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11 - 17 septembre 2012

11 - 17 septembre 2012

Actualités francophones :

Premier défi voile sur le lac pour six jeunes autistes

Une entreprise de Ris commercialise le concept Snoezelen

Enfants autistes : 5 places de plus au Sessad brévinois

Bientôt un foyer d’accueil réservé aux enfants autistes

A Athis, une nouvelle unité d’intégration au collège Mozart

Bâle: perturbations neuronales liées à l'autisme réversibles

Autisme : le combat d'une mère en colère

Autisme : un festival vendredi pour une cause à (re)découvrir

Un festival autour de l’autisme

Élèves handicapés : rentrée mal anticipée

Vers une politique nationale de l’autisme

Depuis 25 ans au service de l'autisme

Espoir pour les malades

La vitamine B9 réduit le risque d'autisme

Actualités scientifiques internationales :

Predicting the diagnosis of autism spectrum disorder using gene pathway analysis.

Molecular Psychiatry

Altered serotonin, dopamine and norepinepherine levels in 15q duplication and angelman

syndrome mouse models. Plos One

A Double-Blind Placebo Controlled Trial of Ginkgo biloba Added to Risperidone in Patients with Autistic Disorders. Child Psychiatry and Human Development

Prenatal and Postnatal Epigenetic Programming: Implications for GI, Immune, and Neuronal

Function in Autism. Autism Research and Treatment

• ADHD and autism: differential diagnosis or overlapping traits? A selective review. Attention

Deficit and Hyperactivity Disorders

HLA Immune Function Genes in Autism. Autism Research and Treatment

Intracellular and extracellular redox status and free radical generation in primary immune cells from children with autism. Autism Research and Treatment

Experiences of siblings of individuals with autism spectrum disorders. Autism Research and Treatment

Looking through the Same Eyes? Do Teachers' Participation Ratings Match with Ratings of Students with Autism Spectrum Conditions in Mainstream Schools? Autism Research and

Treatment

Living the categorical imperative: autistic perspectives on lying and truth telling-between Kant and care ethics. Medicine, Health Care, and Philosophy

The rubber hand illusion in children with autism spectrum disorders: delayed influence of combined tactile and visual input on proprioception. Autism

Translation and validation of the developmental, dimensional and diagnostic interview (3Di) for diagnosis of autism spectrum disorder in Thai children. Autism

Motor anticipation failure in infants with autism: a retrospective analysis of feeding

situations. Autism

Motor impairment in sibling pairs concordant and discordant for autism spectrum disorders. Autism

Is autism a member of a family of diseases resulting from genetic/cultural mismatches? Implications for treatment and prevention. Autism Research and Treatment

Social Competence Intervention for Parents (SCI-P): Comparing Outcomes for a Parent

Education Program Targeting Adolescents with ASD. Autism Research and Treatment

Mood disorders in mothers of children on the autism spectrum are associated with higher

functioning autism. Autism Research and Treatment

Meta-analysis of studies incorporating the interests of young children with autism spectrum

disorders into early intervention practices. Autism Research and Treatment

• Should we welcome a cure for autism? A survey of the arguments. Medicine, Health Care,

and Philosophy

Toddler autism screening questionnaire: Development and potential clinical validity. Autism

Object interest in autism spectrum disorder: A treatment comparison. Autism

A continuous false belief task reveals egocentric biases in children and adolescents with

Autism Spectrum Disorders. Autism

Brain region-specific glutathione redox imbalance in autism. Neurochemical Research

Geneve Premier défi voile sur le lac pour six jeunes autistes  Isabel Jan-Hess 456 mots

Geneve Premier défi voile sur le lac pour six jeunes autistes

 Isabel Jan-Hess 456 mots 12 septembre 2012

La Tribune de Genève TRIBGN

22

Français Copyright 2012 Edipresse. All Rights Reserved.

La main tremblante, elle pose le pied sur le pont. Les yeux de Yuï, 12 ans, expriment à la fois l’appréhension et le bonheur qui se mêlent dans le cœur de cette jeune autiste. Lundi, c’est à bord d’un voilier encore plus grand qu’elle démarrera le Défi voile du Léman. Cinq jours durant lesquels la jeune fille et cinq de ses copains de La Petite Arche navigueront au gré du petit vent lémanique.

Hier matin, Yuï était accompagnée de David et Julien, tous deux âgés de 14 ans. Attaché à la ceinture, Julien gesticule sur le pont avant du bateau. «Il s’impatiente, il aimerait partir, explique Anne, son éducatrice, qui met à disposition ce voilier familial, amarré à la Nautique. Il adore naviguer. Ça l’apaise, comme la plupart de ces enfants différents. Le bateau a un effet rassurant et contenant. »

Sur le quai, David hésite encore à monter. Mais en fier matelot, il se lance et monte à bord le pied sûr. «C’est un très bon exercice de motricité, précise Yannick, éducateur et moniteur de voile. L’équilibre n’est pas le même sur un sol qui bouge. C’est une sensation très étrange au début. » Après quelques préparatifs, l’équipage largue les amarres et est tiré par un petit remorqueur. «Il y a peu de vent, il nous amène au large et on naviguera ce matin vers la Belotte ou Genthod. » Les enfants regardent le rivage s’éloigner, sourire aux lèvres. David tient la barre pendant que Yannick hisse la voile. Un petit tour avant un pique-nique au large. De quoi ravir ces apprentis matelots.

Depuis plusieurs années déjà, la navigation est au programme des activités de La Petite Arche, institution de la Fondation Ensemble. Un autre équipage participant sera composé d’adultes du foyer L’Essarde, dont la déficience intellectuelle permet l’aventure. Au total, douze voiliers habitables de 40 pieds seront

au départ lundi, ainsi que quatre bateaux d’encadrement et deux goélettes.

Ce premier Défi voile du Léman, qui partira le 17 de Port Choiseul, à Versoix, est organisé par la Fondation Ensemble et l’Association des paralysés de France, qui propose chaque année déjà un défi identique en Bretagne. Une sorte de rallye sur l’eau, menant les équipages à la découverte du Léman en cinq étapes. Jeudi 20, une grande soirée aura lieu au port de Nernier, base, avec la Nautique, des entraînements hebdomadaires.

Note:Horaires et infoswww. apf-defivoilebretagne. org/fondation-ensemble

Après des mois de préparation sur le Léman, David, Julien et Yuï vont passer une semaine à bord d’un voilier

120.0.3011599099.xml

Document TRIBGN0020120912e89c00016

Essonne Une entreprise de Ris commercialise le concept Clément Chaillou 317 mots 12 septembre 2012

Essonne Une entreprise de Ris commercialise le concept

Clément Chaillou 317 mots 12 septembre 2012 Le Parisien-Aujourd'hui en France LEPARI Français Copyright 2012 Le Parisien. All Rights Reserved.

Renouer le contact par l’éveil des sens et la relaxation. C’est ce que propose depuis 2007 Pétrarque, une entreprise de Ris-Orangis, aux personnes atteintes de troubles psychologiques tels que l’autisme ou la maladie d’Alzheimer. Et ce à l’aide d’un outil original : la salle multisensorielle Snoezelen.

Inspiré d’un concept néerlandais né dans les années 1970, l’espace permet de rétablir des liens avec les patients souffrant d’un déficit de communication en faisant appel à la mémoire émotionnelle. La méthode peut également être adaptée aux crèches (lire ci-dessus). Fibre optique, lit à eau vibratoire, petite musique et colonnes à bulles, l’ambiance qui se dégage de la pièce est très particulière. « Le but de l’approche Snoezelen, c’est que la personne puisse lâcher prise pour ensuite l’éveiller sensoriellement », explique Patrice d’Arfeuille, directeur de Pétrarque. Selon le public visé, une salle Snoezelen peut être très différente d’une autre. Mais le résultat, lui, est presque toujours au rendez-vous. « Certaines séances sont très émouvantes, poursuit Patrice d’Arfeuille. Ici, le résidant retrouve une certaine liberté, qu’il n’a pas forcément le reste du temps, et finit par se lâcher. » Un facteur que les établissements médicalisés et autres maisons de retraites ont bien intégré. Principaux clients de la société, ils n’hésitent plus à se lancer dans ce genre d’investissements (de 8000 à 20000 €). « Nous avons installé un espace Snoezelen dans notre centre il y a deux ans sur les conseils de notre psychomotricienne, se souvient Murielle Goudeseune, directrice d’un établissement pour personnes âgées dépendantes à Marcoussis. Le salon se trouve dans l’espace Alzheimer, mais tout le monde peut en profiter. Ça calme beaucoup certains résidants, qui font parfois des crises. Aujourd’hui, c’est un outil qui nous est très utile, presque indispensable. »

Document LEPARI0020120912e89c0004u

Pays de Retz en bref Enfants autistes : 5 places de plus au Sessad brévinois

Pays de Retz en bref Enfants autistes : 5 places de plus au Sessad brévinois

220 mots 12 septembre 2012 Ouest France OUESTF stnazaire Français © Ouest France 2012.

En mai dernier, des parents d'enfants autistes créaient le Collectif pour les enfants autistes de l'Estuaire. Ils étaient en attente de place au Sessad « autisme » de Saint-Brevin-les-Pins ou souhaitaient que le temps d'intervention du Sessad auprès de leur enfant augmente. Le Service d'éducation spéciale et de soins à domicile (Sessad) autisme, dépendant de l'IME de Mindin, est un service public de soins qui intervient sur les lieux de vie de l'enfant, de 0 à 20 ans, dans un rayon de 30 minutes autour de Saint- Brevin, actuellement à raison de moins de trois heures par semaine. « La seule structure publique du département à employer les méthodes comportementales éducatives », explique le collectif.

Suite à leurs actions, l'Agence régionale de santé (ARS) a décidé d'augmenter la capacité du Sessad de 5 places supplémentaires, ce qui la porte à 15 places au total. « Une première avancée pour la prise en charge des enfants sur liste d'attente », souligne le collectif, qui continuera de se battre pour « augmenter le temps de prise en charge des enfants par le Sessad et pour que chaque famille en attente de place puisse espérer avoir une prise en charge dans des délais raisonnables. »

Document OUESTF0020120912e89c0031v

Essonne Bientôt un foyer d’accueil réservé aux enfants autistes l.d. 376 mots 13 septembre 2012

Essonne Bientôt un foyer d’accueil réservé aux enfants autistes

l.d. 376 mots 13 septembre 2012 Le Parisien-Aujourd'hui en France LEPARI Français Copyright 2012 Le Parisien. All Rights Reserved.

draveil

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Un pas en avant de plus dans la prise en charge de l’autisme en Essonne. A Draveil, un foyer d’accueil de quarante places réservées aux enfants touchés par ce trouble du développement verra bientôt le jour. Marie-Arlette Carlotti, ministre déléguée chargée des Personnes handicapées et de la Lutte contre l’exclusion, vient d’apporter son soutien au projet en accordant un financement exceptionnel de 1 M€.

