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cbfe91a7fb007fe21bfecebffcee6beffa28039ff09f84fc2be02f0af867c0be05f0cf87fc17e09f
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8a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a002
8a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a002
8a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a002
8a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a002
8a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a002
8a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a002
8a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a002
8a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a002
8a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a002
8a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a002
8a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a002
8a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a002
8a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a002
8a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a002
8a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a002
8a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a002
8a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a002
8a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a002
8a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a002
8a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a00fffd9
}}\par}{\phpg\posx2678\pvpg\posy2165\absw7471\absh1487 \f10 \fs15 \cf0 \f10 \fs1
5 \cf0 tambahan.
\par}{\phpg\posx2678\pvpg\posy2165\absw7471\absh1487 \sl-292 \f10 \fs15 \cf0 \fi
679 Penggunaan bahan pemanis aspartam dalam formulasi tablet{\i efferves
cent} dimaksudkan
\par}{\phpg\posx2678\pvpg\posy2165\absw7471\absh1487 \sl-292 \f10 \fs15 \cf0 unt
uk menutupi rasa tablet yang kurang baik dan membuat produk menjadi lebih menari
k sehingga
\par}{\phpg\posx2678\pvpg\posy2165\absw7471\absh1487 \sl-292 \f10 \fs15 \cf0 aka
n diperoleh rasa manis tanpa rasa pahit atau{\i metalic}{\i aftertaste} (Pul
ungan, 2004). Penelitian ini
\par}{\phpg\posx2678\pvpg\posy2165\absw7471\absh1487 \sl-290 \f10 \fs15 \cf0 ber
tujuan untuk mendapatkan kadar pemanis aspartam yang menghasilkan tablet
effervescent
\par}{\phpg\posx2678\pvpg\posy2165\absw7471\absh1487 \sl-295 \f10 \fs15 \cf0 den
gan kualitas fisik yang baik serta rasa yang menyenangkan. \par
}
{\phpg\posx2678\pvpg\posy4311\absw7475\absh2831 \b \f10 \fs16 \cf0 \b \f10 \fs16
\cf0 METODE PENELITIAN
\par}{\phpg\posx2678\pvpg\posy4311\absw7475\absh2831 \sl-153 \par\b \f10 \fs16 \
cf0 {\fs15 Bahan }
\par}{\phpg\posx2678\pvpg\posy4311\absw7475\absh2831 \sl-292 \b \f10 \fs16 \cf0
\fi679 {\b0 \fs15 Bahan-bahan}{\b0 \fs15 yang}{\b0 \fs15 digunakan}{\b0 \fs1
5 pada}{\b0 \fs15 percobaan}{\b0 \fs15 ini}{\b0 \fs15 yaitu}{\b0 \fs15
simplisia}{\b0 \fs15 kering}{\b0 \fs15 akar}{\b0 \fs15 Ginseng }
\par}{\phpg\posx2678\pvpg\posy4311\absw7475\absh2831 \sl-292 \b \f10 \fs16 \cf0
{\b0 \fs15 Jawa}{\b0 \fs15 (}{\b0\i \fs15 Talinum}{\b0\i \fs15 paniculatum}{\b
0 \fs15 )}{\b0 \fs15 dari}{\b0 \fs15 daerah}{\b0 \fs15 Kaliurang-Yogyakarta,}
{\b0 \fs15 bahan}{\b0 \fs15 lain}{\b0 \fs15 yang}{\b0 \fs15 digunakan}{\b0 \
fs15 adalah }
\par}{\phpg\posx2678\pvpg\posy4311\absw7475\absh2831 \sl-290 \b \f10 \fs16 \cf0
{\b0 \fs15 asam}{\b0 \fs15 sitrat,}{\b0 \fs15 asam}{\b0 \fs15 tartrat,}{\b0 \
fs15 natrium}{\b0 \fs15 bikarbonat,}{\b0 \fs15 aspartam,}{\b0 \fs15 manitol,
}{\b0 \fs15 PEG}{\b0 \fs15 4000.}{\b0 \fs15 Kecuali}{\b0 \fs15 dinyatakan}{\
b0 \fs15 lain }
\par}{\phpg\posx2678\pvpg\posy4311\absw7475\absh2831 \sl-295 \b \f10 \fs16 \cf0
{\b0 \fs15 bahan}{\b0 \fs15 yang}{\b0 \fs15 digunakan}{\b0 \fs15 memiliki}{\b
0 \fs15 kualitas}{\b0 \fs15 farmasetis. }
\par}{\phpg\posx2678\pvpg\posy4311\absw7475\absh2831 \sl-290 \b \f10 \fs16 \cf0
{\fs15 Alat }
\par}{\phpg\posx2678\pvpg\posy4311\absw7475\absh2831 \sl-292 \b \f10 \fs16 \cf0
\fi679 {\b0 \fs15 Alat}{\b0 \fs15 yang}{\b0 \fs15 digunakan}{\b0 \fs15 pad
a}{\b0 \fs15 penelitian}{\b0 \fs15 ini}{\b0 \fs15 adalah}{\b0 \fs15 panc
i}{\b0 \fs15 infusa,}{\b0\i \fs15 Spray}{\b0\i \fs15 Drying}{\b0 \fs15 (
}{\b0\i \fs15 Buchi}{\b0\i \fs15 Mini }
\par}{\phpg\posx2678\pvpg\posy4311\absw7475\absh2831 \sl-292 \b \f10 \fs16 \cf0
{\b0\i \fs15 Spray}{\b0\i \fs15 Dryer}{\b0 \fs15 B-290),}{\b0 \fs15 neraca
}{\b0 \fs15 elektrik}{\b0 \fs15 (}{\b0\i \fs15 Metler}{\b0\i \fs15 Toledo}
{\b0 \fs15 type}{\b0 \fs15 PL303),}{\b0 \fs15 seperangkat}{\b0 \fs15 ala
