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  • Pa Tho Physiology Gastroenteritis

    Transféré par

    jeneva029
    160 vues2 pages
    This document summarizes the pathophysiology of gastrointestinal infections. It outlines several risk factors, including both modifiable factors like food handling and environment, as well as non-modifiable factors like increased age. Upon ingestion of contaminated food, microorganisms can enter and invade the gastrointestinal tract. This disrupts normal processes and defenses, allowing the microorganisms to release endotoxins and cytokines. This triggers an inflammatory response leading to symptoms like diarrhea, nausea, vomiting, and abdominal pain as the body attempts to fight the infection through fever and increased fluid secretion. If left untreated, this can progress to dehydration and nutritional deficiencies.

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    This document summarizes the pathophysiology of gastrointestinal infections. It outlines several risk factors, including both modifiable factors like food handling and environment, as well as non-modifiable factors like increased age. Upon ingestion of contaminated food, microorganisms can enter and invade the gastrointestinal tract. This disrupts normal processes and defenses, allowing the microorganisms to release endotoxins and cytokines. This triggers an inflammatory response leading to symptoms like diarrhea, nausea, vomiting, and abdominal pain as the body attempts to fight the infection through fever and increased fluid secretion. If left untreated, this can progress to dehydration and nutritional deficiencies.

    Droits d'auteur :

    Attribution Non-Commercial (BY-NC)
    Téléchargez comme DOC, PDF, TXT ou lisez en ligne sur Scribd
    Signaler comme contenu inapproprié
    160 vues2 pages

    Pa Tho Physiology Gastroenteritis

    Transféré par

    jeneva029
    This document summarizes the pathophysiology of gastrointestinal infections. It outlines several risk factors, including both modifiable factors like food handling and environment, as well as non-modifiable factors like increased age. Upon ingestion of contaminated food, microorganisms can enter and invade the gastrointestinal tract. This disrupts normal processes and defenses, allowing the microorganisms to release endotoxins and cytokines. This triggers an inflammatory response leading to symptoms like diarrhea, nausea, vomiting, and abdominal pain as the body attempts to fight the infection through fever and increased fluid secretion. If left untreated, this can progress to dehydration and nutritional deficiencies.

    Droits d'auteur :

    Attribution Non-Commercial (BY-NC)
    Téléchargez comme DOC, PDF, TXT ou lisez en ligne sur Scribd
    Signaler comme contenu inapproprié
    sur 2

    PATHOPHYSIOLOGY

    Risk Factor

    Modifiable Non Modifiable


    Food Handling Increased Age
    Environment
    Use of Antibiotic

    Ingestion of contaminated
    food

    Decreased production
    Disruption of normal
    of hydrochloric acid.

    Decreased gastric and intestinal


    defenses

    Microorganisms enter and invade


    GI tract
    Exogenous
    pyrogen
    Release of Microorganism release
    histamine endotoxins
    Release of
    Activation of Activation of complement and cytokines
    kinins coagulation cascade
    PATHOPHYSIOLOGY
    Disruption of Inhibition of sodium
    osmotic pressure and water reabsorption

    Opsonization and
    Increased protein- rich
    chemotaxis
    fluid secretion
    Stimulates production of Stimulates production
    leukotrienes of prostaglandin
    Vasodilation Decreased ability of
    the intestines to Stimulates of
    reabsorb fluids inflammatory process
    Hypotensi
    on
    Increased fluid volume Abdominal Stimulates
    Alteration in cell hypothalamus
    distention
    wall permeability

    Vagal stimulation Fever


    Alteration
    Diarrhea in water and Hyperactive bowel
    (watery
    electrolyte
    stool) balance sounds
    Pain
    Stimulation of area
    (Abdominal
    postrema cramping)
    Increased secretion of
    Chloride and
    bicarbonate ions in the
    bowel Nausea, anorexia Vomiting

    Continuous active fluid losses, decreased food and


    fluid intake

    Inadequate hydration and


    nutrition

    Weakness, poor skin turgor, dry lips, sunken


    eyeballs

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