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Question 1. Calculate the drug concentration 0.5 hours after a continuous IV infusion of 12.5
mg/hr has been administered to a patient. Assume a one compartment pharmacokinetic model.
The V and t1/2 values for this drug are 35.9 L and 2.5 hr respectively.

Question 2. Calculate the infusion rate required to achieve a drug concentration of 12 mg/L at 1.5
hours after a continuous IV infusion has been started. Assume a one compartment
pharmacokinetic model. The V and total body clearance values for this drug are 36 L and 8.6
L/hr respectively.

Question 3. Calculate the steady state drug concentration after a continuous IV infusion of 10
mg/hr has been administered to the patient. Assume a one compartment pharmacokinetic model.
The V and total body clearance values for this drug are 30.1 L and 7.1 L/hr respectively.

Question 4. Calculate the infusion rate required to achieve a steady state drug concentration of 6
mg/L. Assume a one compartment pharmacokinetic model. The V and total body clearance
values for this drug are 39.4 L and 9.6 L/hr respectively.










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