t}{\b0 \fs15 gelas}{\b0 \fs15 (}{\b0\i \fs15 pyrex}{\b0 \fs15 ), }
\par}{\phpg\posx2678\pvpg\posy4311\absw7475\absh2831 \sl-290 \b \f10 \fs16 \cf0
{\b0 \fs15 oven}{\b0 \fs15 (Memert),}{\b0 \fs15 mesin}{\b0 \fs15 tablet}{\b0\
i \fs15 single}{\b0\i \fs15 punch}{\b0 \fs15 (}{\b0\i \fs15 Korch}{\b0 \fs15
type}{\b0 \fs15 EK}{\b0 \fs15 O),}{\b0\i \fs15 Hardness}{\b0\i \fs15 Tester
}{\b0 \fs15 (}{\b0\i \fs15 Vanguard}{\b0 \fs15 type}{\b0 \fs15 YD- }
\par}{\phpg\posx2678\pvpg\posy4311\absw7475\absh2831 \sl-295 \b \f10 \fs16 \cf0
{\b0 \fs15 2),}{\b0\i \fs15 Friability}{\b0\i \fs15 Tester}{\b0 \fs15 (}{\b0\
i \fs15 Erweka}{\b0 \fs15 type}{\b0 \fs15 T-200),}{\b0 \fs15 alat}{\b0 \fs15
penghisap}{\b0 \fs15 debu}{\b0 \fs15 (}{\b0\i \fs15 lux}{\b0 \fs15 ). }\par
}
{\phpg\posx2678\pvpg\posy7850\absw7472\absh3064 \b \f10 \fs15 \cf0 \b \f10 \fs15
\cf0 Preparasi Akar Ginseng Jawa
\par}{\phpg\posx2678\pvpg\posy7850\absw7472\absh3064 \sl-292 \b \f10 \fs15 \cf0
{\b0 Bagian}{\b0 akar}{\b0 ginseng}{\b0 jawa}{\b0 yang}{\b0 telah}{\b0
dikeringkan,}{\b0 dihaluskan}{\b0 dengan}{\b0\i blender}{\b0 kemudian
}{\b0 disari }
\par}{\phpg\posx2678\pvpg\posy7850\absw7472\absh3064 \sl-292 \b \f10 \fs15 \cf0
{\b0 menggunakan}{\b0 cara}{\b0 infundasi.}{\b0 Ekstrak}{\b0 cair}{\b0
yang}{\b0 diperoleh}{\b0 dikeringkan}{\b0 menggunakan}{\b0 alat}{\b0
Spry }
\par}{\phpg\posx2678\pvpg\posy7850\absw7472\absh3064 \sl-290 \b \f10 \fs15 \cf0
{\b0 Drying}{\b0 sehingga}{\b0 dihasilkan}{\b0 serbuk}{\b0 ekstrak}{\b0 ker
ing. }
\par}{\phpg\posx2678\pvpg\posy7850\absw7472\absh3064 \sl-295 \b \f10 \fs15 \cf0
Pembuatan Tablet{\i effervescent} ekstrak ginseng jawa
\par}{\phpg\posx2678\pvpg\posy7850\absw7472\absh3064 \sl-290 \b \f10 \fs15 \cf0
{\b0 Formulasi}{\b0 tablet}{\b0 effervescent}{\b0 ekstrak}{\b0 ginseng}{\b0
jawa}{\b0 dibuat}{\b0 sesuai}{\b0 dengan}{\b0 formula}{\b0 yang}{\b0 ditu
njukkan }
\par}{\phpg\posx2678\pvpg\posy7850\absw7472\absh3064 \sl-292 \b \f10 \fs15 \cf0
{\b0 pada}{\b0 tabel}{\b0 1.}{\b0 Serbuk}{\b0 kering}{\b0 ekstrak}{\b0 gin
seng}{\b0 jawa}{\b0 dicampur}{\b0 dengan}{\b0 manitol}{\b0 kemudian}{\b0 b
erturut-turut }
\par}{\phpg\posx2678\pvpg\posy7850\absw7472\absh3064 \sl-292 \b \f10 \fs15 \cf0
{\b0 ditambahkan}{\b0 asam}{\b0 sitrat,}{\b0 asam}{\b0 tartrat}{\b0 dan}{\b
0 natrium}{\b0 bikarbonat.}{\b0 Campuran}{\b0 diaduk}{\b0 sampai}{\b0 homo
gen }
\par}{\phpg\posx2678\pvpg\posy7850\absw7472\absh3064 \sl-290 \b \f10 \fs15 \cf0
{\b0 kemudian}{\b0 dikeringkan}{\b0 dalam}{\b0 oven}{\b0 pada}{\b0 suh
u}{\b0 70ºC}{\b0 selama}{\b0 45}{\b0 menit.}{\b0 Campuran}{\b0 diayak}
{\b0 dengan }
\par}{\phpg\posx2678\pvpg\posy7850\absw7472\absh3064 \sl-295 \b \f10 \fs15 \cf0
{\b0 ukuran}{\b0 mesh}{\b0 40,}{\b0 selanjutnya}{\b0 di}{\b0 tambahkan
}{\b0 PEG}{\b0 4000}{\b0 dan}{\b0 pemanis}{\b0 aspartam,}{\b0 campur
an}{\b0 diaduk }
\par}{\phpg\posx2678\pvpg\posy7850\absw7472\absh3064 \sl-290 \b \f10 \fs15 \cf0
{\b0 sampai}{\b0 homogen}{\b0 dan}{\b0 dicetak}{\b0 menggunakan}{\b0 mesin}
{\b0 cetak}{\b0 tablet}{\b0\i single}{\b0\i punch}{\b0 (}{\b0\i Korch}{\b0
type}{\b0 EK}{\b0 O). }
\par}{\phpg\posx2678\pvpg\posy7850\absw7472\absh3064 \sl-292 \b \f10 \fs15 \cf0
\fi1334 Tabel 1. Formula Tablet Effervescent Ekstrak Ginseng Jawa \par
}
{\phpg\posx2678\pvpg\posy11664\absw1430\absh2077 \f10 \fs15 \cf0 \fi523 \f10 \fs
15 \cf0 Bahan (mg)
\par}{\phpg\posx2678\pvpg\posy11664\absw1430\absh2077 \sl-153 \par\f10 \fs15 \cf
0 Ekstrak kering
\par}{\phpg\posx2678\pvpg\posy11664\absw1430\absh2077 \sl-302 \f10 \fs15 \cf0 As
am sitrat
\par}{\phpg\posx2678\pvpg\posy11664\absw1430\absh2077 \sl-302 \f10 \fs15 \cf0 As
am tartrat
\par}{\phpg\posx2678\pvpg\posy11664\absw1430\absh2077 \sl-302 \f10 \fs15 \cf0 Na
trium bikarbonat
\par}{\phpg\posx2678\pvpg\posy11664\absw1430\absh2077 \sl-300 \f10 \fs15 \cf0 PE
G 4000
\par}{\phpg\posx2678\pvpg\posy11664\absw1430\absh2077 \sl-302 \f10 \fs15 \cf0 As
partam
\par}{\phpg\posx2678\pvpg\posy11664\absw1430\absh2077 \sl-302 \f10 \fs15 \cf0 Ma
nitol \par
}
{\phpg\posx4814\pvpg\posy11369\absw994\absh2343 \f10 \fs15 \cf0 \f10 \fs15 \cf0
Formula I
\par}{\phpg\posx4814\pvpg\posy11369\absw994\absh2343 \sl-300 \f10 \fs15 \cf0 3%
aspartam
\par}{\phpg\posx4814\pvpg\posy11369\absw994\absh2343 \sl-302 \f10 \fs15 \cf0 150
\par}{\phpg\posx4814\pvpg\posy11369\absw994\absh2343 \sl-302 \f10 \fs15 \cf0 270
\par}{\phpg\posx4814\pvpg\posy11369\absw994\absh2343 \sl-302 \f10 \fs15 \cf0 540
\par}{\phpg\posx4814\pvpg\posy11369\absw994\absh2343 \sl-302 \f10 \fs15 \cf0 850

