Etiology Risk Factor

Post-infection (GABHS) ChildrenMale

Antigen-antibody reactions

Goes in the circulation

Traps in glomerulus

Stimulation of hypothalamus
Produce swelling of cells Inflammation process occurs
(heat regulating system)

Activates complement pathways

Narrowing of capillary lumen
fever
Decrease blood flow
Oliguria and increase waste product in the blood
Attack glomerular basement membrane

Decrease GFR

Glomerular proliferation Impedes function of kidney B

C Activation of RAAS

Damage Glomeruli

Irritation on the tissue Scarring occurs Increase capillary permeability

hematuria Excretion of protein and albumin Decrease protein and albumin in th

Decrease GFR

Oliguria and increase waste product in the bloodProteinuria and albuminuria

A
 Decrease protein and albumin in the body
A

Muscle weakness, fatigue and poor appetite Synthesis of lipoprotein Decrease oncotic pressure

hyperlipidemia Fluid shifting C

Decrease fluid in the circulation

RAAS activation

C
 Impedes function of kidney
B
Increase creatinine and potassium
Decrease concentration of urine Decrease erythropoiesis Unable to excrete wastes products

Diminished blood flow Accumulates in the brain

Decrease specific gravity and pH

Hypoxemia to different tissue Decrease GFR seizure

kidney
Acidosis
stomach RAAS activation

Anaerobic metabolism
Hyperventilate constipation

Increase amount of acid

Oliguria and increase waste product in the blood

C
ascites
Compression of diaphragm
Difficulty of breathing
RAAS activation
Sodium and Water Retention
Fluid shifting Increase blood volume
accumulation of fluid in the lung capillaries Generalized edema (ANASARCA) Hypertension
Periorbital edema
Facial edema
Ascites
Pulmonary hypertension Edema on both upper and lower extremities
Increase pulmonary arterial pressure
Rupture of microvascular aneurysm
Hemoptysis