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SCHEMATIC DIAGRAM

Predisposing Factors Precipitating Factors


• Age = 35 years old • Second Hand Smoker
• Gender = Female • High Protein and Fat intake
• Known Hypertensive • Occupational Hazards
• Occasional Alcoholic Drinker

Genomic Instability

Impaired DNA repair, Aberrant Cell Cycle Control

Enhanced Proliferation

Evasion of Immune System

Invasion of Tissue and Stroma

Ability to recruit vascularization to support growth

Islet-Cell Tumor

INSULINO GASTRINO VIPOM GLUCAGONO SOMATOSTATINO


PPoma
MA MA A MA MA

Adrenergic: Peptic Watery Rash, Diabetes, Watery


palpitations, ulcers, diarrhea, diabetes, cholelithiasi diarrhea,
tremor, enhanced hypokalemia weight loss, s, Body
hunger, acid , anemia steatorrhea, Weakness
sweating secretion hypochlorhy malabsorpti achlorhydria
confusion, dria on, weight , abdominal
seizures, loss pain, weight
transient loss
focal deficit,
coma

Surgical resection Chemotherapy

Whipple Procedure

Distal Pancreatectomy
and Splenectomy

LEGEND
PATHOPHYSIOLOGY Surgical Procedure

Signs and Symptoms Signs and Symptoms Not


Manifested by Patient Manifested by Patient

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