\par}{\phpg\posx4814\pvpg\posy11369\absw994\absh2343 \sl-300 \f10 \fs15 \cf0 40


\par}{\phpg\posx4814\pvpg\posy11369\absw994\absh2343 \sl-302 \f10 \fs15 \cf0 60
\par}{\phpg\posx4814\pvpg\posy11369\absw994\absh2343 \sl-302 \f10 \fs15 \cf0 90
\par
}
{\phpg\posx6679\pvpg\posy11369\absw1136\absh2343 \f10 \fs15 \cf0 \f10 \fs15 \cf0
Formula II
\par}{\phpg\posx6679\pvpg\posy11369\absw1136\absh2343 \sl-300 \f10 \fs15 \cf0 3,
5% aspartam
\par}{\phpg\posx6679\pvpg\posy11369\absw1136\absh2343 \sl-302 \f10 \fs15 \cf0 15
0
\par}{\phpg\posx6679\pvpg\posy11369\absw1136\absh2343 \sl-302 \f10 \fs15 \cf0 27
0
\par}{\phpg\posx6679\pvpg\posy11369\absw1136\absh2343 \sl-302 \f10 \fs15 \cf0 54
0
\par}{\phpg\posx6679\pvpg\posy11369\absw1136\absh2343 \sl-302 \f10 \fs15 \cf0 85
0
\par}{\phpg\posx6679\pvpg\posy11369\absw1136\absh2343 \sl-300 \f10 \fs15 \cf0 40
\par}{\phpg\posx6679\pvpg\posy11369\absw1136\absh2343 \sl-302 \f10 \fs15 \cf0 70
\par}{\phpg\posx6679\pvpg\posy11369\absw1136\absh2343 \sl-302 \f10 \fs15 \cf0 80
\par
}
{\phpg\posx8543\pvpg\posy11369\absw994\absh2343 \f10 \fs15 \cf0 \f10 \fs15 \cf0
Formula III
\par}{\phpg\posx8543\pvpg\posy11369\absw994\absh2343 \sl-300 \f10 \fs15 \cf0 4%
aspartam
\par}{\phpg\posx8543\pvpg\posy11369\absw994\absh2343 \sl-302 \f10 \fs15 \cf0 150
\par}{\phpg\posx8543\pvpg\posy11369\absw994\absh2343 \sl-302 \f10 \fs15 \cf0 270
\par}{\phpg\posx8543\pvpg\posy11369\absw994\absh2343 \sl-302 \f10 \fs15 \cf0 540
\par}{\phpg\posx8543\pvpg\posy11369\absw994\absh2343 \sl-302 \f10 \fs15 \cf0 850
\par}{\phpg\posx8543\pvpg\posy11369\absw994\absh2343 \sl-300 \f10 \fs15 \cf0 40
\par}{\phpg\posx8543\pvpg\posy11369\absw994\absh2343 \sl-302 \f10 \fs15 \cf0 80
\par}{\phpg\posx8543\pvpg\posy11369\absw994\absh2343 \sl-302 \f10 \fs15 \cf0 70
\par
}
{\phpg\posx9923\pvpg\posy14674\absw281\absh225 \f20 \fs20 \cf0 \f20 \fs20 \cf0 4
4 \par
}
\sect\sectd\pard\plain
\pgwsxn12240\pghsxn15840
{\phpg\posx0\pvpg\posy0\absw12240\absh15840 \overlay
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0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a
0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a
0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a0028a28a
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51451400514514005145140051451400514514005145140051451400514514005145140051451400
51451400514514005145140051451400514514005145140051451400514514005145140051451400
51451400514514005145140051451400514514005145140051451400514514005145140051451400
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51451400514514005145140051451401ffd9
}}\par}{\phpg\posx2678\pvpg\posy2165\absw7472\absh2539 \b \f10 \fs15 \cf0 \b \f1
0 \fs15 \cf0 Uji Kualitas Tablet Effervescent
\par}{\phpg\posx2678\pvpg\posy2165\absw7472\absh2539 \sl-292 \b \f10 \fs15 \cf0
\fi679 Uji sifat fisik granul{\b0 .}{\b0 Sebelum}{\b0 granul}{\b0 dicet
ak,}{\b0 terlebih}{\b0 dahulu}{\b0 dilakukan}{\b0 uji}{\b0 sifat}{\b0
fisik }
\par}{\phpg\posx2678\pvpg\posy2165\absw7472\absh2539 \sl-292 \b \f10 \fs15 \cf0
{\b0 granul}{\b0 yang}{\b0 meliputi}{\b0 kecepatan}{\b0 alir,}{\b0 sudut}{\
b0 diam,}{\b0 pengetapan,}{\b0 dan}{\b0 densitas}{\b0 massa }
\par}{\phpg\posx2678\pvpg\posy2165\absw7472\absh2539 \sl-292 \b \f10 \fs15 \cf0
\fi679 Kecepatan alir.{\b0 Granul}{\b0 seberat}{\b0 100}{\b0 gram}{\b0
dituang}{\b0 perlahan-lahan}{\b0 kedalam}{\b0 corong}{\b0 yang }
\par}{\phpg\posx2678\pvpg\posy2165\absw7472\absh2539 \sl-290 \b \f10 \fs15 \cf0
{\b0 tertutup}{\b0 bagian}{\b0 bawahnya}{\b0 lewat}{\b0 tepi}{\b0 coro
ng.}{\b0 Buka}{\b0 tutup}{\b0 corong}{\b0 secara}{\b0 perlahan-lahan}{
\b0 biarkan }
\par}{\phpg\posx2678\pvpg\posy2165\absw7472\absh2539 \sl-295 \b \f10 \fs15 \cf0
{\b0 granul}{\b0 mengalir}{\b0 keluar.}{\b0 Dicatat}{\b0 waktu}{\b0 ya
ng}{\b0 diperlukan}{\b0 (detik)}{\b0 dengan}{\b0\i stop}{\b0\i watch}{
\b0 sampai}{\b0 semua }
\par}{\phpg\posx2678\pvpg\posy2165\absw7472\absh2539 \sl-290 \b \f10 \fs15 \cf0
{\b0 granul}{\b0 melewati}{\b0 corong}{\b0 (Parrott,}{\b0 1971).}{\b0
Kecepatan}{\b0 alir}{\b0 granul}{\b0 yang}{\b0 baik}{\b0 adalah}{\b0
lebih}{\b0 dari}{\b0 10 }
\par}{\phpg\posx2678\pvpg\posy2165\absw7472\absh2539 \sl-292 \b \f10 \fs15 \cf0
{\b0 gram/detik}{\b0 (Carstensen}{\b0 dan}{\b0 Chan,}{\b0 1977). }
\par}{\phpg\posx2678\pvpg\posy2165\absw7472\absh2539 \sl-292 \b \f10 \fs15 \cf0
\fi679 Sudut diam.{\b0 Granul}{\b0 seberat}{\b0 100}{\b0 gram}{\b0 di
tuang}{\b0 secara}{\b0 perlahan}{\b0 melalui}{\b0 dinding}{\b0 corong.
