all output.
The load of each circuit is listed in the following table:
Table 6-8 Properties of output voltage
Voltage
Load
regulatio
regulatio
n factor
n factor
5A
1%
0.3A
0.3A
0.01A
0.2A
0.2A
2A
Minimum
Normal
Peak
Load
Load
Load
D5V
1.5A
3A
A+12V
0.05A
A-12V
P12V
Voltage
Range of
Ripple&
output voltage
Noise
3%
4.85~5.25V
100mV
1%
3%
11. 5~12. 5V
100mV
0.2A
1%
3%
-11.5~-12.5V
100mV
4A
1%
3%
11.5~12.5V
150mV
6-26
Hardware System
P24V
0A
0.3A
1.5A
1%
10%
22~30V
150mV
AC120V
0mA
0mA
60mA
110~140V(RMS)
11W
53W
123W
Output
Power
Peak load means the Peak Load current of P12V and P24V in the cycle of 60S is no more
than 1S.
D5V has a single ground, A12V share one ground, P12V and P24V share one ground;
AC120V shall be alternate current(square wave), frequency is 50Hz+/-10Hz.
Definition of Interfaces
The power board has 6 outgoing interfaces, 4 of them (J1, J2, J3 and J4) are connected by
sockets; The AC input wires L and N are connected to external sockets, PCB No.s are L and N;
the inverse board is connected to the power board by a socket, PCB No. is PCBA1.See the
following figure for the position of each interface on the board.
Definition
6-27
Hardware System
Connected to the positive end of the P24V
1/2
output voltage
Connected to the positive end of the P12V
3/4
output voltage
5/6/7/8
9/10
11/12
NC
13/14
Socket
Socket Model
No.
D5V
J1
P12V, P24V
J2
A+12V, A-12V
J3
AC120V
J4
Location
Function
Reference Value
C123.+
39020V
U12.9
7.5V
C107.+
VCC voltage
17V~22.5V
C19
VDD voltage
121V
U1.8
Reference voltage of U1
5V
C111.+
50.5V
D5V
7
C117.+
A+12V output
120.5V
C115.-
A-12V output
-120.5V
6-28
Hardware System
C121.
121V
10
U3.14
U3 reference voltage
5V
11
C119.+
22~27V
12
C120.+
120.5V
When disassembling and installing the boards, cut off the power and pull out
the power wire.
Installing:
Do the above steps in reverse order
Verification: 1 Check if the ground wire of AC input socket on the casing is securely connected to
the conductive part of the analyzer chassis.
7 Connect the power wire and switch on the AC switch, the analyzer enters initializing status
and the indicators on the board turn on.
Make sure the power supply assembly and the analyzer chassis are fastened
by screws.
The disassembling operation must be done after the power board and the
surrounded parts cool down.
6.4.5 Troubleshooting
The errors of the power board can be troubleshooted per the following procedure.
6-29
Hardware System
6-30
Hardware System
6.5.2 Troubleshooting
When the USB interface on the front cover cannot be used, do as follows:
1Check if the data board is working properly, if not, handle the problem of the data board first.
2Check if the wire connecting the USB interface board and the data board is loose or damaged,
if yes, replug or replace the wire; if not, check if the USB interface board is cover by fluid spills,
replace the board if so.
3If the problems mentioned in the above step are excluded, replace the data board.
6-31
Hardware System
Figure 6-16 Touchscreen Control Board
6.6.2 Troubleshooting
No.
Phenomenon
Possible Cause
Solution
1
Check if the data board is working
properly, if not, handle the problem of the
data board first.
of
touchscreen control
board/Failure
Failure
The
1
touchscreen
of
touchscreen/the
connection wire is
loose
3
If the above problems are excluded,
replace the touchscreen control board.
4
If the error cannot be cleared, replace
the touchscreen.
1
Check if there is any crack on the
touchscreen,
the
touchscreen
touchscreen,
cursor
can
touchscreen.
move
the touchscreen is
When
the
the
2
pressing
only
horizontally or
loose/the
touchscreen
vertically
move to a certain
area
if
yes,
replace
the
2
Replug the wire
is
cracked
The touchscreen is
1
Perform touchscreen calibration.
not
calibrated/the
touchscreen
is
cracked
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Hardware System
6.7.2 Troubleshooting
No.
Type
Description
Troubleshooting Methods
1
Click "Service"
"System Test", and then click
the "WBC Test Time" and "RBC Test Time" buttons
Including
Abnormal
1
detection
of fluid
but
2
If the error cannot be cleared, check if the data
following errors:
1
WBC clog
2
WBC bubbles
3
RBC clog
4
RBC bubbles
Hardware System
first.
4
Check if the fluid in the WBC or RBC tube is not
flowing or is flowing slowly; if yes, clear the error
first.
5
The analysis starting indicator shall turn on when
fluid reaches the analysis starting photocoupler, and
when fluid reaches the analysis ending photocoupler,
the analysis ending indicator shall turn on, then both
indicators turn off at the same time. If you did see the
above situation, replace the volumetric board.
1
Click
"Service"
"System Test", and then click
the Vacuum Of VC, Pressure Of VC and Pressure Of
PC buttons on the screen to see if the error can be
cleared.
2
If the error cannot be cleared, check if the data
board is working properly; if not, resolve the problem
of data board first.
1)
2
Pressure
Abnormal
buildup fails
pressure
2)
3
Check if the detection channels of the vacuum and
pressure chambers are connected reversely; if yes,
Vacuum
buildup fails
4 If the data board and detection channels
connection errors are excluded, check if the wires
connecting the volumetric board, the drive board and
the data board are loose or damaged; if the wires are
loose, replug them; if they are damaged, replace
them.
5
If the wires are ok, replace the volumetric board.
6-34
Hardware System
6.8.2 Troubleshooting
The phenomenon of sample compartment connection board error is the analyzer does not
respond to closing operation. Clear the error per the following procedure:
1 Check if the drive board is working properly, if not, handle the problem of the drive board first.
2 Check if the wire of the sample compartment connection board (including J8 of drive board, J1
and the transfer socket of sample compartment connection board) is loose or damaged, if so,
replug or replace the wire.
3 If the problem mentioned in step 1 can be excluded, disassemble the board, check if there are
fluid spills in the switch; if yes, replace the board.
4 If not, replace the drive board.
6-35
Hardware System
6.9.2 Structure
The indicator board consists of indicators of three colors- red, yellow and green, their control
circuits and the drive circuit of buzzer. The indicator board does not need to be adjusted.
6.9.3 Troubleshooting
No.
Type
Description
Troubleshooting Methods
There are 7 LEDs for an indicator of one color. If the
indicator is dim, that means some of the 7 LEDs are
damaged. Disassemble the indicator board, see if the
The indicator is
dim
Indicator
indicator
cannot turn on
The buzzer
does not beep
2
Buzzer
when the
analyzer sends
alarm
6-36
Servicing
7.1 General
You can service the BC-3600 and BC-3300 as per Section 7.2 7.21. For the repairing with
verification, you must follow the procedures strictly to verify the maintenance.
7-1
Servicing
Make sure the door of sample compartment is closed when opening the
Front Panel, or it may cause damage on the sample compartment and the
Front Panel.
Installation: Install the Front Panel according to the steps stated above in reverse order.