« Le projet est accepté et financé par le gouvernement, c’est un très bon point de départ, se félicite

Thierry Mandon, député PS de la 9e circonscription de l’Essonne. Il faut se féliciter de la création d’une

telle structure dans le département, qui affichait jusqu’alors un vrai déficit dans la prise en charge d’enfants autistes. » Le député-maire de Ris-Orangis avait participé, en juillet, à plusieurs réunions de travail avec Marie-Arlette Carlotti concernant la création de ce foyer d’accueil médicalisé. L’annonce du feu vert donné au lancement du projet intervient alors que le conseil général accueille aujourd’hui une conférence sur l’autisme . Elle mobilisera notamment le centre de ressources autisme Ile-de-France (Craif) et la maison départementale des personnes handicapées (MDPHE).

« Ce projet de foyer s’inscrit pleinement dans le programme national de création de places en

établissements et de services médico-sociaux », se félicite dans un communiqué Jérôme Guedj, le président (PS) du conseil général de l’Essonne. « Cette décision permettra par ailleurs d’accompagner la mutation du site hospitalier Joffre-Dupuytren. »

Un sujet sur lequel Georges Tron, maire (UMP) de Draveil, se dit très attentif. « Ce foyer, dont j’ai porté l’idée par le passé, fait partie du projet de substitution du bâtiment Castor de l’hôpital Dupuytren depuis l’abandon des 240 lits de soins longue durée jugés trop onéreux. C’est une excellente chose que son élaboration se confirme, mais j’attends des garanties sur le maintien des emplois au sein de cet hôpital. »

En juillet, les élus locaux avaient déjà œuvré en faveur des personnes touchées par l’autisme en lançant aux Molières la construction d’un foyer d’accueil médicalisé pour la prise en charge d’adultes.

Document LEPARI0020120913e89d00048

Essonne A Athis, une nouvelle unité d’intégration au collège Mozart M.K. 220 mots 13 septembre

Essonne A Athis, une nouvelle unité d’intégration au collège Mozart

M.K. 220 mots 13 septembre 2012 Le Parisien-Aujourd'hui en France LEPARI Français Copyright 2012 Le Parisien. All Rights Reserved.

.

Le collège Mozart à Athis-Mons accueille depuis cette rentrée une unité localisée pour l’inclusion scolaire (Ulis) des enfants atteints d’autisme. « C’est un véritable projet d’établissement qui nous permet d’envisager sereinement l’intégration des élèves », explique Nicole Dubois, principale de l’établissement. Avec une capacité d’accueil de dix enfants, l’Ulis a ouvert la semaine dernière avec cinq élèves de niveau 6e et un de niveau 5e. Les six ados sont encadrés par une enseignante et un auxiliaire de vie scolaire (AVS) dans une salle avant qu’un éducateur spécialisé ne vienne renforcer le dispositif. Les enfants, qui continuent de bénéficier de soins à l’extérieur du collège, ne sont pas complètement intégrés aux cours généraux. Leurs emplois du temps sont adaptés selon leurs profils et leurs besoins. « Nous allons identifier, pour chaque enfant, un objectif pédagogique particulier », assure la principale.

C’est la deuxième classe adaptée aux autistes qui ouvre dans un collège de l’Essonne, la première ayant été créée au collège Charles-Péguy de Palaiseau. Cinquante-trois enfants dits aux « troubles envahissants du développement » sont scolarisés dans les établissements du département au sein des Ulis pour les collèges et des classes d’inclusion scolaire (Clis) pour l’élémentaire.

Document LEPARI0020120913e89d0004c

Bâle: perturbations neuronales liées à l'autisme réversibles 364 mots 13 septembre 2012 04:31 ATS -

Bâle: perturbations neuronales liées à l'autisme réversibles

364 mots 13 septembre 2012

04:31

ATS - Agence Télégraphique Suisse ATS Français © SDA/ATS Home page address:

http://www.sda.ats.ch

Des chercheurs bâlois ont démontré sur des souris que certaines perturbations des circuits neuronaux consécutives à l'autisme sont réversibles. Ces travaux, considérés comme un pas important vers un traitement médicamenteux, sont publiés dans la revue "Science".

Les autistes souffrent de troubles profonds de développement du cerveau survenant dès la prime enfance. On estime que 1% environ des enfants développent des troubles de type autistique, a indiqué l'Université de Bâle dans un communiqué.

Un facteur de risque central réside dans des mutations de plus d'une centaine de gènes, notamment celui codant la protéine neuroligine-3, qui contribue à la formation des synapses, les points de contact entre les neurones. Les souris chez lesquelles ce gène manque développent des comportements reflétant les principaux aspects de l'autisme .

Effets réversibles

Les équipes des professeurs Peter Scheiffele et Kaspar Vogt, du Biozentrum de l'Université de Bâle, sont parvenus à identifier chez ces rongeurs un défaut de la transmission synaptique des signaux qui perturbe la fonction et la plasticité des circuits neuronaux.

Ils ont constaté que ces effets négatifs vont de pair avec une production accrue d'un récepteur neuronal au glutamate qui module la transmission des signaux entre les neurones. Or un excès de ce récepteur empêche l'adaptation de la transmission des signaux dans les processus d'apprentissage et perturbe à long terme le développement et les fonctions du cerveau.

Après avoir "réenclenché" le gène codant la neuroligine-3 chez les souris autistes , les scientifiques ont constaté que les neurones réduisaient la production du récepteur au glutamate à un niveau normal et que les défauts structurels typiques de l'autisme disparaissaient.

Point d'attaque

Ces récepteurs pourraient donc constituer un point d'attaque pharmacologique pour stopper le développement de l'autisme , voire le rendre réversible, selon les chercheurs. Dans le cadre d'un projet soutenu par l'Union européenne, les deux équipes bâloises travaillent actuellement déjà avec des partenaires de l'industrie au développement de médicaments antagonistes de ce récepteur au glutamate.

Actuellement, l'autisme est incurable. Seuls les symptômes peuvent être atténués par des méthodes pédagogiques et thérapeutiques.

Document ATS0000020120913e89d001xl

Nantes Métropole Autisme : le combat d'une mère en colère Recueilli par 382 mots 13

Nantes Métropole Autisme : le combat d'une mère en colère

Recueilli par 382 mots 13 septembre 2012 Ouest France OUESTF nantes Français © Ouest France 2012.

Le divorce complique parfois la situation des parents d'enfants autistes. Autisme ensemble 44 les soutient.

Témoignage

Bettina, 37 ans, maman de Efflamm, 10 ans, autiste , et de Konogan, 12 ans

« Je suis séparée depuis 2005, divorcée depuis 2009. À l'époque, j'habitais en Ille-et-Vilaine. Mon fils Efflamm, autiste sévère, a été accueilli en hôpital de jour entre 2005 et 2009. Cette prise en charge n'est pas adaptée pour lui. J'ai ensuite déménagé à Nantes. J'avais la garde de mon fils qui allait à l'école, accompagné d'une assistante de vie scolaire. Il fréquentait le centre de loisirs. Il était bien intégré, il faisait des progrès.

Contre toute attente, en décembre 2009, le papa a saisi le juge aux affaires familiales du tribunal de grande instance de Rennes pour transférer la résidence des enfants à son domicile en Bretagne. Mesure prise en dépit du jugement de juin 2009 du tribunal du contentieux de l'incapacité de Rennes décidant

qu'Efflamm devait être orienté en milieu scolaire ordinaire ! Cela a été extrêmement violent. Efflamm est retourné à l'hôpital de jour au lieu de bénéficier d'une rééducation de type comportementaliste selon les recommandations de la Haute autorité de santé. Je le vois un week-end sur deux et la moitié des

vacances scolaires

Il est séparé de son frère qui vit avec moi.

Après plusieurs autres démarches, malgré les préconisations comportementalistes d'un expert de Brest,

j'ai déposé un recours devant la Cour nationale de l'incapacité et de la tarification de l'assurance des

accidents du travail. Efflamm a le droit à une éducation. Mais les années passent

Efflamm ? Quelle place la société réserve à nos enfants autistes ? Je suis soutenue par d'autres parents, qui vivent des situations similaires. Lorsqu'on n'est plus avec son conjoint, on peut avoir des divergences sur la prise en charge de l'enfant. Voilà pourquoi nous avons créé l'association Autisme Ensemble 44. »

Quel avenir aura

Magali GRANDET.

Autisme ensemble 44, 2, route de Clisson, Nantes. tél. 06 04 09 26 45. Rencontre chaque premier jeudi du mois au bar Le Pilori, place du Pilori, à Nantes. E-mail : autismeensemble44@free.fr

Document OUESTF0020120913e89d001lo

Champagnole-région Autisme : un festival vendredi pour une cause à (re)découvrir 312 mots 13 septembre 2012

Champagnole-région Autisme : un festival vendredi pour une cause à (re)découvrir

312 mots

13 septembre 2012 Le Progrès PROGRS

29

Français © 2012 Le Progrès.

Un film, un one-man-show avec une star du café-théâtre, de la musique, l’association Autisme Jura organise vendredi à l’Oppidum un festival qui s’annonce passionnant.

18 h 30

Introduction avec « toi et moi, on s’appelle par nos prénoms », un film de Marc Lavoine qui fait dialoguer des personnalités avec les rédacteurs autistes du journal « Le Papotin ». Ces personnalités se nomment Simone Veil, Marie-José Pérec, Fadela Amara, Ségolène Royal, Marie-George Buffet, Valérie Lemercier, Justine Levy, Roselyne Bachelot, Rama Yade, Cécile Duflot, Mazarine Pingeot et Zazie. Marc Lavoine fait le lien entre le monde des personnalités publiques et celui des personnes atteintes d’autisme et raconte cette histoire… d’humanité ! Suivra un débat avec Driss El Kesri, rédacteur en chef du journal.

19 h 30

Exposition de photos, restauration et buvette animée par le trio Affaire Jazzée, spécialistes locaux de jazz manouche (concert gratuit).

20 h 30

Laurent Savard présentera son spectacle « Le Bal des pompiers ». Humoriste rodé aux cafés-théâtres parisiens qui aborde par l’humour le thème de la différence, celle de son fils Gabin, autiste et hyperactif « son feu d’artifice permanent ». Mais aussi et surtout tous ceux qui croisent son chemin, pédiatre, psy,

potes… tous différents à l’insu de leur plein gré ! Un spectacle salué unanimement par la critique pour son humour résolument neuf, sa performance d’acteur, sa façon d’aborder le rire vis-à-vis du handicap, de la différence.

