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Glycolysis

Aerobic Glycolysis

In the cytoplasm Intermediate in many pathways Preparatory phase

AMP and ATP activate this


enzyme!
(citrate from Krebs inhibits it)

kinase
Adenylate cyclase
2ADP
ATP
AMP + ATP

Less energy means more glycolysis.

Used for shuttling


hydrogen ions into
NADH
mitochondria
(used in oxidative
phosphorylation)

Products of glycolysis
1. 2 moles of ATP
2. 2 moles of NADH Enzyme index
3. 2 moles pyruvate ATP generation 1. Kinases add phosphate
4. (2 moles of water) phase runs twice! 2. Isomerases isomerise the compound
5. (2 moles of hydrogen ions)
3. Dehydrogenases remove hydrogen
4. Mutases move functional groups

Generates 22kJ of energy per


mole of glucose.

Anaerobic Glycolysis

Tissues which respire


anaerobically
1. Mature Erythrocytes
2. Lymphocytes
3. White blood cells
4. Skeletal muscle
5. Skin

Reversed by the Cori Cycle in the liver

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