Verification:
Pull the Front Panel to check whether its locked tightly;
Power on the analyzer and verify your replacement.
7-2
Servicing
Installation: Install the Left Door according to the steps stated above in reverse order.
Verification: Pull the Left Door to check whether its locked tightly.
7-3
Servicing
7-4
Servicing
Installation: Install the Top Cover according to the steps stated above in reverse order.
Verification: Check Whether the Top Cover is installed properly.
Turn off the analyzer and unplug the power cord from the wall outlet;
2.
Open the Front Panel as per 7.2.1, unplug all cables connected between the Front Panel
and the Main unit;
3.
4.
Use a sharp nose pliers to straighten the forelock on the hinge and then pull it out;
5.
Lift the Front Panel Assembly for about 5mm, and then take out the assembly.
7-5
Servicing
7.3 Replacing
the
Hardware
parts
and
Cable
connection
7.3.1 Replacing the Data board
Purpose: Follow the procedures to replace the data board as needed.
Tools: 107 cross-headed screwdriver
Removal:
1. Power off the analyzer and unplug the power cord from the wall outlet;
2. Open the left door as per 7.2.2;
3. Unplug all cables on the power driver board;
4. Use the 107 cross-headed screwdriver to unscrew the 7 cross-headed screw
driver on power driver board(see Figure 7.7);
5. Take out the data board.
7-6
Servicing
7-7
Servicing
7-8
Servicing
7-9
Servicing
7-10
Servicing
7-11
Servicing
7-12
Servicing
driver board is correct. Check Whether the Pressure and Vacuum sensor are
connected correctly;
2. Turn on the analyzer. Check whether the background is within range, if not,
please do the troubleshooting needed.
7-13
Servicing
Make sure the sample probe is always located on the upper position during
7-14
Servicing
the disassembly.
Installation: Install the Sample compartment connection board according to the steps stated
above in reverse order
Verification:
1. Check whether the cables are connected correctly between the Sample
compartment connection board and the Power driver board;
2. Turn on the analyzer and check whether the sample compartment is working
normally.
7-15
Servicing
Figure 7-16 Removing the Indicator Board
Installation: Install the indicator board according to the steps stated above in reverse order.
Verification:
1.
Check whether the cable connection between the Indicator board and the Data
board is correct;
2.
Turn on the analyzer. Check whether the indicator can show red, yellow and green
colors correctly when error message displayed, and if the buzzer is working
normally.
7-16
Servicing
Figure 7-17 Removing the Power Supply Assembly
Installation:
Verification:
1. Check whether the power connections meet the requirement;
2. Check whether the indicators on the data board and power driver board are on
good condition;
3. Check whether the monitoring voltages are within range in Self-test screen.
7-17
Servicing
Figure 7-18 Removing the Displaying Assembly
Installation: Install the Display assembly according the steps stated above in reverse order.
Verification:
1. Check whether all components are installed and fixed in place; Check whether
the cables are connected correctly;
2. Start up the analyzer and check the displaying of the screen.
Servicing
the cables are connected correctly;
2. Start up the analyzer and check the touching and displaying of the screen.
7-19
Servicing
7-20
Servicing
Please empty the liquid system before replacing the valve, otherwise the
reagents
might
leak
out
of
instrument
and
cause
the
biological
contamination.
Installation: The installation procedures are the reverse order of step 1~8, during the
installation, the direction of the valve month should be in accordance with previous one.
Verification:
1. Check if the parts are assembled properly;
2. Make sure the tube connection and power cable connection are correct;
3. Turn on the instrument, and press Menu in counting screen to pop-up the
system menu, choose service-> Valve test to test the related valve.
Servicing
assembly.
4. Open the top panel(as per section 7.2.4);
5. Unplug the all the tubes connected with the waste pump, please dont disassemble
the fluid pump protecting plate;
6. Disconnect the cable connector between the fluidic diaphragm and electric
diaphragm
7. As following Figure shows, Use the 107 cross-headed screwdriver to remove the
four M3 sunk screws and four spacers.
8. Take out the waste pump assembly.
Please empty the liquid system before replacing the pump assembly,
otherwise the reagents might leak out of instrument and cause the biological
contamination.
Installation: The installation procedures are the reverse order of step 1~8, during the
installation, the direction of the pump month should be in accordance with previous one.
Verification:
1. Check if the parts are assembled properly or not;
2. Make sure the tube connection and power cable connection are
correct;
3. Turn on the instrument, and press Menu in counting screen to
pop-up the system menu, choose service-> system test to
access the Vacuum Test to test the vacuum.
Servicing
7-23
Servicing
Installation: The installation procedures are the reverse order of step 1~9, during the
installation, the direction of the pump and chamber assembly and connection should be in
accordance with previous one.
Verification:
1. Check if the parts are assembled properly or not;
2. Make sure the tube connection and power cable connection are
correct;
3. Turn on the instrument, and press Menu in counting screen to
pop-up the system menu, choose service-> system test to
access the Pressure Test to test the pressure.
7-24
Servicing
2 Pad
3 Hoop
Installation: The installation procedures are the reverse order of step 1~5, during the
installation, the direction of the pump and chamber assembly and connection should be
in accordance with previous one.
Verification:
7-25
Servicing
7-26
Servicing
6Filter assembly
Installation: The installation procedures are the reverse order of step 1~5.
Verification:
1. Check if the parts are assembled properly or not;
2. Make sure the tube connection and power cable connection are correct;
3. Turn on the instrument, go to counting screen, unplug the rinse cap assembly,
dont let the rinse go into the instrument. Count, observe if instrument could
7-27
Servicing
give the alarm. If it could reflect the real situation, that means the sensor
works well.
All the samples, controls, calibrators, reagents, wastes and areas contacted
them are potentially biohazardous. Wear proper personal protective
equipment (e.g. gloves, lab coat, etc.) and follow safe laboratory procedures
when handling them and the contacted areas in the laboratory.
7-28
Servicing
2.
Servicing
Please adjust the sample probe position, before disassemble the shielding
box, make sure the sample probe is out of the shielding box to prevent the
probe is bended or hurt the operator.
1 Shielding box
Installation: The installation procedures are the reverse order of step 1~5, please make
sure not to press the liquid tube while cover the shielding box.
Verification:
1. Check if the parts are assembled properly or not;
2. Turn on the instrument to verify.
Servicing
Installation: The installation procedures are the reverse order of step 1~9, during
installation, hang the assembly on the four screws via the gourd hole, tighten the screws.
Then connect and arrange tubes. Make sure it s the same with previous, and never make
any tubes bended and pressed.
Verification:
1. Check if the parts are assembled properly or not;
2. Turn on the instrument to verify.
Servicing
Removal:
1. Empty the liquid system;
2. Power off the instrument and unplug the power cable.
3. Open the front panel assembly(as per section 7.2.1);
4. Open the right side panel(as per section 7.2.3)
5. Open the top panel(as per section 7.2.4);
6. Disassemble the shielding box(as per section 7.9.1);
7. Unplug the tubes and cable connectors on the counting bath;
8. As following Figure shows. Use the 107 cross-headed screwdriver to remove
the two M36 pan head screws fixing the counting bath, and remove the
counting bath cover board;
9. Take out the WBC counting bath.
Installation: The installation procedures are the reverse order of step 1~9, during
installation, pay attention to the direction of the counting bath, Make sure it s the same
with previous, and never make any tubes bended and pressed.
