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BERI BERI Disease:

Symptoms of beriberi include weight loss,


emotional disturbances, impaired sensory
perception, weakness and pain in the
limbs, and periods of irregular heart rate.
Edema (swelling of bodily tissues) is
common. It may increase the amount of
lactic acid and pyruvic acid within the
blood. In advanced cases, the disease
may cause high-output cardiac failure and death.
Symptoms may occur concurrently with those of
Wernicke's encephalopathy, a primarily
neurological thiamine-deficiency related condition.
Beriberi is divided into three historical
classifications, a fourth form, gastrointestinal
beriberi, was recognized in 2004:
Dry beriberi specially affects the peripheral
nervous system
Wet beriberi specially affects the cardiovascular
system and other bodily systems
Infantile beriberi affects the children of malnourished mothers
Gastrointestinal beriberi affects the digestive system and other bodily systems

Glossitis Disease:

Glossitis could be
classified as a group of
tongue diseases or
gastrointestinal diseases.
[3] It may be primary, where there is no underlying cause, or secondary where it is
a sign or symptom of another condition.[2] It can be acute or chronic.[3] Generally
speaking, there are several clinical patterns of glossitis, some more common than
others.

Anemias
Iron deficiency anemia is mainly caused by blood loss, such as may occur during
menses or gastrointestinal hemorrhage. This often results in a depapilled, atrophic
glossitis, giving the tongue a bald and shiny appearance, along with pallor
(paleness) of the lips and other mucous membranes a tendency towards recurrent
oral ulceration,[24] and cheilosis (swelling of the lips).
Infections
Bacterial, viral or fungal infections can cause glossitis. Candida species are involved
in median rhomboid glossitis. Candida species also may be involved in creating a
more generalized glossitis with erythema, burning, and atrophy, e.g. erythematous
candidiasis e.g. as may occur in HIV/AIDS may involve the tongue giving glossitis
with depapillation.

Pellagra :
Pellagra is a systemic disease resulting from a nutritional deficiency particularly of
Niacin or Vitamin B3. The disease is marked by dermatitis, diarrhea, dementia and
death while it involves the skin, digestive system and the neurologic system.

Pellagra is classically
characterized with
four Ds which
denotes the part of
the body involved in
the disease. The
symptoms of Pellagra can occur daily and which may become severe while the
general symptoms differ from one person to another.
Skin is the first to be affected with a symptom of Pellagra. The skin is reddened associated with
scaling and may resemble severe sunburn which gradually turns dusky brown and red discoloration
after it has subsided.
Gastrointestinal symptoms in Pellagra are commonly characterized with diarrhea which is
experienced by majority of the patients.
Neurological symptoms may go unnoticed with initial symptoms of slight apathy and depression.

Anemia :

Anemia goes
undetected in many
people and
symptoms can be
minor. The symptoms
can be related to an
underlying cause or
the anemia itself.
Most commonly,
people with anemia
report feelings of
weakness, or fatigue,
general malaise, and
sometimes poor
concentration. They
may also report
dyspnea (shortness
of breath) on
exertion. In very
severe anemia, the
body may compensate for the lack of oxygen-carrying capability of the blood by
increasing cardiac output. The patient may have symptoms related to this, such as
palpitations, angina (if pre-existing heart disease is present), intermittent
claudication of the legs, and symptoms of heart failure. On examination, the signs
exhibited may include pallor (pale skin, lining mucosa, conjunctiva and nail beds),
but this is not a reliable sign. There may be signs of specific causes of anemia, e.g.,
koilonychia (in iron deficiency), jaundice (when anemia results from abnormal
break down of red blood cells in hemolytic anemia), bone deformities (found in
thalassemia major) or leg ulcers (seen in sickle-cell disease). In severe anemia,
there may be signs of a hyperdynamic circulation: tachycardia (a fast heart rate),
bounding pulse, flow murmurs, and cardiac ventricular hypertrophy (enlargement).
There may be signs of heart failure. Pica, the consumption of non-food items such
as ice, but also paper, wax, or grass, and even hair or dirt, may be a symptom of
iron deficiency, although it occurs often in those who have normal levels of
hemoglobin. Chronic anemia may result in behavioral disturbances in children as a
direct result of impaired neurological development in infants, and reduced academic
performance in children of school age. Restless legs syndrome is more common in
those with iron-deficiency anemia.

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