}
\par}{\phpg\posx2678\pvpg\posy2165\absw7472\absh2539 \sl-292 \b \f10 \fs15 \cf0
{\b0 Buka}{\b0 penutup}{\b0 corong}{\b0 dan}{\b0 biarkan}{\b0 granul}{
\b0 mengalir.}{\b0 Ukur}{\b0 tinggi}{\b0 kerucut}{\b0 dan}{\b0 jari-
jari}{\b0 kerucut}{\b0 yang }\par
}
{\phpg\posx2678\pvpg\posy5270\absw4980\absh170 \f10 \fs15 \cf0 \f10 \fs15 \cf0 t
erbentuk. Sudut diam dihitung berdasarkan rumus berikut : Tg{\f20 {\field{\*\fl
dinst SYMBOL 97 \\f Symbol }}}= \par
}
{\phpg\posx7718\pvpg\posy5083\absw146\absh508 \i \f20 \fs20 \cf0 \i \f20 \fs20 \
cf0 h
\par}{\phpg\posx7718\pvpg\posy5083\absw146\absh508 \sl-314 \i \f20 \fs20 \cf0 r
\par
}
{\phpg\posx2678\pvpg\posy5731\absw7469\absh1224 \b \f10 \fs15 \cf0 \fi679 \b \f1
0 \fs15 \cf0 Pengetapan.{\b0 Granul}{\b0 dituang}{\b0 pelan-pelan}{\b0 kedal
am}{\b0 gelas}{\b0 ukur}{\b0 sampai}{\b0 volume}{\b0 100}{\b0 ml}{\b0 dan
}
\par}{\phpg\posx2678\pvpg\posy5731\absw7469\absh1224 \sl-295 \b \f10 \fs15 \cf0
{\b0 dicatat}{\b0 sebagai}{\b0 Vo.}{\b0 Gelas}{\b0 ukur}{\b0 dipasang}{\b0
pada}{\b0 alat}{\b0 dan}{\b0 motor}{\b0 dihidupkan.}{\b0 Catat}{\b0 perub
ahan}{\b0 volume }
\par}{\phpg\posx2678\pvpg\posy5731\absw7469\absh1224 \sl-290 \b \f10 \fs15 \cf0
{\b0 pada}{\b0 tap}{\b0 ke}{\b0 5,}{\b0 10,}{\b0 15}{\b0 dan}{\b0
seterusnya}{\b0 sampai}{\b0 volume}{\b0 granul}{\b0 konstan}{\b0 dan}{
\b0 dicatat}{\b0 sebagai}{\b0 Vt. }
\par}{\phpg\posx2678\pvpg\posy5731\absw7469\absh1224 \sl-292 \b \f10 \fs15 \cf0
{\b0 Kemudian}{\b0 bobot}{\b0 granul}{\b0 ditimbang.}{\b0 Pengurangan}{\
b0 volume}{\b0 granul}{\b0 akibat}{\b0 pengetapan}{\b0 dinyatakan }
\par}{\phpg\posx2678\pvpg\posy5731\absw7469\absh1224 \sl-292 \b \f10 \fs15 \cf0
{\b0 sebagai}{\b0 harga}{\b0 Tap}{\b0 (%)}{\b0 (Fassihi}{\b0 &}{\b0 Kanfer
,}{\b0 1986). }\par
}
{\phpg\posx2726\pvpg\posy7375\absw423\absh170 \f10 \fs15 \cf0 \f10 \fs15 \cf0 %T
= \par
}
{\phpg\posx3165\pvpg\posy7162\absw652\absh531 \i \f20 \fs20 \cf0 \i \f20 \fs20 \
cf0 Vo{\i0 \f40 {\f63 \u61485\'3f}}Vt
\par}{\phpg\posx3165\pvpg\posy7162\absw652\absh531 \sl-314 \i \f20 \fs20 \cf0 \f
i199 Vo \par
}
{\phpg\posx3873\pvpg\posy7329\absw736\absh225 \i \f20 \fs20 \cf0 \i \f20 \fs20 \
cf0 x{\i0 100% }\par
}
{\phpg\posx2678\pvpg\posy7838\absw7470\absh697 \b \f10 \fs15 \cf0 \fi679 \b \f10
\fs15 \cf0 Densitas massa.{\b0 Gelas}{\b0 ukur}{\b0 100}{\b0 ml}{\b0
ditimbang,}{\b0 granul}{\b0 dimasukkan}{\b0 kedalam}{\b0 gelas}{\b0 u
kur }
\par}{\phpg\posx2678\pvpg\posy7838\absw7470\absh697 \sl-292 \b \f10 \fs15 \cf0 {
\b0 hingga}{\b0 volumenya}{\b0 mencapai}{\b0 100}{\b0 ml}{\b0 lewat}{\
b0 tepi}{\b0 gelas}{\b0 ukur.}{\b0 Gelas}{\b0 ukur}{\b0 yang}{\b0
sudah}{\b0 diisi}{\b0 granul }
\par}{\phpg\posx2678\pvpg\posy7838\absw7470\absh697 \sl-292 \b \f10 \fs15 \cf0 {
\b0 tersebut}{\b0 kemudian}{\b0 ditimbang.}{\b0 Densitas}{\b0 granul}{\b0 t
ersebut}{\b0 dihitung}{\b0 dengan}{\b0 rumus}{\b0 berikut. }\par
}
{\phpg\posx2678\pvpg\posy8899\absw266\absh170 \f10 \fs15 \cf0 \f10 \fs15 \cf0 P
= \par
}
{\phpg\posx3035\pvpg\posy8684\absw5350\absh533 \f20 \fs20 \cf0 \f20 \fs20 \cf0 (
{\i bobot}{\i gelas}{\i ukur}{\f40 {\f63 \u61483\'3f}}{\i granul}){\f40 {
\f63 \u61485\'3f}}{\i bobot}{\i gelas}{\i ukur}{\i kosong }
\par}{\phpg\posx3035\pvpg\posy8684\absw5350\absh533 \sl-316 \f20 \fs20 \cf0 \fi1
732 {\i volume}{\i gelas}{\i ukur }\par
}
{\phpg\posx2678\pvpg\posy9689\absw7472\absh960 \b \f10 \fs15 \cf0 \b \f10 \fs15
\cf0 Uji Sifat Fisik Tablet.
\par}{\phpg\posx2678\pvpg\posy9689\absw7472\absh960 \sl-292 \b \f10 \fs15 \cf0 {
\b0 Untuk}{\b0 mengetahui}{\b0 kualitas}{\b0 tablet}{\b0 yang}{\b0 telah}{\
b0 dicetak,}{\b0 maka}{\b0 dilakukan}{\b0 uji}{\b0 sifat}{\b0 fisik}{\b0
tablet}{\b0 yang }
\par}{\phpg\posx2678\pvpg\posy9689\absw7472\absh960 \sl-292 \b \f10 \fs15 \cf0 {
\b0 meliputi,}{\b0 keseragaman}{\b0 bobot,}{\b0 kekerasan,}{\b0 kerapuhan,}{
\b0 dan}{\b0 waktu}{\b0 larut. }
\par}{\phpg\posx2678\pvpg\posy9689\absw7472\absh960 \sl-292 \b \f10 \fs15 \cf0 \
fi679 Keseragaman bobot{\b0 .}{\b0 Dua}{\b0 puluh}{\b0 tablet}{\b0\i
effervescent}{\b0 ditimbang}{\b0 satu}{\b0 persatu}{\b0 dengan }\par
}
{\phpg\posx7046\pvpg\posy10861\absw37\absh87 \f20 \fs6 \cf0 \f20 \fs6 \cf0 _ \pa
r
}
{\phpg\posx2678\pvpg\posy10882\absw7472\absh2803 \f10 \fs15 \cf0 \f10 \fs15 \cf0
neraca elektrik. Kemudian dihitung harga rata-rata ({\i \f20 \fs11
x} ), Standar Deviasi (SD) dan persen
\par}{\phpg\posx2678\pvpg\posy10882\absw7472\absh2803 \sl-295 \f10 \fs15 \cf0 pe
nyimpangan bobot. Hasil yang diperoleh dibandingkan dengan persyaratan y
ang ada dalam
\par}{\phpg\posx2678\pvpg\posy10882\absw7472\absh2803 \sl-290 \f10 \fs15 \cf0 Fa
rmakope Indonesia (Anonim, 1979).
\par}{\phpg\posx2678\pvpg\posy10882\absw7472\absh2803 \sl-295 \f10 \fs15 \cf0 \f
i679 {\b Kekerasan.} Sebuah tablet diletakkan pada alat{\i hardness}{\i
tester} ({\i Vanguard} type YD-2)
\par}{\phpg\posx2678\pvpg\posy10882\absw7472\absh2803 \sl-290 \f10 \fs15 \cf0 Al
at ini secara otomatis akan menentukan kekerasan tablet yang kemudian
hasilnya dapat dilihat
\par}{\phpg\posx2678\pvpg\posy10882\absw7472\absh2803 \sl-292 \f10 \fs15 \cf0 da
ri angka yang muncul pada alat tersebut. Dilakukan terhadap 10 tablet.