Verification:
1. Check if the parts are assembled properly or not;
2. Turn on the instrument to verify.
Servicing
Removal:
1. Disassemble the WBC assembly(as per section 7.9.3);
2. Use the cross-headed screwdriver to remove the two M2X10 screws,
disassemble the HGB assembly from counting bath.
3 --- O gasket 61
Servicing
9.
the two M36 pan head screws fixing the counting bath, and remove the
counting bath cover board;
Use cross-headed screwdriver to remove the ground cable, take out the WBC
counting bath.
Installation: The installation procedures are the reverse order of step 1~9, during
installation, pay attention to the direction of the counting bath, Make sure it s the same
with previous, and never make any tubes bended and pressed.
Verification:
1. Check if the parts are assembled properly or not;
2. Turn on the instrument to verify.
7-34
Servicing
2 --- O gasket 61
Servicing
the M3 pan head screws, remove the gasket, then take out the 10ml syringe
assembly or dual-syringe assembly.
Please empty the liquid system, before replacing the syringe assembly.
Otherwise, itll cause reagent leak or biological contamination. The syringe
assembly is a little heavy, during replacement, please support the syringe
assembly by hand, to prevent it drops and hurt people or instrument.
3 gasket
Installation: The installation procedures are the reverse order of disassembly steps
1~7. During installation, please make sure the connection and arrangement of the
syringe assembly tubes are same with previous.
Verification:
1. Check if the parts are assembled properly or not;
2. Make sure the tube connection and power cable connection are correct;
3. Turn on the instrument to verify.
7-36
Servicing
During installation, please care about the probe, to prevent the pricks. After
installation, please recalibrate the horizontal and vertical position.
7-37
Servicing
of
of
WBC
bath
sample
dispensing position
RBC
bath
sample
dispensing position
Figure 7-36 The screen to adjust the sample probe and wipe block
2. Adjust the wipe block:
For closed-reagent system: First, open the front panel(At this time, itll show
front panel is open error message in screen, to take care of it after
adjustment), see Figure-6B, Disassemble the tube baffle, remove the wipe
block, and assemble the positioning calibration fixture of sample probe on the
wipe block supporter by probe wipe fixing pin; Press wipe block position in
Y-direction motor as Figure 7-36 shows, then press start button, after
initialization, press up or down button to adjust the positioning calibration
fixture of sample probe, make its bottom is in the same level with sample
needle-point, see Figure-6C ; Then press save to save the setting; Remove
the fixture, and assemble the wipe block and probe wipe fixing pin, tighten
tube baffle to finish adjustment.
For the open-reagent system: open the front panel, remove the wipe block, and
assemble the positioning calibration fixture of sample probe on the wipe block
supporter by probe wipe fixing pin, the adjustment steps are same with above,
then remove the fixture, and assemble the wipe block to finish the adjustment.
7-38
Servicing
Tube baffle
Figure 7-38 Sample probe is in the same level with the wipe block
3.
Adjust WBC bath injection position: First, disassemble the shielding box, then
remove counting bath diaphragm as Figure 7-39 shows, Press WBC bath in
X-direction motor as Figure-6A shows. Then press start, press right to
move the sample probe to the right side, then place the WBC/RBC bath
calibration fixture properly and stably on the WBC bath as Figure 7-40 shows,
Press lift button in the software screen to move the probe just into the
aperture of fixture, then press save.
7-39
Servicing
Counting bath
diaphragm
Adjust the RBC bath injection position: The same with above procedures,
Press RBC bath in X-direction motor to adjust the RBC bath injection
position and save the setting as Figure-6F shows.
7-40
Servicing
5.
6.
7.
All the samples, controls, calibrators, reagents, wastes and areas contacted
them are potentially biohazardous. Wear proper personal protective
equipment (e.g. gloves, lab coat, etc.) and follow safe laboratory procedures
when handling them and the contacted areas in the laboratory.
Servicing
socket screws, then take out the vertical movement assembly in front.
2 slide block
7-42
Servicing
Installation: The installation procedures are the reverse order of disassembly, before
tightening the two Allen type stock screws on slide block, move the horizontal part to
right side, and keep it is closed with the end face of slide block, then tighten the crews.
After installation, please recalibrate the position of sample probe.
Verification:
1. Check if the parts are assembled properly or not;
2. Turn on the instrument to verify.
During adjustment, please wait for the Menu to become the normal ground
color before operation, otherwise, the system is busy, please try again
later warning message will pop-up;
Please make sure the tube baffle is installed properly, otherwise there is a
risk to happen interference;
After counting bath diaphragm installation, please make sure the counting
bath diaphragm is not crimped.
7-43
Servicing
2 Fluidic
assembly
tube
support
Servicing
6.
All the samples, controls, calibrators, reagents, wastes and areas contacted
them are potentially biohazardous. Wear proper personal protective
equipment (e.g. gloves, lab coat, etc.) and follow safe laboratory procedures
when handling them and the contacted areas in the laboratory.
Servicing
3.
Pull the probe wipe fixing pin downward by hand as following Figure shows;
7-46
Servicing
All the samples, controls, calibrators, reagents, wastes and areas contacted
them are potentially biohazardous. Wear proper personal protective
equipment (e.g. gloves, lab coat, etc.) and follow safe laboratory procedures
when handling them and the contacted areas in the laboratory.
Servicing
1.
2.
3.
4.
5.
6.
7.
2 front panel
3 M3X8 screw
During disassembly and installation, please keep the sample probe always in
upper position.
Installation:
7-48
Servicing
1.
2 Door supporter
3 M3x8 screw
Installation:
7-49
Servicing
1. When disassembling the sample compartment door separately, install the door on the
assembly, then slightly screw the four M3x8 screws to fix the door, not too tight;
2. Close the front panel, move the door, make the upper gap and side gap almost same;
3. Open the front panel, make sure the compartment door not to be implicated;(please
hold the door by your hand)
4. Tighten the four M3x8 screws to finish the installation and adjustment;
5. When replacing the whole sample compartment assembly, loose the two M3x16
stock head screws fixing the door supporter;
6. Repeat the step 1 to step3;
7. Tighten the two M3x16 stock head screws and four M3x8 screws to finish the
installation and adjustment.
7-50
Servicing
Installation: Insert the fixture of tube holder adapter to corresponding card slot, and
tighten the M4x12 socket head screws.
Verification: Make sure all the parts are assembled properly.
7-51
Servicing
2 screw
Locate the tube baffle as the position of screws, tighten the two screws.
Make sure all the parts are assembled properly.
7-52
Servicing
Servicing
1 Driver motor
3 M3x5screw
3 supporter
7-54
Servicing
Figure 7-55 Disassemble the flanged deep-slot ball bearing in left side
1 flanged deep-slot ball bearing
5x14x3.5
2. Disassemble the flanged deep-slot ball bearing in left side(with motor). Use
the cross-headed screwdriver to loose the four M38 pan head screws to
remove the synchronous belt;
3. Use the 2.5mm hex wrench to loose the two M3x12 screws to remove the
big band wheel;
4. Use cross-head driver to loose the two M3x8 small pan head screws,
remove the right side flanged deep-slot ball bearing.