22 h 30

Concert gratuit de « Léon et les Despérados », groupe créé pour un adolescent différent qui, à travers la musique, se construit un monde à sa mesure. Et aujourd’hui, c’est un adulte qui vous propose de le suivre dans la magie de son ressenti de la scène, du blues et du rock’n’roll.

Document PROGRS0020120913e89d0000s

Champagnole Supp_WE_39 Un festival autour de l’autisme 143 mots 13 septembre 2012 Le Progrès PROGRS

Champagnole

Supp_WE_39

Un festival autour de l’autisme

143 mots

13 septembre 2012 Le Progrès PROGRS

8

Français © 2012 Le Progrès.

Une soirée est programmée, vendredi, à l’Oppidum de Champagnole, avec un festival organisé par l’association Autisme Jura. Un film d’abord, à 18 h 30, « Toi et moi, on s’appelle par nos prénoms », de Marc Lavoine, en présence d’autistes qui réalisentle journal « Le Papotin » et interviewent des personnalités de tous horizons. Un débat suivra avec le rédacteur en chef. Une exposition, un repas

(spécialités au foie gras)et un concert d’Affaire Jazzée suivront, avant le spectaclede Laurent Savard, à 20 h 30. Cet humoriste, réputé dans

l’univers des cafés-théâtres parisiens, a fait un spectacle de l’histoire de sa famille :

son fils Gabin est autiste

hyperactif. Pour clore la soirée, Léon et les Despérados, groupe formé autour d’un jeune autiste , amoureux

du rock’n’roll.

Document PROGRS0020120913e89d0007i

Nantes Métropole Élèves handicapés : rentrée mal anticipée Recueilli par 372 mots 14 septembre 2012

Nantes Métropole Élèves handicapés : rentrée mal anticipée

Recueilli par 372 mots 14 septembre 2012 Ouest France OUESTF nantes Français © Ouest France 2012.

Encore des grains de sable dans l'accompagnement des handicapés à l'école. Certains n'ont pas eu d'AVS à la rentrée.

Témoignage

François Fampou, père d'un enfant de 11 ans, handicapé.

« Mon fils est autiste , scolarisé en CM2 à l'école Sainte-Agnès. Depuis le début de sa scolarité, il a eu un auxiliaire de vie scolaire. Sans elle, il est totalement démuni. Là, la rentrée a commencé depuis dix jours et il n'a toujours pas d'AVS (N.D.L.R. : auxilliare de vie scolaire). En CP, il y avait eu un retard d'un mois. Mais ça pouvait se comprendre, c'était le début du dispositif. Les autres années, il est aussi arrivé qu'il y ait du retard, mais juste une ou deux journées.

En fin de semaine dernière, j'ai commencé à m'énerver. J'ai appelé plusieurs fois à l'Inspection académique. Mon interlocuteur était soit en réunion, soit pas là. Mercredi, j'ai enfin eu quelqu'un à l'Inspection. Et le professeur référent de l'école qui m'a assuré que mon fils aurait un auxiliaire lundi. J'espère que la promesse sera tenue.

Je ne comprends pas pourquoi l'accompagnement des enfants handicapés n'est pas anticipé. Les réunions avec l'équipe de l'école, la Maison départementale du handicap, l'Inspection académique ont eu lieu dès avril-mai pour évaluer les besoins de l'enfant. Et fin juin-début juillet, la Maison départementale

du handicap a délivré la notification des heures nécessaires : 15 h d'auxiliaire de vie scolaire. Alors pourquoi, mon fils n'a personne le jour de la rentrée ?

Sa scolarité, c'est un miracle ! Un miracle qui se produit parce que l'équipe enseignante se mobilise. Parce qu'un des parents réduit son temps de travail. Parce qu'il est accompagné d'un AVS. Mais le miracle est fragile. Un retard et ça casse tout. Et si les parents n'osent pas rouspéter, ce retard peut se transformer en absence.

Pas d'auxiliaire, et c'est un frein à une intégration qui s'amorce. Comme si on donnait un coup de poignard dans ce processus. »

Yasmine TIGOÉ.

Document OUESTF0020120914e89e001yf

suisse Vers une politique nationale de l’autisme 368 mots 15 septembre 2012 24 Heures TFHOUR

suisse Vers une politique nationale de l’autisme

368 mots

15

septembre 2012

24

Heures

TFHOUR

7

Français Copyright 2012 Edipresse. All Rights Reserved.

Pour les parents de l’Association Autisme Suisse, c’est un premier pas important. Et une reconnaissance officielle de leurs difficultés. A travers Claude Hêche, ils ont désormais un porte-voix sous la Coupole. A travers un postulat, signé par près de la moitié des sénateurs, le conseiller aux Etats jurassien demande à la Confédération un plan d’action au niveau national. Interview.

Quelles sont les lacunes dans la prise en charge de l’autisme?

Il n’y a pas de vue d’ensemble, que ce soit pour la détection, le diagnostic, la prise en charge ou le suivi des personnes qui souffrent d’autisme . On disperse nos forces et nos recherches, alors qu’il y a une telle attente de la part des parents, qui se sentent abandonnés. Alain Berset reconnaît que la situation actuelle est insatisfaisante et qu’il faut faire un point au niveau national. Ça ne sert à rien que chaque canton travaille dans son coin. Il faut que la Confédération coordonne l’action.

Vous dites que les parents se sentent abandonnés. Qu’est-ce qui ne fonctionne pas?

C’est un tout. Ce qui manque, en premier lieu, c’est la détection précoce des enfants autistes , c’est d’ailleurs un gros débat. Et puis les moyens alloués pour la prise en charge sont nettement insuffisants. La Suisse a un très gros retard sur une situation aussi grave.

Combien de personnes sont concernées en Suisse?

On n’a aucun recensement des personnes touchées par l’autisme . En faisant des comparaisons

internationales, on peut estimer qu’il y a au moins 50000 personnes concernées par les troubles autistiques

Qu’est-ce qui vous a motivé à vous intéresser à l’autisme ?

Je suis très touché par la souffrance des parents d’autistes. A titre personnel, c’est le cri du cœur d’une maman jurassienne qui m’a poussé à m’engager. Mais ce n’est pas un travail personnel. Ce postulat, nous l’avons préparé ensemble avec les associations concernées. Judith Mayencourt

Le trouble concerne 50 000 personnes en Suisse. Claude Hêche demande à Berne de coordonner la prise en charge

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Depuis 25 ans au service de l'autisme Correspondant 426 mots 17 septembre 2012 Midi Libre

Depuis 25 ans au service de l'autisme

Correspondant 426 mots 17 septembre 2012 Midi Libre MIDLIB ALES Français Copyright 2012 Midi Libre All Rights Reserved

Le vendredi 7 septembre, La Pradelle, l'un des rares établissements français à permettre aux autistes de travailler, fêtait ses 25 ans d'existence.Fondée par Françoise Gremy, aujourd'hui décédé, le centre, inclus dans l'association Sésame Autisme Languedoc, accueille aujourd'hui une centaine de personnes et propose selon, les possibilités et le handicap de chacun, divers ateliers et diverses formes d'accompagnement.Dès la fin de la matinée, de nombreuses personnalités étaient présentes auprès d'Hervé Bonin, directeur de La Pradelle, William Dumas, député de la 5e circonscription, Nelly Frontanau, sa suppléante et conseillère régionale, Francis Maurin, conseiller général du canton de Saint-André-de- Valborgne, Aline Combes, représentante de l'agence régionale de santé, Jean-Louis Vidal, président de l'association sésame Autisme Languedoc, et les présidents de diverses associations.

Un des cinq établissements accueillant des autistes À leur côté, familles et amis des pensionnaires ainsi que certains d'entre eux étaient rassemblés pour écouter les différents discours relatant l'historique de La Pradelle et surtout mettant en évidence la nécessité et les résultats positifs de cet Ésat (Établissement services d'aide par le travail).L'émotion fut à son comble lorsque le micro fut confié à quelques pensionnaires qui ont raconté leur quotidien, leur travail, leur relation avec le personnel d'encadrement et le bonheur de cette liberté et de cette dignité devenues réalité.Les productions du lieu ; jus de pommes ou de poires, charcuterie et autres délices, furent servis lors de l'apéritif sous les ombrages.L'après-midi, les portes se sont ouvertes et chacun a pu découvrir les ateliers et les divers produits fabriqués à La Pradelle, sous l'œil fier et le sourire affiché par les autistes présents.

Aides de l'État en baisse Le soir, le repas a rassemblé près de 250 convives ; repas préparé par Les disciples d'Escoffier, association pour la transmission et l'évolution de la cuisine.Il ne faut pas oublier qu'il y a en France 1 400 Ésat et ces établissements permettent à 115 000 handicapés de travailler, sans ces

établissements, ils n'auraient aucune place dans la société.Seulement cinq Ésat accueillent des autistes, mais, hélas, les aides de l'État sont en inquiétante diminution et ces structures rencontrent de plus en plus de difficultés. Elles pourraient un jour être menacées malgré le fait que, grâce à elles, le soleil entre dans le cœur de nombreux autistes et dans celui de leurs proches.

Correspondant M L : 06 47 29 81 90.

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Suisse Espoir pour les malades Sipa/C.Z. 165 mots 17 septembre 2012 La Tribune de Genève

Suisse Espoir pour les malades

Sipa/C.Z.

165 mots

17 septembre 2012 La Tribune de Genève TRIBGN

5

Français Copyright 2012 Edipresse. All Rights Reserved.

UDes chercheurs bâlois ont remis en place, chez les souris, les déficiences neuronales qui seraient à l’origine de l’autisme.

Les personnes autistes sont atteintes, dès leur prime enfance, de perturbations dans le développement du cerveau. Des chercheurs du Biozentrum de l’Université de Bâle ont pu mettre en évidence sur des souris un dysfonctionnement dans les connexions neuronales qui serait spécifique à cette maladie.

Selon les résultats publiés dans la revueScience, ils sont également parvenus à remettre en bon état de marche la fonction déficiente constatée.

Selon les chercheurs, il est très important d’avoir pu mettre en évidence que les perturbations neuronales sont réversibles. Il s’agit d’un pas important en direction d’une thérapie de l’autisme avec des médicaments – que ce soit pour stopper le développement de la perturbation, voire pour l’inverser. Actuellement, seules les manifestations de la maladie peuvent être traitées par des mesures pédagogiques.

