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Pathophysiology of Acute Gastroenteritis Precipitating factors Lifetsyle Environment Poor Oral Hygiene Diet Etiology Haemophillus influenzae Predisposing

factors Age

Person to person (hands) Ingestion of Pathogens Invasion of pathogens in the GIT Enterotoxin production Interacts with mucosal lining Destruction of epithelial cells

Contaminated food/water

abdominal spasm to limit mucosal injury crampy abdominal pain (continuous destruction Of epithelial cells) nausea

altered peristalsis

reduced absorption of fluid and electrolytes diarrhea dehydration

vomiting loss of fluid and alectrolytes

Inflammation of layer of tissue beneath epithelium of mucosa

increased number of pyrogens

ulceration of mucosa fever melena increased peristaltic movement increased cellular metabolism increased usage of glucose decreased energy level

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