IV Morphine Sulfate
(Narcotic Analgesic)
How it works & reason(s)
Client is receiving this
IV Medication
Prescribed Dose & Usual/
Normal dose range for IV
medication & age of client
Usual Rate & Method of
IV Administration
IV–Drug Compatibility
IV-Drug Incompatibility
Dilution &/or need for IV
Flush before/after IV med
administered
Contraindications
Side/Untoward/Adverse
effects/reactions & Antidote,
if one exists
Significant lab values
to assess
Nursing Implications
N22 IV Medication Research Form – 10– JG
Binds to opiate receptors in the CNS. Alters the perception of
and response to painful stimuli while producing generalized
CNS depression
(Reason given: Relief of moderate to severe pain.
Control of postoperative pain in neonates.)
IV injection: 2.5-10mg. Repeat q 2-4 hrs as needed.
Infusion: 0.1-1 mg/mLin NS, D5W. (initial LD may be up to
15mg)
Mechanical Ventilation in Neonates: 50mcg/kg as initial LD
administered over 30-60mins followed with a continuous
infusion of 10-30mcg/kg/hr.
Postoperative analgesia in Neonates: 50mcg/kg as initial
LD administered over 30-60mins followed with a continuous
infusion of 15mcg/kg/hr.
IV injection: 15mg or fraction thereof over 4-5 mins.
Infusion: Rate should be ordered by MD
Compatible with most all meds.
Conflicting compatibility Info = Zovirax, Eraxis, Maxipime,
Lasix, Protonix IV, propofol, and Pentothal)
No listed incompatibilities.
IV injection: may be given undiluted; however, further dilution
with 5 mL od SW or NS to facilitate titration is appropriate.
Infusion: Each 0.1 – 1 mg is usually diluted in 1 mL NS or D5W
and administered vis a controlled infusion device that may be
patient activated.
Acute bronchial asthma, diarrhea caused by
pseudomembranous colitis caused by antibiotics,
hypersensitivity to opiates, resp depression, upper airway
obstruction, premature infants or L & D of premature infant.
confusion, sedation, dizziness, dysphoria, blurred vision,
respiratory depression, hypotension, bradycardia, constipation,
N/V, urinary retention, flushing, itching, sweating
*May ↑ plasma amylase and lipase levels.
*Assess pain (location, type and intensity) prior to and 20 after
IV administration.
*Assess LOC, BP, Pulse, and resp before and after admin.
*Assess bowel sounds periodically after administration.