TIEMPO

LOTE 15 20 45 60
3 64.12 81.98 99.88 101.05
3 63.97 74.13 88.99 92.51
3 66.67 78.33 98.76 100.33
3 59.82 71.10 92.29 95.33
3 63.68 78.15 95.27 97.68
3 63.09 73.48 94.50 96.49
3 59.32 75.11 93.44 94.86
3 42.77 55.31 82.23 87.99
3 68.13 81.96 100.85 102.31
3 63.07 77.09 95.47 97.77
3 59.93 76.87 96.80 98.44
3 44.71 56.39 80.27 85.39
5 50.98 60.80 93.24 94.52
5 50.50 67.39 97.14 98.29
5 59.35 71.06 99.14 101.67
5 47.71 62.77 91.13 94.33
5 50.09 64.30 92.89 95.36
5 41.05 53.44 84.92 89.87
5 47.59 62.45 92.16 94.16
5 54.10 67.15 97.78 99.72
5 57.19 77.44 98.79 100.77
5 50.76 66.15 93.88 95.75
5 52.85 78.62 100.89 101.65
5 37.25 51.45 88.00 91.67
n1 12 12 12 12
n2 12 12 12 12
m1 59.94 73.33 93.23 95.85
m2 49.95 65.25 94.16 96.48
m1-m2 9.98833333 8.07333333 -0.93416667 -0.63416667
s21 64.2681818 76.7898636 42.2065174 26.0538265
s22 38.1396697 66.7927424 22.959697 15.3004364

matriz de covarianza m1 LOTE 3

x 64.12 81.98 99.88 101.05
63.97 74.13 88.99 92.51
66.67 78.33 98.76 100.33
59.82 71.10 92.29 95.33
63.68 78.15 95.27 97.68
63.09 73.48 94.50 96.49
59.32 75.11 93.44 94.86
42.77 55.31 82.23 87.99
68.13 81.96 100.85 102.31
63.07 77.09 95.47 97.77
59.93 76.87 96.80 98.44
44.71 56.39 80.27 85.39

xt
64.12 63.97 66.67 59.82 63.68 63.09
81.98 74.13 78.33 71.10 78.15 73.48
 99.88 88.99 98.76 92.29 95.27 94.50
101.05 92.51 100.33 95.33 97.68 96.49

m mt 59.94 73.33
59.94
73.33
93.23
95.85

xt*x
43820.5932 53481.713 67573.0485 69341.1067
53481.713 65363.356 82631.2007 84798.7377
67573.0485 82631.2007 104764.402 107590.663
69341.1067 84798.7377 107590.663 110523.677

m*mT
3592.8036 4395.1005 5588.15625 5744.99925
4395.1005 5376.55563 6836.02865 7027.89573
5588.15625 6836.02865 8691.67752 8935.62717
5744.99925 7027.89573 8935.62717 9186.42377

m1 matriz var cov

((xt*x)-M*Mt*n)/(n-1)
64.2681818 67.3188182 46.8339545 36.4650636
67.3188182 76.7898636 54.4415409 42.1808136
46.8339545 54.4415409 42.2065174 33.0124326
36.4650636 42.1808136 33.0124326 26.0538265

matriz de covarianza m2 LOTE 5

x 50.98 60.80 93.24 94.52
50.50 67.39 97.14 98.29
59.35 71.06 99.14 101.67
47.71 62.77 91.13 94.33
50.09 64.30 92.89 95.36
41.05 53.44 84.92 89.87
47.59 62.45 92.16 94.16
54.10 67.15 97.78 99.72
57.19 77.44 98.79 100.77
50.76 66.15 93.88 95.75
52.85 78.62 100.89 101.65
37.25 51.45 88.00 91.67

xt
50.98 50.50 59.35 47.71 50.09 41.05
60.80 67.39 71.06 62.77 64.30 53.44
93.24 97.14 99.14 91.13 92.89 84.92
94.52 98.29 101.67 94.33 95.36 89.87

m mt 49.95 65.25
49.95
 65.25
94.16
96.48

xt*x
30361.5644 39592.4033 56730.5204 58068.762
39592.4033 51828.0802 74132.6773 75872.77
56730.5204 74132.6773 106653.357 109221.457
58068.762 75872.77 109221.457 111868.99

m*mT
2495.169 3259.4295 4703.61544 4819.3368
3259.4295 4257.78 6144.31444 6295.4808
4703.61544 6144.31444 8866.73334 9084.8784
4819.3368 6295.4808 9084.8784 9308.3904

m2 matriz var cov

((xt*x)-M*Mt*n)/(n-1)
38.1396697 43.5681152 26.1031939 21.5200364
43.5681152 66.7927424 36.4458212 29.7273091
26.1031939 36.4458212 22.959697 18.4469182
21.5200364 29.7273091 18.4469182 15.3004364