7-55
Servicing
Figure 7-56 Disassemble the right side flanged deep-slot ball bearing
1synchronous belt
Servicing
4.
As following Figure shows, Use the 2.5mm hex wrench to remove two M36
Allen type socket screws, take out the start key;
7-57
Servicing
2 micro switch
3 Press Button
Installation: Installation procedure is reverse steps to disassemble.
Verification: No stuck with press button, meantime, check the gap between button and
panel, make sure its consistent.
7-58
Servicing
2Tubing Support-bracket
7-59
Servicing
2 Front board
7-60
Servicing
Servicing
All the samples, controls, calibrators, reagents, wastes and areas contacted
them are potentially biohazardous. Wear proper personal protective
equipment (e.g. gloves, lab coat, etc.) and follow safe laboratory procedures
when handling them and the contacted areas in the laboratory.
The reagents are irritating to eyes, skin and diaphragm. Wear proper
personal protective equipment (e.g. gloves, lab coat, etc.) and follow safe
laboratory procedures when handling them in the laboratory.
If the reagents accidentally spill on your skin, wash them off with plenty of
water and if necessary, go see a doctor; if the reagents accidentally spill into
your eyes, wash them off with plenty of water and immediately go see a
doctor.
When loose the Cap connecter, and be careful with left liquid drops on the
instrument or table.
Please tighten the reagent cap in case of the reagent contaminated when the
reagent and analyzer was connected.
7-62
Servicing
7-63
Servicing
Figure 7-64 WBC counting bath and HGB assembly (Right panel)
Motor Type
Position
Application
Step motor
Horizontal Movement
Assembly
Step motor
Vertical Movement
Assembly
Step motor
Sampling
Assembly
Material Description
Home-made three-way
electromagnetic valve
service kit
7-64
Servicing
1. Empty fluidics and shut down the analyzer
Home-made two-way
electromagnetic valve
service kit
Volumetric Tubing
Assembly
volumetric tube
4 Set up the volume of the volumetric tubing at the
corresponding screen
5 Monitor the background information.
6 Calibrate in the whole-blood mode
7 Calibrate in the predilute mode
Filter
N/A
6.
7.
8.
9.
3.
Servicing
4.
5.
6.
7.
8.
1.
2.
3.
Aperture sensor
(D80um)
4.
5.
6.
7.
8.
9.
7-66
Servicing
verify the result according to the specifications in the
PRS
9. Test repeatability using normal-level control in the
whole-blood mode and predilute mode
1 Empty fluidics and shut down the analyzer. Replace
the bath, and then start up the analyzer according to
standard procedures. Make sure the tubes are
properly connected and there is no leakage
2 Perform gain calibration
3 Verify the MCV values, as well as RBC histogram
after gain calibration
4 Monitor the background information
(without aperture)
10
(without HGB)
11
7-67
Servicing
there is no leakage
3 Perform gain calibration
4 Verify the HGB and MCV values, as well as the peak
values in the WBC histogram after gain calibration
5 Monitor the background information
6 Calibrate in the whole-blood mode
7 Run the calibrator after finishing calibration, and
verify the result according to the specifications in the
PRS
8
Calibrate in the predilute mode
9
Run the calibrator after finishing calibration, and
verify the result according to the specifications in the
PRS
1 Empty fluidics and shut down the analyzer
2 Replace the syringe and start up the analyzer
according to standard procedures
3 Make sure the tubes are connected properly and
there is no leakage
4 Calibrate in the whole-blood mode
5 Run the calibrator after finishing calibration, and
12
13
100L
assembly
syringe
service
7-68
Servicing
8 Test repeatability using the normal-level control in the
whole-blood mode
9 Test repeatability using the normal-level control in the
predilute mode
1 Empty fluidics and shut down the analyzer. Replace
the syringe, and then start up the analyzer according
to standard procedures
2 Make sure the tubes are connected properly and
there is no leakage
3 Calibrate in the whole-blood mode
4 Run the calibrator after finishing calibration, and
verify the result according to the specifications in the
14
PRS
5
Calibrate in the predilute mode
6 Run the calibrator after finishing calibration, and
verify the result according to the specifications in the
PRS
7 Test repeatability using the normal-level control in the
whole-blood mode
8 Test repeatability using the normal-level control in the
predilute mode
1 Empty fluidics and shut down the analyzer
2 Replace the isolation chamber, and then start up the
analyzer according to standard procedures. Make
15
Isolation chamber
16
PRS
6
Calibrate in the predilute mode
7 Run the calibrator after finishing calibration, and
verify the result according to the specifications in the
PRS
8 Test repeatability using the normal-level control in the
whole-blood mode
9 Test repeatability using the normal-level control in the
predilute mode
7-69
Servicing
1 Empty fluidics and shut down the analyzer
2 Replace the probe wipe and start up the analyzer
according to standard procedures
3 Make sure there is no leakage in the new probe wipe
4 Calibrate in the whole-blood mode
5 Run the calibrator after finishing calibration, and
verify the result according to the specifications in the
17
Probe Wipe
PRS
6
Calibrate in the predilute mode
7 Run the calibrator after finishing calibration, and
verify the result according to the specifications in the
PRS
8 Test repeatability using the normal-level control in the
whole-blood mode
9 Test repeatability using the normal-level control in the
predilute mode
1 Empty fluidics and shut down the analyzer
2 Replace the probe and start up the analyzer
according to standard procedures
3 Refix the position of the probe wipe
4 Calibrate in the whole-blood mode
5 Run the calibrator after finishing calibration, and
verify the result according to the specifications in the
18
Piercing probe
PRS
6
Calibrate in the predilute mode
7 Run the calibrator after finishing calibration, and
verify the result according to the specifications in the
PRS
8 Test repeatability using the normal-level control in the
whole-blood mode
9 Test repeatability using the normal-level control in the
predilute mode
1 Perform rinse priming, and make sure that the rinse
19
20
21
Servicing
1 Remove the BNC connector of the waste cap
22
the waste
23
24
25
26
27
28
pipe.1/16"X1/8",
N/A
1 Empty fluidics and shut down the analyzer
2 Replace the pipe and start up the analyzer according
to standard procedures
1 Empty fluidics and shut down the analyzer
2 Replace the pipe and start up the analyzer according
to standard procedures
29
1/32"X1/16",30 (0.78
to standard procedures
30
0.066"X0.098"X (1.5
to standard procedures
V4 and V12)
Rubber pipe OD3mm
31
to standard procedures
32
1 Export parameters
(with software)
2 Restore parameters
1 Export parameters
33
Data board
Servicing
1 Export parameters
34
Driver board
35
Power board
36
Interface board
37
38
39
40
Indicator Board
Sample
compartment
connection board
TR60-D
recorder
driver
board
41
Touch Screen
42
Inverter
43
Photocoupler
its
Servicing
connecting
cables
(the
44
HGB assembly
45
Recorder
is OK
1 Adjust the interval between the compartment and the
cover
46
Sample
compartment
assembly
47
48
49
Sampling assembly
Servicing
PRS
7 Test repeatability using the normal-level control in the
whole-blood mode