\par}{\phpg\posx2678\pvpg\posy10882\absw7472\absh2803 \sl-292 \f10 \fs15 \cf0 \f
i679 {\b Kerapuhan.} Dua puluh tablet dibebas debukan dengan aspirator kemudian
ditimbang lalu
\par}{\phpg\posx2678\pvpg\posy10882\absw7472\absh2803 \sl-292 \f10 \fs15 \cf0 di
masukkan ke{\i friability}{\i tester} ({\i Erweka} type T-200) Alat dihidupkan
dan diputar dengan kecepatan
\par}{\phpg\posx2678\pvpg\posy10882\absw7472\absh2803 \sl-290 \f10 \fs15 \cf0 25
rpm selama 4 menit. Setelah selesai tablet dikeluarkan dari alat dibebasdebukan
dan ditimbang
\par}{\phpg\posx2678\pvpg\posy10882\absw7472\absh2803 \sl-295 \f10 \fs15 \cf0 la
gi. Dihitung persentase bobot tablet yang berkurang dari bobot tablet mula-mula.
\par}{\phpg\posx2678\pvpg\posy10882\absw7472\absh2803 \sl-290 \f10 \fs15 \cf0 \f
i679 {\b Waktu}{\b larut.} Sebuah tablet dimasukkan ke dalam air dengan
volume 200 ml pada suhu \par
}
{\phpg\posx9923\pvpg\posy14674\absw281\absh225 \f20 \fs20 \cf0 \f20 \fs20 \cf0 4
5 \par
}
\sect\sectd\pard\plain
\pgwsxn12240\pghsxn15840
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\par}{\phpg\posx2678\pvpg\posy4311\absw7474\absh4410 \sl-292 \b \f10 \fs16 \cf0
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\par}{\phpg\posx2678\pvpg\posy4311\absw7474\absh4410 \sl-290 \b \f10 \fs16 \cf0
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\par}{\phpg\posx2678\pvpg\posy4311\absw7474\absh4410 \sl-295 \b \f10 \fs16 \cf0
{\b0 \fs15 yang}{\b0 \fs15 paling}{\b0 \fs15 besar}{\b0 \fs15 dibanding}{\b0
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}
{\phpg\posx3300\pvpg\posy9605\absw6281\absh170 \b \f10 \fs15 \cf0 \b \f10 \fs15
\cf0 Tabel 2. Hasil Uji sifat Fisik Granul Tablet Effervescent Ekstrak Ginseng J
awa \par
}
{\phpg\posx2678\pvpg\posy9907\absw1687\absh1081 \b \f10 \fs15 \cf0 \fi554 \b \f1
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{\b0 Sudut}{\b0 diam}{\b0 (º) }
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{\b0 Pengetapan}{\b0 (%) }
\par}{\phpg\posx2678\pvpg\posy9907\absw1687\absh1081 \sl-204 \b \f10 \fs15 \cf0
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}
{\phpg\posx4790\pvpg\posy9907\absw1376\absh1081 \b \f10 \fs15 \cf0 \fi381 \b \f1
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\par}{\phpg\posx4790\pvpg\posy9907\absw1376\absh1081 \sl-194 \b \f10 \fs15 \cf0
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\par}{\phpg\posx4790\pvpg\posy9907\absw1376\absh1081 \sl-204 \b \f10 \fs15 \cf0
{\b0 19,2}{\b0 ±}{\b0 1,4 }
\par}{\phpg\posx4790\pvpg\posy9907\absw1376\absh1081 \sl-204 \b \f10 \fs15 \cf0
{\b0 29,9}{\b0 ±}{\b0 0,6 }
\par}{\phpg\posx4790\pvpg\posy9907\absw1376\absh1081 \sl-206 \b \f10 \fs15 \cf0
{\b0 11,3}{\b0 ±}{\b0 0,3 }
\par}{\phpg\posx4790\pvpg\posy9907\absw1376\absh1081 \sl-204 \b \f10 \fs15 \cf0
{\b0 0,63}{\b0 ±}{\b0 0,05 }\par
}
{\phpg\posx6520\pvpg\posy9907\absw1530\absh1081 \b \f10 \fs15 \cf0 \fi453 \b \f1
0 \fs15 \cf0 Formula II
\par}{\phpg\posx6520\pvpg\posy9907\absw1530\absh1081 \sl-194 \b \f10 \fs15 \cf0
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\par}{\phpg\posx6520\pvpg\posy9907\absw1530\absh1081 \sl-204 \b \f10 \fs15 \cf0
{\b0 18,4}{\b0 ±}{\b0 0,9 }
\par}{\phpg\posx6520\pvpg\posy9907\absw1530\absh1081 \sl-204 \b \f10 \fs15 \cf0
{\b0 30,4}{\b0 ±}{\b0 2,4 }
\par}{\phpg\posx6520\pvpg\posy9907\absw1530\absh1081 \sl-206 \b \f10 \fs15 \cf0
{\b0 12,5}{\b0 ±}{\b0 0,5 }
\par}{\phpg\posx6520\pvpg\posy9907\absw1530\absh1081 \sl-204 \b \f10 \fs15 \cf0
{\b0 0,51}{\b0 ±}{\b0 0,02 }\par
}
{\phpg\posx8438\pvpg\posy9907\absw1467\absh1081 \b \f10 \fs15 \cf0 \fi427 \b \f1
0 \fs15 \cf0 Formula III
\par}{\phpg\posx8438\pvpg\posy9907\absw1467\absh1081 \sl-194 \b \f10 \fs15 \cf0
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{\b0 17,9}{\b0 ±}{\b0 0,6 }
\par}{\phpg\posx8438\pvpg\posy9907\absw1467\absh1081 \sl-204 \b \f10 \fs15 \cf0
{\b0 32,3}{\b0 ±}{\b0 0,3 }
\par}{\phpg\posx8438\pvpg\posy9907\absw1467\absh1081 \sl-206 \b \f10 \fs15 \cf0
{\b0 14,8}{\b0 ±}{\b0 0,8 }
\par}{\phpg\posx8438\pvpg\posy9907\absw1467\absh1081 \sl-204 \b \f10 \fs15 \cf0
{\b0 0,51}{\b0 ±}{\b0 0,00 }\par
}
{\phpg\posx2678\pvpg\posy11417\absw7474\absh2537 \b \f10 \fs15 \cf0 \fi679 \b \f
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{\b0 karena}{\b0 sifat}{\b0 dari}{\b0 tablet}{\b0\i effervescent}{\b0
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{\b0 dapat}{\b0 berpengaruh}{\b0 pada}{\b0 hasil}{\b0 uji. }
\par}{\phpg\posx2678\pvpg\posy11417\absw7474\absh2537 \sl-292 \b \f10 \fs15 \cf0
{\b0 Kekerasan}{\b0 tablet}{\b0 effervescent}{\b0 ekstrak}{\b0 gins
eng}{\b0 jawa}{\b0 diperoleh}{\b0 bahwa}{\b0 hasil}{\b0 uji}{\b0
memenuhi }
\par}{\phpg\posx2678\pvpg\posy11417\absw7474\absh2537 \sl-292 \b \f10 \fs15 \cf0
{\b0 persyaratan}{\b0 mutu}{\b0 kekerasan}{\b0 tablet}{\b0 yang}{\b0
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}{\b0 (Banker}{\b0 dan }
\par}{\phpg\posx2678\pvpg\posy11417\absw7474\absh2537 \sl-290 \b \f10 \fs15 \cf0
{\b0 Anderson}{\b0\i ,}{\b0 1986)}{\b0 (tabel}{\b0 3).}{\b0 Antara}
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\par}{\phpg\posx2678\pvpg\posy11417\absw7474\absh2537 \sl-292 \b \f10 \fs15 \cf0
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u}{\b0 arah }
\par}{\phpg\posx2678\pvpg\posy11417\absw7474\absh2537 \sl-292 \b \f10 \fs15 \cf0
{\b0 (ANOVA)}{\b0 (p<0,05). }
\par}{\phpg\posx2678\pvpg\posy11417\absw7474\absh2537 \sl-292 \b \f10 \fs15 \cf0
\fi679 {\b0 Kerapuhan}{\b0 tablet}{\b0 juga}{\b0 tidak}{\b0 menunjukkan}{\b
0 perbedaan}{\b0 yang}{\b0 bermakna}{\b0 pada}{\b0 tiap}{\b0 formulasi }\p
ar
}
{\phpg\posx9923\pvpg\posy14674\absw281\absh225 \f20 \fs20 \cf0 \f20 \fs20 \cf0 4
6 \par
}
\sect\sectd\pard\plain
\pgwsxn12240\pghsxn15840
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2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a
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2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a
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2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a
2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a
2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a
2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a
2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a
2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a
2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a
2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a
2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a
2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a
2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2800a28a2803ffd9
}}\par}{\phpg\posx2678\pvpg\posy2165\absw7472\absh4200 \f10 \fs15 \cf0 \f10 \fs1
5 \cf0 tablet effervescent yang dibuat, namun prosentase kerapuhan
yang dihasilkan tiap formula
\par}{\phpg\posx2678\pvpg\posy2165\absw7472\absh4200 \sl-292 \f10 \fs15 \cf0 mem
enuhi syarat mutu tablet yang baik yaitu di bawah 1% (Banker
dan Anderson, 1986).
