EDD INIRODUCTION Poisons Deco (PD 0 hori, dacbirg revdegcrerstic decote clecig abst 1% ofthe populton bore the aze of 65 years The mean prevalence of PD is oppraximatly 160 per 100,000 ord ‘ Incdence 2 per 100,000, ring by saver fl wth age, This consera Is oied at cl praction 2 asset in omving at an cease diogross ard @ ide to he cove of pater, expacaly wih the ovokbiy cf a wider ronger of medication ord theormatc ‘medals ne manager of Pekinsons Diss.HEED CUNICAL DIAGNOSIS OF PARKINSON'S DISEASE: ETE. cuNICAL FEATURES UK BRAIN BANK CRITERIA The cera fordagnass rebated on diicalgardswihbodareda, | arly nonspectic feotres inci ey fatgobily,tachess, mabe, rigidly, tenor ard peeve ratty ashe man cecil Fetes, PO lahogy art ecplin snston in fe lags, bes dererton oad obo dixon tom al tor deordrs ha cout poineonsm, handing rucegrahi, alfa inconcertoten, eel romulsns, se da dean devbonces end aeverl dora mo! och Tis consensus adops he UK Brain Bark Ciera 1992] Fe ee ee ed Step: Diogness of Parkinsonian syndrome Biodsbinova ps tle one of te lowing © Muscat rigiy + Res romor + Poswal nsabiy Sin 2: Exclsion tera inching 4+ Hoy oF repaced aches 1+ istry ef repated heed injuy t 1+ sty of defini encephatis S013: Suppnive prospect citi Unocal onet ew nomex presare Béderce of popresion Pasisen' osyrery Bacon weponse L dopo Swe Ldopnirdicad chovea : 1 dopa response for $+ yea Clrica curse of 10+ yoorsBrodykneta/Alinasa 2 on cbicuto halk fastuw of PD and corelote bes wih he aden! of copaniegic fx Inthe basal ganglia. Ire fo somes of itason ol voliniry movement wit ppoglesve edition in anplivdecrd speed cf rapahive acon Brodykrera oft spooch, inital « lee of rommal lucas of fitch and volme fhypophorc and later dowres of intron ord rrovolorous speech, The sobs tescton tos of erm sing dang walling, ofen asymeanical una « roma agoing. Pax ol faal ghar wih ees ing chsscoly deeb ox 'mesell faces Trove it chacurtealy dcr bed apn’ wih eauerey of {35H ro acu et wren ho Ib sly suspic. Soe in 70% et poten, ly rll and pe nb Fly, ¥ opp sep exon wih ses “omar prodorinart FD has rlavely beter proarls compared to the akineticrigid type al FO. Involvement of ho jaw tegen oc rik moy al accu ow i hess Isletas hc ramos rteva PD, Postal race may be concent cr bo te prodoniran fom cf ronoy.