8 Test repeatability using the normal-level control in the
predilute mode
1 Fix the position of the sample probe wipe
2 Adjust the position of the sample probe in the
WBC/RBC bath and the sample compartment
3 Calibrate in the whole-blood mode
4 Run the calibrator after finishing calibration, and
verify the result according to the specifications in the
PRS
50
5
Calibrate in the predilute mode
6 Run the calibrator after finishing calibration, and
verify the result according to the specifications in the
PRS
7 Test repeatability using the normal-level control in the
whole-blood mode
8 Test repeatability using the normal-level control in the
predilute mode
1 Empty fluidics and shut down the analyzer
51
Fluidic
Pipe
Bracket
Assembly
up
the
analyzer
according
to
standard
procedures
2 Make sure the tubes are connected properly and
there is no leakage
3 Remove bubbles in the 100ul syringe
4 Calibrate in the whole-blood mode
5 Run the calibrator after finishing calibration, and
52
53
Double
Assembly
Syringe
Drive
up
the
analyzer
according
to
standard
Servicing
procedures
2 Make sure the tubes are connected properly and
there is no leakage
3 Remove bubbles in the 100ul syringe
4 Calibrate in the whole-blood mode
5 Run the calibrator after finishing calibration, and
verify the result according to the specifications in the
PRS
6
Calibrate in the predilute mode
7 Run the calibrator after finishing calibration, and
verify the result according to the specifications in the
PRS
8 Test repeatability using the normal-level control in the
whole-blood mode
9 Test repeatability using the normal-level control in the
predilute mode
1 Empty fluidics first. Replace the syringe, and then
start
up
the
analyzer
according
to
standard
procedures
2 Make sure the tubes are connected properly and
there is no leakage
3 Calibrate in the whole-blood mode
4 Run the calibrator after finishing calibration, and
verify the result according to the specifications in the
54
PRS
5
Calibrate in the predilute mode
6 Run the calibrator after finishing calibration, and
verify the result according to the specifications in the
PRS
7 Test repeatability using the normal-level control in the
whole-blood mode
8 Test repeatability using the normal-level control in the
predilute mode
1 Empty fluidics first. Replace the syringe, and then
start
up
the
analyzer
according
to
standard
procedures
2 Make sure the tubes are connected properly and
55
Single
Assembly
Syringe
Drive
there is no leakage
3 Calibrate in the whole-blood mode
4 Run the calibrator after finishing calibration, and
verify the result according to the specifications in the
PRS
5
Calibrate in the predilute mode
6 Run the calibrator after finishing calibration, and
7-75
Servicing
verify the result according to the specifications in the
PRS
7 Test repeatability using the normal-level control in the
whole-blood mode
8 Test repeatability using the normal-level control in the
predilute mode
1 Start up the analyzer and make sure the screen
56
Screen assembly
57
Adapter Assembly 1
N/A
58
Adapter Assembly 2
N/A
display is OK
59
60
Aspirate Key
61
Front
Cover
Status
Detection Assembly
62
up
the
procedures.
analyzer
Click
the
according
"Zap"
to
button
standard
at
the
Sample
63
Micro-switch
Compartment
Switching
Cable
64
1 Start
65
the
analyzer
according
to
standard
up
the
analyzer
according
to
standard
up
up
the
analyzer
according
to
standard
7-76
Content of Maintenance
Every day
Every week
As needed
8-1
8.2.2 Calibration
Calibration is a procedure to standardize the analyzer by determining its deviation under
certain specified conditions. In order to get accurate sample analysis results, you should
calibrate the analyzer per the procedure below when necessary. See Chapter Using the
calibration programs in operation manual.
8-2
Figure 8-4 Comparison of well mixed sample and poorly mixed sample
5. Cap the tube well after each test of controls or calibrations to ensure their stability.
6. After mixing well, you need only to shake the controls or calibrations slightly before each
test.
7. After a group tests or being placed for more than 5mins, controls or calibrations should be
mixed as well as STEP 4 before they are use again.
8-3
8-4
Error Information
Error code
Error Name
Error code
0x30000200
0x30000603
0x30000621
chamber.
0x30000221
WBC clog
0x30000700
the X direction
Steps error occurs when
sampling assembly adjusts in
the Y direction
Sampling assembly is working.
Sampling assembly X motor
movement overtime
Sampling assembly action
forbidden
Sampling assembly Y motor
movement overtime
Sampling assembly action
forbidden
Sampling assembly Y motor
piercing error
ASP/LS syringe fails to find the
home position
0x30000701
tube)
0x30000227
RBC clog
0x30000702
0x30000703
tube)
0x30000229
0x3000022B
0x3000022C
0x3000022E
0x30000300
0x30000720
0x30000721
0x30000500
0x30000521
0x3000052A
0x30000320
0x30000321
0x30000322
0x30000528
0x30000323
Diluent expired
0x30000A01
0x30000324
Rinse expired
0x30000A02
0x30000325
Lyse expired
0x30000A03
9-1
software)
No lyse (reported by
software)
0x30000523
0x30000525
Error Information
DIL syringe fails to find the
0x30000301
0x30000A05
0x30000326
0x30000540
0x30000327
0x30000328
home position.
0x30000329
0x3000032A
0x3000032B
0x30000541
0x30000542
0x30000543
0x30000544
0x30000545
0x30000400
0x30000B00
0x30000403
0x30000B02
0x30000420
0x30000C00
0x30000421
Recorder overheat
0x30000C02
0x30000423
0x30000C03
0x30000600
0x30000D00
0x30000602
0x30000580
0x30000620
Background abnormal
0x30000A00
movement error
Sample compartment
micro-switch error
Sample compartment is not in
the close position
Sample compartment motor is
working.
Sample compartment action
overtime
0x30000601
Causes analysis
Troubleshooting
9-2
Error Information
1. The vacuum pump is abnormal, check if the pump is
working when building the pressure and whether there
is air leakage in the pump.
When the time for
Building
vacuum
error
vacuum pump.
Vacuum is
out of the
range
Building
pressure is
not allowed
in the
vacuum
Instruction collision
when building pressure
chamber.
1. The pressure pump is abnormal, check if the pump
is working when building the pressure and whether air
leakage exists in the pump and pressure filter.
When the time for
Building
chamber.
pressure
error
out of range
Error Information
3. Check if there is air leakage in the tubing and valve
connected to the pressure chamber or pressure pump.
4. Check whether the pressure sensor and its tubing
on the volumetric board are normal.
5. If the problem persists, consider to change the
volumetric board or driver board.
Building
pressure is
not allowed
in the
pressure
Instruction collision
when building pressure
chamber.
Causes
Troubleshooting
analysis
No rinse (hardware
status checked
reported)
in assigned time
is empty.
No rinse (reported by
software)
No diluent (reported by
software)
No lyse (reported by
software)
The residual
amount is lower
than 5%.
The residual
amount is lower
than 5%.
The residual
amount is lower
than 5%.
Error Information
2. Take the dobber out of the waste container to
see if the dobber drops reliably.
Expiration date
Diluent expired
expiration date.
range.
Expiration date
Rinse expired
expiration date.
range.
Expiration date
Lyse expired
expiration date.
range.
Expiration date
Reagent kit expired
expiration date.
range.