\par}{\phpg\posx2678\pvpg\posy2165\absw7472\absh4200 \sl-292 \f10 \fs15 \cf0 Ker
apuhan yang paling kecil diperoleh dari formula III (tabel 3). Kerapuhan meru
pakan gambaran
\par}{\phpg\posx2678\pvpg\posy2165\absw7472\absh4200 \sl-292 \f10 \fs15 \cf0 dar
i kekuatan ikatan partikel dari bahan-bahan pembentuk tablet, semakin k
ompak ikatan antar
\par}{\phpg\posx2678\pvpg\posy2165\absw7472\absh4200 \sl-290 \f10 \fs15 \cf0 pen
yusun tablet tersebut maka tablet akan semakin tahan terhadap proses p
engikisan. Terdapat
\par}{\phpg\posx2678\pvpg\posy2165\absw7472\absh4200 \sl-295 \f10 \fs15 \cf0 hub
ungan antara kekerasan tablet dan kerapuhan, yaitu semakin tinggi keker
asan tablet maka
\par}{\phpg\posx2678\pvpg\posy2165\absw7472\absh4200 \sl-290 \f10 \fs15 \cf0 ika
tan antar partikel penyusun tablet semakin kuat sehingga kerapuhannya a
kan semakin kecil.
\par}{\phpg\posx2678\pvpg\posy2165\absw7472\absh4200 \sl-292 \f10 \fs15 \cf0 Beg
itu pula sebaliknya.
\par}{\phpg\posx2678\pvpg\posy2165\absw7472\absh4200 \sl-292 \f10 \fs15 \cf0 \fi
679 Hasil uji waktu larut tablet dari semua formula menunjukkan
bahwa waktu yang
\par}{\phpg\posx2678\pvpg\posy2165\absw7472\absh4200 \sl-292 \f10 \fs15 \cf0 dib
utuhkan untuk melarut tidak memenuhi pesyaratan mutu tablet yang baik.
Tablet effervescent
\par}{\phpg\posx2678\pvpg\posy2165\absw7472\absh4200 \sl-292 \f10 \fs15 \cf0 yan
g baik akan larut dalam waktu 1-2 menit, sedangkan waktu larut tablet
effervescent tablet
\par}{\phpg\posx2678\pvpg\posy2165\absw7472\absh4200 \sl-290 \f10 \fs15 \cf0 eks
trak ginseng jawa adalah 7-8 menit (tabel 3). Factor yang sangat berpengaruh ter
hadap waktu
\par}{\phpg\posx2678\pvpg\posy2165\absw7472\absh4200 \sl-292 \f10 \fs15 \cf0 lar
ut tablet effervescent adalah bahan penghancur berupa sumber asam (asam
tartrat dan asam
\par}{\phpg\posx2678\pvpg\posy2165\absw7472\absh4200 \sl-292 \f10 \fs15 \cf0 sit
rat) dan sumber basa (Natrium bikarbonat). Oleh karena itu dalam prose
s pencampuran kedua
\par}{\phpg\posx2678\pvpg\posy2165\absw7472\absh4200 \sl-292 \f10 \fs15 \cf0 bah
an ini dilakukan dengan hati-hati sehingga tidak terjadi reaksi
dini yang mengakibatkan
\par}{\phpg\posx2678\pvpg\posy2165\absw7472\absh4200 \sl-189 \par\f10 \fs15 \cf0
terlepasnya CO{\dn006 \f20 \fs11 2}. \par
}
{\phpg\posx3587\pvpg\posy7205\absw5702\absh170 \b \f10 \fs15 \cf0 \b \f10 \fs15
\cf0 Tabel 3. Hasil Uji Sifat Fisik Tablet Effervescent Ekstrak Ginseng Jawa \pa
r
}
{\phpg\posx3227\pvpg\posy7507\absw799\absh170 \b \f10 \fs15 \cf0 \b \f10 \fs15 \
cf0 Sifat Fisik \par
}
{\phpg\posx2678\pvpg\posy8100\absw1430\absh714 \f10 \fs15 \cf0 \f10 \fs15 \cf0 K
ekerasan (kg)
\par}{\phpg\posx2678\pvpg\posy8100\absw1430\absh714 \sl-302 \f10 \fs15 \cf0 Kera
puhan (%)
\par}{\phpg\posx2678\pvpg\posy8100\absw1430\absh714 \sl-302 \f10 \fs15 \cf0 Wakt
u larut (menit) \par
}
{\phpg\posx4783\pvpg\posy7507\absw1378\absh1248 \b \f10 \fs15 \cf0 \fi381 \b \f1
0 \fs15 \cf0 Formula I
\par}{\phpg\posx4783\pvpg\posy7507\absw1378\absh1248 \sl-290 \b \f10 \fs15 \cf0
\fi172 (Aspartam 3%)
\par}{\phpg\posx4783\pvpg\posy7507\absw1378\absh1248 \sl-302 \b \f10 \fs15 \cf0
{\b0 9,03}{\b0 ±}{\b0 0,99 }
\par}{\phpg\posx4783\pvpg\posy7507\absw1378\absh1248 \sl-302 \b \f10 \fs15 \cf0
{\b0 0,56}{\b0 ±}{\b0 0,17 }
\par}{\phpg\posx4783\pvpg\posy7507\absw1378\absh1248 \sl-302 \b \f10 \fs15 \cf0
{\b0 7,64}{\b0 ±}{\b0 0,20 }\par
}
{\phpg\posx6515\pvpg\posy7507\absw1532\absh1248 \b \f10 \fs15 \cf0 \fi453 \b \f1
0 \fs15 \cf0 Formula II
\par}{\phpg\posx6515\pvpg\posy7507\absw1532\absh1248 \sl-290 \b \f10 \fs15 \cf0
\fi192 (Aspartam 3,5%)
\par}{\phpg\posx6515\pvpg\posy7507\absw1532\absh1248 \sl-302 \b \f10 \fs15 \cf0
{\b0 9,39}{\b0 ±}{\b0 0,85 }
\par}{\phpg\posx6515\pvpg\posy7507\absw1532\absh1248 \sl-302 \b \f10 \fs15 \cf0
{\b0 0,47}{\b0 ±}{\b0 0,09 }
\par}{\phpg\posx6515\pvpg\posy7507\absw1532\absh1248 \sl-302 \b \f10 \fs15 \cf0
{\b0 8,09}{\b0 ±}{\b0 0,03 }\par
}
{\phpg\posx8435\pvpg\posy7507\absw1470\absh1248 \b \f10 \fs15 \cf0 \fi429 \b \f1
0 \fs15 \cf0 Formula III
\par}{\phpg\posx8435\pvpg\posy7507\absw1470\absh1248 \sl-290 \b \f10 \fs15 \cf0
\fi264 (Aspartam 4%)
