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Diagram I shows the pathogenesis of type 1 diabetes, which involves a genetic predisposition leading to an environmental insult that triggers an autoimmune response and lymphocyte infiltration of the islets of Langerhans in the pancreas, resulting in the destruction of beta cells and a lack of insulin release, causing insulin dependent diabetes. Diagram II shows the pathogenesis of type 2 diabetes, which can be caused by hereditary factors and obesity, leading to insulin resistance that overworks beta cells and causes their exhaustion and dysfunction, impairing insulin secretion and resulting in hyperglycemia and non-insulin dependent diabetes.
Diagram I shows the pathogenesis of type 1 diabetes, which involves a genetic predisposition leading to an environmental insult that triggers an autoimmune response and lymphocyte infiltration of the islets of Langerhans in the pancreas, resulting in the destruction of beta cells and a lack of insulin release, causing insulin dependent diabetes. Diagram II shows the pathogenesis of type 2 diabetes, which can be caused by hereditary factors and obesity, leading to insulin resistance that overworks beta cells and causes their exhaustion and dysfunction, impairing insulin secretion and resulting in hyperglycemia and non-insulin dependent diabetes.
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Diagram I shows the pathogenesis of type 1 diabetes, which involves a genetic predisposition leading to an environmental insult that triggers an autoimmune response and lymphocyte infiltration of the islets of Langerhans in the pancreas, resulting in the destruction of beta cells and a lack of insulin release, causing insulin dependent diabetes. Diagram II shows the pathogenesis of type 2 diabetes, which can be caused by hereditary factors and obesity, leading to insulin resistance that overworks beta cells and causes their exhaustion and dysfunction, impairing insulin secretion and resulting in hyperglycemia and non-insulin dependent diabetes.
Droits d'auteur :
Attribution Non-Commercial (BY-NC)
Formats disponibles
Téléchargez comme DOCX, PDF, TXT ou lisez en ligne sur Scribd
(14796805 - Journal of Endocrinology) Sclerocarya Birrea (Anacardiaceae) Stem-bark Extract Corrects Glycaemia in Diabetic Rats and Acts on Β-cells by Enhancing Glucose-stimulated Ins