08B8E1 BIOPHARMACEUTICAL TECHNOLOGY

L T P C
3 0 0 3

UNIT – I INTRODUCTION 7

Pharmaceutical industry & development of drugs ; types of therapeutic agents and their uses ; economics
and regulatory aspects .

UNIT – II DRUG ACTION, METABOLISM AND PHARMACOKINETICS 9

Mechanism of drug action; physico-chemical principles of drug metabolism; radioactivity;

pharmacokinetics.

UNIT – III MANUFACTURE OF DRUGS, PROCESS

AND APPLICATIONS 7

Types of reaction process and special requirements for bulk drug manufacture of- Aspirin, penicillin,
streptomycin.

UNIT – IV PRINCIPLES OF DRUG MANUFACTURE 13

Compressed tablets; dry and wet granulation; slugging or direct compression; tablet presses; coating of
tablets; capsule preparation; oval liquids – vegetable drugs – topical applications; preservation of drugs;
analytical methods and other tests used in drug manufacture; packing techniques; quality management;
gmp.

UNIT – V BIOPHARMACEUTICALS 9

Various categories of therapeutics like vitamins, laxatives, analgesics, contraceptives, antibiotics,

hormones and biologicals: vaccines, monoclonal and polyclonal antibodies, growth hormones, cytokines.
.
Total : 45 Hours

TEXT BOOK

1. Leon Lachman tel al theory and Practice of Industrial Pharmacy, 3 Edition, Lea and Febiger,
1986.
2. Remington’s Pharmaceutical Sciences, Mark publishing and Co.

REFERENCES
1. Gareth Thomas. Medicinal Chemistry. An introduction. John Wiley. 2000.
2. Katzung B.G. Basic and Clinical Pharmacology, Prentice Hall of Intl. 1995.