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Hypothalamus Negativ e feedba CR H Pituitary Gland A CTH Adrenal Cortex

High level of ACTH

Insufficient amount of aldosterone being produced

MSH (melanocyte Stimulating Hormone) Melani n

Decrease in Na reabsorption fluid volume in the body

Hyperpigmentat ion
Producing insufficient cortisol

Blood pressure goes down

Causes of adrenal insufficiency: Adrenal dysgenesis Impaired steroidogenesis Adrenal destruction

Addisons disease

Orthostati c hypotensi on

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