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Riyadh branch - Al Malaz - Al Hwari st. - 1st floor - Office No.2 Tel: +966 8 11 14 24 332 Fax: +966 8 11 10 11 149 Mob: +966 5 41 31 6050 P.O.Box: 15428 Jeddah 21444 KSA E-mail: info@ds-sa.me Diamond Spectrum for Scientific & Laboratory Equipment est. Jeddah branch - Al Batrji st. Al Zahraa district - Hammam Commercial Center - 2nd floor Office No.11 Tel: +966 2 69 19 740 Fax: +966 2 66 73 443 Mob: +966 5 41 31 6050 P.O.Box: 15428 Jeddah 21444 KSA E-mail: info@ds-sa.me
Company Products
Catalogue 2012/13
IVF lab Genetics lab Microscopy Medical Software Environment Monitoring Disposables & Consumables Service & Support
Jordan Office
Taawon for Laboratory & Scientific Supplies Amman - Jabal Amman - Abed AlMunam Riyadh st. - Building No.24 - 1st floor - Office No.1 Tel: Fax: Mob: P.O.Box: E-mail: +962 6 46 54 704 +962 6 46 54 705 +962 7 77 48 5766 840281 Amman 11181 Jordan info@taawon.me
www.taawon.me
Table of contents
Introduction
IVF Line 4
Taawon and Diamond Spectrum are sister companies specialized in supplying equipment and providing turn-key solutions for IVF and Genetic laboratories. Equipped with many years of experience and a dedicated team, we have grown significantly to match the expanding needs for newer technologies and more specialized services in the Middle East Market. We care to offer tailored services fulfilling customers unique needs, Today, our scope of services covers Labs Environment Measurement, Lab Design, Instruments & Disposables Supply, Commissioning, Quality Control and Specialized Training. Our main lines consisted of: - IVF Labs - Genetics Labs - Microscopy - Medical Software - Environment Monitoring - Disposables & Consumables - Service & Support Now we are proud to be a key supplier for Fertility Labs, Genetics labs and Bio Research Centers.
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Perfect combination
Our emphasis on The NT-88-V3 series developed by NIKON & Narishige, Insures easy operation and unsurpassed level of precision. When used with well known Nikons high performance Eclipse Ti microscope with newly developed NAMC (Nikon Advanced Modulation Contrast) observation technique specialized for IVF application, it provides the strongest supported combination.
Growing business:
Since our very beginning, we have chosen to be a primary provider of innovative equipment and instrumentation for Embryologists and Genetists. To realize this objective, we have teamed up with the big names of IVF and Genetics labs instrumentation suppliers; hence, we offer a complete range of equipment. We also work in close cooporation with specialists in these fields, which allows us to continuously expand our range of services by always being up-to-date with the latest developments.
Our emphasis on service is a key element to our success. Our definition of good service goes beyond installation and repair covering our commitment to provide prompt response to customer needs and to ensure adequate customer training. Also the integration of Quality Control Management to our line of services by offering specialized instrument for measuring and monitoring critical conditions and offering solution for control.
We proud to help Gynecologists and Embryologists to set up their own IVF labs. Our services include: Consulting and planning including lab design, sterility consideration and costing studies. A to Z supplies of all modern labs items, including equipment and consumables. Installation and commissioning of equipment and instrumentation, which are done by our qualified, well-trained technicians. Training of staff on operating equipment as well as on procedures. Offering quality program which include environmental and instruments monitoring & control.
MedITEX IVF is a software application that meets all daily requirements in your IVF routines and practices, it helps physicians, embryologists and their teams in all areas of diagnostics and lab work.
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Ti ICSI station
Our ICSI station is based on Nikon Ti inverted microscope, Narishige micromanipulators, TokaiHit glass hotstage and the Nikon NAMC objectives.
NAMC stand for Nikon Advanced Modulation Contrast, those are specially designed by Nikon for IVF application, they produce crisp and clear 3D-Like images for live specimens regardless of the dish type, and a new addition to IVF objectives is the IMSI objective which is designed for IMSI observation under normal ICSI setup.
Ti Microscopes
TokaiHit hotstage
While using fans helps to mix the CO2 gas, it still pose a danger of spreading infections, not to mention cleaning difficulties, with Binder patented gas mixing head those issues are solved
Advance preheating technology (ATP) conditions the incubator air before it is blown toward the jacket, resulting is faster temp. recovery times and uniform heat distribution
Narishige manipulators
A unique patent design where a cold pan at room temp. is integrated inside the humidity pan, this eliminates the risk of condensation on the incubator walls minimizing contamination risk
Narishige micromanipulator NT-88-V3 made especially for Nikon, Feature both hydraulic fine movement and electrical fine and course movement, this combination give the ICSI both the flexibility and the reliability needed for IVF work, the hanging joystick give flexible and natural feeling for best manipulation.