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Votre Vie La vitamine B9 réduit le risque d'autisme

RICHARD BÉLIVEAU 675 mots 17 septembre 2012

Le Journal de Montréal JNLMTR Final

59

Français 2012 Sun Media Corporation

La prise d'acide folique pendant la grossesse est très importante pour le développement neurologique du futur enfant. Une étude récente suggère que cette vitamine pourrait aussi diminuer le risque d'autisme.

On estime que 1 enfant sur 150 souffre de troubles envahissants du développement (TED), le plus connu de ces troubles étant l'autisme.

TED

Cette affection, qui se manifeste généralement vers l'âge de 18 ou 24 mois, touche principalement les garçons (4 à 5 fois plus que les filles) et perturbe en profondeur le développement et le fonctionnement de l'enfant. Les symptômes autistiques peuvent varier considérablement d'un enfant à l'autre, mais ils se caractérisent globalement par des problèmes de communication, par des interactions sociales déficientes, ainsi que des intérêts et comportements restreints ou répétitifs.

UN TROUBLE COMPLEXE

L'autisme est un trouble complexe dont les causes demeurent mal comprises. Une composante génétique héréditaire est clairement établie puisque les jumeaux identiques sont simultanément touchés par ce trouble, et que les frères et soeurs d'un autiste sont également plus à risque. Les travaux réalisés jusqu'à présent suggèrent que des mutations dans certains gènes responsables de la communication entre les neurones au niveau des synapses peuvent participer au développement de l'autisme . L'influence exacte de ces gènes demeure cependant difficile à établir étant donné que jusqu'à 1000 gènes distincts pourraient être impliqués, interagissant entre eux sous l'influence de différents facteurs du

mode de vie pour favoriser le développement de ce trouble. De plus, certains gènes soupçonnés de causer l'autisme apparaissent fréquemment en absence de gènes parentaux défectueux, suggérant que l'altération de ces gènes s'est produite lors du développement de l'enfant. L'autisme est donc une maladie complexe, dont le développement peut être influencé par une panoplie de facteurs.

INFLUENCE IN UTERO

On soupçonne depuis plusieurs années que l'autisme se développe très tôt, possiblement lors de la formation du système nerveux au cours du premier mois de grossesse. Il est donc possible que certains facteurs reconnus pour influer sur le développement neurologique de l'enfant puissent également exercer un impact positif sur le risque d'autisme .

L'acide folique (vitamine B9), présent en grandes quantités dans les légumes verts, est essentiel à la croissance des neurones et au développement du système nerveux. Comme l'apport de cette vitamine est souvent trop faible dans l'alimentation moderne, on conseille aux femmes enceintes de prendre des suppléments d'acide folique pour réduire le risque de malformations du tube neural comme l'anencéphalie et le spina-bifida. Cette recommandation a d'ailleurs eu une influence extraordinaire sur l'incidence de ces malformations, les études montrant une réduction de 70 % des défauts du tube neural depuis son implantation.

Pour déterminer la relation entre l'apport en acide folique et le risque d'autisme, des chercheurs ont analysé l'alimentation et la supplémentation de 429 mères d'enfants d'âge préscolaire atteints d'autisme et de 278 mères d'enfants dont le développement était normal. Ils ont observé que les mères d'enfants normaux ont eu des apports plus importants d'acide folique durant leur grossesse que les mères d'enfants autistes. Globalement, les données indiquent qu'un apport moyen d'acide folique quotidien supérieur à 600 micro g au cours du premier trimestre est associé à une diminution de 40 % du risque

d'autisme1.

Ces observations sont capitales, car elles identifient pour la première fois un facteur de risque d'autisme qui peut être modulé par le mode de vie. Il faut toutefois se rappeler que la demande du foetus en acide folique est la plus élevée au cours du premier mois de grossesse, une période où la future mère ignore souvent qu'elle est enceinte. Pour les femmes qui tentent de tomber enceinte, l'adoption d'une alimentation riche en acide folique (légumes verts, légumineuses) pourrait constituer une excellente façon

de veiller au maintien de leur santé

et de celle de leur futur enfant.

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FED:Genetic test for autism developed 467 mots 12 septembre 2012 Australian Associated Press General News

FED:Genetic test for autism developed

467 mots

12 septembre 2012

Australian Associated Press General News AAP Anglais (c) 2012 Australian Associated Press Pty Ltd. All Rights Reserved

AUTISM By Michelle Henderson, AAP National Medical Writer

MELBOURNE, Sept 12 AAP - Australian researchers have developed the first known genetic test to predict the risk of children developing an autism spectrum disorder (ASD).

Further studies are needed before the blood test becomes available, which could take another five years,

but researchers say early results indicate the test can predict the likelihood of developing an ASD with a

72 per cent success rate.

The team of researchers led by the University of Melbourne made another significant finding, published in the journal Molecular Psychiatry this week, that could potentially lead to drug treatments for ASD.

The scientists identified genes that protect against ASD, in addition to genes linked to an increased risk of the disorders.

Both would be used in the genetic test to produce a higher or lower risk of developing autism, a condition characterised by abnormal social interaction, impaired communication and repetitive behaviours.

Lead researcher Professor Stan Skafidas from the University of Melbourne said it may be possible in future to harness those protective genes to develop new pharmacological treatments.

The genetic test could help clinicians provide treatment earlier to children and reduce the lengthy time it currently takes to diagnose the disorders.

However, Prof Skafidas conceded that the 72 per cent accuracy of the test meant a third of children tested could be misdiagnosed and either not go on to develop an ASD or develop a disorder the test had failed to predict.

He said the study had also shown that genetics played a significant part in autism, although other factors could also be involved.

Western Health neuropsychologist Dr Renee Testa said diagnosing ASD was a lengthy and costly process that put significant pressure on both parents and children, which a genetic test could potentially alleviate.

"If there is a possibility of having an early marker that can help us monitor these children for any significant signs of ASD then I think that would be a significant help," she said.

Stephanie Baker, 33, said having a genetic test could have helped diagnose her two young boys earlier with an autism spectrum disorder.

Three-year-old Hamish was diagnosed with autism when he was two, while Robert, 5, was only diagnosed with Asperger's Syndrome three months after turning five.

"The earlier you can diagnose, the better," she told AAP.

"I probably would have got somewhere with him (Robert) a couple of years sooner if there was something like this."

The study used data from about 7,000 people with autism and identified 237 genetic markers in 146 genes.

About one in 150 children have an ASD, affecting about 120,000 Australians.

Researchers from Monash University, Melbourne Health and Austin Health were also involved in the study.

AAP md/bec/de

Document AAP0000020120912e89c000um

Autism; Research Results from Department of Neurology Update Understanding of Autism

411 mots 14 septembre 2012

Chemicals & Chemistry CHEMEC

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2012 SEP 14 (VerticalNews) -- By a News Reporter-Staff News Editor at Chemicals & Chemistry -- Researchers detail new data in Autism. According to news reporting from Memphis, Tennessee, by VerticalNews journalists, research stated, "Childhood neurodevelopmental disorders like Angelman syndrome and autism may be the result of underlying defects in neuronal plasticity and ongoing problems with synaptic signaling. Some of these defects may be due to abnormal monoamine levels in different regions of the brain."

The news correspondents obtained a quote from the research from the Department of Neurology, "Ube3a, a gene that causes Angelman syndrome (AS) when maternally deleted and is associated with autism when maternally duplicated has recently been shown to regulate monoamine synthesis in the Drosophila brain. Therefore, we examined monoamine levels in striatum, ventral midbrain, frontal cerebral cortex, cerebellar cortex and hippocampus in Ube3a deficient and Ube3a duplication animals. We found that serotonin (5HT), a monoamine affected in autism, was elevated in the striatum and cortex of AS mice. Dopamine levels were almost uniformly elevated compared to control littermates in the striatum, midbrain and frontal cortex regardless of genotype in Ube3a deficient and Ube3a duplication animals. In the duplication 15q autism mouse model, paternal but not maternal duplication animals showed a decrease in 5HT levels when compared to their wild type littermates, in accordance with previously published data. However, maternal duplication animals show no significant changes in 5HT levels throughout the brain."

According to the news reporters, the researchers concluded: "These abnormal monoamine levels could be responsible for many of the behavioral abnormalities observed in both AS and autism, but further investigation is required to determine if any of these changes are purely dependent on Ube3a levels in the brain."

For more information on this research see: Altered serotonin, dopamine and norepinepherine levels in 15q duplication and angelman syndrome mouse models. Plos One, 2012;7(8):e43030. (Public Library of Science - www.plos.org; Plos One - www.plosone.org)

Our news journalists report that additional information may be obtained by contacting M.F. Farook, Dept. of Neurology, UTHSC, Memphis, Tennessee, United States.

Keywords for this news article include: Brain, Autism, Memphis, Dopamine, Tennessee, Neurology, United States, Catecholamines, Biogenic Amines, Angelman Syndrome, Organic Chemicals, Movement Disorders, Chromosome Disorders, Congenital Abnormalities, North and Central America, Developmental Disabilities, Central Nervous System Diseases.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2012, NewsRx LLC

Document CHEMEC0020120907e89e001o1

Autism; Data on Autism Discussed by Researchers at Tehran University of Medical Sciences

415 mots 14 septembre 2012

Chemicals & Chemistry CHEMEC

1488

Anglais © Copyright 2012 Chemicals & Chemistry via NewsRx.com

2012 SEP 14 (VerticalNews) -- By a News Reporter-Staff News Editor at Chemicals & Chemistry -- Investigators publish new report on Autism. According to news reporting from Tehran, Iran, by VerticalNews journalists, research stated, "Ginkgo biloba has been reported to affect the neurotransmitter system and to have antioxidant properties that could impact the pathogenesis of Autism Spectrum Disorder. Based on these studies, we decided to assess the effectiveness of Ginkgo biloba extract (Ginko T.D., Tolidaru, Iran) as an adjunctive agent to risperidone in the treatment of autism."

The news correspondents obtained a quote from the research from the Tehran University of Medical Sciences, "Forty-seven outpatients with a DSM-IV-TR diagnosis of autism ages between 4 and 12 years were assigned to this double blinded clinical trial and were randomly divided into two groups. One group received risperidone plus Ginko T.D and the other received risperidone plus placebo. The dose of risperidone was 1-3 mg/day and the dose of Ginko T.D. was 80 mg/day for patients under 30 kg and 120 mg/day for patients above 30 kg. Patients were assessed using Aberrant Behavior Checklist-Community (ABC-C) rating scale and the side effect check list every 2 weeks until the endpoint. None of the 5 subscales of ABC-C rating scale showed significant differences between the two groups. Incidents of side effects were not significantly different between the two groups. Adding Ginkgo biloba to risperidone did not affect the treatment outcome of ADs."