Causes analysis
Troubleshooting
X direction motor
photocoupler error, or the
Steps error
occurs when
sampling
assembly
Adjust again
adjusts in the X
direction
Steps error
occurs when
sampling
assembly
Adjust again
adjusts in the Y
direction
Sampling
assembly is
working.
9-5
Error Information
Sampling
assembly X
motor
movement
overtime
overtime
Sampling
assembly
action
forbidden
Sampling
assembly Y
motor
movement
overtime
overtime
Sampling
assembly
action
forbidden
Sampling
assembly Y
motor piercing
error
area.
is working.
action failure 1
action failure 2
allowed by
Error Information
ASP/LS motor.
ASP/LS motor
movement
overtime
DIL motor is
working.
photocoupler is blocked.
Aspiration and
draining action
1 is not allowed
by DIL motor.
Aspiration and
draining action
2 is not allowed
by DIL motor.
DIL motor
movement
overtime
photocoupler is blocked.
X motor actual movement
overtime
9-7
Error Information
Photocoupler error of the
close position of the sample
Sample
compartment
movement error
compartment
micro-switch
error
placed.
Sample
compartment is
not in the close
position
Sample
compartment
motor is
working.
not close.
Control instruction collision of
the sample compartment
motor
Sample
compartment
movement
overtime
Recorder out of
paper
Recorder
overheat
overheat
Recorder fails
to respond.
Front cover is
opened.
damaged.
Causes analysis
56V voltage
abnormal
out of range
Troubleshooting
1. Check whether the 56V test point on the data board
is normal.
2. Check whether the analogue +12V test point on the
9-8
Error Information
data board is normal.
3. Remove J4 from the data board; check whether the
analogue 12V voltage from the power supply is
normal.
4. Change the data board or power supply board
based on the checking results.
1. Check whether the analogue +12V test point on the
data board is normal.
12V
analogue
voltage
out of range
abnormal
-12V
analogue
voltage
out of range
abnormal
24V power
voltage
abnormal
board is normal.
The voltage detected is
out of range
12V power
voltage
abnormal
board is normal.
The voltage detected is
out of range
Driver board
5V voltage
abnormal
is normal.
The voltage detected is
out of range
Causes analysis
Troubleshooting
9-9
Error Information
1. Check whether the reagents are connected
correctly. Especially note that whether the waste is
connected to the reagent inlet.
2. Perform background counting after all the reagents
are changed.
3. If the problem persists, open the front cover and
Background
Background out of
abnormal
range
HGB blank
voltage is 4.50.1V.
voltage
abnormal
of [3.2V,4.9V]
HGB value
abnormal
voltage is 4.50.1V.
2. Check whether the fluid dispensing of WBC bath is
normal; ensure that there are no abnormal conditions
such as insufficient fluids and building bubbles.
3. If the problem persists after the above checking,
then change the HGB assembly.
1. Enter the maintenance screen, zap and flush for
photocoupler or the
count time is too
long
WBC bubbles
(liquid remains
in the
photocoupler or the
volumetric
Error Information
tube)
short.
The triggering time
of the first RBC
RBC clog
photocoupler or the
(liquid remains
in the
photocoupler or the
volumetric
tube)
short.
Causes analysis
Printer out of paper or
Printer out of
paper
placing
Other errors
of the printer
abnormal
Troubleshooting
Place in the printing paper again, trigger the printer to
go on printing (Different operations are used by
different models of the printers, see the printer
operator's manual for details).
Check whether the status of the printer is normal and
remove relevant errors. (see the printer operator's
manual for details)
Causes analysis
The temperature
detected by the
temperature sensor is
out of the operating
range.
Troubleshooting
1. Check whether the temperature shown by the
device matches the real temperature.
2. Check whether the cables and connectors of the
temperature sensor are normal.
3. If the problem persists, then change the driver
board.
Causes analysis
Troubleshooting
1. Check whether correct cable connections
Data
Abnormal connection
communication
or incorrect
error
communication setting
Error Information
Error Information
Observe the variation of the WBC histogram. If the peak of the histogram moves slightly to the
right, generally it is because of insufficient reaction, check whether the adding of reagents in
WBC bath is normal, or change for another batch of reagents. If the WBC histogram varies
seriouslyit is possibly caused by insufficient lyse, check the adding of reagents, and also
relevant factors such as the mixing up the WBC bath, liquid level of the front bath, bubbles in
the back bath and so on.
Error Information
1. Normal sample
Parameter result
Histogram
Histogram
9-14
Error Information
3. Hemolytic anemia
Parameter result
Histogram
Histogram
9-15
Error Information
Histogram
R3
Histogram
R2R3Rm
9-16
Error Information
Histogram
R2R3R4Rm
Histogram
R2R3Rm
9-17
Error Information
Histogram
R1R3Rm
Pm
Figure 9-13 Histogram of the chronic myelocytic leukemia sample during the treatment with
interference of NRBC
Histogram
Pm
Pl
Figure 9-14 Reason for leucopenia - Histogram with interference of RBC debris
9-18
Error Information
11. Thrombocytosis
Parameter result
Histogram
Histogram
R1R2R3Rm
9-19
Error Information
Histogram
14. Lymphocytosis
Parameter result
Histogram
R3
Pm
Figure 9-18Histogram of lymphocytosis sample
9-20
Error Information
15. Monocytosis
Parameter result
Histogram
R2R3Rm
9-21
Error Information
Figure 9-21
9-22
Error Information
Figure 9-22
When the background is clean, most part of the channels of background count is saturated
pulse formed by the small bubbles as shown in the above figure. Only a small quantity of
particles scatter everywhere in the pulse figure.
Error Information
Figure 9-24
Figure 9-25
In normal condition, the pulse width of WBC, RBC and PLT are generally consistent, but the
pulse peak of WBC is distributed unevenly, while the pulse heights of RBC are distributed
consistently, and the pulse peak of PLT is the lowest. When refer to the pulse spacing the
pulse distribution of WBC are sparse, while the RBC distribution is dense, the PLT is generally
scattered between other pulses.
9-24
Error Information
Figure 9-27
9-25
Error Information
Figure 9-29
Figure 9-30 PLT pulse when there is no fluid in the back bath
When there is no fluid at the back bath or when a lot of bubbles are aspirated, the RBC/PLT
signal baseline will disappear; in the meantime, the pulse will be fully saturated.
9-26
10
A
Appendices
Please provide the code and name of the MINDRAY spare parts listed in this manual when you
order and purchase spare parts from MINDRAY. This will help us offer you the spare parts you
need as soon as possible. Choosing spare parts by MINDRAY will ensure the perfect working
state of you analyzer.