MATRIZ DE CORRELACIÓN PARCIAL MC

15 20 45 60

15 51.2039258 55.4434667 36.4685742 28.99255

20 55.4434667 71.791303 45.4436811 35.9540614
45 36.4685742 45.4436811 32.5831072 25.7296754
60 28.99255 35.9540614 25.7296754 20.6771314

INV MC
Spool inv 0.12782833 -0.0691585 -0.00240171 -0.05599157
-0.0691585 0.15649575 -0.14676035 0.00747297
-0.00240171 -0.14676035 1.95005702 -2.16800245
-0.05599157 0.00747297 -2.16800245 2.81164021

DM

(xt-xr)
idem a (m1-m2) 9.98833333
8.07333333
-0.93416667
-0.63416667

(xt-xr) T 9.98833333 8.07333333 -0.93416667 -0.63416667

idem a (m1-m2) T

(xt-xr)T *Spool INV

(m1-m2)T *INV MC 0.75620397 0.70502372 -1.65563769 -0.25670358

(xt-xr) *Spool INV*DMT-(xt-xr)

(m1-m2)T *INV MC*(m1-m2) o DM2 14.9545431

DM 3.86711044

PRUEBA DE HIPÓTESIS DE EQUIVALENCIA ESTADÍSTICA GLOBAL

n 12
p 4
K 1.29545455
CR 19.3729309
Fp,2n-p-1,0.9 o Ftab 2.26630257

NO SON SIMILARES YA QUE CR EXCEDE A Ftab

 se actualiza
se calcula

59.32 42.77 68.13 63.07 59.93 44.71

75.11 55.31 81.96 77.09 76.87 56.39
93.44 82.23 100.85 95.47 96.80 80.27
94.86 87.99 102.31 97.77 98.44 85.39

93.23 95.85

47.59 54.10 57.19 50.76 52.85 37.25

62.45 67.15 77.44 66.15 78.62 51.45
92.16 97.78 98.79 93.88 100.89 88.00
94.16 99.72 100.77 95.75 101.65 91.67

94.16 96.48
 TALLER 8 EVENTO: COMPARACIÓN DE PERFILES DE DISOLUCIÓN
OBJETIVO DETERMINAR MANERA PUNTUAL EL FACTOR SIMILITUD BASADO EN LA DI
DISTANCIA DE MAHALANOBIS

4 TIEMPOS
LOTE LOTE DM gl
2 3 1.41 19 D prom R 2.45333333
2 4 3.76 19 SD 1.19947766
2 5 1.65 19 t0.90,114 1.65832997
3 4 2.84 19
3 5 3.87 19 LIC 0.46
4 5 1.19 19 LSC 4.44
1 5 4.88
glTotales 114
LOTE 1 ES EL DE PRUEBA

TIEMPO
LOTE 15 20 45 60
1 54.83 62.84 93.94 102.92
1 56.16 65.59 91.96 99.82
1 58.85 69.27 96.32 105.92
1 55.39 65.06 89.18 99.31
1 55.09 65.01 97.22 104.73
1 53.98 62.51 89.15 98.92
1
1
51.06
54.85
59.92
63.36
89.71
90.60
96.80
98.34
D M=
1 67.84 77.46 103.98 104.77
1 53.51 63.06 89.84 99.16
1 53.07 62.84 89.39 96.54
1 54.36 63.75 89.55 99.48
5 50.98 60.80 93.24 94.52
5 50.50 67.39 97.14 98.29
5 59.35 71.06 99.14 101.67
5 47.71 62.77 91.13 94.33
5 50.09 64.30 92.89 95.36
5 41.05 53.44 84.92 89.87
5 47.59 62.45 92.16 94.16
5 54.10 67.15 97.78 99.72
2
5
5
57.19
50.76
77.44
66.15
98.79
93.88
100.77
95.75 n
5 52.85 78.62 100.89 101.65 K=
n1
5 37.25
12
51.45
12
88.00
12
91.67
12
2
n2 12 12 12 12
m1 55.75 65.06 92.57 100.56
m2 49.95 65.25 94.16 96.48
m1-m2 5.7975 -0.19583333 -1.59333333 4.07916667
s21 17.9480811 20.286572 20.9142545 10.2331538
s22 38.1396697 66.7927424 22.959697 15.3004364
matriz de covarianza m1 LOTE 1
x 54.83 62.84 93.94 102.92
56.16 65.59 91.96 99.82
58.85 69.27 96.32 105.92
55.39 65.06 89.18 99.31
55.09 65.01 97.22 104.73
53.98 62.51 89.15 98.92
51.06 59.92 89.71 96.80
54.85 63.36 90.60 98.34
67.84 77.46 103.98 104.77
53.51 63.06 89.84 99.16
53.07 62.84 89.39 96.54
54.36 63.75 89.55 99.48

