School of Physical & Mathematical Sciences = NANYANG Division of Chemistry & Biological Chemistry UNIVERSITY H3 Organic Synthesis and Mechanism Stereochemistry utorial 3 1) Sighting along C2-C1 axis, draw the Newman projections of the most stable conformation for the following compounds: 1 HO. cl Do the same as the above but sight along C1-C2 axis. Ase (oe ot & eM. co. H y H x, He yl h 7 # Fe & & 4 0 H 4 n7 cy ou ch Hy Sh ct, on, ch, a oH OH Mac bc Het HTH Me PH Me“ TH a Me on cA ng on ae ey oY rat o ~ toe. we 3) For each of the compounds below, draw the 2 chair conformations: faa aCe re For the 2 skeletal structures above, draw the 2 Newman projections of the 2,ghair conformations by sighting along both C1-C2 and C5-C4. x et 1 f BAL > hy ‘ warn ”School of Physical & Mathematical Sciences = ang Division of Chemistry & Biological Chemistry Gy UNIVERSITY 4) How many sigreciomers ‘are possible for the following compounds? HO te { eo ab : peittions ANN Re] OH fa | ‘OH ts a? . 2*6 ulcer} ole 5) Determine the E/Z configuration for the following alkenes: ei enue 0) L a yo bl% cl) 6) Determine the R/S configuration for all the chiral centres present in the following compounds: cl ye CHs HgC. Yoon” pion Re, Welt Be Hsc“R oie Which compound is achiral? wy, 7) List out all the isomers of C.H-Cl. Identify the pairs of enantiomers and diastereomers. —— FaTeH tome ieee | et AX [ay “dic rtee eT we + 2 woe ele \“ arr of Tr ‘ din tererwes “ Tepe