According to the news reporters, the researchers concluded: "Nevertheless, further observations are needed to confirm this result."

For more information on this research see: A Double-Blind Placebo Controlled Trial of Ginkgo biloba Added to Risperidone in Patients with Autistic Disorders. Child Psychiatry and Human Development, 2012;43(5):674-82. Child Psychiatry and Human Development can be contacted at: Springer, 233 Spring Street, New York, NY 10013, USA.

Our news journalists report that additional information may be obtained by contacting E. Hasanzadeh, Psychiatric Research Center, Roozbeh Psychiatric Hospital, Tehran University of Medical Sciences, South Kargar Street, 13337, Tehran, Iran.

Publisher contact information for the journal Child Psychiatry and Human Development is: Springer, 233 Spring Street, New York, NY 10013, USA.

Keywords for this news article include: Iran, Asia, Tehran, Autism, Neurology, Developmental Disabilities.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2012, NewsRx LLC

Document CHEMEC0020120907e89e000go

Autism; Findings from Sultan Qaboos University in Autism Reported

387 mots

17 septembre 2012 Mental Health Weekly Digest MHWK

30

Anglais © Copyright 2012 Mental Health Weekly Digest via NewsRx.com

2012 SEP 17 (NewsRx) -- By a News Reporter-Staff News Editor at Mental Health Weekly Digest -- Investigators discuss new findings in Autism. According to news reporting originating in Muscat, Oman, by NewsRx journalists, research stated, "Although autism is first and foremost a disorder of the central nervous system, comorbid dysfunction of the gastrointestinal (GI) and immune systems is common, suggesting that all three systems may be affected by common molecular mechanisms. Substantial systemic deficits in the antioxidant glutathione and its precursor, cysteine, have been documented in autism in association with oxidative stress and impaired methylation."

The news reporters obtained a quote from the research from Sultan Qaboos University, "DNA and histone methylation provide epigenetic regulation of gene expression during prenatal and postnatal development. Prenatal epigenetic programming (PrEP) can be affected by the maternal metabolic and nutritional environment, whereas postnatal epigenetic programming (PEP) importantly depends upon nutritional support provided through the GI tract. Cysteine absorption from the GI tract is a crucial determinant of antioxidant capacity, and systemic deficits of glutathione and cysteine in autism are likely to reflect impaired cysteine absorption. Excitatory amino acid transporter 3 (EAAT3) provides cysteine uptake for GI epithelial, neuronal, and immune cells, and its activity is decreased during oxidative stress. Based upon these observations, we propose that neurodevelopmental, GI, and immune aspects of autism each reflect manifestations of inadequate antioxidant capacity, secondary to impaired cysteine uptake by the GI tract."

According to the news reporters, the researchers concluded: "Genetic and environmental factors that adversely affect antioxidant capacity can disrupt PrEP and/or PEP, increasing vulnerability to autism."

For more information on this research see: Prenatal and Postnatal Epigenetic Programming: Implications for GI, Immune, and Neuronal Function in Autism. Autism Research and Treatment, 2012;2012():190930. (Hindawi Publishing - www.hindawi.com; Autism Research and Treatment -

Our news correspondents report that additional information may be obtained by contacting M.I. Waly, Dept. of Food Science and Nutrition, Sultan Qaboos University, Alkoudh 123, Muscat, Oman.

Keywords for this news article include: Oman, Asia, Antioxidants, Cells, Muscat, Autism, Neurons, Cysteine, Genetics, Neurology, Protective Agents, Sulfur Amino Acids, Neutral Amino Acids, Sulfhydryl Compounds, Developmental Disabilities.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2012, NewsRx LLC

Document MHWK000020120914e89h00008

Asperger Syndrome; Reports from University of Wurzburg Advance Knowledge in Asperger Syndrome

346 mots 17 septembre 2012

Mental Health Weekly Digest

MHWK

50

Anglais

© Copyright 2012 Mental Health Weekly Digest via NewsRx.com

2012 SEP 17 (NewsRx) -- By a News Reporter-Staff News Editor at Mental Health Weekly Digest -- Current study results on Asperger syndrome have been published. According to news originating from Wurzburg, Germany, by NewsRx correspondents, research stated, "According to DSM-IV TR and ICD-10,

a diagnosis of autism or Asperger Syndrome precludes a diagnosis of attention-deficit/hyperactivity

disorder (ADHD). However, despite the different conceptualization, population-based twin studies reported symptom overlap, and a recent epidemiologically based study reported a high rate of ADHD in autism and autism spectrum disorders (ASD)."

Our news journalists obtained a quote from the research from the University of Wurzburg, "In the planned revision of the DSM-IV TR, dsm5 (www.dsm5.org), the diagnoses of autistic disorder and ADHD will not be mutually exclusive any longer. This provides the basis of more differentiated studies on overlap and distinction between both disorders. This review presents data on comorbidity rates and symptom overlap and discusses common and disorder-specific risk factors, including recent proteomic studies. Neuropsychological findings in the areas of attention, reward processing, and social cognition are then compared between both disorders, as these cognitive abilities show overlapping as well as specific impairment for one of both disorders. In addition, selective brain imaging findings are reported. Therapeutic options are summarized, and new approaches are discussed."

According to the news editors, the researchers concluded: "The review concludes with a prospectus on open questions for research and clinical practice."

For more information on this research see: ADHD and autism: differential diagnosis or overlapping traits?

A selective review. Attention Deficit and Hyperactivity Disorders, 2012;4(3):115-39.

The news correspondents report that additional information may be obtained from R. Taurines, Dept. of

Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Wurzburg University, Wurzburg, Germany.

Keywords for this news article include: Europe, Autism, Germany, Wurzburg, Neurology, Asperger Syndrome, Developmental Disabilities, Attention Deficit Hyperactivity Disorders.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2012, NewsRx LLC

Document MHWK000020120914e89h0000v

Autism; Reports from Utah State University Advance Knowledge in Autism

320 mots

17 septembre 2012 Mental Health Weekly Digest MHWK

51

Anglais © Copyright 2012 Mental Health Weekly Digest via NewsRx.com

2012 SEP 17 (NewsRx) -- By a News Reporter-Staff News Editor at Mental Health Weekly Digest -- Data detailed on Autism have been presented. According to news reporting from Logan, Utah, by NewsRx journalists, research stated, "The human leukocyte antigen (HLA) genes on chromosome 6 are instrumental in many innate and adaptive immune responses. The HLA genes/haplotypes can also be involved in immune dysfunction and autoimmune diseases."

The news correspondents obtained a quote from the research from Utah State University, "It is now becoming apparent that many of the non-antigen-presenting HLA genes make significant contributions to autoimmune diseases. Interestingly, it has been reported that autism subjects often have associations with HLA genes/haplotypes, suggesting an underlying dysregulation of the immune system mediated by HLA genes. Genetic studies have only succeeded in identifying autism-causing genes in a small number of subjects suggesting that the genome has not been adequately interrogated. Close examination of the HLA region in autism has been relatively ignored, largely due to extraordinary genetic complexity."

According to the news reporters, the researchers concluded: "It is our proposition that genetic polymorphisms in the HLA region, especially in the non-antigen-presenting regions, may be important in the etiology of autism in certain subjects."

For more information on this research see: HLA Immune Function Genes in Autism. Autism Research and Treatment, 2012;2012():959073. (Hindawi Publishing - www.hindawi.com; Autism Research and Treatment - www.hindawi.com/journals/aurt/)

Our news journalists report that additional information may be obtained by contacting A.R. Torres, Center for Persons with Disabilities, Utah State University, 6804 Old Main Hill, Logan, UT 84322, United States.

Keywords for this news article include: Utah, Logan, Autism, Genetics, Neurology, United States, North

and Central America, Developmental Disabilities.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2012, NewsRx LLC

Document MHWK000020120914e89h0000w

Autism; Researchers from University of Arkansas for Medical Sciences Report Recent Findings in Autism

405 mots 17 septembre 2012

Mental Health Weekly Digest MHWK

62

Anglais © Copyright 2012 Mental Health Weekly Digest via NewsRx.com

2012 SEP 17 (NewsRx) -- By a News Reporter-Staff News Editor at Mental Health Weekly Digest -- Investigators publish new report on Autism. According to news reporting originating in Little Rock, Arkansas, by NewsRx journalists, research stated, "The modulation of the redox microenvironment is an important regulator of immune cell activation and proliferation. To investigate immune cell redox status in autism we quantified the intracellular glutathione redox couple (GSH/GSSG) in resting peripheral blood mononuclear cells (PBMCs), activated monocytes and CD4 T cells and the extracellular cysteine/cystine redox couple in the plasma from 43 children with autism and 41 age-matched control children."

The news reporters obtained a quote from the research from the University of Arkansas for Medical Sciences, "Resting PBMCs and activated monocytes from children with autism exhibited significantly higher oxidized glutathione (GSSG) and percent oxidized glutathione equivalents and decreased glutathione redox status (GSH/GSSG). In activated CD4 T cells from children with autism, the percent oxidized glutathione equivalents were similarly increased, and GSH and GSH/GSSG were decreased. In the plasma, both glutathione and cysteine redox ratios were decreased in autistic compared to control children. Consistent with decreased intracellular and extracellular redox status, generation of free radicals was significantly elevated in lymphocytes from the autistic children. These data indicate primary immune cells from autistic children have a more oxidized intracellular and extracellular microenvironment and a deficit in glutathione-mediated redox/antioxidant capacity compared to control children."

According to the news reporters, the researchers concluded: "These results suggest that the loss of glutathione redox homeostasis and chronic oxidative stress may contribute to immune dysregulation in autism."

For more information on this research see: Intracellular and extracellular redox status and free radical generation in primary immune cells from children with autism. Autism Research and Treatment,

2012;2012():986519. (Hindawi Publishing - www.hindawi.com; Autism Research and Treatment - www.hindawi.com/journals/aurt/)

Our news correspondents report that additional information may be obtained by contacting S. Rose, Dept. of Pediatrics, Arkansas Children's Hospital Research Institute, University of Arkansas for Medical Sciences, Little Rock, AR 72202, United States.

Keywords for this news article include: Autism, Arkansas, Neurology, Little Rock, Glutathione, United States, Free Radicals, Oligopeptides, Inorganic Chemicals, North and Central America, Developmental Disabilities.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2012, NewsRx LLC

Document MHWK000020120914e89h00019

Autism; Findings from Illinois State University Advance Knowledge in Autism

287 mots

17 septembre 2012 Mental Health Weekly Digest MHWK

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Anglais © Copyright 2012 Mental Health Weekly Digest via NewsRx.com

2012 SEP 17 (NewsRx) -- By a News Reporter-Staff News Editor at Mental Health Weekly Digest -- Current study results on Autism have been published. According to news originating from Normal, Illinois, by NewsRx correspondents, research stated, "The purpose of this study was to explore the experiences of siblings of individuals with autism spectrum disorders (ASDs) and identify their self-reported support needs. We conducted in-person semi-structured interviews with 12 siblings aged 7 to 15 of children aged 6 to 15 with ASDs."