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Binder employs dual beam-dual sensor technology compensate for lamp light intensity drift, this eliminates the need for frequent CO2 calibration and assure stable CO2 control.\
Undisturbed Incubation
EmbryoSlide
Research has shown that changes in temperature, pH and exposure to light may be damaging to embryo development, also manipulation of embryos increase risk of accidents and contamination. EmbryoScope allows for safe observation of embryos, all of the time without ever disturbing incubation conditions or stressing the embryos.
The EmbryoSlide is a unique dish with 12 well, made from special optical polymer which can be used for normal microscopy and laser, each well is marked with micro numerals for identification.
A novel invention Why does it improve pregnancy rate? Undisturbed Incubation Inside the EmbryoScope EmbryoSlide Evaluation & documentation
Pregnancy rate depends to a large extent on embryo quality. EmbryoScope achieves a much more stable incubation, allowing us to obtain higher quality embryos, by not having to take the embryos out of the incubator, there arent any changes in the temperature or moisture levels of the culture. Furthermore, we receive a lot more information from the embryo and we can detect morphological abnormalities in the embryo which we were not able to detect before. Cell division rates have proved to be a good marker for predicting the possibilities of implanting an embryo. With EmbryoScope, the possibility of gestation is enhanced by 20% thanks to all of these factors being taken in to consideration A study made by IVI clinics - Spain, in 2011 to compare the outcome of embryoscope cycles and standard incubate cycles, The following are selection criteria and the results:
N= 1629 N= 1629 N= 7176 N= 7176
Embryo settles to the bottom of the well. Conical sides of the well automatically place the embryo in a central depression this secure embryo in its position. Each well have a volume of 25 L which is secure to prevent embryo movement & suitable for handling media without disturbing the embryos. EmbryoScope incorporates a tri-gas incubator that mixes and control the concentration of CO2 and O2 , the design features continuous gas circulation and sterilization with UV light decontamination, HEPA particle filter, VOC carbon filter, all of this will minimal gas consumption of <1.0 L CO2/hr), and fast gas recovery.
A novel invention
Time-laps enable the dynamic observation for better decision about which embryo to transfer, now you can have idea about the timing of cleavages, synchrony of divisions, fragmentation history, appearance of nuclei and detection of multinucleation.
IVF lab Office Internet
Currently, assessment of embryo development in IVF is limited to brief snap-shot glimpses at defined time points, in order to minimize disturbances to culture conditions. However embryo development is a dynamic process and a wealth of information about embryo development history remains untapped.
Only transfer on Day 3 (72h) or Day 5 (120h). Only ICSI. BMI 30 for autologous cycles No Endometriosis for autologous cycles Mature oocytes retrieved > 0 The outcome of this study is clinical pregnancy confirmed by ultrasound w7
Unique temperature control by direct heat transfer to individual media filled wells. Temperature is virtually unchanged by opening chamber (<0.2 oC). Dry incubation without water pans eliminates problems with water condensation and fungal growth on surfaces in high humidity.
EmbryoScope Microscope (BF)
0 100 200 300
This evaluation can be done on the instrument or remotely at any time, this means improved time and resource management, and the ability to consult colleagues for external evaluation.
The EmbryoScope Time-lapse System provides a safe, controlled culture environment, while allowing continuous monitoring and observation of up to 72 embryos at a time. The instrument provides a unique opportunity to develop new parameters for future embryo scoring.
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From 7243 cycles from which 1370 in EmbryoScope. Result shows significant improve (17%) when using EmbryoScope.
EmbryoScope uses special low energy (1w red led) light source with very short illumination time for each image (< 100 ms), which reduces the stress caused by high intensity light used in conventional microscopes.
Time-lapse analysis image files and all incubation parameters are automatically stored with the patient file for review at any time. Knowledge built though retrospective can now be used as to build new selection criteries for future embryos to choose.
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Highest optical magnification. Dry long working distance objective. High resolution 3D imaging. Binocular view. Simple switching between ICSI & IMSI. ___________________________________________________
IMSI is an optical technique that requires high magnification with high resolution, as optical magnification is better than digital magnification; Nikon IMSI solution utilize 100x magnifying objective to get the best possible images.