\par}{\phpg\posx8435\pvpg\posy7507\absw1470\absh1248 \sl-302 \b \f10 \fs15 \cf0
{\b0 9,64}{\b0 ±}{\b0 0,76 }
\par}{\phpg\posx8435\pvpg\posy7507\absw1470\absh1248 \sl-302 \b \f10 \fs15 \cf0
{\b0 0,41}{\b0 ±}{\b0 0,21 }
\par}{\phpg\posx8435\pvpg\posy7507\absw1470\absh1248 \sl-302 \b \f10 \fs15 \cf0
{\b0 8,42}{\b0 ±}{\b0 0,03 }\par
}
{\phpg\posx2678\pvpg\posy9298\absw7469\absh960 \f10 \fs15 \cf0 \fi679 \f10 \fs15
\cf0 Tanggapan responden terhadap tablet effervescent ekstrak ginseng ja
wa menunjukkan
\par}{\phpg\posx2678\pvpg\posy9298\absw7469\absh960 \sl-292 \f10 \fs15 \cf0 70%
dari seluruh responden menerima rasa tablet dan tidak ada perbedaan bermakna tan
ggapan
\par}{\phpg\posx2678\pvpg\posy9298\absw7469\absh960 \sl-292 \f10 \fs15 \cf0 resp
onden terhadap ketiga formula tersebut, namun beberapa saran dan komentar dari r
esponden
\par}{\phpg\posx2678\pvpg\posy9298\absw7469\absh960 \sl-292 \f10 \fs15 \cf0 agar
tampilan dan warna tablet dibuat lebih menarik. \par
}
{\phpg\posx2678\pvpg\posy10858\absw7469\absh2304 \b \f10 \fs16 \cf0 \b \f10 \fs1
6 \cf0 KESIMPULAN
\par}{\phpg\posx2678\pvpg\posy10858\absw7469\absh2304 \sl-154 \par\b \f10 \fs16
\cf0 \fi340 {\b0 \fs15 1.}{\b0 \fs15 Penambahan}{\b0 \fs15 pemanis}{\b0
\fs15 aspartam}{\b0 \fs15 terhadap}{\b0 \fs15 tablet}{\b0 \fs15 effe
rvescent}{\b0 \fs15 ekstrak}{\b0 \fs15 ginseng}{\b0 \fs15 jawa }
\par}{\phpg\posx2678\pvpg\posy10858\absw7469\absh2304 \sl-290 \b \f10 \fs16 \cf0
\fi679 {\b0 \fs15 menghasilkan}{\b0 \fs15 keseragaman,}{\b0 \fs15 kekerasa
n}{\b0 \fs15 dan}{\b0 \fs15 kerapuhan}{\b0 \fs15 tablet}{\b0 \fs15 memen
uhi}{\b0 \fs15 persyaratan }
\par}{\phpg\posx2678\pvpg\posy10858\absw7469\absh2304 \sl-292 \b \f10 \fs16 \cf0
\fi679 {\b0 \fs15 kualitas}{\b0 \fs15 fisik}{\b0 \fs15 tablet}{\b0 \fs15
yang}{\b0 \fs15 baik,}{\b0 \fs15 sedangkan}{\b0 \fs15 waktu}{\b0 \fs15 l
arutnya}{\b0 \fs15 tidak}{\b0 \fs15 memenuhi}{\b0 \fs15 persyaratan }
\par}{\phpg\posx2678\pvpg\posy10858\absw7469\absh2304 \sl-292 \b \f10 \fs16 \cf0
\fi679 {\b0 \fs15 kualitas}{\b0 \fs15 fisik}{\b0 \fs15 tablet}{\b0 \fs15 yan
g}{\b0 \fs15 baik. }
\par}{\phpg\posx2678\pvpg\posy10858\absw7469\absh2304 \sl-292 \b \f10 \fs16 \cf0
\fi340 {\b0 \fs15 2.}{\b0 \fs15 Variasi}{\b0 \fs15 pemanis}{\b0 \fs15
aspartam}{\b0 \fs15 3%,}{\b0 \fs15 3,5%}{\b0 \fs15 dan}{\b0 \fs15 4%}{\b
0 \fs15 tidak}{\b0 \fs15 menghasilkan}{\b0 \fs15 perubahan}{\b0 \fs15 si
fat}{\b0 \fs15 fisik }
\par}{\phpg\posx2678\pvpg\posy10858\absw7469\absh2304 \sl-290 \b \f10 \fs16 \cf0
\fi679 {\b0 \fs15 tablet}{\b0 \fs15 effervescent}{\b0 \fs15 ekstrak}{\b0 \fs1
5 ginseng}{\b0 \fs15 jawa. }
\par}{\phpg\posx2678\pvpg\posy10858\absw7469\absh2304 \sl-292 \b \f10 \fs16 \cf0
\fi340 {\b0 \fs15 3.}{\b0 \fs15 Sebanyak}{\b0 \fs15 70%}{\b0 \fs15 r
esponden}{\b0 \fs15 menanggapi}{\b0 \fs15 dengan}{\b0 \fs15 puas}{\b0
\fs15 rasa}{\b0 \fs15 ketiga}{\b0 \fs15 formula}{\b0 \fs15 tablet }
\par}{\phpg\posx2678\pvpg\posy10858\absw7469\absh2304 \sl-292 \b \f10 \fs16 \cf0
\fi679 {\b0 \fs15 effervescent}{\b0 \fs15 ekstrak}{\b0 \fs15 ginseng}{\b0 \fs
15 jawa. }\par
}
{\phpg\posx9923\pvpg\posy14674\absw281\absh225 \f20 \fs20 \cf0 \f20 \fs20 \cf0 4
7 \par
}
\sect\sectd\pard\plain
\pgwsxn12240\pghsxn15840
{\phpg\posx0\pvpg\posy0\absw12240\absh15840 \overlay
{\*\shppict {\pict\jpegblip\picw612 \pich792
\picwgoal12240 \pichgoal15840
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}}\par}{\phpg\posx2678\pvpg\posy2165\absw7466\absh727 \b \f10 \fs16 \cf0 \b \f10
\fs16 \cf0 DAFTAR PUSTAKA
\par}{\phpg\posx2678\pvpg\posy2165\absw7466\absh727 \sl-154 \par\b \f10 \fs16 \c
f0 {\b0 \fs15 Anonim,}{\b0 \fs15 1979,}{\b0\i \fs15 Farmakope}{\b0\i \fs15
Indonesia}{\b0 \fs15 ,}{\b0 \fs15 Edisi}{\b0 \fs15 III,}{\b0 \fs15
Departemen}{\b0 \fs15 Kesehatan}{\b0 \fs15 Republik}{\b0 \fs15 Indonesi
a, }
\par}{\phpg\posx2678\pvpg\posy2165\absw7466\absh727 \sl-292 \b \f10 \fs16 \cf0 \
fi933 {\b0 \fs15 Jakarta:}{\b0 \fs15 Halaman}{\b0 \fs15 xxx,}{\b0 \fs15 6,}{\
b0 \fs15 7,}{\b0 \fs15 9. }\par
}
{\phpg\posx2678\pvpg\posy3367\absw7473\absh695 \f10 \fs15 \cf0 \f10 \fs15 \cf0 B
anker, G. S. Dan Anderson, N. R., 1986, Tablet, Dalam Lachman, L., Lieberman, H.