Our news journalists obtained a quote from the research from Illinois State University, "Employing a qualitative collective case study research method, we conducted cross-case analyses to address our research questions. Three major themes emerged: (a) descriptions of the sibling subsystem (b) cohesion between and among the siblings, and (c) adaptability of the participant siblings to having family members with ASDs."

According to the news editors, the researchers concluded: "Discussion of these findings and recommendations for future research contributes to the existing literature on siblings of children with disabilities."

For more information on this research see: Experiences of siblings of individuals with autism spectrum disorders. Autism Research and Treatment, 2012;2012():949586. (Hindawi Publishing - www.hindawi.com; Autism Research and Treatment - www.hindawi.com/journals/aurt/)

The news correspondents report that additional information may be obtained from M.E. Angell, Dept. of Special Education, Campus Box 5910, Illinois State University, Normal, IL 61790-5910, United States.

Keywords for this news article include: Normal, Autism, Illinois, Neurology, Pediatrics, United States, North and Central America, Developmental Disabilities.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2012, NewsRx LLC

Document MHWK000020120914e89h00029

Science; Investigators at Department of Education Publish New Data on Science

374 mots

17 septembre 2012 Mental Health Weekly Digest MHWK

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2012 SEP 17 (NewsRx) -- By a News Reporter-Staff News Editor at Mental Health Weekly Digest -- Investigators publish new report on Science. According to news reporting from Norrkoping, Sweden, by NewsRx journalists, research stated, "To create an inclusive classroom and act accordingly, teachers' understanding of the experiences of participation of students with autism spectrum conditions (ASCs) is crucial. This understanding may depend on the teachers' professional experiences, support and personal interests."

The news correspondents obtained a quote from the research from the Department of Education, "The aim of the present questionnaire study was to investigate how well the teachers' ratings of their students with ASCs' perception of participation matched with the students' own ratings. Furthermore, possible correlations between the accuracy of teachers' ratings and the teachers' self-reported professional experience, support (including support-staff), and personal interest were investigated. Teachers' ratings were also used to examine how their understandings correlated with classroom actions. The agreements between teachers' and students' ratings were moderate to high, and the ability to attune to the students' perception of participation was not affected by the presence of a support-staff. The teachers' personal interest in teaching students with ASC correlated with their accuracy, suggesting that this is a factor to consider when planning for successful placements in mainstream schools."

According to the news reporters, the researchers concluded: "Teachers' understandings of the students with ASCs' perception of being bullied or unpopular correlated with implementation of activities to improve the attitudes of classmates, but not with actions to enhance social relations for the students with ASC."

For more information on this research see: Looking through the Same Eyes? Do Teachers' Participation Ratings Match with Ratings of Students with Autism Spectrum Conditions in Mainstream Schools? Autism Research and Treatment, 2012;2012():656981. (Hindawi Publishing - www.hindawi.com; Autism Research and Treatment - www.hindawi.com/journals/aurt/)

Our news journalists report that additional information may be obtained by contacting M. Falkmer, Dept. of Education, Municipality Council of Norrkoping, Norrkoping, Sweden.

Keywords for this news article include: Sweden, Europe, Autism, Science, Neurology, Norrkoping, Developmental Disabilities.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2012, NewsRx LLC

Document MHWK000020120914e89h0002g

Medical Research; Investigators at Linkoping University Have Published New Data on Medical Research

438 mots 17 septembre 2012

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2012 SEP 17 (NewsRx) -- By a News Reporter-Staff News Editor at Mental Health Weekly Digest -- Data detailed on Medical Research have been presented. According to news reporting from Linkoping, Sweden, by NewsRx journalists, research stated, "Lying is a common phenomenon amongst human beings. It seems to play a role in making social interactions run more smoothly."

The news correspondents obtained a quote from the research from Linkoping University, "Too much honesty can be regarded as impolite or downright rude. Remarkably, lying is not a common phenomenon amongst normally intelligent human beings who are on the autism spectrum. They appear to be 'attractively morally innocent' and seem to have an above average moral conscientious objection against deception. In this paper, the behavior of persons with autism with regard to deception and truthfulness will be discussed in the light of two different ethical theories, illustrated by fragments from autobiographies of persons with autism. A systemizing 'Kantian' and an empathizing 'ethics of care' perspective reveal insights on high-functioning autism, truthfulness and moral behavior. Both perspectives are problematic from the point of view of a moral agent with autism. High-functioning persons with autism are, generally speaking, strong systemizes and weak empathizers. Particularly, they lack 'cognitive empathy' which would allow them to understand the position of the other person. Instead, some tend to invent a set of rules that makes their behavior compatible with the expectations of others. From a Kantian point of view, the autistic tendency to always tell the truth appears praiseworthy and should not be changed, though it creates problems in the social life of persons with autism. From a care ethics perspective, on the other hand, a way should be found to allow the high-functioning persons with autism to respect the feelings and needs of other persons as sometimes overruling the duty of truthfulness."

According to the news reporters, the researchers concluded: "We suggest this may even entail 'morally educating' children and adolescents with autism to become socially skilled empathic 'liars'."

For more information on this research see: Living the categorical imperative: autistic perspectives on lying and truth telling-between Kant and care ethics. Medicine, Health Care, and Philosophy, 2012;15(3):271-7.

Our news journalists report that additional information may be obtained by contacting P. Jaarsma, Division of Health and Society, IMH, University of Linkoping, Linkoping, Sweden.

Keywords for this news article include: Sweden, Europe, Autism, Linkoping, Neurology, Medical Research, Developmental Disabilities.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2012, NewsRx LLC

Document MHWK000020120914e89h0002k

Autism; Investigators from University of New Mexico Release New Data on Autism

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2012 SEP 17 (NewsRx) -- By a News Reporter-Staff News Editor at Mental Health Weekly Digest -- Investigators publish new report on Autism. According to news reporting out of Albuquerque, New Mexico, by NewsRx editors, research stated, "In the rubber hand illusion, perceived hand ownership can be transferred to a rubber hand after synchronous visual and tactile stimulation. Perceived body ownership and self-other relation are foundational for development of self-awareness, imitation, and empathy, which are all affected in autism spectrum disorders (ASD)."

Our news journalists obtained a quote from the research from the University of New Mexico, "We examined the rubber hand illusion in children with and without ASD. Children with ASD were initially less susceptible to the illusion than the comparison group, yet showed the effects of the illusion after 6 minutes. Delayed susceptibility to the illusion may result from atypical multisensory temporal integration and/or an unusually strong reliance on proprioception. Children with ASD who displayed less empathy were significantly less likely to experience the illusion than those with more intact ability to express empathy."

According to the news editors, the researchers concluded: "A better understanding of body representation in ASD may elucidate neural underpinnings of social deficits, thus informing future intervention approaches."

For more information on this research see: The rubber hand illusion in children with autism spectrum disorders: delayed influence of combined tactile and visual input on proprioception. Autism, 2012;16(4):406-419. Autism can be contacted at: Sage Publications Ltd, 1 Olivers Yard, 55 City Road, London EC1Y 1SP, England. (Sage Publications - www.sagepub.com/; Autism - aut.sagepub.com)

Our news journalists report that additional information may be obtained by contacting C.J. Cascio, University of New Mexico, Center Dev & Disabil, Albuquerque, NM 87131, United States.

Keywords for this news article include: Autism, Neurology, New Mexico, Pediatrics, Albuquerque, United States, North and Central America, Developmental Disabilities

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2012, NewsRx LLC

Document MHWK000020120914e89h0002o

Autism; Mahidol University Details Research in Autism

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2012 SEP 17 (NewsRx) -- By a News Reporter-Staff News Editor at Mental Health Weekly Digest -- A new study on Autism is now available. According to news reporting out of Bangkok, Thailand, by NewsRx editors, research stated, "This study aimed to examine the effectiveness of a translated version of the short version of the Developmental, Dimensional and Diagnostic Interview (3Di) in discriminating children with autism spectrum disorders (ASDs) from typically developing children. Two groups, comprising 63 children with clinically ascertained ASDs and 67 typically developing children, were interviewed with the short 3Di translated version."

Our news journalists obtained a quote from the research from Mahidol University, "Mean 3Di scale scores in each domain of autistic symptoms (social reciprocity, communication, and repetitive/stereotyped behaviors) were significantly higher in the ASD group than in the typically developing group. The optimal receiver operating characteristics curve cut-off scores were found to be 10, 8, and 3 for social reciprocity domain, communication domain, and repetitive/stereotyped behaviors domain, respectively, which are identical to the original English standardization. Corresponding sensitivities and specificities were 76.2% and 80.9% for the social reciprocity domain; 85.7% and 73.5% for the communication domain; and 66.7% and 80.9% for the repetitive behaviors domain. The areas under the curve were 0.89 (95% CI = 0.84- 0.94), 0.88 (95% CI = 0.82-0.94), and 0.79 (95% CI = 0.71-0.87), respectively."

According to the news editors, the researchers concluded: "The short 3Di-Thai version is found to be a useful diagnostic instrument for differentiating between clinically diagnosed children with ASDs and typically developing children, although further replication is needed."

For more information on this research see: Translation and validation of the developmental, dimensional and diagnostic interview (3Di) for diagnosis of autism spectrum disorder in Thai children. Autism, 2012;16(4):350-356. Autism can be contacted at: Sage Publications Ltd, 1 Olivers Yard, 55 City Road, London EC1Y 1SP, England. (Sage Publications - www.sagepub.com/; Autism - aut.sagepub.com)

Our news journalists report that additional information may be obtained by contacting J. Chuthapisith, Mahidol University, Bangkok 10700, Thailand.

Keywords for this news article include: Asia, Autism, Bangkok, Thailand, Neurology, Pediatrics, Developmental Disabilities

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2012, NewsRx LLC

Document MHWK000020120914e89h0002q

Autism; New Autism Study Findings Recently Were Reported by Researchers at Ghent University

295 mots 17 septembre 2012

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2012 SEP 17 (NewsRx) -- By a News Reporter-Staff News Editor at Mental Health Weekly Digest -- New research on Autism is the subject of a report. According to news reporting from Ghent, Belgium, by NewsRx journalists, research stated, "Previous studies on autism have shown a lack of motor anticipation in children and adults with autism. As part of a programme of research into early detection of autism, we focussed on an everyday situation: spoon-feeding."