Since 100x objective and high resolution 3D images is used; there is no need to view your IMSI specimen through an external monitor, with Nikon IMSI solution, IMSI is performed on the microscope binoculars without the need to switch your view to the camera monitor, not only this makes operation easier but also gives the advantage of the big field of view from the binoculars, enabling many sperm morphology analysis in one shot.
While the use of 100x objective is a key feature to get best magnification, the use of oil and the reduction of working distance is typically associated with high magnification, but for IMSI dry and long working distance objectives are needed to ensure sterility, ease of use and the use of hot glass stages, Nikon has designed a special objective to meet those IMSI requirement.
To view vacuoles, 3D imaging technique is needed, typically two ways are possible, oblique illumination and DIC, while the first one compromises the resolution, Nikon IMSI
In routine IVF work, embryologist need to be focused on his biological work not microscope setup, with this in mind, Nikon IMSI solutions offers simple switching between IMSI view and regular ICSI view, just rotate the nose piece to change the view.
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Built into the objective No alignment of laser optics required Lowest heat impact Temperature spread visualized Comprehensive software & reporting
Hamilton Thorne laser is designed with the specimen safety as the the most important criteria, utilizing high power laser and factory aligned laser optics integrated into the laser objective, this assured the shortest time is needed to make the proper laser shots, and there by reducing the heat impact from the laser to minimum.
With DICOM solution you will be able to achieve perfect communication between MedITEX IVF and ultrasound devices of various manufacturers.
MedITEX IVF is a software application that meets all daily requirements in your IVF routines and practices, it helps physicians, embryologists and their teams in all areas of diagnostics and lab work.
With laser integrated as part of the objective lenses, it guarantees optical alignment with objective lenses and provides protection against dust and sastain the optical alignment for the life time of the laser.
The patented isothermal ring are validated algorithm which calculate how far the dangerous heat resulting from the laser shots will spread deep into the specimen, giving the user the proper indication about the safety of his shot.
MedITEX billing
The MedITEX IVF Online Portal is a web-based information tool which enable your patients to request any information on the status of their treatment online at any time.
The Billing module can automatically generate all relevant billing positions, based on data collected in MedITEX IVF and exported to an external accounting program or billed directly.
Use the MedITEX RFID Connector to automate and the resources, operations and processes in terms of quality and efficiency. RFID (radio frequency identification) enables the contactless, identification and localization of objects and human beings.
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Nikon microscope
Offering our microscopes from Nikon the world leader in imaging technology since 1917, Nikon Instruments manufactures complete optical and digital microscope systems with outstanding versatility, performance and productivity for any application.
Ni-Ci Series
All of these features can be configured for the latest Ni microscope line, which also offers many options like motorization, different illuminations systems, integration with Imaging software, and many more
The Ni series combination with Lucia Cytogenetic Software is the ultimate in upright biological microscope evolution, supports bioscience studies with enhanced basic performance and flexible system expandability and in the ease of use and the speed of getting results. Ni series accessories are segmented by function, allowing you to select required units and flexibly combine them to create lean and effective system configurations.
For cytogentics microscopes Nikon solutions is unique for its specialized Objectives Like the Karyotyping objective and the Super fluorecent objectives, also Nikon offer the unique noise termination technology for fluorecent imaging, all of these innovations contributes have a microscopes with tangible differences compared to the normal microscope.
We are proud to help Gynecologists, Embryologists and Genetists to set up their own IVF/ Genetics labs. Our services include: Consulting and planning including lab design, sterility consideration and costing studies. A to Z supplies of all modern labs items, including equipment and consumables. Installation and commissioning of equipment and instrumentation, which are done by our qualified, well-trained technicians. Training of staff on operating equipment as well as on procedures. Offering quality program which include environmental and instruments monitoring & control.
Since 1990, Laboratory Imaging have been developing image analysis software applications. Lucia the cytogenetic imaging systems offered by LIM offer a comprehensive platform for cytogenetic labs covering all the needed task, but is also it adds unique features such as modularity, and Data Base archiving system
Lucia Karyo
stands out in the ease of use and the speed of getting results. Beside the image analysis functionality it provides a tool for both automatic and manual report generation and very powerful and flexible database.
Lucia FISH/mFISH
Capturing is the crucial feature of each fluorescence imaging system. LUCIA applications incorporate lots of possibilities helping to obtain optimal image quality. Taking care for the choice of the camera, image accusation and processing
Our emphasis on service is a key element to our success. Our service coverage in this field is similar to what we offer in IVF labs, again we find good service more than installation and repair covering our commitment to provide prompt response to customer needs and to ensure adequate customer training.== Collaboration with reference laboratories in Czech republic and in Jordan to offer our customers training service costumed to his need, a special program is also available to train genitests for karyotyping application.
