Académique Documents
Professionnel Documents
Culture Documents
THROMBOEMBOLISM
intro
VTE includes
DVT
PE
Why in pregnancy
Hypercoagulatable state
Physiology
Venous statis
Increased factor viii, ix,x, fibrinogen
Px increase risk 6 folds (first trimes till
6w postpartum
C section increase 10-20 folds
Thrombophilia
History of-antiphospholipid synd,
antithrombin deficiency
Thromboembolism remains a
significant
But preventable cause of maternal
death
Risk scoring
Risk scoring for antenatal and
postnatal women for vte is probably
the most effective way of identifying
those at risk and requiring
prophylaxis treatment
The strategies
Creating awareness
prevention
Health clinic-identify very high risk pt
manage/refer
Hosp discharge- communicating with
health pt high risk or on treatment
Early detection
Awareness risk fact, sign and symptoms
Which thromboprophylaxis
LMWH is preferred-once daily and
safe self administered
Enoxaparine/clexane &
tinzaparin/innohep-efficacious and
safe-porcine
Heparin bd dose-given by medical
staff
fondaparinux
DVT
Important to note that half of all dvt
asymp
S&sm
Swelling one or both legs
Pain/tenderness while standing or
walking
Warmth in the skin affected leg
Leg fatigue
PE
Pe vary greatly depending how much
lung involved, size clot and comobid
S&sm
SOB sudden -active or rest
Chest pain-worse on exertion but not go
away when rest
Cough- bloody or blood streaked sputum
Wheezing
General wellbeing
S&sm DVT
S&sm PE
60% PE during postnatal
leaflet
Vte information leaflet
Heparin
???
Terima kasih