xt
54.83 56.16 58.85 55.39 55.09 53.98
62.84 65.59 69.27 65.06 65.01 62.51
93.94 91.96 96.32 89.18 97.22 89.15
102.92 99.82 105.92 99.31 104.73 98.92

m mt 55.75 65.06
55.75
65.06
92.57
100.56

xt*x
37493.0639 43729.3622 62114.6923 67373.761
43729.3622 51010.2897 72463.5424 78612.8759
62114.6923 72463.5424 103060.516 111841.196
67373.761 78612.8759 111841.196 121458.317

m*mT
3107.96958 3626.8085 5160.70036 5606.08974
3626.8085 4232.26145 6022.21849 6541.96039
5160.70036 6022.21849 8569.2049 9308.76206
5606.08974 6541.96039 9308.76206 10112.146

m1 matriz var cov

((xt*x)-M*Mt*n)/(n-1)
17.9480811 18.8782053 16.9352727 9.15309924
18.8782053 20.286572 17.9018636 9.94102348
16.9352727 17.9018636 20.9142545 12.3683364
9.15309924 9.94102348 12.3683364 10.2331538

matriz de covarianza m2 LOTE 5

x 50.98 60.80 93.24 94.52
50.50 67.39 97.14 98.29
59.35 71.06 99.14 101.67
47.71 62.77 91.13 94.33
 50.09 64.30 92.89 95.36
41.05 53.44 84.92 89.87
47.59 62.45 92.16 94.16
54.10 67.15 97.78 99.72
57.19 77.44 98.79 100.77
50.76 66.15 93.88 95.75
52.85 78.62 100.89 101.65
37.25 51.45 88.00 91.67

xt
50.98 50.50 59.35 47.71 50.09 41.05
60.80 67.39 71.06 62.77 64.30 53.44
93.24 97.14 99.14 91.13 92.89 84.92
94.52 98.29 101.67 94.33 95.36 89.87

m mt 49.95 65.25
49.95
65.25
94.16
96.48

xt*x
30361.5644 39592.4033 56730.5204 58068.762
39592.4033 51828.0802 74132.6773 75872.77
56730.5204 74132.6773 106653.357 109221.457
58068.762 75872.77 109221.457 111868.99

m*mT
2495.169 3259.4295 4703.61544 4819.3368
3259.4295 4257.78 6144.31444 6295.4808
4703.61544 6144.31444 8866.73334 9084.8784
4819.3368 6295.4808 9084.8784 9308.3904

m2 matriz var cov

((xt*x)-M*Mt*n)/(n-1)
38.1396697 43.5681152 26.1031939 21.5200364
43.5681152 66.7927424 36.4458212 29.7273091
26.1031939 36.4458212 22.959697 18.4469182
21.5200364 29.7273091 18.4469182 15.3004364

MATRIZ DE CORRELACIÓN PARCIAL MC

15 20 45 60

15 28.0438754 31.2231602 21.5192333 15.3365678

20 31.2231602 43.5396572 27.1738424 19.8341663
45 21.5192333 27.1738424 21.9369758 15.4076273
 60 15.3365678 19.8341663 15.4076273 12.7667951

INV MC
Spool inv 0.20767591 -0.09703471 -0.09307029 0.01359458
-0.09703471 0.14960467 -0.05749455 -0.04646819
-0.09307029 -0.05749455 0.43870778 -0.32832913
0.01359458 -0.04646819 -0.32832913 0.53043354

DM MODIFICAR EL VECTOR DE DIFERENCIAS DE MED

EN RELACIÓN AL CASO CONSERVADOR DE LOS
(xt-xr) REFERENCIA
idem a (m1-m2) 9.98833333
8.07333333
-0.93416667
-0.63416667

(xt-xr) T 9.98833333 8.07333333 -0.93416667 -0.63416667

idem a (m1-m2) T

(xt-xr)T *Spool INV

(m1-m2)T *INV MC 1.36926461 0.32177137 -1.59540056 -0.2690351

(xt-xr) *Spool INV*DMT-(xt-xr)