Description
MINDRAY
Remark
code/model
1
801-3007-00001-00
Data board
801-3007-00002-00
Driver board
801-3007-00003-00
801-3007-00004-00
Indicator board
801-3007-00005-00
801-3007-00006-00
801-3007-00007-00
Volumetric board
801-3007-00008-00
801-3007-00009-00
only applicable to
closed tube model
Description
MINDRAY
code/model
Touchscreen
801-3900-00037-00
801-3007-00010-00
Screen assembly
801-3007-00011-00
Recorder assembly
801-3007-00012-00
801-3007-00013-00
HGB assembly
801-3900-00041-00
7
8
9
10
801-3900-00061-00
Front cover door detect assembly
Photocoupler and connecting cable
801-3900-00039-00
801-3900-00040-00
801-3900-00059-00
A-1
Remark
Appendices
motor
11
Micro-switch
801-3007-00014-00
12
801-3900-00001-00
13
801-3007-00015-00
14
15
16
17
801-3900-00003-00
801-3900-00004-00
801-3900-00005-00
801-3900-00006-00
18
801-3007-00016-00
19
801-2800-00013-00
20
801-3110-00078-00
21
801-3900-00095-00
22
Sampling assembly
801-3007-00017-00
23
801-3007-00018-00
24
801-3007-00019-00
25
26
27
28
only applicable to
Probe wipe clamp (Open vial)
801-3900-00013-00
only applicable to
Probe wipe clamp (Closed tube)
801-3900-00014-00
801-3900-00015-00
29
801-3900-00054-00
30
801-3900-00053-00
31
10ml syringe
801-3900-00009-00
32
801-3900-00051-00
33
801-3900-00052-00
34
2.5ml syringe
801-3900-00007-00
37
38
39
801-3101-00002-00
36
35
801-3900-00008-00
801-3007-00020-00
801-3007-00021-00
801-3007-00022-00
801-3007-00023-00
A-2
only applicable to
closed tube model
only applicable to
closed tube model
only applicable to
closed tube model
only applicable to
closed tube model
Appendices
40
Adapter assembly 1
801-3007-00024-00
41
Adapter assembly2
801-3007-00025-00
42
801-3900-00096-00
43
44
45
801-3007-00026-00
801-3007-00027-00
801-3900-00094-00
46
801-3900-00046-00
47
801-3007-00028-00
48
801-3007-00029-00
49
801-2800-00018-00
801-3900-00020-00
51
801-3007-00030-00
52
801-3900-00022-00
53
801-3007-00031-00
54
801-3007-00032-00
55
801-3101-00047-00
56
801-3900-00024-00
57
801-3900-00010-00
58
Air filter
801-1805-00026-00
59
801-1805-00006-00
60
801-1805-00005-00
61
801-0030-00001-00
801-0030-00002-00
63
801-3007-00033-00
64
Tubing package
801-3900-00083-00
65
801-3900-00097-00
66
801-3900-00098-00
67
801-3900-00099-00
68
801-3900-00100-00
69
801-3900-00101-00
70
801-3900-00102-00
71
Tube barrier
50
only applicable to
801-3900-00103-00
A-3
Appendices
72
73
801-3900-00104-00
801-3900-00105-00
74
801-3900-00106-00
75
801-3900-00107-00
76
801-3900-00108-00
77
801-3900-00109-00
78
801-3900-00110-00
79
Cable package
801-3007-00034-00
80
Screw package
801-3007-00035-00
81
Connector package
801-3900-00092-00
82
Tools kit
801-3007-00036-00
83
801-3007-00037-00
84
85
86
87
801-3007-00038-00
801-3007-00039-00
801-3007-00040-00
801-3007-00043-00
only applicable to
open vial model
only applicable to
closed tube model
only applicable to
open vial model
only applicable to
closed tube model
Description
MINDRAY
Bidding
no.
code/model
corresponding to
appendix C
009-001367-00
(1)
009-001366-00
(2)
009-001368-00
(3)
volumetric board
3900-20-85357
(4)
009-001363-00
(5)
(5)
tube)
009-001417-00
009-001195-00
valve control
Pump
control
Connecting
wire
Connecting
10
009-001376-00
009-001373-00
wire
temperature sensor
of
3900-20-85347
A-4
(6)
(7)
(8)
(9)
Remark
Appendices
Connecting wire harness of
photocoupler signal (closed
11
tube)
009-001365-00
photocoupler
009-001412-00
Sample
13
compartment
wire
of
009-001375-00
data
(10)
(11)
(12)
(13)
14
3900-20-85342
15
009-001419-00
(14)
16
3900-20-85345
(15)
17
3900-20-85344
(16)
18
3900-20-85343
(17)
19
3900-20-85341
(18)
20
009-001364-00
(19)
opening
3900-20-85379
Connecting
22
wire
of
LCD
screen signal
009-001418-00
009-001369-00
assembly
Ground wire of the screen
24
backboard
Transferring
25
009-001374-00
wire
of
LCD
2800-20-28768
3900-21-85368
509B-10-05996
of national standards
(20)
(21)
(22)
(23)
(24)
(25)
/
Description
MINDRAY
code/model
1.
A30-000001---
2.
Tubing package
801-3900-00083-00
3.
only
Centrifugal tube (1.5ml)
A21-000013---
4.
A22-000005---
5.
A21-000012---
6.
Mindray
B30
controls
(high
0031-30-84473
0031-30-84476
level/3ml)
7.
Remark
level/3ml)
A-5
applicable
to
Appendices
8.
Mindray
B30
controls
(low
0031-30-84479
level/3ml)
9.
0031-30-84549
10.
A12-000099---
11.
Mindray
M-30PCFL
cyanide-free
lyse (150ml)
12.
Mindray
A11-000079---
M-30PCFL
cyanide-free
lyse (250ml)
13.
Mindray
A12-000103--M-30PCFLcyanide-free
lyse (500ml)
A12-000104---
14.
A12-000107---
15.
105-000385-00
A-6
Appendices
No.
Material name
MINDRAY code/model
Remark
801-3900-00013-00
only applicable
open vial model
801-3900-00014-00
only applicable to
closed tube model
801-3900-00015-00
only applicable to
closed tube model
Air filter
801-1805-00026-00
1
Probe wipe clamp (open vial)
2
3
4
B-1
to
Appendices
12
tube model;
4) The rest of the connections are the same for closed tube model and open vial model;
5) See Appendix A.3 for the details of the list of cable codes.
6) The electricity connection diagram of the analyzer is shown as follows.
C-1
Appendices
C-2
Appendices
Fluidic Diagram
D-1
Appendices
Function
2-way/3-way
3
3
3
3
V05
V06
V07
V08
V09
V10
V11
V13
2
2
2
3
V14
Control the washing of the WBC back bath together with V07
V15
Control the washing of the RBC back bath together with V08
V16
V17
V18
V19
2
2
2
2
pump
Function
Building pressure in the pressure chamber, generating bubbles and flushing
(GP)
Waste pump
Draining the vacuum chamber and building vacuum in the vacuum chamber;
(LP)
Draining the waste in the WBC bath, RBC bath and the probe wipe.