The news correspondents obtained a quote from the research from Ghent University, "We hypothesize that an anticipation deficit may be found very early on by observing whether the baby opens his or her mouth in anticipation of the spoon's approach. The study is based on a retrospective analysis from family home movies."

According to the news reporters, the researchers concluded: "Observation of infants later diagnosed with autism or an autism spectrum disorder (ASD) (n = 13) and infants with typical development (n = 14) between 4 and 6 months old show that the autism/ASD group has an early anticipation deficit."

For more information on this research see: Motor anticipation failure in infants with autism: a retrospective analysis of feeding situations. Autism, 2012;16(4):420-429. Autism can be contacted at: Sage Publications Ltd, 1 Olivers Yard, 55 City Road, London EC1Y 1SP, England. (Sage Publications - www.sagepub.com/; Autism - aut.sagepub.com)

Our news journalists report that additional information may be obtained by contacting J. Brisson, University of Ghent, Res Grp Dev Disorders, Ghent, Belgium.

Keywords for this news article include: Ghent, Europe, Autism, Belgium, Neurology, Developmental Disabilities

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2012, NewsRx LLC

Document MHWK000020120914e89h0002t

Autism; New Findings Reported from Washington University Describe Advances in Autism

353 mots 17 septembre 2012

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2012 SEP 17 (NewsRx) -- By a News Reporter-Staff News Editor at Mental Health Weekly Digest -- Fresh data on Autism are presented in a new report. According to news reporting originating in St. Louis, Missouri, by NewsRx journalists, research stated, "Although motor impairment is frequently observed in children with autism spectrum disorders (ASD), the manner in which these impairments aggregate in families affected by autism is unknown. We used a standardized measure of motor proficiency to objectively examine quantitative variation in motor proficiency in sibling pairs concordant and discordant for ASD."

The news reporters obtained a quote from the research from Washington University, "Motor impairment of sibling pairs from 67 ASD-affected families comprising 29 concordant pairings and 48 discordant pairings were assessed using the Bruininks Oseretsky Test of Motor Proficiency, 2nd Edition, a standardized measure of motor proficiency. Motor skills were substantially impaired among ASD-affected children and highly correlated with autistic severity and IQ, whereas motor skills in unaffected siblings were essentially normal. Total motor composite scores of at least one standard deviation below the general population mean were seen in 83% of the affected group compared with 6% in the unaffected siblings."

According to the news reporters, the researchers concluded: "Findings indicate that motor impairment constitutes a core characteristic of ASD (not necessarily an ASD endophenotype), which has distinct implications for taxonomy, diagnosis, and approaches to intervention."

For more information on this research see: Motor impairment in sibling pairs concordant and discordant for autism spectrum disorders. Autism, 2012;16(4):430-441. Autism can be contacted at: Sage Publications Ltd, 1 Olivers Yard, 55 City Road, London EC1Y 1SP, England. (Sage Publications - www.sagepub.com/; Autism - aut.sagepub.com)

Our news correspondents report that additional information may be obtained by contacting C.L. Hilton, Washington University, St Louis, MO, United States.

Keywords for this news article include: Autism, Missouri, St. Louis, Neurology, Pediatrics, United States, North and Central America, Developmental Disabilities

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2012, NewsRx LLC

Document MHWK000020120914e89h0002w

Autism; New Findings from Duke University in the Area of Autism Published

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2012 SEP 17 (NewsRx) -- By a News Reporter-Staff News Editor at Mental Health Weekly Digest -- Investigators discuss new findings in Autism. According to news reporting originating in Durham, North Carolina, by NewsRx journalists, research stated, "Several lines of evidence support the view that autism is a typical member of a large family of immune-related, noninfectious, chronic diseases associated with postindustrial society. This family of diseases includes a wide range of inflammatory, allergic, and autoimmune diseases and results from consequences of genetic/culture mismatches which profoundly destabilize the immune system."

The news reporters obtained a quote from the research from Duke University, "Principle among these consequences is depletion of important components, particularly helminths, from the ecosystem of the human body, the human biome. Autism shares a wide range of features in common with this family of diseases, including the contribution of genetics/epigenetics, the identification of disease-inducing triggers, the apparent role of immunity in pathogenesis, high prevalence, complex etiologies and manifestations, and potentially some aspects of epidemiology. Fortunately, using available resources and technology, modern medicine has the potential to effectively reconstitute the human biome, thus treating or even avoiding altogether the consequences of genetic/cultural mismatches which underpin this entire family of disease."

According to the news reporters, the researchers concluded: "Thus, if indeed autism is an epidemic of postindustrial society associated with immune hypersensitivity, we can expect that the disease is readily preventable."

For more information on this research see: Is autism a member of a family of diseases resulting from genetic/cultural mismatches? Implications for treatment and prevention. Autism Research and Treatment, 2012;2012():910946. (Hindawi Publishing - www.hindawi.com; Autism Research and Treatment - www.hindawi.com/journals/aurt/)

Our news correspondents report that additional information may be obtained by contacting S.D. Bilbo, Systems and Integrative Neuroscience Group, Dept. of Psychology and Neuroscience, Duke University, Durham, NC 27710, United States.

Keywords for this news article include: Durham, Autism, Genetics, Neurology, Technology, United States, North Carolina, North and Central America, Developmental Disabilities.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2012, NewsRx LLC

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Mental Health; New Mental Health Findings from University of Missouri Described

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2012 SEP 17 (NewsRx) -- By a News Reporter-Staff News Editor at Mental Health Weekly Digest -- Research findings on Mental Health are discussed in a new report. According to news reporting originating in Columbia, Missouri, by NewsRx journalists, research stated, "Research has shown that parent education programs can address some of the distinct challenges that parents of youth with autism spectrum disorders (ASDs) encounter. This study examined the effectiveness of the Social Competence Intervention for Parents (SCI-P), a parent education program, administered in conjunction with a social competence intervention that targeted youth with ASD ages 11-14 (SCI-A)."

The news reporters obtained a quote from the research from the University of Missouri, "Using a quasi- experimental pre-post design, parents were assigned to either the SCI-P group (n=16) or to the waitlist comparison group (n=10). Analyses of covariance (ANCOVAs) revealed a significant effect for parent education participation such that SCI-P participants experienced significantly greater reductions in levels of stress and a trend for increases in parenting sense of competence from pre-to post-intervention. Moreover, parents in the SCI-P group reported high satisfaction with the program."

According to the news reporters, the researchers concluded: "These findings suggest that parent education can result in positive outcomes for parents' well being."

For more information on this research see: Social Competence Intervention for Parents (SCI-P):

Comparing Outcomes for a Parent Education Program Targeting Adolescents with ASD. Autism Research and Treatment, 2012;2012():681465. (Hindawi Publishing - www.hindawi.com; Autism Research and Treatment - www.hindawi.com/journals/aurt/)

Our news correspondents report that additional information may be obtained by contacting T.R. Schultz, Dept. of Special Education, University of Missouri, Columbia, MO 65211, United States.

Keywords for this news article include: Columbia, Missouri, United States, Mental Health, North and Central America.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2012, NewsRx LLC

Document MHWK000020120914e89h00030

Autism; Recent Findings in Autism Described by Researchers from Johns Hopkins University School of Medicine

376 mots 17 septembre 2012

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2012 SEP 17 (NewsRx) -- By a News Reporter-Staff News Editor at Mental Health Weekly Digest -- Investigators publish new report on Autism. According to news reporting originating from Baltimore, Maryland, by NewsRx correspondents, research stated, "Mood disorders occur more frequently in family

members of individuals with autism spectrum disorders (ASD) than in the general population. There may

be associations between maternal mood disorder history patterns and specific ASD phenotypes."

Our news editors obtained a quote from the research from the Johns Hopkins University School of Medicine, "We therefore examined the relationship between maternal mood disorders and child autism spectrum disorders in 998 mother-child dyads enrolled in a national online autism registry and database. Mothers of children with ASD completed online questionnaires addressing their child's ASD as well as

their own mood disorder history. In multivariate logistic regression models of ASD diagnoses, the odds of

an Asperger disorder versus autistic disorder diagnosis were higher among those children whose mothers

had a lifetime history of bipolar disorder (OR 2.11, CI 1.20, 3.69) or depression (OR 1.62, CI 1.19, 2.19). Further, maternal mood disorder onset before first pregnancy was associated with higher odds (OR 2.35,

CI 1.48, 3.73) of an Asperger versus autism diagnosis among this sample of children with ASD."

According to the news editors, the researchers concluded: "These data suggest that differences in maternal mood disorder history may be associated with ASD phenotype in offspring."

For more information on this research see: Mood disorders in mothers of children on the autism spectrum are associated with higher functioning autism. Autism Research and Treatment, 2012;2012():435646. (Hindawi Publishing - www.hindawi.com; Autism Research and Treatment - www.hindawi.com/journals/aurt/)

The news editors report that additional information may be obtained by contacting R.A. Vasa, Dept. of

Psychiatry, Kennedy Krieger Institute, Johns Hopkins University School of Medicine, 3901 Greenspring Avenue, Baltimore, MD 21211, United States.

Keywords for this news article include: Autism, Maryland, Baltimore, Neurology, Pediatrics, United States, North and Central America, Developmental Disabilities.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2012, NewsRx LLC

Document MHWK000020120914e89h0003l

Autism; Reports Outline Autism Research from C.J. Dunst and Colleagues

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2012 SEP 17 (NewsRx) -- By a News Reporter-Staff News Editor at Mental Health Weekly Digest -- New research on Autism is the subject of a report. According to news reporting originating in Asheville, North Carolina, by NewsRx journalists, research stated, "Incorporating the interests and preferences of young children with autism spectrum disorders into interventions to promote prosocial behavior and decrease behavior excesses has emerged as a promising practice for addressing the core features of autism. The efficacy of interest-based early intervention practices was examined in a meta-analysis of 24 studies including 78 children 2 to 6 years of age diagnosed with autism spectrum disorders."

The news reporters obtained a quote from the research, "Effect size analyses of intervention versus nonintervention conditions and high-interest versus low-interest contrasts indicated that interest-based intervention practices were effective in terms of increasing prosocial and decreasing aberrant child behavior. Additionally, interest-based interventions that focused on two of the three core features of autism spectrum disorders (poor communication, poor interpersonal relationships) were found most effective in influencing child outcomes."

According to the news reporters, the researchers concluded: "Implications for very early intervention are discussed in terms addressing the behavior markers of autism spectrum disorders before they become firmly established."

