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The document contains 8 figures that show measurements and analysis of oxygen, pH, glucose, lactate, glutamine, and amino acid levels across the radius of tumor spheroids. Figure 1 shows that oxygen levels decrease towards the center of spheroids. Figures 2 and 3 show live, dead, and apoptotic cell distributions across spheroid radii. Figure 4 shows that pH decreases towards spheroid centers. Figure 5 shows glucose and lactate levels decrease and increase respectively towards centers, while glutamine decreases and glutamate increases. Figures 6 and 7 show that essential and nonessential amino acid levels decrease towards spheroid centers. Figure 8 compares measurements between large and small spheroids.
The document contains 8 figures that show measurements and analysis of oxygen, pH, glucose, lactate, glutamine, and amino acid levels across the radius of tumor spheroids. Figure 1 shows tha…