(m1-m2)T *INV MC*(m1-m2) o DM2 17.935422

DM FACTOR SIMILITUD 4.23502326

ITUD BASADO EN LA DISTANCIA ESTADÍSTICA MULTIVARIADA

FS

FS
FS

se actualiza
se calcula

T −1
DM= √[ x P−x R S pond
] [ x P−x R ]
2 perfiles son globalmente similares si

2
CR=K×D M ≤F P,2n−p−1,0.9
Donde K:

2
n (2 n− p−1 )
K=
2np ( 2 n−2 )
51.06 54.85 67.84 53.51 53.07 54.36
59.92 63.36 77.46 63.06 62.84 63.75
89.71 90.60 103.98 89.84 89.39 89.55
96.80 98.34 104.77 99.16 96.54 99.48

92.57 100.56
47.59 54.10 57.19 50.76 52.85 37.25
62.45 67.15 77.44 66.15 78.62 51.45
92.16 97.78 98.79 93.88 100.89 88.00
94.16 99.72 100.77 95.75 101.65 91.67

94.16 96.48
E DIFERENCIAS DE MEDIAS
ONSERVADOR DE LOS LOTES DE
 TIEMPO
LOTE 15 20 45 60
1 54.83 62.84 93.94 102.92
1 56.16 65.59 91.96 99.82
1 58.85 69.27 96.32 105.92
1 55.39 65.06 89.18 99.31
1 55.09 65.01 97.22 104.73
1
1
1
1
53.98
51.06
54.85
67.84
62.51
59.92
63.36
77.46
89.15
89.71
90.60
103.98
98.92
96.80
98.34
104.77
DM= √[
1 53.51 63.06 89.84 99.16
1 53.07 62.84 89.39 96.54
1 54.36 63.75 89.55 99.48
5 50.98 60.80 93.24 94.52
5 50.50 67.39 97.14 98.29
5 59.35 71.06 99.14 101.67
5 47.71 62.77 91.13 94.33
5 50.09 64.30 92.89 95.36
5 41.05 53.44 84.92 89.87
5 47.59 62.45 92.16 94.16
5 54.10 67.15 97.78 99.72
2
5
5
57.19
50.76
77.44
66.15
98.79
93.88
100.77
95.75 n (2
5 52.85 78.62 100.89 101.65 K=
n1
5 37.25
12
51.45
12
88.00
12
91.67
12
2n
n2 12 12 12 12
m1 55.75 65.06 92.57 100.56
m2 49.95 65.25 94.16 96.48
m1-m2 5.7975 -0.19583333 -1.59333333 4.07916667
s21 17.9480811 20.286572 20.9142545 10.2331538
s22 38.1396697 66.7927424 22.959697 15.3004364

matriz de covarianza m1 LOTE 1

x 54.83 62.84 93.94 102.92
56.16 65.59 91.96 99.82
58.85 69.27 96.32 105.92
55.39 65.06 89.18 99.31
55.09 65.01 97.22 104.73
53.98 62.51 89.15 98.92
51.06 59.92 89.71 96.80
54.85 63.36 90.60 98.34
67.84 77.46 103.98 104.77
53.51 63.06 89.84 99.16
53.07 62.84 89.39 96.54
54.36 63.75 89.55 99.48

xt
54.83 56.16 58.85 55.39 55.09 53.98
62.84 65.59 69.27 65.06 65.01 62.51
 93.94 91.96 96.32 89.18 97.22 89.15
102.92 99.82 105.92 99.31 104.73 98.92

m mt 55.75 65.06
55.75
65.06
92.57
100.56

xt*x
37493.0639 43729.3622 62114.6923 67373.761
43729.3622 51010.2897 72463.5424 78612.8759
62114.6923 72463.5424 103060.516 111841.196
67373.761 78612.8759 111841.196 121458.317

m*mT
3107.96958 3626.8085 5160.70036 5606.08974
3626.8085 4232.26145 6022.21849 6541.96039
5160.70036 6022.21849 8569.2049 9308.76206
5606.08974 6541.96039 9308.76206 10112.146

m1 matriz var cov

((xt*x)-M*Mt*n)/(n-1)
17.9480811 18.8782053 16.9352727 9.15309924
18.8782053 20.286572 17.9018636 9.94102348
16.9352727 17.9018636 20.9142545 12.3683364
9.15309924 9.94102348 12.3683364 10.2331538

matriz de covarianza m2 LOTE 5

x 50.98 60.80 93.24 94.52
50.50 67.39 97.14 98.29
59.35 71.06 99.14 101.67
47.71 62.77 91.13 94.33
50.09 64.30 92.89 95.36
41.05 53.44 84.92 89.87
47.59 62.45 92.16 94.16
54.10 67.15 97.78 99.72
57.19 77.44 98.79 100.77
50.76 66.15 93.88 95.75
52.85 78.62 100.89 101.65
37.25 51.45 88.00 91.67