The Metaphase Finder system consists of carefully selected top quality hardware components all produced by well-established manufacturers. In a very compact setup, the setup offers flexibility comfort and seamless work flow
Ideal for denaturation and hybridization of fluorescent in situ hybridization procedures. This programmable system automates the denaturation and hybridization steps in slide-based (F) ISH procedures, and provides walk-away convenience for clinical and research personnel. The low cost unit accepts a wide range of sample types, is easy to use, and reduces hands-on time by more than 50% while ensuring overall precision and accuracy in all (F)ISH assays.
Microarray
Microarray technology has greatly contributed to research in many areas including functional biology, genomics, transcriptomics, and proteomics, both in plants and animals. Researchers worldwide continue to refine this technology with their ideas for novel applications.
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LUCIA Cytogenetics
Cytogenetics made simple!
Flexibility & Modularity
Lucia software is costumizable, you can easily define special idograms, probs and probs kit, filters, anotations, and microscopes. Also different windows views of the capture and of the specimen is possible Special tools like regional threshold editing, regional enhancing, chromosome compare functions and anotation tables are integrated.
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Less fluorescent noise Super fluorescent objectives Uniform bright ellumination Dedicated karyotyping objective
CFI super fluor lenses provide the highest ultraviolet transmission, exceptionally high N.A. , terrific chromatic correction, and outstanding transmission below 340nm, Also, these objectives have improved signal-to-noise (S/N) for short wavelengths, due to low auto-fluorescence materials, and have high N.A , making the fluorescence images they produce significantly sharper and brighter.
Lucia is a modular software which means user can buy the modules he need and add it later if needed, this include - Karyotyping, FISH, mFISH & Metaphase finder
Reports
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The noise terminator is installed to appropriately process excitation light (stray light) that passed through the dichroic mirror, thereby preventing the light from reflecting in the filter block and leaking into the observation side. This makes it possible to obtain fluorescence images with extremely low background noise and a high S/N ratio.
A single click is all what you need to capture images, Lucia will do rest, camera correction, and image correction or enhancement is done automatically if needed, for large images capture Lucia will guide you step-by-step to make the capture.
Report generating function is integrated with Lucia, now you can create template with reports and store them in the data base, just with a single click, your work is exported to the chosen report template and ready for printing or e-mailing. All reports generated are stored in the data base as well.
Automation software
Uniformity guaranteed
The fly-eye lens is ideally suited to diascopic illumination optical systems. Uniform and bright illumination up to the view field periphery is provided at any magnification.
CFI plan apochromat objective (NCG) specialized objectives for karyotyping application, this application takes the bright field microscopy to its maximum limitation as it requires the highest possible resolution at high magnification, and no use of cover glass. With these requierment in mind Nikon has designed the NCG 100x plan apo objective to deliver the best performance.
Automation is a key feature with Lucia whether it is threshold correction or image enhancement, all of that cat be automated. Separation never been so easy with semi-automated routines (clipping of touching or overlapping chromosomes). Trainable automated classifier which can adapt itself to your staining and banding.
Lucia incorporates Microsoft SQL data base, this powerful DB engine is needed to manage the added functionality of Lucia such as data integration (reports, templates, images, patient, sample, history, analysis are all integrated). Also SQL DB provides easy backup, filtering and classification function and statistical tools. This DB has virtually no size limit, so you can store as much cases as limit.
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Supplies:
Equipments supplies Supply of all IVF and cytogenetics laboratory equipment from leader manufactures Disposables and consumables supplies This include Media, Needles, Air quality filter, non toxic disinfectant, probs. Installation and commissioning As default we are responsible for the installation and commissioning of all of our supplies equipments, that also include staff training on the operation of those equipment.
Quality control measurements for the VOC (left) contamination and particle (right) contamination inside IVF work bench.
Repairing and disinfecting incubators, for incubators which does not have auto sterilization, a comprehensive disinfection required to dismantle the inner chamber for disinfecting.
This can be useful for the newly started IVF units, offering periodic visits of senior embryologist to advice and consult the unit, and help in tuning the operation in the unit consulting program can also be on specific routines
Quality control service We offer measurement for the following parameters: IVF lab Air Quality (VOC and Particles Count). Incubator gases CO2 , O2, Humidity and temperature mapping. Laminar flow sterility testing. Hot surfaces temperature. Consultancy service We offer our assistance in IVF unit design IVF Units design HVAC system design Sterility and Contamination control
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Laser optics alignment check, using special slides which indicate the quality of laser alignment.
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