E-1
Appendices
Function
Aspirating and dispensing sample
Adding lyse to WBC bath
Adding diluents to the WBC bath and the RBC bath, cleaning the
sample probe and adding diluents to the probe wipe
E-2
Appendices
Tubing
T47
DILUNET
T48
T2
RINSE
J5-T20J6
T49
SV2
SV1
J3-T56J4
SV13
T3
SV4
SV7
SV5
C26
J9-T64J10
T34
GF3
SV3
C4
T31
C16
T14
T15
T35
GF4
T53
Rinse
container
SV6
T32
GF1
SV8
C15
C13
T13
T30
C3
T12
T33
T39
GF2
T54
Pressure
sensor
Pressure sensor
T50
T40
SPB
T85
T28
T68
T51
T79
T52
Volumetric
tube 1
C27
PC
T80
LF
C1
VC
C23
C24
T81
T83
RBC
bath
T88
T97
Probe wipe
C14
C22
T87
Rinse
detectin
g
sensor
WBC
bath
T82T84
C2
T67
C25
T66
SV14
SV15
T36
SV9
T11
T6
SV11
T10
T41
C18
T7
SV10
J1
C9
7
C2
8
C8 J19
T77
J21J22-T63-J24J23
Isolation
chamber 1
C11
Waste
interface
T99
C19
GF6
LP
T9
SV18
T70
T69
SV19
SV17
SV16
T29
T29
T27
T26
C7
Waste tank
C10
T78
T8
C17
T42
T43
GF5
C20
T38
J18-T62J20
T18
GP
T37
T86
T98
T22
T24
T25
C6
T23
C5
F-1
T21
Isolation
chamber 2
Lyse
bottl
e
Appendices
Position in the
code/model
fluidic chart
No.
Name
T1
M6G-020005---
A1
55
T2
M6G-020005---
A1
60
T3
M6G-020005---
A2
30
T4
M6G-020005---
B2
15
T5
M6G-020005---
B5
35
T6
M90-100071---
C1
160
T7
M90-100071---
C2
15
T8
M90-100071---
C1
50
T9
M90-100071---
C3
75
10
T10
M90-100071---
C1
15
11
T11
M90-100071---
C2
80
12
T12
3001-10-07069
B3
51
13
T13
3001-10-07069
B3
43
14
T14
3001-10-07069
B3
41
15
T15
3001-10-07069
B3
51
16
T16
M90-000025---
B3
38
17
T17
M90-000025---
C3
35
18
T18
M90-100071---
C3
45
19
T20
M90-100031---
A2
430
20
T21
M90-100071---
D4
120
21
T22
M90-100071---
D3
30
22
T23
M90-000025---
D3
40
23
T24
M90-100071---
D2
30
24
T25
M90-000025---
D2
40
25
T26
M90-100071---
D2
30
26
T27
M90-000025---
D2
160
27
T28
A21-000007---
C3
50
28
T29
M90-000025---
D1
90
29
T30
M90-100071---
B2
20
30
T31
M90-100071---
B2
20
31
T32
M90-100071---
B2
15
32
T33
M90-100071---
B2
15
33
T34
M90-100071---
B2
15
34
T35
M90-100071---
B2
15
35
T36
A21-000007---
C1
35
36
T37
M90-100071---
C5
20
37
T38
M90-100071---
C4
90
38
T39
M90-100071---
B5
300
39
T40
A21-000007---
C1
50
40
T41
A21-000007---
C1
30
F-2
Length (mm)
Appendices
41
T42
M90-100071---
C1
15
42
T43
M90-100071---
C1
15
43
T47
M90-100071---
A1
70
44
T48
M90-000025---
A4
280
45
T49
3001-10-07069
A5
400
46
T50
A21-000007---
C1
60
47
T51
A21-000007---
C1
30
48
T52
M90-100071---
C1
80
49
T53
3001-10-07069
B4
460
50
T54
3001-10-07069
B3
480
51
T55
M90-100031---
B2
950
52
T56
M90-100031---
A5
610
53
T57
M90-000025---
C6
300
54
T58
A21-000002---
B5
300
55
T60
A21-000002---
B5
180
56
T61
3001-10-07069
B1
830
57
T62
M90-000026
C3
500
58
T63
M90-000026
C4
500
59
T64
M90-100031---
A4
75
60
T65
M90-100031---
B4
80
61
T66
M90-100071---
C4
210
62
T67
M90-100071---
C3
240
63
T68
M90-100071---
C2
660
64
T69
M90-100071---
D3
160
65
T70
M90-100071---
D4
160
66
T72
M6G-020007---
B2
500
67
T73
0040-10-32301
B4
60
68
T74
M90-100031---
B4
60
69
T75
M90-100031---
B4
105
70
T76
M6G-020005---
A2
25
71
T77
M90-100071---
C4
110
72
T78
M90-100071---
C4
50
73
T79
M90-100071---
C1
200
74
T80
M90-100071---
C3
210
75
T81
3001-10-07069
C4
25
76
T82
3001-10-07069
C4
25
77
T83
M90-100071---
C4
15
78
T84
M90-100071---
C4
15
79
T85
3001-10-07069
C3
25
80
T86
3001-10-07069
C3
25
81
T87
M90-100071---
C3
15
82
T88
M90-100071---
C3
15
83
T89
M90-100031---
C4
120
F-3
Appendices
84
T90
M90-100031---
C4
120
85
T92
M6G-020054---
B6
1500
86
T93
M6G-020054---
A5
1000
87
T95
M6G-020055---
D1
1500
88
T97
M90-000025---
C2
70
89
T98
M90-000025---
C2
85
90
T99
M90-100071---
C2
120
Position in the
code/model
fluidic chart
C1
M90-100028---
C3
C2
M90-100028---
C4
C3
M90-100028---
B3
C4
M90-100028---
B3
C5
M90-100065---
D3
C6
M90-100065---
D2
C7
M90-100065---
D2
C8
M90-100028-01
C3
C9
M90-100028-01
C3
10
C10
M90-100028-01
C4
11
C11
M90-100028-01
C4
12
C13
M90-100027-00
B2
13
C14
3001-10-07066
C1
14
C15
M90-100028-03
B2
15
C16
M90-100028-03
B2
16
C17
M90-100028-03
C1
17
C18
M90-100028-03
C1
18
C19
M90-100028-03
C1
19
C20
M90-100028-03
C5
20
C21
M90-100027---
A2
21
C22
M90-100100---
C3
22
C23
M90-100100---
C3
23
C24
M90-100100---
C4
24
C25
M90-100100---
C4
25
C26
M90-100100---
B2
26
C27
M90-100027---
C2
27
C28
M90-100027---
C2
No.
Name
F-4
Amount
Appendices
Name
MINDRAY code/model
Length (mm)
J1
082-000055-00
B2
20
J2
082-000055-00
B2
20
J3
082-000055-00
A5
20
J4
082-000055-00
A5
20
J5
082-000055-00
A2
20
J6
082-000055-00
A2
20
J7
082-000055-00
B4
20
J8
082-000055-00
B4
20
J9
082-000055-00
B4
20
10
J10
082-000055-00
B4
20
11
J11
082-000055-00
B4
20
12
J12
082-000055-00
B4
20
13
J13
M90-100071---
C4
50
14
J14
M90-100071---
C4
25
15
J15
M90-100071---
C4
50
16
J16
M90-100071---
C4
25
17
J17
M6G-020006---
C3
15
18
J18
M6G-020009---
C3
15
19
J19
M6G-020006---
C3
15
20
J20
M6G-020009---
C3
15
21
J21
M6G-020006---
C4
15
22
J22
M6G-020009---
C4
15
23
J23
M6G-020006---
C4
15
24
J24
M6G-020009---
C4
15
25
J25
2000-20-03314
B4
26
J26
2000-20-03314
B4
27
J27
2000-20-03314
B4
28
J28
2000-20-03314
C4
29
J29
2000-20-03314
C4
30
J30
2000-20-03314
C4
31
J31
2000-20-03314
C4
32
J32
0030-20-13339
B4
F-5
P/N
046-001623-00
1.0