For more information on this research see: Meta-analysis of studies incorporating the interests of young children with autism spectrum disorders into early intervention practices. Autism Research and Treatment, 2012;2012():462531. (Hindawi Publishing - www.hindawi.com; Autism Research and Treatment - www.hindawi.com/journals/aurt/)

Our news correspondents report that additional information may be obtained by contacting C.J. Dunst, Orelena Hawks Puckett Institute, 8 Elk Mountain Road, Asheville, NC 28804, United States.

Keywords for this news article include: Autism, Asheville, Neurology, Pediatrics, United States, North Carolina, North and Central America, Developmental Disabilities.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2012, NewsRx LLC

Document MHWK000020120914e89h0003n

Medical Research; Reports from Hobart and William Smith Colleges Highlight Recent Research in Medical Research

273 mots 17 septembre 2012

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2012 SEP 17 (NewsRx) -- By a News Reporter-Staff News Editor at Mental Health Weekly Digest -- Researchers detail new data in Medical Research. According to news originating from Geneva, New York, by NewsRx correspondents, research stated, "Substantial research efforts have been devoted to developing a cure for autism, but some advocates of people with autism claim that these efforts are misguided and even harmful. They claim that there is nothing wrong with people with autism, so there is nothing to cure."

Our news journalists obtained a quote from the research from Hobart and William Smith Colleges, "Others argue that autism is a serious and debilitating disorder and that a cure for autism would be a wonderful medical breakthrough. Our goal in this essay is to evaluate what assumptions underlie each of these positions."

According to the news editors, the researchers concluded: "We evaluate the arguments made on each side, reject those that are implausible and then highlight the key assumptions of those that remain."

For more information on this research see: Should we welcome a cure for autism? A survey of the arguments. Medicine, Health Care, and Philosophy, 2012;15(3):255-69.

The news correspondents report that additional information may be obtained from R.E. Barnes, Philosophy Department, Hobart & William Smith Colleges, Geneva, NY 14456, United States.

Keywords for this news article include: Geneva, Autism, New York, Neurology, United States, Medical Research, North and Central America, Developmental Disabilities.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2012,

NewsRx LLC

Document MHWK000020120914e89h0003q

Autism and Developmental Disorders; Studies from National Taiwan University in the Area of Autism and Developmental Disorders Described

360 mots 17 septembre 2012

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2012 SEP 17 (NewsRx) -- By a News Reporter-Staff News Editor at Mental Health Weekly Digest -- Current study results on Autism and Developmental Disorders have been published. According to news reporting originating from Taipei, Taiwan, by NewsRx correspondents, research stated, "No feasible screening instrument is available for early detection of children with autism in Taiwan. The existing instruments may not be appropriate for use in Taiwan due to different health care systems and child- rearing cultures."

Our news editors obtained a quote from the research from National Taiwan University, "The purpose of this study was to develop and test a screening questionnaire for generic autism. The initial 18-item screening questionnaire was developed by a child psychiatrist using face-to-face interviews with 10 families of children with autism and then tested on a sample of families of 18 children with autism and of 59 typically developing children. Of these 18 items, 15 had fair or better item discrimination (kappa > 0.20) and were selected for the revised screening questionnaire. In the revised questionnaire, cutoff scores of 5 and 6 offered 100% sensitivity and 96.5% specificity, with the area under the receiver operating characteristic curve of 0.983. The revised screening instrument has high sensitivity and specificity, making it potentially useful for screening Taiwanese children at risk for autism."

According to the news editors, the researchers concluded: "This instrument should be further tested in a population-based study."

For more information on this research see: Toddler autism screening questionnaire: Development and potential clinical validity. Autism, 2012;16(4):340-349. Autism can be contacted at: Sage Publications Ltd, 1 Olivers Yard, 55 City Road, London EC1Y 1SP, England. (Sage Publications - www.sagepub.com/; Autism - aut.sagepub.com)

The news editors report that additional information may be obtained by contacting W.C. Tsai, National Taiwan University, Taipei, Taiwan.

Keywords for this news article include: Asia, Taipei, Taiwan, Neurology, Developmental Disabilities, Autism and Developmental Disorders

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2012, NewsRx LLC

Document MHWK000020120914e89h00055

Autism; Studies from Vanderbilt University Have Provided New Data on Autism

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2012 SEP 17 (NewsRx) -- By a News Reporter-Staff News Editor at Mental Health Weekly Digest -- Data detailed on Autism have been presented. According to news reporting originating in Nashville, Tennessee, by NewsRx journalists, research stated, "A randomized control trial comparing two social communication treatments for children with autism spectrum disorder examined the effect of treatment on object interest. Thirty-two children, 18-60 months, were randomly assigned to the Picture Exchange Communication System (PECS) or Responsive Education and Prelinguistic Milieu Teaching (RPMT) condition."

The news reporters obtained a quote from the research from Vanderbilt University, "Assessment of object interest was conducted in an unstructured play session with different toys, activities, adult, and location than experienced in treatment. Results indicated children in the RPMT condition showed greater increases in object interest as compared to children in the PECS condition."

According to the news reporters, the researchers concluded: "Because child characteristics such as interest in objects may influence response to interventions using object play as contexts for treatment, it is important to improve our understanding of whether intervention can affect object interest."

For more information on this research see: Object interest in autism spectrum disorder: A treatment comparison. Autism, 2012;16(4):398-405. Autism can be contacted at: Sage Publications Ltd, 1 Olivers Yard, 55 City Road, London EC1Y 1SP, England. (Sage Publications - www.sagepub.com/; Autism - aut.sagepub.com)

Our news correspondents report that additional information may be obtained by contacting A.S. Mcduffie, Vanderbilt University, Peabody College, Nashville, TN 37235, United States.

Keywords for this news article include: Autism, Nashville, Tennessee, Neurology, Pediatrics, United

States, North and Central America, Developmental Disabilities

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2012, NewsRx LLC

Document MHWK000020120914e89h00059

Autism and Developmental Disorders; Study Findings from University of Washington Provide New Insights into Autism and Developmental Disorders

318 mots 17 septembre 2012

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2012 SEP 17 (NewsRx) -- By a News Reporter-Staff News Editor at Mental Health Weekly Digest -- Researchers detail new data in Autism and Developmental Disorders. According to news reporting originating in Seattle, Washington, by NewsRx journalists, research stated, "This study reports on a new false belief measure in a sample of 124 children and adolescents with or without high functioning autism (HFASD). In the classic paradigm, a participant predicts in which of two discrete locations a deceived protagonist will look for an object."

The news reporters obtained a quote from the research from the University of Washington, "In the current Sandbox task, the object is buried and reburied in a sandbox, thus creating a continuum between locations. Compared to typically developing individuals (n=62), those with HFASD (n=62) showed a larger egocentric bias on the Sandbox task. They failed to take the protagonist's false belief into account, despite their adequate ability to infer advanced mental states."

According to the news reporters, the researchers concluded: "This indicates that sensitive measures can reveal subtle first order Theory of Mind impairments in HFASD individuals."

For more information on this research see: A continuous false belief task reveals egocentric biases in children and adolescents with Autism Spectrum Disorders. Autism, 2012;16(4):357-366. Autism can be contacted at: Sage Publications Ltd, 1 Olivers Yard, 55 City Road, London EC1Y 1SP, England. (Sage Publications - www.sagepub.com/; Autism - aut.sagepub.com)

Our news correspondents report that additional information may be obtained by contacting S. Begeer, University of Washington, Seattle, WA 98195, United States.

Keywords for this news article include: Seattle, Neurology, Washington, United States, North and Central

America, Developmental Disabilities, Autism and Developmental Disorders

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2012, NewsRx LLC

Document MHWK000020120914e89h0005c

Central Nervous System; Research on Central Nervous System Published by A. Chauhan et al

529 mots 17 septembre 2012

Pain & Central Nervous System Week PNWK

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2012 SEP 17 (NewsRx) -- By a News Reporter-Staff News Editor at Pain & Central Nervous System Week -- Investigators publish new report on Central Nervous System. According to news reporting originating in Staten Island, New York, by NewsRx journalists, research stated, "Autism is a heterogeneous, behaviorally defined neurodevelopmental disorder. Recently, we reported a brain region- specific increase in lipid peroxidation, and deficits in mitochondrial electron transport chain complexes in autism, suggesting the role of oxidative stress and mitochondrial dysfunction in the pathophysiology of autism."

The news reporters obtained a quote from the research, "However, the antioxidant status of the brain is not known in autism. Glutathione is a major endogenous antioxidant that plays a crucial role in protecting cells from exogenous and endogenous toxins, particularly in the central nervous system. The present study examines the concentrations of glutathione (GSH, reduced form; and GSSG, oxidized form) and the redox ratio of GSH to GSSG (marker of oxidative stress) in different regions of brains from autistic subjects and age-matched control subjects. In the cerebellum and temporal cortex from subjects with autism, GSH levels were significantly decreased by 34.2 and 44.6 %, with a concomitant increase in the levels of GSSG by 38.2 and 45.5 %, respectively, as compared to the control group. There was also a significant decrease in the levels of total GSH (tGSH) by 32.9 % in the cerebellum, and by 43.1 % in the temporal cortex of subjects with autism. In contrast, there was no significant change in GSH, GSSG and tGSH levels in the frontal, parietal and occipital cortices in autism versus control group. The redox ratio of GSH to GSSG was also significantly decreased by 52.8 % in the cerebellum and by 60.8 % in the temporal cortex of subjects with autism, suggesting glutathione redox imbalance in the brain of individuals with autism. These findings indicate that autism is associated with deficits in glutathione antioxidant defense in selective regions of the brain."

According to the news reporters, the researchers concluded: "We suggest that disturbances in brain

glutathione homeostasis may contribute to oxidative stress, immune dysfunction and apoptosis, particularly in the cerebellum and temporal lobe, and may lead to neurodevelopmental abnormalities in autism."

For more information on this research see: Brain region-specific glutathione redox imbalance in autism. Neurochemical Research, 2012;37(8):1681-9. Neurochemical Research can be contacted at: Springer, 233 Spring Street, New York, NY 10013, USA. (Springer - www.springer.com; Neurochemical Research -

Our news correspondents report that additional information may be obtained by contacting A. Chauhan, NYS Institute for Basic Research in Developmental Disabilities, 1050 Forest Hill Road, Staten Island NY 10314, United States.

The publisher of the journal Neurochemical Research can be contacted at: Springer, 233 Spring Street, New York, NY 10013, USA.

Keywords for this news article include: Antioxidants, New York, Brain Stem, Cerebellum, Glutathione, Staten Island, United States, Metencephalon, Oligopeptides, Protective Agents, Central Nervous System, North and Central America.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2012, NewsRx LLC

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