xt
50.98 50.50 59.35 47.71 50.09 41.05
60.80 67.39 71.06 62.77 64.30 53.44
93.24 97.14 99.14 91.13 92.89 84.92
94.52 98.29 101.67 94.33 95.36 89.87

m mt 49.95 65.25
49.95
 65.25
94.16
96.48

xt*x
30361.5644 39592.4033 56730.5204 58068.762
39592.4033 51828.0802 74132.6773 75872.77
56730.5204 74132.6773 106653.357 109221.457
58068.762 75872.77 109221.457 111868.99

m*mT
2495.169 3259.4295 4703.61544 4819.3368
3259.4295 4257.78 6144.31444 6295.4808
4703.61544 6144.31444 8866.73334 9084.8784
4819.3368 6295.4808 9084.8784 9308.3904

m2 matriz var cov

((xt*x)-M*Mt*n)/(n-1)
38.1396697 43.5681152 26.1031939 21.5200364
43.5681152 66.7927424 36.4458212 29.7273091
26.1031939 36.4458212 22.959697 18.4469182
21.5200364 29.7273091 18.4469182 15.3004364

MATRIZ DE CORRELACIÓN PARCIAL MC

15 20 45 60

15 28.0438754 31.2231602 21.5192333 15.3365678

20 31.2231602 43.5396572 27.1738424 19.8341663
45 21.5192333 27.1738424 21.9369758 15.4076273
60 15.3365678 19.8341663 15.4076273 12.7667951

INV MC
Spool inv 0.20767591 -0.09703471 -0.09307029 0.01359458
-0.09703471 0.14960467 -0.05749455 -0.04646819
-0.09307029 -0.05749455 0.43870778 -0.32832913
0.01359458 -0.04646819 -0.32832913 0.53043354

DM

(xt-xr)
idem a (m1-m2) 5.7975
-0.19583333
-1.59333333
4.07916667

(xt-xr) T 5.7975 -0.19583333 -1.59333333 4.07916667

idem a (m1-m2) T

(xt-xr)T *Spool INV

(m1-m2)T *INV MC 1.4267503 -0.68979982 -2.56663262 2.77477916

(xt-xr) *Spool INV*DMT-(xt-xr)

(m1-m2)T *INV MC*(m1-m2) o DM2 23.8149587

DM 4.88005724

PRUEBA DE HIPÓTESIS DE EQUIVALENCIA ESTADÍSTICA GLOBAL

n 12
p 4
K 1.29545455
CR 30.8511964
Fp,2n-p-1,0.9 o Ftab 2.26630257

NO SON SIMILARES YA QUE CR EXCEDE A Ftab

TOMA DE DECISIÓN:

CASO 1
EN CASO DE QUE DM PBA - REF SEA MAYOR A LA DM FACTOR SIMILITUD LOS PERFILES NO SON GLOBALMENTE S

CASO 2
EN CASO DE QUE DM PBA - REF SEA MENOR A LA DM FACTOR SIMILITUD
ES NECESARIO CALCULAR EL LÍMITE INFERIOR DE CONFIANZA AL 90% Y EL LÍMITE SUPERIOR DE CONFIANZA AL

LI DM
LS DM

SI EL LS DM ES MENOR A LA DM DEL FACTOR SIMILITUD LOS PERFILES SON GLOBALMENTE SIMILARES

SI EL LS DM ES MAYOR A LA DM DEL FACTOR SIMILITUD LOS PERFILES NO SON GLOBALMENTE SIMILARES
 se actualiza
se calcula

T
√
D M = [ x P−x R ] S−1
pond [ x P −x R ]

2 perfiles son globalmente similares si

2
CR=K×D M ≤F P,2n−p−1,0.9
Donde K:

2
n (2 n− p−1 )
K=
2np ( 2 n−2 )

51.06 54.85 67.84 53.51 53.07 54.36

59.92 63.36 77.46 63.06 62.84 63.75
89.71 90.60 103.98 89.84 89.39 89.55
96.80 98.34 104.77 99.16 96.54 99.48

92.57 100.56

47.59 54.10 57.19 50.76 52.85 37.25

62.45 67.15 77.44 66.15 78.62 51.45
92.16 97.78 98.79 93.88 100.89 88.00
94.16 99.72 100.77 95.75 101.65 91.67

94.16 96.48
S NO SON GLOBALMENTE SIMILARES

PERIOR DE CONFIANZA AL 90% PARA DM PBA REF

ENTE SIMILARES
LMENTE SIMILARES