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33 L. (Eds),{\i Teori}{\i dan}{\i Praktek}{\i Farmasi}{\i Industri},
Diterjemahkan oleh Siti Suyatmi, UI
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33 Press, Jakarta: Halaman 645-646, 651, 653, 655, 674-679, 697-699, 701-703. \p
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arstensen, J. T., Chan. P.C., 1977, Flow Rates and Repose An
gles of Wet- Processed
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33 Granulation{\i ,}{\i J.}{\i Pharm.}{\i Sci}, 66(9), p. 1235-1238 \par
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{\phpg\posx2678\pvpg\posy5414\absw7471\absh697 \f10 \fs15 \cf0 \f10 \fs15 \cf0 F
assihi, A.R., Kanfer, I., 1986{\i ,} Effect of Compressibility and Powd
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33 Weight Variation :{\i Drug}{\i Development}{\i and}{\i Industrial}{\i Ph
armacy}, Twelfth Edition, Marcel
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33 Dekker, New York: Halaman 321-358, 1947-1966. \par
}
{\phpg\posx2678\pvpg\posy6583\absw7468\absh433 \f10 \fs15 \cf0 \f10 \fs15 \cf0 H
idayat, Syamsul, 2005,{\i Ginseng}{\i Multivitamin}{\i Alami}{\i
Berkhasiat}, Penebar Swadaya, Jakarta:
\par}{\phpg\posx2678\pvpg\posy6583\absw7468\absh433 \sl-292 \f10 \fs15 \cf0 \fi9
33 Halaman 3, 6-8, 13-15. \par
}
{\phpg\posx2678\pvpg\posy7462\absw7475\absh697 \f10 \fs15 \cf0 \f10 \fs15 \cf0 L
achman L., Lieberman, H. A., dan Kanig, J. L., 1986,{\i Teori}{\i
dan}{\i Praktek}{\i Farmasi}{\i Industri},
\par}{\phpg\posx2678\pvpg\posy7462\absw7475\absh697 \sl-290 \f10 \fs15 \cf0 \fi9
33 Diterjemahkan oleh Siti Suyatmi, UI Press, Jakarta: Halaman 645-646, 6
74-679, 697-
\par}{\phpg\posx2678\pvpg\posy7462\absw7475\absh697 \sl-295 \f10 \fs15 \cf0 \fi9
33 699, 701-703. \par
}
{\phpg\posx2678\pvpg\posy8630\absw708\absh170 \f10 \fs15 \cf0 \f10 \fs15 \cf0 Nu
groho, \par
}
{\phpg\posx3814\pvpg\posy8630\absw193\absh170 \f10 \fs15 \cf0 \f10 \fs15 \cf0 Y.
\par
}
{\phpg\posx4416\pvpg\posy8630\absw239\absh170 \f10 \fs15 \cf0 \f10 \fs15 \cf0 A.
, \par
}
{\phpg\posx5064\pvpg\posy8630\absw447\absh170 \f10 \fs15 \cf0 \f10 \fs15 \cf0 20
01, \par
}
{\phpg\posx5927\pvpg\posy8630\absw584\absh170 \f10 \fs15 \cf0 \f10 \fs15 \cf0 Kh
asiat \par
}
{\phpg\posx6934\pvpg\posy8630\absw308\absh170 \f10 \fs15 \cf0 \f10 \fs15 \cf0 da
n \par
}
{\phpg\posx7654\pvpg\posy8630\absw821\absh170 \f10 \fs15 \cf0 \f10 \fs15 \cf0 Ke
amanan \par
}
{\phpg\posx8913\pvpg\posy8630\absw359\absh170 \f10 \fs15 \cf0 \f10 \fs15 \cf0 So
m \par
}
{\phpg\posx9707\pvpg\posy8630\absw497\absh170 \f10 \fs15 \cf0 \f10 \fs15 \cf0 Ja
wa, \par
}
{\phpg\posx3611\pvpg\posy8923\absw6363\absh433 \f10 \fs15 \cf5 \f10 \fs15 \cf5 h
ttp://www.digilib.litbang.depkes.go.id/go.php?node=132-jkpkbppk-gdl-res-2001-yun
-
\par}{\phpg\posx3611\pvpg\posy8923\absw6363\absh433 \sl-292 \f10 \fs15 \cf5 198-
kolesom{\cf0 (diakses}{\cf0 28}{\cf0 November}{\cf0 2006). }\par
}
{\phpg\posx2678\pvpg\posy9799\absw7473\absh433 \f10 \fs15 \cf0 \f10 \fs15 \cf0 O
livia, F., Alam, S., dan Hadibroto, I., 2006,{\i Seluk-Beluk}{\i Food}{\i S
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33 Utama, Jakarta, 152-153. \par
}
{\phpg\posx2678\pvpg\posy10642\absw7471\absh463 \f10 \fs10 \cf0 \fi6060 \f10 \fs
10 \cf0 rd
\par}{\phpg\posx2678\pvpg\posy10642\absw7471\absh463 \sl-153 \f10 \fs10 \cf0 {\f
s15 Parrott,}{\fs15 E.L.,}{\fs15 1971,}{\i \fs15 Pharmaceutical}{\i \fs15
Technology}{\i \fs15 Fundamental}{\i \fs15 Pharmaceutics}{\fs15 ,}{\fs15
3}{\fs15 Edition,}{\fs15 Burgess }
\par}{\phpg\posx2678\pvpg\posy10642\absw7471\absh463 \sl-290 \f10 \fs10 \cf0 \fi
933 {\fs15 Publishing}{\fs15 Company,}{\fs15 Mineapolis:}{\fs15 Halaman}{\fs1
5 64-66,}{\fs15 73-83. }\par
}
{\phpg\posx2678\pvpg\posy11554\absw7469\absh433 \f10 \fs15 \cf0 \f10 \fs15 \cf0
Pulungan, H., 2004, Membuat Effervescent Tanaman Obat,{\i Trubus}
{\i agrisarana}, Surabaya:
\par}{\phpg\posx2678\pvpg\posy11554\absw7469\absh433 \sl-292 \f10 \fs15 \cf0 \fi
933 Halaman 18-19 \par
}
{\phpg\posx2678\pvpg\posy12432\absw7468\absh431 \f10 \fs15 \cf0 \f10 \fs15 \cf0
Voigt, Rudolf, 1984,{\i Teknologi}{\i Farmasi}, Diterjemahkan oleh Soendari No
erono Soewandhi, Gadjah
\par}{\phpg\posx2678\pvpg\posy12432\absw7468\absh431 \sl-290 \f10 \fs15 \cf0 \fi
933 Mada University Press, Yogyakarta: Halaman 161-162, 553- 555. \par
}
{\phpg\posx9923\pvpg\posy14674\absw281\absh225 \f20 \fs20 \cf0 \f20 \fs20 \cf0 4
8 \par
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