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Pathophysiology:

Precipitating Factor: Predisposing Factor:


Early-Onset GENDER-Male
 Maternal Pyrexia (38°C)
 Difficult Delivery
 Primipara
 Maternal UTI
 Low Socio-economic Status
 Hazardous Uterine Environment

Mother will deliver the baby by Normal Spontaneous


Delivery while having UTI

The Amniotic fluid was drain first while the baby is inside the mother The baby don’t have body barriers Bacteria enters the body

Immune Body will respond Infection occurs

Pathogen enters the body Systemic Reaction

Neutrophils move in Increase neutrophils count Increase WBC count

Chemotaxic occurs Opsonization causes phagocytosis Monocytes kill pathogen


Systemic Reaction

Pro-Inflammatory Response Anti-Inflammatory Response

Vital Signs
Imbalance

Temperature:
38.1°C
Respiratory Rate:
61 cpm Increase activity of Fibrinolysis Monitoring, Analysis, and
Cardiac Rate: Response System
103 bpm
Decrease Fibrinolysis
SEPSIS

Platelet Destruction

Decrease of platelet count


SEPSIS

Initial Phase (1to3 days)

Body Compensates

Slow things down

Decrease Systemic Hypometabolism


Vascular
Resistance
Decrease Energy Expenditure

Decrease Cardiac Output

Decrease Oxygen Consumption Difficulty of Breathing

Vasoconstriction
Complications

Microorganisms
entering the body

Causing
infection

Pneumonia

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